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Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.
European heart journal 2022 3 43 (17): 1668-1680. Roselli Carolina, Yu Mengyao, Nauffal Victor, Georges Adrien, Yang Qiong, Love Katie, Weng Lu-Chen, Delling Francesca N, Maurya Svetlana R, Schrölkamp Maren, Tfelt-Hansen Jacob, Hagège Albert, Jeunemaitre Xavier, Debette Stéphanie, Amouyel Philippe, Guan Wyliena, Muehlschlegel Jochen D, Body Simon C, Shah Svati, Samad Zainab, Kyryachenko Sergiy, Haynes Carol, Rienstra Michiel, Le Tourneau Thierry, Probst Vincent, Roussel Ronan, Wijdh-Den Hamer Inez J, Siland Joylene E, Knowlton Kirk U, Jacques Schott Jean, Levine Robert A, Benjamin Emelia J, Vasan Ramachandran S, Horne Benjamin D, Muhlestein Joseph B, Benfari Giovanni, Enriquez-Sarano Maurice, Natale Andrea, Mohanty Sanghamitra, Trivedi Chintan, Shoemaker Moore B, Yoneda Zachary T, Wells Quinn S, Baker Michael T, Farber-Eger Eric, Michelena Hector I, Lundby Alicia, Norris Russell A, Slaugenhaupt Susan A, Dina Christian, Lubitz Steven A, Bouatia-Naji Nabila, Ellinor Patrick T, Milan David |
| Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study.
JAMA cardiology 2021 Jun . Machipisa Tafadzwa, Chong Michael, Muhamed Babu, Chishala Chishala, Shaboodien Gasnat, Pandie Shahiemah, de Vries Jantina, Laing Nakita, Joachim Alexia, Daniels Rezeen, Ntsekhe Mpiko, Hugo-Hamman Christopher T, Gitura Bernard, Ogendo Stephen, Lwabi Peter, Okello Emmy, Damasceno Albertino, Novela Celia, Mocumbi Ana O, Madeira Goeffrey, Musuku John, Mtaja Agnes, ElSayed Ahmed, Elhassan Huda H M, Bode-Thomas Fidelia, Okeahialam Basil N, Zühlke Liesl J, Mulder Nicola, Ramesar Raj, Lesosky Maia, Parks Tom, Cordell Heather J, Keavney Bernard, Engel Mark E, Paré Guillau |
| Genome-wide association study of cardiac troponin I in the general population.
Human molecular genetics 2021 . Moksnes Marta R, Røsjø Helge, Richmond Anne, Lyngbakken Magnus N, Graham Sarah E, Hansen Ailin Falkmo, Wolford Brooke N, Gagliano Taliun Sarah A, LeFaive Jonathon, Rasheed Humaira, Thomas Laurent F, Zhou Wei, Aung Nay, Surakka Ida, Douville Nicholas J, Campbell Archie, Porteous David J, Petersen Steffen E, Munroe Patricia B, Welsh Paul, Sattar Naveed, Smith George Davey, Fritsche Lars G, Nielsen Jonas B, Åsvold Bjørn Olav, Hveem Kristian, Hayward Caroline, Willer Cristen J, Brumpton Ben M, Omland Torbjø |
| Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Hypertension (Dallas, Tex. : 1979) 2021 Feb 77 (2): 383-392. Gill Dipender, Cameron Alan C, Burgess Stephen, Li Xue, Doherty Daniel J, Karhunen Ville, Abdul-Rahim Azmil H, Taylor-Rowan Martin, Zuber Verena, Tsao Philip S, Klarin Derek, , Evangelou Evangelos, Elliott Paul, Damrauer Scott M, Quinn Terence J, Dehghan Abbas, Theodoratou Evropi, Dawson Jesse, Tzoulaki Ioan |
| Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.
Nature communications 2021 5 12 (1): 2579. Pazoki Raha, Vujkovic Marijana, Elliott Joshua, Evangelou Evangelos, Gill Dipender, Ghanbari Mohsen, van der Most Peter J, Pinto Rui Climaco, Wielscher Matthias, Farlik Matthias, Zuber Verena, de Knegt Robert J, Snieder Harold, Uitterlinden André G, , Lynch Julie A, Jiang Xiyun, Said Saredo, Kaplan David E, Lee Kyung Min, Serper Marina, Carr Rotonya M, Tsao Philip S, Atkinson Stephen R, Dehghan Abbas, Tzoulaki Ioanna, Ikram M Arfan, Herzig Karl-Heinz, Järvelin Marjo-Riitta, Alizadeh Behrooz Z, O'Donnell Christopher J, Saleheen Danish, Voight Benjamin F, Chang Kyong-Mi, Thursz Mark R, Elliott Paul, |
| Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease.
