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Effects of genetic polymorphisms on methotrexate levels and toxicity in Chinese patients with acute lymphoblastic leukemia. Blood science (Baltimore, Md.) 2023 2 5 (1): 32-38. Hao Qishan, Song Yang, Fang Qiuyun, Lin Yani, Chen Long, Wang Xiaodan, Zhang Ping, Wang Zhe, Gong Xiaoyuan, Liu Kaiqi, Li Qinghua, Tian Zheng, Wang Min, Wang Jianxiang, Mi Yingcha |
Novel and replicated clinical and genetic risk factors for toxicity from high-dose methotrexate in pediatric acute lymphoblastic leukemia. Pharmacotherapy 2023 2 43 (3): 205-214. Zobeck Mark, Bernhardt M Brooke, Kamdar Kala Y, Rabin Karen R, Lupo Philip J, Scheurer Michael |
Evaluation of cytogenetic and molecular markers with MTX-mediated toxicity in pediatric acute lymphoblastic leukemia patients. Cancer chemotherapy and pharmacology 2022 Mar 89 (3): 393-400. Ramalingam Ravi, Kaur Harpreet, Scott Julius Xavier, Sneha Latha M, Arunkumar Ganeshprasad, Srinivasan Arathi, Paul Solomon F |
[A Case-Control Study on Receptor Gene Polymorphism and Risk Suffering from Adult Acute Leukemia in Fujian Area]. Zhongguo shi yan xue ye xue za zhi 2021 Feb 29 (1): 1-8. Zhang Feng, Fu Hai-Ying, Zhou Hua-Rong, Chen Rong, Shen Jian-Zh |
AHR-dependent genes and response to MTX therapy in rheumatoid arthritis patients. The pharmacogenomics journal 2021 7 21 (5): 608-621. Wajda Anna, Walczuk Ewa, Stypi?ska Barbara, Lach Jakub, Yermakovich Danat, Sivitskaya Larysa, Romanowska-Próchnicka Katarzyna, Wysocki Tomasz, Jaro?czyk Ma?gorzata, Paradowska-Gorycka Agniesz |
Pharmacogenetic evaluation of 6-mercaptopurine-mediated toxicity in pediatric acute lymphoblastic leukemia patients from a South Indian population. Pharmacogenomics 2021 4 22 (7): 401-411. Ramalingam Ravi, Kaur Harpreet, Scott Julius Xavier, Sneha Latha M, Arun Kumar Ganesh Prasad, Srinivasan Arathi, Paul Solomon |
Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia. Iranian journal of basic medical sciences 2020 Jun 23 (6): 800-809. Esmaili Mohammad Ali, Kazemi Ahmad, Faranoush Mohammad, Mellstedt Hakan, Zaker Farhad, Safa Majid, Mehrvar Narjes, Rezvany Mohammad Re |
Pharmacogenomic Markers of Methotrexate Response in the Consolidation Phase of Pediatric Acute Lymphoblastic Leukemia Treatment. Genes 2020 Apr 11 (4): . Kotur Nikola, Lazic Jelena, Ristivojevic Bojan, Stankovic Biljana, Gasic Vladimir, Dokmanovic Lidija, Krstovski Nada, Milosevic Goran, Janic Dragana, Zukic Branka, Pavlovic Son |
Polymorphisms of SLC19A1 80 G>A, MTHFR 677 C>T, and Tandem TS Repeats Influence Pharmacokinetics, Acute Liver Toxicity, and Vomiting in Children With Acute Lymphoblastic Leukemia Treated With High Doses of Methotrexate. Frontiers in pediatrics 2020 8 307. Cwiklinska Magdalena, Czogala Malgorzata, Kwiecinska Kinga, Madetko-Talowska Anna, Szafarz Malgorzata, Pawinska Katarzyna, Wieczorek Aleksandra, Klekawka Tomasz, Rej Magdalena, Stepien Konrad, Halubiec Przemyslaw, Lazarczyk Agnieszka, Miklusiak Karol, Bik-Multanowski Miroslaw, Balwierz Walentyna, Skoczen Szym |
[Multiplex Genotyping of Allelic Variants of Genes Involved in Metabolizing Antileukemic Drugs]. Molekuliarnaia biologiia 2018 4 52 (2): 238-245. Fesenko D O, Avdonina M A, Gukasyan L G, Surzhikov S A, Chudinov A V, Zasedatelev A S, Nasedkina T |
Methotrexate pharmacogenetics in Uruguayan adults with hematological malignant diseases. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Sep 109 480-485. Giletti Andrea, Vital Marcelo, Lorenzo Mariana, Cardozo Patricia, Borelli Gabriel, Gabus Raúl, Martínez Lem, Díaz Lilian, Assar Rodrigo, Rodriguez María Noel, Esperón Patric |
MiR-pharmacogenetics of methotrexate in childhood B-cell acute lymphoblastic leukemia. Pharmacogenetics and genomics 2016 Sep . Iparraguirre Leire, Gutierrez-Camino Angela, Umerez Maitane, Martin-Guerrero Idoia, Astigarraga Itziar, Navajas Aurora, Sastre Ana, Garcia de Andoin Nagore, Garcia-Orad Afri |
Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis. Molecular carcinogenesis 2016 Mar . Gonçalves Ana Cristina, Alves Raquel, Baldeiras Inês, Cortesão Emília, Carda José Pedro, Branco Claudia C, Oliveiros Bárbara, Loureiro Luísa, Pereira Amélia, Nascimento Costa José Manuel, Sarmento-Ribeiro Ana Bela, Mota-Vieira Lui |
