HuGE Literature Finder
Records 1-30
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CT texture analysis for the prediction of KRAS mutation status in colorectal cancer via a machine learning approach.
European journal of radiology 2019 Sep 118 38-43. Taguchi Narumi, Oda Seitaro, Yokota Yasuhiro, Yamamura Sadahiro, Imuta Masanori, Tsuchigame Tadatoshi, Nagayama Yasunori, Kidoh Masafumi, Nakaura Takeshi, Shiraishi Shinya, Funama Yoshinori, Shinriki Satoru, Miyamoto Yuji, Baba Hideo, Yamashita Yasuyu |
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G12V and G12C mutations in the gene KRAS are associated with a poorer prognosis in primary colorectal cancer.
International journal of colorectal disease 2019 Aug 34 (8): 1491-1496. Hayama Tamuro, Hashiguchi Yojiro, Okamoto Koichi, Okada Yuka, Ono Kohei, Shimada Ryu, Ozawa Tsuyoshi, Toyoda Tetsutaka, Tsuchiya Takeshi, Iinuma Hisae, Nozawa Keijiro, Matsuda Kei |
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Histologic features and genomic alterations of primary colorectal adenocarcinoma predict growth patterns of liver metastasis.
World journal of gastroenterology 2019 Jul 25 (26): 3408-3425. Wu Jing-Bo, Sarmiento Ali Lopez, Fiset Pierre-Olivier, Lazaris Anthula, Metrakos Peter, Petrillo Stephanie, Gao Zu-H |
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Necessity of Genetic Evaluation of Metachronous Metastases of Colorectal Cancer: Quantitative Analysis of Genetic Discordance Between Metachronous Metastases and Radically Resected Primary Colorectal Cancers Using Next-Generation Sequencing.
Diseases of the colon and rectum 2019 Jul 62 (7): 832-839. Lee Kyung Ha, Kim Jin Soo, Kim Ji Ye |
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Analysis of KRAS, NRAS, BRAF, PIK3CA and TP53 mutations in a large prospective series of locally advanced rectal cancer patients.
International journal of cancer 2019 Jun . Sclafani Francesco, Hulkki Wilson Sanna, Cunningham David, Gonzalez De Castro David, Kalaitzaki Eleftheria, Begum Ruwaida, Wotherspoon Andrew, Capdevila Jaume, Glimelius Bengt, Roselló Susana, Thomas Janet, Tait Daina, Brown Gina, Oates Jacqui, Chau I |
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ARID3A Positivity Correlated With Favorable Prognosis in Patients With Residual Rectal Cancer After Neoadjuvant Chemoradiotherapy.
Anticancer research 2019 Jun 39 (6): 2845-2853. Yoon Ghilsuk, Park Jee Young, Kim Hye Jin, Choi Gyu Seog, Kim Jong Gwang, Kang Byung Woog, Kang Min Kyu, Seo An |
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Clinicopathologic features and prognostic value of KRAS, NRAS, and BRAF mutations and DNA mismatch repair status: a single-center retrospective study of 1834 Chinese patients with stage I-IV colorectal cancer.
International journal of cancer 2019 Jun . Guo Tian-An, Wu Yu-Chen, Tan Cong, Jin Yu-Tong, Sheng Wei-Qi, Cai San-Jun, Liu Fang-Qi, Xu |
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Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer.
BMC cancer 2019 Jun 19 (1): 644. Cavagnari Mariana Abe Vicente, Silva Tiago Donizetti, Pereira Marco Antonio Haddad, Sauer Luísa Jacques, Shigueoka David, Saad Sarhan Sydney, Barão Katia, Ribeiro Carla Caroline Dias, Forones Nora Manouki |
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[Combined detection of KRAS, NRAS, BRAF and PIK3CA mutations in the plasma and tumor tissues of colorectal cancer patients].
Zhonghua bing li xue za zhi = Chinese journal of pathology 2019 May 48 (5): 373-377. Liu X N, Tian Z, Wei X F, Wang Q, Zhang J X, Jin M S, Duan X |
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Dietary intake of fiber, whole grains and risk of colorectal cancer: an updated analysis according to food sources, tumor location and molecular subtypes in two large US cohorts.
International journal of cancer 2019 May . He Xiaosheng, Wu Kana, Zhang Xuehong, Nishihara Reiko, Cao Yin, Fuchs Charlie S, Giovannucci Edward L, Ogino Shuji, Chan Andrew T, Song Mingya |
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Targeted next generation sequencing reveals a common genetic pathway for colorectal cancers with chromosomal instability and those with microsatellite and chromosome stability.
