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Scan|Criteria|PHGKB

Genomics Precision Health Scan Data Selection Criteria

Goal: identify articles describing the evaluation of genomic applications and interventions, including their 1) clinical utility, 2) subsequent evidence-based recommendations, guidelines and policies, 3) use in practice, and 4) effect on the health and disease burden within the population.

Include:

  • Research that promotes the integration of genomics into real-world practice settings and improved population health outcomes (T2-T4 phases of translational research).
  • Observational or experimental studies that evaluate genomic interventions, reporting on clinical validity, clinical utility and/or their comparative effectiveness.
  • Systematic reviews that report on genomics evidence-based interventions.
  • Pre-implementation studies identifying barriers and facilitators to applications and interventions.
  • Implementation and dissemination studies that identify effective strategies and/or measure outcomes including acceptability, adoption, appropriateness, cost, feasibility, fidelity, etc.
  • Publications of guidelines and evidence reports on genomics applications.
  • Expert opinion articles, editorials and nonsystematic reviews determined, by consensus, as significant for moving translational research forward.

Exclude:

  • Studies of the characterization and development of candidate genomic health applications (T0-T1 phases of translational research).
  • Epidemiologic studies of gene-disease association (Human Genome Epidemiology-separate database in PHGKB).
  • Non-human genomics application studies.
  • Case studies.

Non-Genomics Precision Health Scan Data Selection Criteria

Goal: identify articles describing the evaluation of non-genomics precision health applications and interventions, including their 1) clinical utility, 2) subsequent evidence-based recommendations, guidelines and policies, 3) use in practice, and 4) effect on the health and disease burden within the population.

Include:

  • Research that promotes the integration of precision health into real-world practice settings and improved population health outcomes (T2-T4 phases of translational research).
  • Observational or experimental studies that evaluate precision health interventions, reporting on clinical validity, clinical utility and/or their comparative effectiveness.
  • Systematic reviews that report on precision health evidence-based interventions.
  • Pre-implementation studies identifying barriers and facilitators to applications and interventions.
  • Implementation and dissemination studies that identify effective strategies and/or measure outcomes including acceptability, adoption, appropriateness, cost, feasibility, fidelity, etc.
  • Publications of guidelines and evidence reports on precision health applications.
  • Expert opinion articles, editorials and nonsystematic reviews determined, by consensus, as significant for moving translational research forward.

Exclude:

  • Basic science studies .
  • Non-human precision health studies.
  • Case studies.
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