Diabetes 2021 5 70 (8): 1843-1856. Martin Susan, Cule Madeleine, Basty Nicolas, Tyrrell Jessica, Beaumont Robin N, Wood Andrew R, Frayling Timothy M, Sorokin Elena, Whitcher Brandon, Liu Yi, Bell Jimmy D, Thomas E Louise, Yaghootkar Hani |
| Genome-Wide Identification of Rare and Common Variants Driving Triglyceride Levels in a Nevada Population.
Frontiers in genetics 2021 3 12 639418. Read Robert W, Schlauch Karen A, Lombardi Vincent C, Cirulli Elizabeth T, Washington Nicole L, Lu James T, Grzymski Joseph |
| Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation.
Circulation. Genomic and precision medicine 2021 11 14 (6): e003460. Yang Yunju, Bartz Traci M, Brown Michael R, Guo Xiuqing, Zilhão Nuno R, Trompet Stella, Weiss Stefan, Yao Jie, Brody Jennifer A, Defilippi Christopher R, Hoogeveen Ron C, Lin Henry J, Gudnason Vilmundur, Ballantyne Christie M, Dörr Marcus, Jukema J Wouter, Petersmann Astrid, Psaty Bruce M, Rotter Jerome I, Boerwinkle Eric, Fornage Myriam, Jun Goo, Yu Bi |
| Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.
Circulation. Genomic and precision medicine 2021 10 14 (6): e003421. Olson Nels C, Raffield Laura M, Moxley Anne H, Miller-Fleming Tyne W, Auer Paul L, Franceschini Nora, Ngo Debby, Thornton Timothy A, Lange Ethan M, Li Yun, Nickerson Deborah A, Zakai Neil A, Gerszten Robert E, Cox Nancy J, Correa Adolfo, Mohlke Karen L, Reiner Alexander |
| Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.
Journal of human genetics 2021 1 66 (6): 625-636. Crawford Andrew A, Bankier Sean, Altmaier Elisabeth, Barnes Catriona L K, Clark David W, Ermel Raili, Friedrich Nele, van der Harst Pim, Joshi Peter K, Karhunen Ville, Lahti Jari, Mahajan Anubha, Mangino Massimo, Nethander Maria, Neumann Alexander, Pietzner Maik, Sukhavasi Katyayani, Wang Carol A, Bakker Stephan J L, Bjorkegren Johan L M, Campbell Harry, Eriksson Johan, Gieger Christian, Hayward Caroline, Jarvelin Marjo-Riitta, McLachlan Stela, Morris Andrew P, Ohlsson Claes, Pennell Craig E, Price Jackie, Rudan Igor, Ruusalepp Arno, Spector Tim, Tiemeier Henning, Völzke Henry, Wilson James F, Michoel Tom, Timpson Nicolas J, Smith George Davey, Walker Brian R, |
| Congenital heart disease risk loci identified by genome-wide association study in European patients.
The Journal of clinical investigation 2020 Nov . Lahm Harald, Jia Meiwen, Dreßen Martina, Wirth Felix F M, Puluca Nazan, Gilsbach Ralf, Keavney Bernard, Cleuziou Julie, Beck Nicole, Bondareva Olga, Dzilic Elda, Burri Melchior, König Karl C, Ziegelmüller Johannes A, Abou-Ajram Claudia, Neb Irina, Zhang Zhong, Doppler Stefanie A, Mastantuono Elisa, Lichtner Peter, Eckstein Gertrud, Hörer Jürgen, Ewert Peter, Priest James R, Hein Lutz, Lange Rüdiger, Meitinger Thomas, Cordell Heather J, Müller-Myhsok Bertram, Krane Mark |
| Association of an IGHV3-66 gene variant with Kawasaki disease.
Journal of human genetics 2020 Oct . Johnson Todd A, Mashimo Yoichi, Wu Jer-Yuarn, Yoon Dankyu, Hata Akira, Kubo Michiaki, Takahashi Atsushi, Tsunoda Tatsuhiko, Ozaki Kouichi, Tanaka Toshihiro, Ito Kaoru, Suzuki Hiroyuki, Hamada Hiromichi, Kobayashi Tohru, Hara Toshiro, Chen Chien-Hsiun, Lee Yi-Ching, Liu Yi-Min, Chang Li-Ching, Chang Chun-Ping, Hong Young-Mi, Jang Gi-Young, Yun Sin-Weon, Yu Jeong-Jin, Lee Kyung-Yil, Kim Jae-Jung, Park Taesung, , Lee Jong-Keuk, Chen Yuan-Tsong, Onouchi Yoshihi |
| Genetic Basis and Prognostic Value of Exercise QT Dynamics.