Pathology, research and practice 2019 May 152445. Ham-Karim Hersh A, Ebili Henry O, Bradshaw Kirsty, Richman Susan D, Fadhil Wakkas, Domingo Enric, Tomlinson Ian, Ilyas Mohamm |
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Long non-coding RNA polymorphisms and prediction of response to chemotherapy based on irinotecan in patients with metastatic colorectal cancer.
Cancer biomarkers : section A of Disease markers 2019 Apr . Lampropoulou Dimitra-Ioanna, Aravantinos Gerasimos, Katifelis Hector, Lazaris Foivos, Laschos Konstantinos, Theodosopoulos Theodosios, Papadimitriou Christos, Gazouli Mar |
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Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer: Two case reports.
Medicine 2019 Mar 98 (12): e14781. Okada Satoshi, Hata Keisuke, Kawai Kazushige, Yamamoto Yoko, Tanaka Toshiaki, Nishikawa Takeshi, Sasaki Kazuhito, Kaneko Manabu, Emoto Shigenobu, Murono Koji, Nozawa Hiroa |
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Clinicopathological and molecular differences in colorectal cancer according to location.
The International journal of biological markers 2019 Mar 1724600818807164. Hsu Yu-Lun, Lin Chun-Chi, Jiang Jeng-Kai, Lin Hung-Hsin, Lan Yuan-Tzu, Wang Huann-Sheng, Yang Shung-Haur, Chen Wei-Shone, Lin Tzu-Chen, Lin Jen-Kou, Lin Pei-Ching, Chang Shih-Chi |
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EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.
Histopathology 2019 Mar . Hashimoto Taiki, Ogawa Reiko, Yoshida Hiroshi, Taniguchi Hirokazu, Kojima Motohiro, Saito Yutaka, Sekine Shige |
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Impact of primary colorectal Cancer location on the KRAS status and its prognostic value.
BMC gastroenterology 2019 Mar 19 (1): 46. Xie Ming-Zhi, Li Ji-Lin, Cai Zheng-Min, Li Ke-Zhi, Hu Bang- |
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Loss of LKB1 Protein Expression Correlates with Increased Risk of Recurrence and Death in Patients with Resected, Stage II or III Colon Cancer.
Cancer research and treatment : official journal of Korean Cancer Association 2019 Mar . Sfakianaki Maria, Papadaki Chara, Tzardi Maria, Trypaki Maria, Alam Sardar, Lagoudaki Eleni D, Messaritakis Ippokratis, Zoras Odysseas, Mavroudis Dimitris, Georgoulias Vassilis, Souglakos Jo |
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Biomarker analysis beyond angiogenesis: RAS/RAF mutation status, tumour sidedness, and second-line ramucirumab efficacy in patients with metastatic colorectal carcinoma from RAISE-a global phase III study.
Annals of oncology : official journal of the European Society for Medical Oncology 2019 Jan 30 (1): 124-131. Yoshino T, Portnoy D C, Obermannová R, Bodoky G, Prausová J, Garcia-Carbonero R, Ciuleanu T, García-Alfonso P, Cohn A L, Van Cutsem E, Yamazaki K, Lonardi S, Muro K, Kim T W, Yamaguchi K, Grothey A, O'Connor J, Taieb J, Wijayawardana S R, Hozak R R, Nasroulah F, Tabernero |
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Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.
Cancer medicine 2019 Jan 8 (1): 408-417. Osumi Hiroki, Shinozaki Eiji, Takeda Yoshinori, Wakatsuki Takeru, Ichimura Takashi, Saiura Akio, Yamaguchi Kensei, Takahashi Shunji, Noda Tetsuo, Zembutsu Hitos |
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Demographic trends and KRAS/BRAF
International journal of cancer 2019 05 144 (9): 2109-2117. Fu Xinhui, Huang Yan, Fan Xinjuan, Deng Yanhong, Liu Huanliang, Zou Hongzhi, Wu Peihuang, Chen Zhiting, Huang Jinglin, Wang Jingxuan, Lin Hanjie, Huang Shuhui, Tan Xiaoli, Lan Ping, Wang Lei, Wang Jian-Pi |
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Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes.