Genetic Polymorphisms Associated to Folate Transport as Predictors of Increased Risk for Acute Lymphoblastic Leukemia in Mexican Children. Frontiers in pharmacology 2016 7 238. Zaruma-Torres Fausto, Lares-Asseff Ismael, Lima Aurea, Reyes-Espinoza Aarón, Loera-Castañeda Verónica, Sosa-Macías Martha, Galaviz-Hernández Carlos, Arias-Peláez María C, Reyes-López Miguel A, Quiñones Luis |
Copy number variability analysis of pharmacogenes in patients with lymphoma, leukemia, hepatocellular, and lung carcinoma using The Cancer Genome Atlas data. Pharmacogenetics and genomics 2015 Jan 25 (1): 1-7. Kim In-Wha, Han Nayoung, Kim Myeong Gyu, Kim Therasa, Oh Jung |
Effect of polymorphisms within methotrexate pathway genes on methotrexate toxicity and plasma levels in adults with hematological malignancies. Pharmacogenomics 2014 Aug 15 (11): 1479-94. Suthandiram Sujatha, Gan Gin-Gin, Zain Shamsul Mohd, Bee Ping-Chong, Lian Lay-Hoong, Chang Kian-Meng, Ong Tee-Chuan, Mohamed Zahur |
Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. Pharmacogenetics and genomics 2014 Aug 24 (8): 387-96. Zgheib Nathalie K, Akra-Ismail Maya, Aridi Carol, Mahfouz Rami, Abboud Miguel R, Solh Hassan, Muwakkit Samar |
Effects of a microRNA binding site polymorphism in SLC19A1 on methotrexate concentrations in Chinese children with acute lymphoblastic leukemia. Medical oncology (Northwood, London, England) 2014 Jul 31 (7): 62. Wang Shu-mei, Sun Lu-lu, Zeng Wei-xin, Wu Wan-shui, Zhang Guo-lia |
Influence of pre-hydration and pharmacogenetics on plasma methotrexate concentration and renal dysfunction following high-dose methotrexate therapy. International journal of hematology 2013 Dec 98 (6): 702-7. Yanagimachi Masakatsu, Goto Hiroaki, Kaneko Tetsuji, Naruto Takuya, Sasaki Koji, Takeuchi Masanobu, Tanoshima Reo, Kato Hiromi, Yokosuka Tomoko, Kajiwara Ryosuke, Fujii Hisaki, Tanaka Fumiko, Goto Shoko, Takahashi Hiroyuki, Mori Masaaki, Kai Sumio, Yokota Shump |
Polymorphisms in the methotrexate transport pathway: a new tool for MTX plasma level prediction in pediatric acute lymphoblastic leukemia. Pharmacogenetics and genomics 2013 Feb 23 (2): 53-61. Lopez-Lopez Elixabet, Ballesteros Javier, Piñan Maria A, Sanchez de Toledo José, Garcia de Andoin Nagore, Garcia-Miguel Purificacion, Navajas Aurora, Garcia-Orad Afri |
Using a Bayesian hierarchical model for identifying single nucleotide polymorphisms associated with childhood acute lymphoblastic leukemia risk in case-parent triads. PloS one 2013 8 (12): e84658. Cao Ying, Lupo Philip J, Swartz Michael D, Nousome Darryl, Scheurer Michael |
Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia. Cancer causes & control : CCC 2011 Sep 22 (9): 1243-58. Metayer Catherine, Scélo Ghislaine, Chokkalingam Anand P, Barcellos Lisa F, Aldrich Melinda C, Chang Jeffrey S, Guha Neela, Urayama Kevin Y, Hansen Helen M, Block Gladys, Kiley Vincent, Wiencke John K, Wiemels Joseph L, Buffler Patricia |
The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number. Blood 2010 Jun 115 (23): 4671-7. Gregers Jannie, Christensen Ib Jarle, Dalhoff Kim, Lausen Birgitte, Schroeder Henrik, Rosthoej Steen, Carlsen Niels, Schmiegelow Kjeld, Peterson Cu |
Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group. Leukemia research 2010 Mar 34 (3): 276-83. Yeoh Allen Eng-Juh, Lu Yi, Chan Jason Yong-Sheng, Chan Yiong Huak, Ariffin Hany, Kham Shirley Kow-Yin, Quah Thuan Cho |
Associations between genetic variants in folate and drug metabolizing pathways and relapse risk in pediatric acute lymphoid leukemia on CCG-1952. Leukemia research reports 0 4 (2): 47-50. Vujkovic Marijana, Kershenbaum Aaron, Wray Lisa, McWilliams Thomas, Cannon Shannon, Devidas Meenakshi, Stork Linda, Aplenc Richa |
Influence of variants in folate metabolism genes on 6-mercaptopurine induced toxicity during treatment for childhood acute lymphocytic leukemia. Journal of B.U.ON. : official journal of the Balkan Union of Oncology 0 24 (5): 2075-2083. Milosevic Goran, Kotur Nikola, Lazic Jelena, Krstovski Nada, Stankovic Biljana, Zukic Branka, Janic Dragana, Jurisic Vladimir, Pavlovic Sonja, Dokmanovic Lidi |
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- Page last updated:Mar 22, 2023
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