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Hot Topics of the Day|PHGKB
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Nov 29, 2021

Last Posted: Nov-29-2021 10:56:44

Omicron—panic mongering or appropriate caution?
H Salisbury, BMJ, November 29, 2021

Covid-19: Omicron may be more transmissible than other variants and partly resistant to existing vaccines, scientists fear
I Torjesen, BMJ, November 29, 2021

Omicron, the SARS-CoV-2 variant responsible for a cluster of cases in South Africa and that is now spreading around the world, is the most heavily mutated variant to emerge so far and carries mutations similar to changes seen in previous variants of concern associated with enhanced transmissibility and partial resistance to vaccine induced immunity.

Dosing interval strategies for two-dose COVID-19 vaccination in 13 low- and middle-income countries of Europe: health impact modelling and benefit-risk analysis
Y Liu et al, MEDRXIV, November 28, 2021

Analytical sensitivity and effectiveness of different SARS-CoV-2 testing options
N Lelie et al, MEDRXIV, November 28, 2021

A fourth dose of the mRNA-1273 SARS-CoV-2 vaccine improves serum neutralization against the delta variant in kidney transplant recipients
I Benotmane et al, MEDRXIV, November 28, 2021

Emergence and Spread of the SARS-CoV-2 Variant of Concern Delta Across Different Brazilian Regions
I Arantes et al, MEDRXIV, November 28, 2021

Modelling the interplay of SARS-CoV-2 variants in the United Kingdom.
N Barreiro et al, MEDRXIV, November 28, 2021

Management and containment of a SARS-CoV-2 Beta variant outbreak at the Malawi University of Science and Technology
GP Bandawe et al, MEDRXIV, November 28, 2021

Show us the Data: Global COVID-19 Wastewater Monitoring Efforts, Equity, and Gaps
CC Naughton et al, MEDRXIV, November 28, 2021

Unlike COVID-19 case and mortality data, there was not a global dashboard to track wastewater monitoring of SARS-CoV-2 RNA worldwide. This study provides a one year review of the COVIDPoops19 global dashboard of universities, sites, and countries monitoring SARS-CoV-2 RNA in wastewater. Methods to assemble the dashboard combined standard literature review, direct submissions, and daily, social media keyword searches. Over 200 universities, 1,000 sites, and 55 countries with 59 dashboards monitor wastewater for SARS-CoV-2 RNA. However, monitoring is primarily in high-income countries (65 percent) with less access to this valuable tool in low and middle income countries (35 percent).

Genetic testing decisions in non-western cultures: an opportunity for intergenerational decision making
E Turbitt et al, EJHG, November 29, 2021

While decision aids improve shared decision making, most theoretical and empirical evidence is based on western ideals such as supporting an individual’s autonomous decision making, in a non-directive way, to facilitate informed choice. Shared decision making and decision aids have not been widely researched in diverse communities or non-western populations [1]. The development and testing of decision aids in non-western cultures can help to understand the applicability of shared decision making and associated interventions across a variety of contexts.


Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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