PloS one 2019 14 (2): e0211477. Hirano Daiki, Urabe Yuji, Tanaka Shinji, Nakamura Koki, Ninomiya Yuki, Yuge Ryo, Hayashi Ryohei, Oka Shiro, Kitadai Yasuhiko, Shimamoto Fumio, Arihiro Koji, Chayama Kazua |
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High Frequency of KRAS Codon 146 and FBXW7 Mutations in Thai Patients with Stage II-III Colon Cancer.
Asian Pacific journal of cancer prevention : APJCP 2019 08 20 (8): 2319-2326. Korphaisarn Krittiya, Pongpaibul Ananya, Roothumnong Ekkapong, Pongsuktavorn Khontawan, Thamlikitkul Lucksamon, Anekpuritanang Tauangtham, Poungvarin Naravat, Thongnoppakhun Wanna, Pithukpakorn Man |
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Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Journal of clinical pathology 2019 03 72 (3): 263-264. Susanti Susanti, Fadhil Wakkas, Murtaza Shamayal, Hassall James C, Ebili Henry O, Oniscu Anca, Ilyas Mohamm |
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Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.
British journal of cancer 2018 Nov 119 (10): 1244-1251. Trinh Anne, Lädrach Claudia, Dawson Heather E, Ten Hoorn Sanne, Kuppen Peter J K, Reimers Marlies S, Koopman Miriam, Punt Cornelis J A, Lugli Alessandro, Vermeulen Louis, Zlobec In |
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Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer.
Cancer medicine 2018 Oct . Shepshelovich Daniel, Townsend Amanda R, Espin-Garcia Osvaldo, Latifovic Lidija, O'Callaghan Chris J, Jonker Derek J, Tu Dongsheng, Chen Eric, Morgen Eric, Price Timothy J, Shapiro Jeremy, Siu Lillian L, Kubo Michiaki, Dobrovic Alexander, Ratain Mark J, Xu Wei, Mushiroda Taisei, Liu Geoffr |
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Kras-mutation influences outcomes for palliative primary tumor resection in advanced colorectal cancer-a Turkish Oncology Group study.
Surgical oncology 2018 Sep 27 (3): 485-489. Korkmaz Levent, Co?kun Hasan ?enol, Dane Faysal, Karabulut Bülent, Karaa?aç Mustafa, Çabuk Devrim, Karabulut Senem, Aykan Nuri Faruk, Doruk Hatice, Avc? Nilüfer, Turhal Naz?m Serdar, Artaç Mehm |
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RAS-expanded Mutations and HER2 Expression in Metastatic Colorectal Cancer: A New Step of Precision Medicine.
Applied immunohistochemistry & molecular morphology : AIMM 2018 Sep 26 (8): 539-544. Valentini Anna M, Cavalcanti Elisabetta, Di Maggio Marianna, Caruso Maria |
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Acquisition of WNT Pathway Gene Alterations Coincides With the Transition From Precursor Polyps to Traditional Serrated Adenomas.
The American journal of surgical pathology 2018 Aug . Hashimoto Taiki, Ogawa Reiko, Yoshida Hiroshi, Taniguchi Hirokazu, Kojima Motohiro, Saito Yutaka, Sekine Shige |
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Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer.
International journal of cancer 2018 Aug . Eilertsen Ina A, Sveen Anita, Strømme Jonas M, Skotheim Rolf I, Nesbakken Arild, Lothe Ragnhild |
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Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2018 Aug . Wojas-Krawczyk Kamila, Kalinka-Warzocha Ewa, Reszka Katarzyna, Nico? Marcin, Szumi?o Justyna, Ma?dziuk S?awomir, Szczepaniak Katarzyna, Kupnicka Dorota, Lewandowski Remigiusz, Milanowski Janusz, Krawczyk Paw |
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Anti-EGF Receptor-Based Conversion Chemotherapy in RAS Wild-Type Colorectal Cancer Patients: Impact on Survival and Resection Rates.
Digestion 2018 Aug 98 (4): 263-269. Koch Christine, Schmidt Niklas, Winkelmann Ria, Eichler Katrin, Pession Ursula, Bechstein Wolf Otto, Zeuzem Stefan, Waidmann Oliver, Trojan Jö |
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Prognostic significance of CEACAM5mRNA-positive circulating tumor cells in patients with metastatic colorectal cancer.
Cancer chemotherapy and pharmacology 2018 Aug . Messaritakis Ippokratis, Sfakianaki Maria, Papadaki Chara, Koulouridi Asimina, Vardakis Nikolaos, Koinis Filippos, Hatzidaki Dora, Georgoulia Nefeli, Kladi Athina, Kotsakis Athanasios, Souglakos John, Georgoulias Vassil |
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Protocadherin gamma A7 is down-regulated in colorectal cancer and associated with the prognosis in patients with wild-type KRAS.
