HuGE Literature Finder
Records 1-30
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Phase II evaluation of copanlisib, a selective inhibitor of Pi3kca, in patients with persistent or recurrent endometrial carcinoma harboring PIK3CA hotspot mutations: An NRG Oncology study (NRG-GY008).
Gynecologic oncology reports 2020 Feb 31 100532. Santin Alessandro D, Filiaci Virginia, Bellone Stefania, Ratner Elena S, Mathews Cara A, Cantuaria Guilherme, Gunderson Camille C, Rutledge Teresa, Buttin Barbara M, Lankes Heather A, Frumovitz Michael, Khleif Samir N, Huh Warner K, Birrer Michael |
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Detection of somatic mutations in peritoneal lavages and plasma of endometrial cancer patients: a proof-of-concept study.
International journal of cancer 2020 Jan . Mayo-de-Las-Casas Clara, Velasco Ana, Sanchez Douglas, Martínez-Bueno Alejandro, Garzón-Ibáñez Mónica, Gatius Sònia, Ruiz-Miró Maria, Gonzalez-Tallada Xavier, Llordella Ivana, Tresserra Francesc, Rodríguez Sonia, Aldeguer Erika, Roman-Canal Berta, Bertran-Alamillo Jordi, García-Peláez Beatriz, Rosell Rafael, Molina-Vila Miguel A, Matias-Guiu Xavi |
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Identification of a Gene Panel for Endometrioid Endometrial Cancer: a Possible Prognostic Value?
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan . Malentacchi Francesca, Turrini Irene, Sorbi Flavia, Projetto Elisabetta, Castiglione Francesca, Vergoni Federica, Amunni Gianni, Fambrini Massimiliano, Petraglia Felice, Noci Ivo, Pillozzi Sere |
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Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago and California Consortia (NCI9322/PHL86).
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Jan . Dhani Neesha C, Hirte Hal W, Wang Lisa, Burnier Julia V, Jain Angela, Butler Marcus O, Welch Stephen, Fleming Gini F, Hurteau Jean, Matsuo Koji, Matei Daniela, Jimenez Waldo, Johnston Carolyn, Cristea Mihaela, Tonkin Katia, Ghatage Prafull, Lheureux Stephanie, Mehta Anjali, Quintos Judy, Tan Qian, Kamel-Reid Suzanne, Ludkovski Olga, Tsao Ming-Sound, Wright John J, Oza Amit |
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Phase II, 2-Stage, 2-Arm, PIK3CA Mutation Stratified Trial of MK-2206 in Recurrent Endometrial Cancer.
International journal of cancer 2019 Nov . Myers Andrea P, Konstantinopoulos Panagiotis A, Barry William T, Luo Weixiu, Broaddus Russell R, Makker Vicky, Drapkin Ronny, Liu Joyce, Doyle Austin, Horowitz Neil S, Meric-Bernstam Funda, Birrer Michael, Aghajanian Carol, Coleman Robert L, Mills Gordon B, Cantley Lewis C, Matulonis Ursula A, Westin Shannon |
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Different mutation profiles between epithelium and stroma in endometriosis and normal endometrium.
Human reproduction (Oxford, England) 2019 Oct 34 (10): 1899-1905. Suda Kazuaki, Nakaoka Hirofumi, Yoshihara Kosuke, Ishiguro Tatsuya, Adachi Sosuke, Kase Hiroaki, Motoyama Teiichi, Inoue Ituro, Enomoto Takayu |
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Molecular profiling and molecular classification of endometrioid ovarian carcinomas.
Gynecologic oncology 2019 Jul . Cybulska Paulina, Paula Arnaud Da Cruz, Tseng Jill, Leitao Mario M, Bashashati Ali, Huntsman David G, Nazeran Tayyebeh M, Aghajanian Carol, Abu-Rustum Nadeem R, DeLair Deborah F, Shah Sohrab P, Weigelt Brit |
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Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer.
Oncology reports 2019 Mar 41 (3): 1560-1574. Malentacchi Francesca, Turrini Irene, Sorbi Flavia, Projetto Elisabetta, Castiglione Francesca, Fambrini Massimiliano, Petraglia Felice, Pillozzi Serena, Noci I |
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Efficacy of liquid-based genetic diagnosis of endometrial cancer.
