HuGE Literature Finder
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Genome-wide association study of letrozole plasma concentrations identifies non-exonic variants that may affect CYP2A6 metabolic activity. Pharmacogenetics and genomics 2021 Jul 31 (5): 116-123. Hertz Daniel L, Douglas Julie A, Kidwell Kelley M, Gersch Christina L, Desta Zeruesenay, Storniolo Ana-Maria, Stearns Vered, Skaar Todd C, Hayes Daniel F, Henry N Lynn, Rae James |
UGT2B10 Genotype Influences Serum Cotinine Levels and Is a Primary Determinant of Higher Cotinine in African American Smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020 Jun . Sipe Christopher J, Koopmeiners Joseph S, Donny Eric C, Hatsukami Dorothy K, Murphy Sharon |
Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study. BMC cancer 2020 Mar 20 (1): 186. Abudushataer Maidina, Sato Noriko, Mieno Makiko, Sawabe Motoji, Muramatsu Masaaki, Arai Tom |
HapMap-based study: CYP2A13 may be a potential key metabolic enzyme gene in the carcinogenesis of lung cancer in non-smokers. Thoracic cancer 2019 Feb . Hua Feng, Guo Yonglu, Sun Qiang, Yang Leizhou, Gao Fa |
Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2019 Feb 28 (2): 311-320. Perez-Paramo Yadira X, Chen Gang, Ashmore Joseph H, Watson Christy J W, Nasrin Shamema, Adams-Haduch Jennifer, Wang Renwei, Gao Yu-Tang, Koh Woon-Puay, Yuan Jian-Min, Lazarus Phil |
Genetic Polymorphism of CYP2A6 and Its Relationship with Nicotine Metabolism in Male Bataknese Smokers Suffered from Lung Cancer in Indonesia. Open access Macedonian journal of medical sciences 2018 Jul 6 (7): 1199-1205. Soeroso Noni Novisari, Zain-Hamid Rozaimah, Sinaga Bintang Y M, Sadewa Ahmad Hamim, Syafiuddin Tamsil, Syahruddin Elisna, Tann Gino, Mutiara Er |
[The influence of CYP2A6 polymorphism on adjuvant S-1 chemotherapy outcomes in patients with curatively resected gastric cancer]. Zhonghua yi xue za zhi 2018 Jun 98 (24): 1915-1918. Hu F K, Shen J, Gao S |
Genome-wide association study of familial lung cancer.
![]() Carcinogenesis 2018 Jun . Byun Jinyoung, Schwartz Ann G, Lusk Christine, Wenzlaff Angela S, de Andrade Mariza, Mandal Diptasri, Gaba Colette, Yang Ping, You Ming, Kupert Elena Y, Anderson Marshall W, Han Younghun, Li Yafang, Qian David, Stilp Adrienne, Laurie Cathy, Nelson Sarah, Zheng Wenying, Hung Rayjean J, Gaborieau Valerie, Mckay James, Brennan Paul, Caporaso Neil E, Landi Maria Teresa, Wu Xifeng, McLaughlin John R, Brhane Yonathan, Bossé Yohan, Pinney Susan M, Bailey-Wilson Joan E, Amos Christopher |
Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population. BMC cancer 2018 May 18 (1): 525. Ezzeldin Nada, El-Lebedy Dalia, Darwish Amira, El Bastawisy Ahmed, Abd Elaziz Shereen Hamdy, Hassan Mirhane Mohamed, Saad-Hussein Am |
A randomized phase II study of S-1 versus capecitabine as first-line chemotherapy in elderly metastatic gastric cancer patients with or without poor performance status: clinical and pharmacogenetic results. Pharmacogenetics and genomics 2017 Nov . Kim Mi-Jung, Kong Sun-Young, Nam Byung-Ho, Kim Sohee, Park Young-Iee, Park Sook Ry |
CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients. Genomics, proteomics & bioinformatics 2017 Aug . Yang Lin, Zou Shanshan, Shu Chang, Song Yan, Sun Yong-Kun, Zhang Wen, Zhou Aiping, Yuan Xinghua, Yang Yi, Hu Songni |
A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis. Radiation oncology (London, England) 2017 Mar 12 (1): 62. Kim Sun Young, Baek Ji Yeon, Oh Jae Hwan, Park Sung Chan, Sohn Dae Kyung, Kim Min Ju, Chang Hee Jin, Kong Sun-Young, Kim Dae Yo |
Low Cotinine Glucuronidation Results in Higher Serum and Saliva Cotinine in African American Compared to White Smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Mar . Murphy Sharon E, Sipe Christopher J, Choi Kwangsoo, Raddatz Leah M, Koopmeiners Joseph S, Donny Eric C, Hatsukami Dorothy |
CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study. Carcinogenesis 2017 Feb . Yuan Jian-Min, Nelson Heather H, Carmella Steven G, Wang Renwei, Kuriger-Laber Jacquelyn, Jin Aizhen, Adams-Haduch Jennifer, Hecht Stephen S, Koh Woon-Puay, Murphy Sharon |
Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer. Pharmacogenetics and genomics 2017 Feb . Tanner Julie-Anne, Henderson Jeffrey A, Buchwald Dedra, Howard Barbara V, Nez Henderson Patricia, Tyndale Rachel |
Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6. Chemical research in toxicology 2017 Jan 30 (1): 410-419. Murphy Sharon |
Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway. Cancer chemotherapy and pharmacology 2017 Jan 79 (1): 69-79. He Ming-Ming, Zhang Dong-Sheng, Wang Feng, Wang Zi-Xian, Yuan Shu-Qiang, Wang Zhi-Qiang, Luo Hui-Yan, Ren Chao, Qiu Miao-Zhen, Jin Ying, Wang De-Shen, Chen Dong-Liang, Zeng Zhao-Lei, Li Yu-Hong, He Yang-Yang, Hao Yuan-Tao, Guo Pi, Wang Feng-Hua, Zeng Yi-Xin, Xu Rui-H |
Effect of Genetic Polymorphisms and Long-Term Tobacco Exposure on the Risk of Breast Cancer. International journal of molecular sciences 2016 Oct 17 (10): . Verde Zoraida, Santiago Catalina, Chicharro Luis Miguel, Reinoso-Barbero Luis, Tejerina Alejandro, Bandrés Fernando, Gómez-Gallego Fél |
Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.
![]() Cancer research 2016 Oct 76 (19): 5768-5776. Patel Yesha M, Park Sunghim L, Han Younghun, Wilkens Lynne R, Bickeböller Heike, Rosenberger Albert, Caporaso Neil, Landi Maria Teresa, Brüske Irene, Risch Angela, Wei Yongyue, Christiani David C, Brennan Paul, Houlston Richard, McKay James, McLaughlin John, Hung Rayjean, Murphy Sharon, Stram Daniel O, Amos Christopher, Le Marchand Lo |
Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity. Carcinogenesis 2016 Mar 37 (3): 269-279. Park Sungshim L, Tiirikainen Maarit I, Patel Yesha M, Wilkens Lynne R, Stram Daniel O, Le Marchand Loic, Murphy Sharon |
Genetic Polymorphisms of CYP2A6 in a Case-Control Study on Bladder Cancer in Japanese Smokers. Biological & pharmaceutical bulletin 2016 39 (1): 84-9. Kumondai Masaki, Hosono Hiroki, Orikasa Kazuhiko, Arai Yoichi, Arai Tomio, Sugimura Haruhiko, Ozono Seiichiro, Sugiyama Takayuki, Takayama Tatsuya, Sasaki Takamitsu, Hirasawa Noriyasu, Hiratsuka Masahi |
Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. Gastroenterology 2016 05 150 (5): 1171-1182. Sawada Genta, Niida Atsushi, Uchi Ryutaro, Hirata Hidenari, Shimamura Teppei, Suzuki Yutaka, Shiraishi Yuichi, Chiba Kenichi, Imoto Seiya, Takahashi Yusuke, Iwaya Takeshi, Sudo Tomoya, Hayashi Tomoatsu, Takai Hiroki, Kawasaki Yoshihiro, Matsukawa Takashi, Eguchi Hidetoshi, Sugimachi Keishi, Tanaka Fumiaki, Suzuki Hiromichi, Yamamoto Ken, Ishii Hideshi, Shimizu Makiko, Yamazaki Hiroshi, Yamazaki Makoto, Tachimori Yuji, Kajiyama Yoshiaki, Natsugoe Shoji, Fujita Hiromasa, Mafune Kenichi, Tanaka Yoichi, Kelsell David P, Scott Claire A, Tsuji Shoji, Yachida Shinichi, Shibata Tatsuhiro, Sugano Sumio, Doki Yuichiro, Akiyama Tetsu, Aburatani Hiroyuki, Ogawa Seishi, Miyano Satoru, Mori Masaki, Mimori Kos |
A germline predictive signature of response to platinum chemotherapy in esophageal cancer. Translational research : the journal of laboratory and clinical medicine 2015 Dec . Rumiato Enrica, Boldrin Elisa, Malacrida Sandro, Battaglia Giorgio, Bocus Paolo, Castoro Carlo, Cagol Matteo, Chiarion-Sileni Vanna, Ruol Alberto, Amadori Alberto, Saggioro Danie |
Associations between CYP2A6 polymorphisms and outcomes of adjuvant S-1 chemotherapy in patients with curatively resected gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Dec . Jeong Jae Ho, Park Sook Ryun, Ahn Yongchel, Ryu Min-Hee, Ryoo Baek-Yeol, Kong Sun-Young, Yook Jeong Hwan, Yoo Moon-Won, Kim Beom Su, Kim Byung Sik, Kang Yoon-K |
Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study. International journal of cancer. Journal international du cancer 2015 Dec . Yuan Jian-Min, Nelson Heather H, Butler Lesley M, Carmella Steven G, Wang Renwei, Kuriger-Laber Jacquelyn K, Adams-Haduch Jennifer, Hecht Stephen S, Gao Yu-Tang, Murphy Sharon |
CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers. Drug metabolism and pharmacokinetics 2015 Aug 30 (4): 263-8. Hosono Hiroki, Kumondai Masaki, Arai Tomio, Sugimura Haruhiko, Sasaki Takamitsu, Hirasawa Noriyasu, Hiratsuka Masahi |
The allele frequency of CYP2A6*4 in four ethnic groups of China. Experimental and molecular pathology 2015 Jun 98 (3): 546-8. Pang Cong, Liu Jin-Hui, Xu Yi-Song, Chen Chao, Dai Peng-G |
A phase II study of perioperative S-1 combined with weekly docetaxel in patients with locally advanced gastric carcinoma: clinical outcomes and clinicopathological and pharmacogenetic predictors for survival. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2015 Apr . Kim Young-Woo, Kim Mi-Jung, Ryu Keun Won, Lim Hyeong-Seok, Lee Jun Ho, Kong Sun-Young, Lee Jong Seok, Choi Il Ju, Kim Chan Gyoo, Lee Jong Yeul, Cho Soo-Jeong, Kook Myeong-Cherl, Park Young-Iee, Kim Seok-Ki, Park Sook Ry |
Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PloS one 2015 10 (7): e0126113. Bergen Andrew W, Michel Martha, Nishita Denise, Krasnow Ruth, Javitz Harold S, Conneely Karen N, Lessov-Schlaggar Christina N, Hops Hyman, Zhu Andy Z X, Baurley James W, McClure Jennifer B, Hall Sharon M, Baker Timothy B, Conti David V, Benowitz Neal L, Lerman Caryn, Tyndale Rachel F, Swan Gary E, |
Role of Metabolic Enzymes P450 (CYP) on Activating Procarcinogen and their Polymorphisms on the Risk of Cancers. Current drug metabolism 2015 16 (10): 850-63. He Xin, Feng Sh |
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- Page last updated:May 26, 2022
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