Human pathology 2018 Aug . Liu Yingdi, Peng Kangsheng, Xie Ruting, Zheng Jiayi, Guo Jing, Wei Rong, Yang Huiqiong, Cai Chunmiao, Wei Qi |
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The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Journal of cancer research and clinical oncology 2018 Aug . Zou Shuang-Mei, Li Wei-Hua, Wang Wen-Miao, Li Wen-Bin, Shi Su-Sheng, Ying Jian-Ming, Lyu Ni |
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Clinical validation of the next-generation sequencing-based Extended RAS Panel assay using metastatic colorectal cancer patient samples from the phase 3 PRIME study.
Journal of cancer research and clinical oncology 2018 Jul . Udar Nitin, Lofton-Day Catherine, Dong Jun, Vavrek Darcy, Jung A Scott, Meier Kristen, Iyer Anita, Slaughter Ryan, Gutekunst Karen, Bach Bruce A, Peeters Marc, Douillard Jean-Yv |
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HER2 status in patients with residual rectal cancer after preoperative chemoradiotherapy: the relationship with molecular results and clinicopathologic features.
Virchows Archiv : an international journal of pathology 2018 Jul . Park Jun Seok, Yoon Ghilsuk, Kim Hye Jin, Park Soo Yeun, Choi Gyu Seog, Kang Min Kyu, Kim Jong Gwang, Jang Jung-Sik, Seo An |
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Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Clinical colorectal cancer 2018 Jul . Khan Maliha, Loree Jonathan M, Advani Shailesh M, Ning Jing, Li Wen, Pereira Allan A L, Lam Michael, Raghav Kanwal, Morris Van K, Broaddus Russell, Maru Dipen, Overman Michael J, Kopetz Sco |
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Randomized Phase II Trial of CapOX plus Bevacizumab and CapIRI plus Bevacizumab as First-Line Treatment for Japanese Patients with Metastatic Colorectal Cancer (CCOG-1201 Study).
The oncologist 2018 Jul . Nakayama Goro, Mitsuma Ayako, Sunagawa Yuki, Ishigure Kiyoshi, Yokoyama Hiroyuki, Matsui Takanori, Nakayama Hiroshi, Nakata Kazuhiko, Ishiyama Akiharu, Asada Takahiro, Umeda Shinichi, Ezaka Kazuhiro, Hattori Norifumi, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhi |
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The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern.
Acta oncologica (Stockholm, Sweden) 2018 Jul 1-7. Prasanna Thiru, Karapetis Christos S, Roder David, Tie Jeanne, Padbury Robert, Price Timothy, Wong Rachel, Shapiro Jeremy, Nott Louise, Lee Margaret, Chua Yu Jo, Craft Paul, Piantadosi Cynthia, Sorich Michael, Gibbs Peter, Yip Desmo |
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Urinary measurement of circulating tumor DNA for treatment monitoring and prognosis of metastatic colorectal cancer patients.
Clinical chemistry and laboratory medicine 2018 Jul . Song Tao, Mao Fei, Shi Li, Xu Xuemei, Wu Zirong, Zhou Juan, Xiao Meifa |
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Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Scientific reports 2018 Jun 8 (1): 9204. Fritsche-Guenther Raphaela, Zasada Christin, Mastrobuoni Guido, Royla Nadine, Rainer Roman, Roßner Florian, Pietzke Matthias, Klipp Edda, Sers Christine, Kempa Stef |
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First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Clinical drug investigation 2018 Jun 38 (6): 553-562. Moiseyenko Vladimir M, Moiseyenko Fedor V, Yanus Grigoriy A, Kuligina Ekatherina Sh, Sokolenko Anna P, Bizin Ilya V, Kudriavtsev Alexey A, Aleksakhina Svetlana N, Volkov Nikita M, Chubenko Vyacheslav A, Kozyreva Kseniya S, Kramchaninov Mikhail M, Zhuravlev Alexandr S, Shelekhova Kseniya V, Pashkov Denis V, Ivantsov Alexandr O, Venina Aigul R, Sokolova Tatyana N, Preobrazhenskaya Elena V, Mitiushkina Natalia V, Togo Alexandr V, Iyevleva Aglaya G, Imyanitov Evgeny |
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Metabolic Imaging Phenotype Using Radiomics of [ 18 F]FDG PET/CT Associated with Genetic Alterations of Colorectal Cancer.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2018 Jun . Chen Shang-Wen, Shen Wei-Chih, Chen William Tzu-Liang, Hsieh Te-Chun, Yen Kuo-Yang, Chang Jan-Gowth, Kao Chia-Hu |
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Multi-center evaluation of the Idylla™ NRAS-BRAF Mutation Test in metastatic colorectal cancer.
