Human Genome Epidemiology Literature Finder
Records 1 - 23 (of 23 Records) |
Query Trace: Neutropenia and ITPA[original query] |
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Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. Clinical pharmacology and therapeutics 2009 Feb 85 (2): 164-72. Stocco G, Cheok M H, Crews K R, Dervieux T, French D, Pei D, Yang W, Cheng C, Pui C-H, Relling M V, Evans W |
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.
Journal of hepatology 2012 Feb 56 (2): 313-9. Thompson Alexander J, Clark Paul J, Singh Abanish, Ge Dongliang, Fellay Jacques, Zhu Mingfu, Zhu Qianqian, Urban Thomas J, Patel Keyur, Tillmann Hans L, Naggie Susanna, Afdhal Nezam H, Jacobson Ira M, Esteban Rafael, Poordad Fred, Lawitz Eric J, McCone Jonathan, Shiffman Mitchell L, Galler Greg W, King John W, Kwo Paul Y, Shianna Kevin V, Noviello Stephanie, Pedicone Lisa D, Brass Clifford A, Albrecht Janice K, Sulkowski Mark S, Goldstein David B, McHutchison John G, Muir Andrew |
Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants. PloS one 2012 7 (11): e47725. Vidal Francesc, López-Dupla Miguel, Laguno Montserrat, Veloso Sergi, Mallolas Josep, Murillas Javier, Cifuentes Carmen, Gallart Lluis, Auguet Teresa, Sampériz Gloria, Payeras Antoni, Hernandez Pilar, Arnedo Mireia, Gatell Josep Ma, Richart Cristób |
Impact of Genetic Polymorphisms on 6-Thioguanine Nucleotide Levels and Toxicity in Pediatric Patients with IBD Treated with Azathioprine. Inflammatory bowel diseases 2015 Aug . Lee Mi-Na, Kang Ben, Choi So Yoon, Kim Mi Jin, Woo Sook Young, Kim Jong-Won, Choe Yon Ho, Lee Soo-Yo |
Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia patients. Pharmacogenomics 2015 Jul 16 (10): 1119-34. Hareedy Mohammad Salem, El Desoky Ehab S, Woillard Jean-Baptiste, Thabet Romany Helmy, Ali Amany Mohamad, Marquet Pierre, Picard Nicol |
Genetic Predictors of Azathioprine Toxicity and Clinical Response in Patients with Inflammatory Bowel Disease. Journal of population therapeutics and clinical pharmacology = Journal de la the?rapeutique des populations et de la pharamcologie clinique 2016 23 (1): e26-36. Al-Judaibi B, Schwarz U I, Huda N, Dresser G K, Gregor J C, Ponich T, Chande N, Mosli M, Kim R |
Role of inosine triphosphate pyrophosphatase gene variant on fever incidence during zidovudine antiretroviral therapy. Genetics and molecular research : GMR 2017 Jan 16 (1): . Coelho A V C, Silva S P S, Zandonà L, Stocco G, Decorti G, Crovella |
Prevalence of TPMT, ITPA and NUDT 15 genetic polymorphisms and their relation to 6MP toxicity in north Indian children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 2019 Feb 83 (2): 341-348. Khera Sanjeev, Trehan Amita, Bhatia Prateek, Singh Minu, Bansal Deepak, Varma Neel |
ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia. Frontiers in pharmacology 2019 9 10 916. Moradveisi Borhan, Muwakkit Samar, Zamani Fatemeh, Ghaderi Ebrahim, Mohammadi Ebrahim, Zgheib Nathalie |
Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia. British journal of clinical pharmacology 2019 Mar . Choi Rihwa, Sohn Insuk, Kim Min-Ji, Woo Hye In, Lee Ji Won, Ma Youngeun, Yi Eun Sang, Koo Hong Hoe, Lee Soo-Yo |
The Role of TPMT, ITPA, and NUDT15 Variants during Mercaptopurine Treatment of Swedish Pediatric Patients with Acute Lymphoblastic Leukemia. The Journal of pediatrics 2019 10 216 150-157.e1. Wahlund Martina, Nilsson Anna, Kahlin Anna Zimdahl, Broliden Kristina, Myrberg Ida Hed, Appell Malin Lindqvist, Berggren An |
Childhood acute lymphoblastic leukemia mercaptopurine intolerance is associated with NUDT15 variants. Pediatric research 2020 Mar . Wang Der-Shiun, Yu Chih-Hsiang, Lin Chien-Yu, Chang Ya-Hsuan, Lin Kai-Hsin, Lin Dong-Tsamn, Jou Shiann-Tarng, Lu Meng-Yao, Chang Hsiu-Hao, Lin Shu-Wha, Chen Hsuan-Yu, Yang Yung- |
