Human Genome Epidemiology Literature Finder
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Records 1 - 30 (of 60 Records) |
| Query Trace: Leukopenia and NUDT15[original query] |
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| NUDT15 and TPMT Genetic Polymorphisms Are Related to Azathioprine Intolerance in Chinese Patients with Rheumatic Diseases. Genetic testing and molecular biomarkers 2019 9 23 (10): 751-757. Yang Jing, Wang Peile, Qin Zifei, Jia Mengmeng, Zhang Congmin, Tian Xueke, Zheng Yunbo, Zhang Ailing, Zhang Xiaojian, Liu Shengy |
| An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients. The pharmacogenomics journal 2019 Dec . Chen Sylvia, Tan Wei Zhi, Sutiman Natalia, Lim Cindy, Lee Sze Sing, Leong Wai Fook, Tjai Madeline, Wang Chunyan, Kong Chris San Choon, Chuah Sai Wei, Schwender Brian John, Chan Webber, Shim Hang Hock, Lim Wee Chian, Khor Chiea Chuen, Ling Khoon Lin, Chowbay Balr |
| Nucleoside diphosphate-linked moiety X-type motif 15 R139C genotypes impact 6-thioguanine nucleotide cut-off levels to predict thiopurine-induced leukopenia in Crohn's disease patients. World journal of gastroenterology 2019 10 25 (38): 5850-5861. Zhu Xia, Chao Kang, Li Miao, Xie Wen, Zheng Hong, Zhang Jin-Xin, Hu Pin-Jin, Huang Min, Gao Xiang, Wang Xue-Di |
| A rare case of Azathioprine-induced leukopenia in an European woman. Acta clinica Belgica 2020 Aug 1-5. Séverine Wautier, Xavier De Koninck, Jean-Charles Coc |
| NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease. Intestinal research 2020 6 18 (3): 275-281. Matsuoka Katsuyos |
| Effects of various genetic polymorphisms on thiopurine treatment-associated outcomes for Korean patients with Crohn's disease. British journal of clinical pharmacology 2020 May . Choi Rihwa, Lee Mi-Na, Kim Kyunga, Baek Sun-Young, Kim Tae Jun, Hong Sung Noh, Kim Young-Ho, Lee Soo-Yo |
| Prevention of thiopurine-induced early leukopenia in a Korean pediatric patient with Crohn's disease who turned out to possess homozygous mutations in NUDT15 R139C. Yeungnam University journal of medicine 2020 5 37 (4): 332-336. Bae Jaewoan, Choe Byung-Ho, Kang B |
| Screening of Novel Pharmacogenetic Candidates for Mercaptopurine-Induced Toxicity in Patients With Acute Lymphoblastic Leukemia. Frontiers in pharmacology 2020 4 11 267. Cao Minyuan, Yin Dandan, Qin Yun, Liao Fei, Su Yali, Xia Xuyang, Gao Ju, Zhu Yiping, Zhang Wei, Shu Yang, Lu Xiao |
| Precision therapy of 6-mercaptopurine in Chinese children with acute lymphoblastic leukaemia. British journal of clinical pharmacology 2020 Feb . Zhou Yue, Wang Li, Zhai Xiao-Ying, Wen Li, Tang Fang, Yang Fan, Liu Xi-Ting, Dong Lei, Zhi Li-Juan, Shi Hai-Yan, Hao Guo-Xiang, Zheng Yi, Jacqz-Aigrain Evelyne, Wang Tian-You, Zhao W |
| Predictive Value of NUDT15 Variants on Neutropenia Among Han Chinese Patients with Dermatologic Diseases: A Single-Center Observational Study. Dermatology and therapy 2020 Feb . Huang Po-Wei, Tseng Yu-Hsian, Tsai Tsen-Fa |
| Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation. Journal of gastroenterology 2021 9 56 (11): 999-1007. Toyonaga Takahiko, Kobayashi Taku, Kuronuma Satoshi, Ueno Aito, Kiyohara Hiroki, Okabayashi Shinji, Takeuchi Osamu, Redfern Christopher P F, Terai Hideki, Ozaki Ryo, Sagami Shintaro, Nakano Masaru, Coulthard Sally A, Tanaka Yoichi, Hibi Toshifu |
