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COVID-10 GPH

COVID-19 GPH|Home|PHGKB

Last data update: Apr 12, 2021 . (Total: 21967 Documents since 2020)
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U.K. variant isn't linked to more severe disease or death, study finds The variant known as B.1.1.7 is now the dominant coronavirus strain in Europe and the U.S. Scientists say there is still much to learn about the more contagious virus.
NBC News, April 12, 2021
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study
MS Graham et al, The Lancet, April 12, 2021
The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in England. We aimed to investigate whether increases in the proportion of infections with this variant are associated with differences in symptoms or disease course, reinfection rates, or transmissibility.
Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study
D Frampton et al, The Lancet, April 12, 2021
Of 496 patients with samples positive for SARS-CoV-2 on PCR and who met inclusion criteria, 341 had samples that could be sequenced. 198 (58%) of 341 had B.1.1.7 infection and 143 (42%) had non-B.1.1.7 infection. We found no evidence of an association between severe disease and death and lineage (B.1.1.7 vs non-B.1.1.7) in unadjusted analyses, or in analyses adjusted for hospital, sex, age, comorbidities, and ethnicity.
Remote Patient Monitoring — Overdue or Overused?
K Mecklai et al, NEJM, April 10, 2021
The Covid-19 pandemic has challenged clinicians to find innovative ways to provide essential services while minimizing risks for themselves and their patients. These approaches increasingly leverage remote patient monitoring (RPM), using technology to support treatment for chronic conditions. As the use of RPM services grows, clinicians, payers, and patients face important questions regarding the volume, value, and appropriate use of this care model.
Correlates of protection from SARS-CoV-2 infection
F Krammer, Lancet, April 9, 2021
How could a COVID vaccine cause blood clots? Scientists race to investigate
Nature News, April 9, 2021
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Get Protected! Recommendations for Staff in IR.
Bartal Gabriel, et al. Cardiovascular and interventional radiology 2021 4 0.
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Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial.
Horwood Jeremy, et al. Trials 2021 4 0. (1) 263
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Silencing of SARS-CoV-2 with modified siRNA-peptide dendrimer formulation.
Khaitov Musa, et al. Allergy 2021 4 0.
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COVID-19 And Zika: An emerging dilemma for Brazil.
Costa Ana Carla Dos Santos, et al. Journal of medical virology 2021 4 0.
Coronavirus genomic nsp14-ExoN, structure, role, mechanism, and potential application as a drug target.
Tahir Mohammed, et al. Journal of medical virology 2021 4 0.
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Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19.
Casagrande Maria, et al. The British journal of ophthalmology 2021 4 0.
Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains.
Bartas Martin, et al. Briefings in bioinformatics 2021 4 0.
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Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults.
Bullard Jared, et al. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2021 4 0.
Prevalence, clinical characteristics and outcomes of Guillain-Barré syndrome spectrum associated with COVID-19: a systematic review and meta-analysis.
Palaiodimou Lina, et al. European journal of neurology 2021 4 0.
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GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
Zhao Ming, et al. Nature communications 2021 4 0. (1) 2114
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Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.
Gaziano Liam, et al. Nature medicine 2021 4 0.
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Interferon-induced transmembrane protein-3 genetic variant rs12252 is associated with COVID-19 mortality.
Alghamdi Jahad, et al. Genomics 2021 4 0.
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LamPORE SARS-CoV-2 diagnosis and genotyping: A preliminary report.
Morsli M, et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2021 3 0. 104815
The endless frontier of tRNA synthetases.
Schimmel Paul, et al. The Enzymes 2020 0 0. 1-10
Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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