HuGE Literature Finder
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Records 1-29
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Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population.
Frontiers in pharmacology 2018 9 1390. Lv Shuang, Fan HuiZhen, Li Jiang, Yang Hui, Huang Jing, Shu XiaoMing, Zhang Lu, Xu Yuan, Li Xiaoya, Zuo Jieyu, Xiao Che |
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Risk factors for abnormal hepatic enzyme elevation by methotrexate treatment in patients with rheumatoid arthritis: a hospital based-cohort study.
Modern rheumatology 2017 Dec 1-27. Hakamata Jun, Hashiguchi Masayuki, Kaneko Yuko, Yamaoka Kunihiro, Shimizu Mikiko, Maruyama Junya, Takeuchi Tsutomu, Mochizuki Mayu |
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Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis.
Scientific reports 2017 Mar 7 44015. Qiu Qi, Huang Jing, Shu Xiaoming, Fan Huizheng, Zhou Youwen, Xiao Che |
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Are gene polymorphisms related to treatment outcomes of methotrexate in patients with rheumatoid arthritis? A systematic review and meta-analysis.
Pharmacogenomics 2017 Jan 18 (2): 175-195. Chen Yuehong, Zou Kun, Sun Jianhong, Yang Yuan, Liu Ga |
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ATIC missense variant affects response to methotrexate treatment in rheumatoid arthritis patients.
Pharmacogenomics 2016 Dec 17 (18): 1971-1978. Kurzawski Mateusz, Malinowski Damian, Szarmach Natalia, Nowak Anna, Goryniak Aleksandra, Pawlik Andrzej, Drozdzik Mar |
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Impact of genetic variants of ATP binding cassette B1, AICAR transformylase/IMP cyclohydrolase, folyl-polyglutamatesynthetase, and methylenetetrahydrofolatereductase on methotrexate toxicity.
Reumatologia clinica 2016 Oct . Sala-Icardo Luis, Lamana Amalia, Ortiz Ana María, García Lorenzo Elena, Moreno Fresneda Pablo, García-Vicuña Rosario, González-Álvaro Isido |
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Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome.
Pharmacogenomics 2016 Sep . Lima Aurea, Bernardes Miguel, Azevedo Rita, Seabra Vitor, Medeiros R |
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Association of the ATIC 347 C/G polymorphism with responsiveness to and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis.
Rheumatology international 2016 Jul . Lee Young Ho, Bae Sang-Che |
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ATIC 347C>G gene polymorphism may be associated with methotrexate-induced adverse events in south Indian Tamil rheumatoid arthritis.
Pharmacogenomics 2016 Jan . Muralidharan Niveditha, Mariaselvam Christina M, Jain Vikramraj K, Gulati Reena, Negi Vir |
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5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis.
Rheumatology international 2015 Apr 35 (4): 619-27. Pastore Serena, Stocco Gabriele, Moressa Valentina, Zandonà Luigi, Favretto Diego, Malusà Noelia, Decorti Giuliana, Lepore Loredana, Ventura Alessand |
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Polymorphisms in genes involved in the mechanism of action of methotrexate: are they associated with outcome in rheumatoid arthritis patients?
Pharmacogenomics 2014 Jun 15 (8): 1079-90. Salazar Juliana, Moya Patricia, Altés Albert, Díaz-Torné César, Casademont Jordi, Cerdà-Gabaroi Dacia, Corominas Hèctor, Baiget Montserr |
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Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: implication of MTHFR rs1801133 and ATIC rs4673993 polymorphisms.
BioMed research international 2014 2014 368681. Lima Aurea, Monteiro Joaquim, Bernardes Miguel, Sousa Hugo, Azevedo Rita, Seabra Vitor, Medeiros R |
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Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure.
Pharmacogenomics 2012 Jul 13 (9): 9. Fransen J, Kooloos WM, Wessels JA, Huizinga TW, Guchelaar HJ, van Riel PL, Barrera P |
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Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients.
The pharmacogenomics journal 2012 Mar . Owen SA, Hider SL, Martin P, Bruce IN, Barton A, Thomson W |
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Association of dihydrofolate reductase (DHFR) -317AA genotype with poor response to methotrexate in patients with rheumatoid arthritis.