Predictive Value of NUDT15 Variants on Neutropenia Among Han Chinese Patients with Dermatologic Diseases: A Single-Center Observational Study. Dermatology and therapy 2020 Feb . Huang Po-Wei, Tseng Yu-Hsian, Tsai Tsen-Fa |
TPMT*3C as a Predictor of 6-Mercaptopurine-Induced Myelotoxicity in Thai Children with Acute Lymphoblastic Leukemia. Journal of personalized medicine 2021 8 11 (8): . Jantararoungtong Thawinee, Wiwattanakul Supaporn, Tiyasirichokchai Rawiporn, Prommas Santirhat, Sukprasong Rattanaporn, Koomdee Napatrupron, Jinda Pimonpan, Rachanakul Jiratha, Nuntharadthanaphong Nutthan, Pakakasama Samart, Anurathapan Usanarat, Hongeng Suradej, Sukasem Chonlaph |
The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia. Children (Basel, Switzerland) 2021 4 8 (3): . Lee Jae Min, Shim Ye Jee, Kim Do-Hoon, Jung Nani, Ha Jung-So |
Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis. Scientific reports 2021 Apr 11 (1): 7984. Miao Qiang, Yan Lin, Zhou Yanhong, Li Yi, Zou Yuangao, Wang Lanlan, Bai Yangjuan, Zhang Junlo |
NUDT15 c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmacogenomics and personalized medicine 2021 10 14 1303-1313. Pai Aswin Anand, Mohan Ajith, Benjamin Esther Sathya Bama, Illangeswaran Raveen Stephen Stallon, Xavier Raj Infencia, Janet Nancy Beryl, Arunachalam Arun Kumar, Kavitha M L, Kulkarni Uday, Devasia Anup J, Fouzia N A, Abraham Aby, Srivastava Alok, George Biju, Mathews Vikram, Korula Anu, Balasubramanian Poonkuzha |
Effect of ITPA Polymorphism on Adverse Drug Reactions of 6-Mercaptopurine in Pediatric Patients with Acute Lymphoblastic Leukemia: A Systematic Review and Meta-Analysis. Pharmaceuticals (Basel, Switzerland) 2022 4 15 (4): . Lee Yeonhong, Jang Eun Jeong, Yoon Ha-Young, Yee Jeong, Gwak Hye-S |
Inosine Triphosphate Pyrophosphatase and NUDT15 are Good Predictors of Clinical Outcomes in Thiopurine-Treated Chinese Patients with Inflammatory Bowel Disease. Therapeutic drug monitoring 2022 Jan . Luo Xuemei, Yan Simin, Jin Lu, Zhu Huaijun, Zhang Xiaoqi, Ge Weiho |
Association of ITPA gene polymorphisms with adverse effects of AZA/6-MP administration: a systematic review and meta-analysis. The pharmacogenomics journal 2022 1 22 (1): 39-54. Barba Evaggelia, Kontou Panagiota I, Michalopoulos Ioannis, Bagos Pantelis G, Braliou Georgia |
NUDT15 is a key genetic factor for prediction of hematotoxicity in pediatric patients who received a standard low dosage regimen of 6-mercaptopurine. Drug metabolism and pharmacokinetics 2022 1 43 100436. Khaeso Kanyarat, Komvilaisak Patcharee, Chainansamit Su-On, Nakkam Nontaya, Suwannaying Kunanya, Kuwatjanakul Pitchayanan, Hikino Keiko, Dornsena Areerat, Kanjanawart Sirimas, Laoaroon Napat, Vannaprasaht Suda, Taketani Takeshi, Tassaneeyakul Wichitt |
Genetic variants of genes involved in thiopurine metabolism pathway are associated with 6-mercaptopurine toxicity in pediatric acute lymphoblastic leukemia patients from Ethiopia. Frontiers in pharmacology 2023 5 14 1159307. Awol Mekonnen Ali, Haileyesus Adam, Daniel Hailu, Ephrem Engidawork, Rawleigh Howe, Teferra Abula, Marieke J H Coen |
ITPA Polymorphisms and the Incidence of Toxicities in Children with Acute Lymphoblastic Leukemia. Mediterranean journal of hematology and infectious diseases 2023 3 15 (1): e2023024. Svasdisant Patpetra, Glomglao Waraporn, Siraprapapat Preeyanun, Inthararujikul Wiyakan, Tachavanich Kalaya, Boonthimat Chetsada, Ardsiri Sakkarin, Chansing Kochpinchon, Sriprach Suwimon, Tongsai Sasima, Sinlapamongkolkul Phakatip, Sanpakit Kleebsabai, Buaboonnam Jassa |
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