Advanced Molecular Detection Clips Content (Published on 12/22/2022)
NEWS
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The science events to watch for in 2023
Naddaf M. Nature, Dec 19, 2022. -
KU Leuven-led Project Aims to Develop Mass PCR Testing Platform for Future Pandemics
Petrone J. 360dx, Dec 16, 2022. -
BioNtech ready to ship first mRNA vaccine factory kit to Africa
Reuters, Dec 21, 2022. -
Sequencing tests confirm polio transmission in Indonesia
Schnirring L. CIDRAP, Dec 20, 2022.
POLICY
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Fact Sheet: Biden Administration Announces COVID-19 Winter Preparedness Plan
White House, Dec 15, 2022.
CONCEPTS / COMMENTS
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Genomic epidemiology on the move.
Wilson Catherine N et al. Nature reviews. Microbiology 2022 12 1
METHODS / TOOLS
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Ten simple rules and a template for creating workflows-as-applications.
Roach Michael J et al. PLoS computational biology 2022 12 (12) e1010705 -
Restriction Endonuclease-Based Modification-Dependent Enrichment (REMoDE) of DNA for Metagenomic Sequencing.
Enam Syed Usman et al. Applied and environmental microbiology 2022 12 e0167022 -
Common data model for COVID-19 datasets.
Wegner Philipp et al. Bioinformatics (Oxford, England) 2022 10 (24) 5466-5468 -
Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.
Hahn Georg et al. BMC bioinformatics 2022 12 (1) 547 -
Benchmarking Bioinformatic Tools for Amplicon-Based Sequencing of Norovirus.
Fitzpatrick Amy H et al. Applied and environmental microbiology 2022 12 e0152222
EVOLUTION / ECOLOGY / POPULATIONS
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Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand.
Noisumdaeng Pirom et al. PeerJ 2022 12 e14419 -
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA.
Wanyi Huang et al. Cell Host Microbe 2022 12 (1) 112-123.e4 -
Plasmodium malariae structure and genetic diversity in sub-Saharan Africa determined from microsatellite variants and linked SNPs in orthologues of antimalarial resistance genes.
Oriero Eniyou C et al. Scientific reports 2022 12 (1) 21881 -
Insights into the genetic landscape and presence of Cochliomyia hominivorax in the Caribbean.
Tietjen Mackenzie et al. Parasitology research 2022 12
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape.
Iwasawa Junichiro et al. PLoS biology 2022 12 (12) e3001920 -
Prevalence of HIV drug resistance in Nigeria: results from a cross-sectional, population-based survey of Nigerian adults with unsuppressed viral load.
Aliyu Gambo G et al. AIDS (London, England) 2022 12 (2) 333-339 -
Integrative genetic manipulation of Plasmodium cynomolgi reveals MultiDrug Resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine.
Ward Kurt E et al. The Journal of infectious diseases 2022 12 -
A next generation targeted amplicon sequencing method to screen for insecticide resistance mutations in Aedes aegypti populations reveals a rdl mutation in mosquitoes from Cabo Verde.
Collins Emma L et al. PLoS neglected tropical diseases 2022 12 (12) e0010935
DETECTION / DIAGNOSIS
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Sewage-based surveillance shows presence of Klebsiella pneumoniae resistant against last resort antibiotics in the population in Bergen, Norway.
Radisic Vera et al. International journal of hygiene and environmental health 2022 12 114075 -
A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection.
Mosquera-Restrepo Sergio Fabián et al. Nature communications 2022 12 (1) 7751 -
Metagenomic-based surveillance systems for antibiotic resistance in non-clinical settings.
Pillay Stephanie et al. Frontiers in microbiology 2022 12 1066995 -
SARS-CoV-2 genomic surveillance in Malaysia: displacement of B.1.617.2 with AY lineages as the dominant Delta variants and the introduction of Omicron during the fourth epidemic wave.
Azami Nor Azila Muhammad et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 11 216-226 -
SARS-CoV-2 infection and persistence in the human body and brain at autopsy.
Stein Sydney R et al. Nature 2022 12 (7941) 758-763 -
Characterizing SARS-CoV-2 transcription of subgenomic and genomic RNAs during early human infection using multiplexed droplet digital PCR.
Hwang Hyon S et al. The Journal of infectious diseases 2022 12 -
Infectious diseases genomic surveillance capacity in the Caribbean: A retrospective analysis of SARS-CoV-2
Lucien MA, et al. Lancet Infect Dis, Dec 19, 2022. -
Digital PCR discriminates between SARS-CoV-2 Omicron variants and immune escape mutations
Holland SC, et al. medRxiv, Dec 19, 2022. -
A Multiplex PCR and DNA-Sequencing Workflow on Serum for the Diagnosis and Species Identification for Invasive Aspergillosis and Mucormycosis.
Imbert S et al. Journal of clinical microbiology 2022 12 e0140922
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission.
Koolman Leonard et al. PLoS neglected tropical diseases 2022 12 (12) e0010982 -
Next-Generation Sequencing Approaches to Predicting Antimicrobial Susceptibility Testing Results.
Yee Rebecca et al. Clinics in laboratory medicine 2022 11 (4) 557-572 -
Investigation of a Candida auris outbreak in a skilled nursing facility - Virginia, United States, October 2020-June 2021.
Ansley Waters et al. Am J Infect Control 2022 12 (4) 472-474
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern.
Parray Hilal Ahmad et al. PLoS pathogens 2022 12 (12) e1010994 -
Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Hospitalization Among Immunocompetent Adults Aged ≥65 Years — IVY Network, 18 States, September 8–November 30, 2022
Surie D, et al. MMWR, Dec 16, 2022.
HOST-MICROBE INTERACTIONS
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Genome-Wide Association Studies Identify an Association of Transferrin Binding Protein B Variation and Invasive Serogroup Y Meningococcal Disease in Older Adults.
Maynard-Smith Laura et al. The Journal of infectious diseases 2022 11 (12) 2204-2214 -
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution.
Cao Yunlong et al. Nature 2022 12 -
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Lee Danyel et al. Science (New York, N.Y.) 2022 12 eabo3627 -
ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants.
Zhang Lingxin et al. Human molecular genetics 2022 7 (24) 4183-4192 -
The role of angiotensin I converting enzyme insertion/deletion polymorphism in the severity and outcomes of COVID-19 patients.
Rezaei Mitra et al. Frontiers in genetics 2022 12 1035796 -
Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells.
Nikesjö Frida et al. Clinical epigenetics 2022 12 (1) 172 -
The immunogenetics of COVID-19.
Hollenbach Jill A et al. Immunogenetics 2022 12 1-12 -
Adaptation to HLA-associated immune pressure over the course of HIV infection and in circulating HIV-1 strains.
Alves Eric et al. PLoS pathogens 2022 12 (12) e1010965 -
Cytochrome P450 2D6 (CYP2D6) and glucose-6-phosphate dehydrogenase (G6PD) genetic variations in Thai vivax malaria patients: Implications for 8-aminoquinoline radical cure.
Chamchoy Kamonwan et al. PLoS neglected tropical diseases 2022 12 (12) e0010986
Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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