| TPMT and NUDT15 polymorphisms in thiopurine induced leucopenia in inflammatory bowel disease: a prospective study from India. BMC gastroenterology 2021 Aug 21 (1): 327. Grover Narinder, Bhatia Prateek, Kumar Antriksh, Singh Minu, Lad Deepesh, Mandavdhare Harshal S, Samanta Jayanta, Prasad Kaushal K, Dutta Usha, Sharma Vish |
| Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis. Scientific reports 2021 Apr 11 (1): 7984. Miao Qiang, Yan Lin, Zhou Yanhong, Li Yi, Zou Yuangao, Wang Lanlan, Bai Yangjuan, Zhang Junlo |
| Effect of NUDT15 polymorphisms on early hematological safety of low-dose azathioprine in Chinese patients with pemphigus vulgaris: A prospective cohort study. The Journal of dermatology 2021 Dec . Zhou Xingli, Cheng Liangliang, Wang Yiyi, Gou Hui, Ju Ke, Lan TianJiao, Zhan Tongying, Li GaoJie, Gu Yuanxia, Sun Yeting, Xu Yan, Sun Yukun, Zhou Yanhong, Li W |
| Meta-Analysis of NUDT15 Genetic Polymorphism on Thiopurine-Induced Myelosuppression in Asian Populations. Frontiers in pharmacology 2021 12 12 784712. Khaeso Kanyarat, Udayachalerm Sariya, Komvilaisak Patcharee, Chainansamit Su-On, Suwannaying Kunanya, Laoaroon Napat, Kuwatjanakul Pitchayanan, Nakkam Nontaya, Sukasem Chonlaphat, Puangpetch Apichaya, Tassaneeyakul Wichittra, Chaiyakunapruk Natho |
| ABCC4, ITPA, NUDT15, TPMT and their interaction as genetic predictors of 6-mercaptopurine intolerance in chinese patients with acute lymphoblastic leukemia. Pediatric hematology and oncology 2021 10 39 (3): 254-266. Fan Paroni O L, Leung Kam-Tong, Chan Kathy Y Y, Leung Alex W K, Lam Grace K S, Chow Terry T W, Cheng Frankie W T, Yuen Liz Y P, Moriyama Takaya, Yang Jun J, Li Chi-Ko |
| Effects of TPMT, NUDT15, and ITPA Genetic Variants on 6-Mercaptopurine Toxicity for Pediatric Patients With Acute Lymphoblastic Leukemia in Yunnan of China. Frontiers in pediatrics 2021 10 9 719803. Mao Xiaoyan, Yin Runxiu, Sun Gaoyuan, Zhou Yan, Yang Chunhui, Fang Chunlian, Wu Yuhong, Cui Tingting, Liu Li, Gan Jiaxin, Tian X |
| Ancestry and TPMT-VNTR Polymorphism: Relationship with Hematological Toxicity in Uruguayan Patients with Acute Lymphoblastic Leukemia. Frontiers in pharmacology 2020 11 594262. Burgueño-Rodríguez Gabriela, Méndez Yessika, Olano Natalia, Dabezies Agustín, Bertoni Bernardo, Souto Jorge, Castillo Luis, da Luz Julio, Soler Ana Mar |
| XDH genotypes through gene-gene interactions with NUDT15 affect azathioprine-induced leukopenia in Chinese patients. Pharmacogenomics 2022 8 23 (12): 671-682. Liu Jiquan, Wen Zhiyong, Huang Sichao, Zhang Xiaomin, Ai Xinbo, Qian Jiaji |
| Implementation of NUDT15 Genotyping to Prevent Azathioprine-Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population. Clinical pharmacology and therapeutics 2022 Jul . Wang Chuang-Wei, Chi Min-Hui, Tsai Tsen-Fang, Yu Kuang-Hui, Kao Hsiao-Wen, Chen Hsiang-Cheng, Chen Chun-Bing, Lu Chun-Wei, Chen Wei-Ti, Chang Ya-Ching, Chang Chih-Jung, Chang Yun-Ting, Jan Wu Yeong-Jian, Chang Chee-Jen, Huang Yu Huei, Ng Chau-Yee, Huang Po-Wei, Lin Yu-Jr, Hui Rosaline Chung-Yee, Chung Wen-Hung, |