Circulation. Genomic and precision medicine 2020 Aug 13 (4): e002774. van Duijvenboden Stefan, Ramírez Julia, Young William J, Mifsud Borbala, Orini Michele, Tinker Andrew, Munroe Patricia B, Lambiase Pier |
| Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.
Nature genetics 2020 Jun . Vujkovic Marijana, Keaton Jacob M, Lynch Julie A, Miller Donald R, Zhou Jin, Tcheandjieu Catherine, Huffman Jennifer E, Assimes Themistocles L, Lorenz Kimberly, Zhu Xiang, Hilliard Austin T, Judy Renae L, Huang Jie, Lee Kyung M, Klarin Derek, Pyarajan Saiju, Danesh John, Melander Olle, Rasheed Asif, Mallick Nadeem H, Hameed Shahid, Qureshi Irshad H, Afzal Muhammad Naeem, Malik Uzma, Jalal Anjum, Abbas Shahid, Sheng Xin, Gao Long, Kaestner Klaus H, Susztak Katalin, Sun Yan V, DuVall Scott L, Cho Kelly, Lee Jennifer S, Gaziano J Michael, Phillips Lawrence S, Meigs James B, Reaven Peter D, Wilson Peter W, Edwards Todd L, Rader Daniel J, Damrauer Scott M, O'Donnell Christopher J, Tsao Philip S, , , , Chang Kyong-Mi, Voight Benjamin F, Saleheen Dani |
| The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans.
Scientific reports 2020 Jun 10 (1): 9004. Auckland Kathryn, Mittal Balraj, Cairns Benjamin J, Garg Naveen, Kumar Surendra, Mentzer Alexander J, Kado Joseph, Perman Mai Ling, Steer Andrew C, Hill Adrian V S, Parks T |
| Genomic analysis of diet composition finds novel loci and associations with health and lifestyle.
Molecular psychiatry 2020 May . Meddens S Fleur W, de Vlaming Ronald, Bowers Peter, Burik Casper A P, Linnér Richard Karlsson, Lee Chanwook, Okbay Aysu, Turley Patrick, Rietveld Cornelius A, Fontana Mark Alan, Ghanbari Mohsen, Imamura Fumiaki, McMahon George, van der Most Peter J, Voortman Trudy, Wade Kaitlin H, Anderson Emma L, Braun Kim V E, Emmett Pauline M, Esko Tonu, Gonzalez Juan R, Kiefte-de Jong Jessica C, Langenberg Claudia, Luan Jian'an, Muka Taulant, Ring Susan, Rivadeneira Fernando, Snieder Harold, van Rooij Frank J A, Wolffenbuttel Bruce H R, , , , Smith George Davey, Franco Oscar H, Forouhi Nita G, Ikram M Arfan, Uitterlinden Andre G, van Vliet-Ostaptchouk Jana V, Wareham Nick J, Cesarini David, Harden K Paige, Lee James J, Benjamin Daniel J, Chow Carson C, Koellinger Philipp |
| Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.
PLoS medicine 2020 Mar 17 (3): e1003062. Richardson Tom G, Sanderson Eleanor, Palmer Tom M, Ala-Korpela Mika, Ference Brian A, Davey Smith George, Holmes Michael |
| Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank.
Arteriosclerosis, thrombosis, and vascular biology 2020 Feb 40 (2): 446-461. Strawbridge Rona J, Ward Joey, Bailey Mark E S, Cullen Breda, Ferguson Amy, Graham Nicholas, Johnston Keira J A, Lyall Laura M, Pearsall Robert, Pell Jill, Shaw Richard J, Tank Rachana, Lyall Donald M, Smith Daniel |
| A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos.
American journal of human genetics 2020 10 107 (5): 849-863. Feofanova Elena V, Chen Han, Dai Yulin, Jia Peilin, Grove Megan L, Morrison Alanna C, Qi Qibin, Daviglus Martha, Cai Jianwen, North Kari E, Laurie Cathy C, Kaplan Robert C, Boerwinkle Eric, Yu Bi |
| Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.
The European respiratory journal 2020 11 57 (5): . Strausz Satu, Ruotsalainen Sanni, Ollila Hanna M, Karjalainen Juha, Kiiskinen Tuomo, Reeve Mary, Kurki Mitja, Mars Nina, Havulinna Aki S, Luonsi Elina, Mansour Aly Dina, Ahlqvist Emma, Teder-Laving Maris, Palta Priit, Groop Leif, Mägi Reedik, Mäkitie Antti, Salomaa Veikko, Bachour Adel, Tuomi Tiinamaija, , Palotie Aarno, Palotie Tuula, Ripatti Samu |
| Genetic Architecture of Circulating Very-Long-Chain (C24:0 and C22:0) Ceramide Concentrations.
