Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Search PHGKB:

Last Posted: Apr 09, 2024
spot light Highlights

What Is Huntington Disease?
R Marcus, JAMA, August 21, 2023

Huntington disease is a rare genetic disease that affects movement, thinking, and behavior. Huntington disease results from an abnormal gene that damages cells in the brain. It is an autosomal dominant genetic disorder, meaning that individuals born to a parent with Huntington disease have a 50% chance of developing the disease. Rarely, patients with Huntington disease have a gene variant that developed spontaneously and was not inherited. Huntington disease affects about 11 to 14 people per 100?000 individuals in Europe and North America and is less common in Africa and East Asia.

A pilot evaluation of an 8-week mindfulness-based stress reduction program for people with pre-symptomatic Huntington's disease.
Sarah Velissaris et al. J Community Genet 2023 7

People with Huntington’s disease (HD) face difficult emotional and practical challenges throughout their illness, including in the pre-symptomatic stage. There are, however, extremely limited psychosocial interventions adapted to or researched for HD. We adapted and piloted an 8-week mindfulness-based stress reduction (MBSR) program in people with pre-symptomatic HD to determine if the program (i) was feasible and acceptable to participants, (ii) resulted in increased mindfulness understanding and skills, and (iii) led to improved psychological adjustment.

Search Result Summary

Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.