Cancer science 2018 Oct . Matsuura Motoki, Yamaguchi Kiyoshi, Tamate Masato, Satohisa Seiro, Teramoto Mizue, Iwasaki Masahiro, Sugita Shintaro, Hasegawa Tadashi, Koubo Rika, Takane Kiyoko, Ikenoue Tsuneo, Furukawa Yoichi, Saito Tsuyos |
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Progestin-associated shift of meningioma mutational landscape.
Annals of oncology : official journal of the European Society for Medical Oncology 2017 Nov . Peyre M, Gaillard S, de Marcellus C, Giry M, Bielle F, Villa C, Boch A L, Loiseau H, Baussart B, Cazabat L, Raffin-Sanson M L, Sanson M, Kalamarides |
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Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.
Cancer 2017 Sep 123 (17): 3261-3268. Le Gallo Matthieu, Rudd Meghan L, Urick Mary Ellen, Hansen Nancy F, Zhang Suiyuan, , Lozy Fred, Sgroi Dennis C, Vidal Bel August, Matias-Guiu Xavier, Broaddus Russell R, Lu Karen H, Levine Douglas A, Mutch David G, Goodfellow Paul J, Salvesen Helga B, Mullikin James C, Bell Daphne |
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A multicenter, single-arm, open-label, phase 2 study of apitolisib (GDC-0980) for the treatment of recurrent or persistent endometrial carcinoma (MAGGIE study).
Cancer 2016 Sep . Makker Vicky, Recio Fernando O, Ma Ling, Matulonis Ursula A, Lauchle Jennifer O, Parmar Hema, Gilbert Houston N, Ware Joseph A, Zhu Rui, Lu Shan, Huw Ling-Yuh, Wang Yulei, Koeppen Hartmut, Spoerke Jill M, Lackner Mark R, Aghajanian Carol |
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Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
Gynecologic oncology 2016 Apr 141 (1): 43-8. Myers Andrea P, Filiaci Virginia L, Zhang Yuping, Pearl Michael, Behbakht Kian, Makker Vicky, Hanjani Parviz, Zweizig Susan, Burke James J, Downey Gordon, Leslie Kimberly K, Van Hummelen Paul, Birrer Michael J, Fleming Gini |
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PTEN loss is a context-dependent outcome determinant in obese and non-obese endometrioid endometrial cancer patients.
Molecular oncology 2015 Oct 9 (8): 1694-703. Westin Shannon N, Ju Zhenlin, Broaddus Russell R, Krakstad Camilla, Li Jane, Pal Navdeep, Lu Karen H, Coleman Robert L, Hennessy Bryan T, Klempner Samuel J, Werner Henrica M J, Salvesen Helga B, Cantley Lewis C, Mills Gordon B, Myers Andrea |
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Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2015 Jun 28 (6): 836-44. Stelloo Ellen, Bosse Tjalling, Nout Remi A, MacKay Helen J, Church David N, Nijman Hans W, Leary Alexandra, Edmondson Richard J, Powell Melanie E, Crosbie Emma J, Kitchener Henry C, Mileshkin Linda, Pollock Pamela M, Smit Vincent T, Creutzberg Carien |
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Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway.
Oncotarget 2014 May 5 (10): 3029-38. Wheler Jennifer J, Moulder Stacy L, Naing Aung, Janku Filip, Piha-Paul Sarina A, Falchook Gerald S, Zinner Ralph, Tsimberidou Apostolia M, Fu Siqing, Hong David S, Atkins Johnique T, Yelensky Roman, Stephens Philip J, Kurzrock Razel |
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Molecular pathogenesis of endometrial cancers in patients with Lynch syndrome.
Cancer 2013 Aug 119 (16): 3027-33. Huang Marilyn, Djordjevic Bojana, Yates Melinda S, Urbauer Diana, Sun Charlotte, Burzawa Jennifer, Daniels Molly, Westin Shannon N, Broaddus Russell, Lu Kar |
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High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma.