| Nudix hydrolase 15 (NUDT15) loss-of-function variants in an Australian inflammatory bowel disease population. Internal medicine journal 2022 3 52 (11): 1971-1977. Afrin Sadia, Simms Lisa A, Lord Anton, Radford-Smith Graham |
| Inosine Triphosphate Pyrophosphatase and NUDT15 are Good Predictors of Clinical Outcomes in Thiopurine-Treated Chinese Patients with Inflammatory Bowel Disease. Therapeutic drug monitoring 2022 Jan . Luo Xuemei, Yan Simin, Jin Lu, Zhu Huaijun, Zhang Xiaoqi, Ge Weiho |
| NUDT15 intermediate metabolisers are associated with lower loss of response in paediatric Crohn's disease patients treated by combination treatment with infliximab and azathioprine. Alimentary pharmacology & therapeutics 2022 1 55 (8): 1008-1015. Kim Eun Sil, Choi Sujin, Choi So Yoon, Park Ji Hyung, Choe Byung-Ho, Lee Soo-Youn, Kim Mi Jin, Choe Yon Ho, Kang B |
| Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease. BMC gastroenterology 2023 7 23 (1): 239. Shizuka Suzuki, Kan Uchiyama, Yutaro Motoi, Yuuki Yoshii, Yukari Inoue, Takahiro Kubota, Shunichi Odahara, Yuichiro Ohtaki, Shinichiro Takami, Zensho Ito, Nobuhiro Sato, Toshifumi Ohkusa, Shigeo Koido, Masayuki Saru |
| Prevalence of NUDT15 genetic variants and incidence of thiopurine-induced leukopenia in Inflammatory Bowel Disease: A systematic review and meta-analysis. Journal of Crohn's & colitis 2023 6 . Natalie Yu, Danujan Sriranganathan, Gareth J Walker, Aleksejs Sazonovs, Helen Wilding, Christopher Roberts, Nicholas A Kennedy, Tariq Ahmad, Ray K Boyapati, Nik S Ding, Jonathan P Seg |
| Single-Nucleotide Polymorphisms, c.415C?>?T (Arg139Cys) and c.416G?>?A (Arg139His), in the NUDT15 Gene Are Associated with Thiopurine-Induced Leukopenia. Biological & pharmaceutical bulletin 2023 3 46 (3): 412-418. Isono Tetsuichiro, Hira Daiki, Ikeda Yoshito, Kawahara Masahiro, Noda Satoshi, Nishida Atsushi, Inatomi Osamu, Fujimoto Noriki, Andoh Akira, Terada Tomohiro, Morita Shin- |
| Association of NUDT15 gene polymorphism with adverse reaction, treatment efficacy, and dose of 6-mercaptopurine in patients with acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica 2023 10 . Shan Du, Xuefei Huang, Xia He, Mian Mao, Min Chen, Rong Zhang, Huikai Shao, Ziyan Lv, Xinxia Liu, Junlan Chu |
| ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease. Revista de gastroenterologia de Mexico (English) 2023 1 . Jena A, Grover N, Bhatia P, Singh M, Lad D, Prasad K K, Singh H, Dutta U, Sharma |
| Ancestral diversity in pharmacogenomics affects treatment for Hispanic/Latine populations with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024 8 . S Ioannou, A Beecham, L Gomez, R Dauer, N Khakoo, L Pascual, M Quintero, J Lopez, J S Leavitt, N Solis, M Ortega, A R Deshpande, D H Kerman, S Proksell, E A Torres, T Haritunians, D Li, M T Abreu, D P B McGovern, J L McCauley, O M Dam |
| Association of TPMT and NUDT15 gene polymorphisms with azathioprine-induced leukopenia: A case-control study in Eastern India. Indian journal of pharmacology 2024 7 56 (3): 166-171. Sneha Mitra, Abhijnan Ghosh, Suparna Chatterjee, Mitali Chatterjee, Pradyot Sinhamahapat |
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