Journal of lipid and atherosclerosis 2020 9 (1): 172-183. Cresci Sharon, Zhang Ruibo, Yang Qiong, Duncan Meredith S, Xanthakis Vanessa, Jiang Xuntian, Vasan Ramachandran S, Schaffer Jean E, Peterson Linda |
| Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network.
Genetic epidemiology 2020 9 45 (1): 4-15. Palmer Melody R, Kim Daniel S, Crosslin David R, Stanaway Ian B, Rosenthal Elisabeth A, Carrell David S, Cronkite David J, Gordon Adam, Du Xiaomeng, Li Yatong K, Williams Marc S, Weng Chunhua, Feng Qiping, Li Rongling, Pendergrass Sarah A, Hakonarson Hakon, Fasel David, Sohn Sunghwan, Sleiman Patrick, Handelman Samuel K, Speliotes Elizabeth, Kullo Iftikhar J, Larson Eric B, , Jarvik Gail |
| The Assessment of Interleukin-18 on the Risk of Coronary Heart Disease.
Medicinal chemistry (Shariqah (United Arab Emirates)) 2019 Oct . Sun Weiju, Han Ying, Yang Shuo, Zhuang He, Zhang Jingwen, Cheng Liang, Fu |
| Cardiac Troponin T and Troponin I in the General Population.
Circulation 2019 Jun 139 (24): 2754-2764. Welsh Paul, Preiss David, Hayward Caroline, Shah Anoop S V, McAllister David, Briggs Andrew, Boachie Charles, McConnachie Alex, Padmanabhan Sandosh, Welsh Claire, Woodward Mark, Campbell Archie, Porteous David, Mills Nicholas L, Sattar Nave |
| Assessing the causal association of glycine with risk of cardio-metabolic diseases.
Nature communications 2019 03 10 (1): 1060. Wittemans Laura B L, Lotta Luca A, Oliver-Williams Clare, Stewart Isobel D, Surendran Praveen, Karthikeyan Savita, Day Felix R, Koulman Albert, Imamura Fumiaki, Zeng Lingyao, Erdmann Jeanette, Schunkert Heribert, Khaw Kay-Tee, Griffin Julian L, Forouhi Nita G, Scott Robert A, Wood Angela M, Burgess Stephen, Howson Joanna M M, Danesh John, Wareham Nicholas J, Butterworth Adam S, Langenberg Claud |
| Bilirubin and risk of ischemic heart disease in Korea: a two-sample Mendelian randomization study.
Epidemiology and health 2019 41 e2019034. Jeon Christina, Lee Ji-Young, Lee Sun Ju, Jung Keum Ji, Kimm Heejin, Jee Sun |
| Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.
Translational psychiatry 2019 02 9 (1): 14. Arnau-Soler Aleix, Macdonald-Dunlop Erin, Adams Mark J, Clarke Toni-Kim, MacIntyre Donald J, Milburn Keith, Navrady Lauren, , , Hayward Caroline, McIntosh Andrew M, Thomson Pippa |
| Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease.
Circulation. Genomic and precision medicine 2018 Dec 11 (12): e002239. Siewert Katherine M, Voight Benjamin |
| Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.
Scientific reports 2018 Apr 8 (1): 6451. Tikkanen Emmi, Gustafsson Stefan, Amar David, Shcherbina Anna, Waggott Daryl, Ashley Euan A, Ingelsson Er |
| Genome-wide analysis yields new loci associating with aortic valve stenosis.
Nature communications 2018 Mar 9 (1): 987. Helgadottir Anna, Thorleifsson Gudmar, Gretarsdottir Solveig, Stefansson Olafur A, Tragante Vinicius, Thorolfsdottir Rosa B, Jonsdottir Ingileif, Bjornsson Thorsteinn, Steinthorsdottir Valgerdur, Verweij Niek, Nielsen Jonas B, Zhou Wei, Folkersen Lasse, Martinsson Andreas, Heydarpour Mahyar, Prakash Siddharth, Oskarsson Gylfi, Gudbjartsson Tomas, Geirsson Arnar, Olafsson Isleifur, Sigurdsson Emil L, Almgren Peter, Melander Olle, Franco-Cereceda Anders, Hamsten Anders, Fritsche Lars, Lin Maoxuan, Yang Bo, Hornsby Whitney, Guo Dongchuan, Brummett Chad M, Abecasis Gonçalo, Mathis Michael, Milewicz Dianna, Body Simon C, Eriksson Per, Willer Cristen J, Hveem Kristian, Newton-Cheh Christopher, Smith J Gustav, Danielsen Ragnar, Thorgeirsson Gudmundur, Thorsteinsdottir Unnur, Gudbjartsson Daniel F, Holm Hilma, Stefansson Ka |
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- Page last updated:Jun 28, 2022
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