Gynecologic oncology 2013 Feb 128 (2): 327-34. Garcia-Dios Diego A, Lambrechts Diether, Coenegrachts Lieve, Vandenput Ingrid, Capoen An, Webb Penelope M, Ferguson Kaltin, , Akslen Lars A, Claes Bart, Vergote Ignace, Moerman Philippe, Van Robays Johan, Marcickiewicz Janusz, Salvesen Helga B, Spurdle Amanda B, Amant Frédér |
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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2013 Jan . Zhao S, Choi M, Overton JD, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N, Hui P, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Carrara L, Pecorelli S, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Stiegler AL, Mane S, Boggon TJ, Schlessinger J, Lifton RP, Santin AD |
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Predicting everolimus treatment efficacy in patients with advanced endometrial carcinoma: a GINECO group study.
Targeted oncology 2012 Dec . Trédan O, Treilleux I, Wang Q, Gane N, Pissaloux D, Bonnin N, Petit T, Cretin J, Bonichon-Lamichhane N, Priou F, Lavau-Denes S, Mari V, Freyer G, Lebrun D, Alexandre J, Ray-Coquard I |
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Racial differences in oncogene mutations detected in early-stage low-grade endometrial cancers.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2012 Oct 22 (8): 1367-72. Cote Michele L, Atikukke Govindaraja, Ruterbusch Julie J, Olson Sara H, Sealy-Jefferson Shawnita, Rybicki Benjamin A, Alford Sharon Hensley, Elshaikh Mohammad A, Gaba Arthur R, Schultz Daniel, Haddad Ramsi, Munkarah Adnan R, Ali-Fehmi Rou |
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PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Mar 30 (8): 777-82. Janku Filip, Wheler Jennifer J, Westin Shannon N, Moulder Stacy L, Naing Aung, Tsimberidou Apostolia M, Fu Siqing, Falchook Gerald S, Hong David S, Garrido-Laguna Ignacio, Luthra Rajyalakshmi, Lee J Jack, Lu Karen H, Kurzrock Razel |
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Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.
Journal of cancer research and clinical oncology 2012 Mar 138 (3): 377-85. Wang Li-E, Ma Hongxia, Hale Katherine S, Yin Ming, Meyer Larissa A, Liu Hongliang, Li Jie, Lu Karen H, Hennessy Bryan T, Li Xuesong, Spitz Margaret R, Wei Qingyi, Mills Gordon |
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FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.
PloS one 2012 7 (2): e30801. Byron Sara A, Gartside Michael, Powell Matthew A, Wellens Candice L, Gao Feng, Mutch David G, Goodfellow Paul J, Pollock Pamela |
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Molecular analysis of endometrial pathogenesis in Lynch syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): 5095. Huang M, Djordjevic B, Urbauer D, Westin S N, Sun C C, Burzawa J K, Meyer L, Bodurka D C, Broaddus R, Lu K |
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A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Mar 17 (6): 1331-40. Rudd Meghan L, Price Jessica C, Fogoros Sarah, Godwin Andrew K, Sgroi Dennis C, Merino Maria J, Bell Daphne |
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Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study.
Gynecologic oncology 2011 Feb 120 (2): 167-73. Lacey James V, Yang Hannah, Gaudet Mia M, Dunning Alison, Lissowska Jolanta, Sherman Mark E, Peplonska Beata, Brinton Louise A, Healey Catherine S, Ahmed Shahana, Pharoah Paul, Easton Douglas, Chanock Stephen, Garcia-Closas Montserr |
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Rare mutations in the PIK3CA gene contribute to aggressive endometrial cancer.
DNA and cell biology 2010 Feb 29 (2): 65-70. Konstantinova Darina, Kaneva Radka, Dimitrov Roumen, Savov Alexey, Ivanov Stephan, Dyankova Tzvetanka, Kremensky Ivo, Mitev Van |
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The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type.
Journal of experimental & clinical cancer research : CR 2010 29 (1): 32. Barbi Stefano, Cataldo Ivana, De Manzoni Giovanni, Bersani Samantha, Lamba Simona, Mattuzzi Silvia, Bardelli Alberto, Scarpa Al |
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Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 106 (12): 4834-9. Salvesen H B, Carter S L, Mannelqvist M, Dutt A, Getz G, Stefansson I M, Raeder M B, Sos M L, Engelsen I B, Trovik J, Wik E, Greulich H, Bø T H, Jonassen I, Thomas R K, Zander T, Garraway L A, Oyan A M, Sellers W R, Kalland K H, Meyerson M, Akslen L A, Beroukhim |
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- Page last updated:Jan 19, 2021
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