Clinical and experimental rheumatology 2012 Feb . Milic V, Jekic B, Lukovic L, Bunjevacki V, Milasin J, Novakovic I, Damnjanovic T, Popovic B, Maksimovic N, Damjanov N, Radunovic G, Pejnovic N, Krajinovic M |
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Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis.
Drug metabolism and pharmacokinetics 2012 27 (2): 192-9. Kato Tomomi, Hamada Akinobu, Mori Shunsuke, Saito Hideyu |
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Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
Annals of the rheumatic diseases 2011 Aug 70 (8): 1395-400. Hinks Anne, Moncrieffe Halima, Martin Paul, Ursu Simona, Lal Sham, Kassoumeri Laura, Weiler Tracey, Glass David N, Thompson Susan D, Wedderburn Lucy R, Thomson Wen |
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Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis.
British journal of clinical pharmacology 2011 Feb 71 (2): 237-43. Yanagimachi Masakatsu, Naruto Takuya, Hara Takuma, Kikuchi Masako, Hara Ryoki, Miyamae Takako, Imagawa Tomoyuki, Mori Masaaki, Kaneko Tetsuji, Morita Satoshi, Goto Hiroaki, Yokota Shump |
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Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis.
Pharmacogenetics and genomics 2009 Dec 19 (12): 935-44. Dervieux Thierry, Wessels Judith A M, van der Straaten Tahar, Penrod Nadia, Moore Jason H, Guchelaar Henk-Jan, Kremer Joel |
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Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians.
Pharmacogenetics and genomics 2009 Oct 19 (10): 823-8. Sharma Shruti, Das Mitashree, Kumar Ashok, Marwaha Vishal, Shankar Subramanian, Singh Paramjeet, Raghu Padmanabhan, Aneja Ritu, Grover Rahul, Arya Vivek, Dhir Varun, Gupta Rajiva, Kumar Uma, Juyal Ramesh C, K Thelma |
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Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.
Rheumatology (Oxford, England) 2009 Jun 48 (6): 613-7. Lee Yvonne C, Cui Jing, Costenbader Karen H, Shadick Nancy A, Weinblatt Michael E, Karlson Elizabeth |
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Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.
The British journal of dermatology 2009 Feb 160 (2): 438-41. Warren R B, Smith R L, Campalani E, Eyre S, Smith C H, Barker J N W N, Worthington J, Griffiths C E |
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A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis.
Arthritis and rheumatism 2007 Jun 56 (6): 1765-75. Wessels Judith A M, van der Kooij Sjoerd M, le Cessie Saskia, Kievit Wietske, Barerra Pilar, Allaart Cornelia F, Huizinga Tom W J, Guchelaar Henk-Jan, |
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Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.
Arthritis and rheumatism 2006 Oct 54 (10): 3095-103. Dervieux Thierry, Greenstein Neal, Kremer Jo |
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Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.
Arthritis and rheumatism 2006 Sep 54 (9): 2830-9. Wessels Judith A M, Kooloos Wouter M, De Jonge Robert, De Vries-Bouwstra Jeska K, Allaart Cornelia F, Linssen Annelies, Collee Gerard, De Sonnaville Peter, Lindemans Jan, Huizinga Tom W J, Guchelaar Henk-J |
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Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.
Arthritis and rheumatism 2006 Feb 54 (2): 607-12. Weisman Michael H, Furst Daniel E, Park Grace S, Kremer Joel M, Smith Katie M, Wallace Daniel J, Caldwell Jacques R, Dervieux Thier |
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Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study.
Annals of the rheumatic diseases 2005 Aug 64 (8): 1180-5. Dervieux T, Furst D, Lein D O, Capps R, Smith K, Caldwell J, Kremer |
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Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis.
Arthritis and rheumatism 2004 Sep 50 (9): 2766-74. Dervieux Thierry, Furst Daniel, Lein Diana Orentas, Capps Robert, Smith Katie, Walsh Michael, Kremer Jo |
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ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients.
Clinical and experimental rheumatology 0 24 (5): 546-54. Takatori R, Takahashi K A, Tokunaga D, Hojo T, Fujioka M, Asano T, Hirata T, Kawahito Y, Satomi Y, Nishino H, Tanaka T, Hirota Y, Kubo |
- Page last reviewed:Jul 30, 2019
- Page last updated:Oct 10, 2019
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