The Journal of molecular diagnostics : JMD 2018 Jun . Prieto-Potin Iván, Montagut Clara, Bellosillo Beatriz, Evans Matthew, Smith Matthew, Melchior Linea, Reiltin Werner, Bennett Michael, Pennati Veronica, Castiglione Francesca, Bürrig Karl-Friedrich, Cooper Ulrike, Dockhorn-Dworniczak Barbara, Rossenbach Christiana, Luna-Aguirre Claudia Maribel, Barrera-Saldaña Hugo Alberto, Machado José Carlos, Costa José Luis, Yacobi Rinat, Tabibian-Keissar Hilla, Buglioni Simonetta, Ronchetti Livia, Douglas-Berger Lotte, Dubbink Hendrikus Jan, Alorini Mohammed, Sabourin Jean-Christophe, Rojo Federi |
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Phase II Trial of Biweekly Cetuximab and Irinotecan as Third-Line Therapy for Pretreated KRAS Exon 2 Wild-Type Colorectal Cancer.
Cancer science 2018 Jun . Osumi Hiroki, Shinozaki Eiji, Mashima Tetsuo, Wakatsuki Takeru, Suenaga Mitsukuni, Ichimura Takashi, Ogura Mariko, Ota Yumiko, Nakayama Izuma, Takahari Daisuke, Chin Keisho, Miki Yoshio, Yamaguchi Kens |
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Predictive factors of synchronous colorectal peritoneal metastases: Development of a nomogram and study of its utilities using decision curve analysis.
International journal of surgery (London, England) 2018 Jun 54 (Pt A): 149-155. Mo Shaobo, Dai Weixing, Xiang Wenqiang, Li Qingguo, Wang Renjie, Cai Guoxia |
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Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
JAMA surgery 2018 May e180996. Margonis Georgios Antonios, Buettner Stefan, Andreatos Nikolaos, Kim Yuhree, Wagner Doris, Sasaki Kazunari, Beer Andrea, Schwarz Christoph, Løes Inger Marie, Smolle Maria, Kamphues Carsten, He Jin, Pawlik Timothy M, Kaczirek Klaus, Poultsides George, Lønning Per Eystein, Cameron John L, Burkhart Richard A, Gerger Armin, Aucejo Federico N, Kreis Martin E, Wolfgang Christopher L, Weiss Matthew |
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Clinicopathological and molecular differences between right-sided and left-sided colorectal cancer in Japanese patients.
Japanese journal of clinical oncology 2018 May . Natsume Soichiro, Yamaguchi Tatsuro, Takao Misato, Iijima Takeru, Wakaume Rika, Takahashi Keiichi, Matsumoto Hiroshi, Nakano Daisuke, Horiguchi Shin-Ichiro, Koizumi Koichi, Miyaki Michi |
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Common KRAS and NRAS gene mutations in sporadic colorectal cancer in Northeastern Iranian patients.
Current problems in cancer 2018 May . Hamzehzadeh Leila, Khadangi Fatemeh, Ghayoor Karimiani Ehsan, Pasdar Alireza, Kerachian Mohammad Am |
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Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation.
Inflammatory bowel diseases 2018 May . Hartman Douglas J, Binion David G, Regueiro Miguel D, Miller Caitlyn, Herbst Cameron, Pai Reetesh |
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Immunohistochemical and genetic characteristics of a colorectal mucin-rich variant of traditional serrated adenoma.
Histopathology 2018 May . Hiromoto Takafumi, Murakami Takashi, Akazawa Yoichi, Sasahara Noriko, Saito Tsuyoshi, Sakamoto Naoto, Mitomi Hiroyuki, Nagahara Akihito, Yao Takas |
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Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2018 May (38): 231-238. Dienstmann Rodrigo, Salazar Ramon, Tabernero Jos |
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Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Medical oncology (Northwood, London, England) 2018 May 35 (7): 101. Papaxoinis George, Kotoula Vassiliki, Giannoulatou Eleni, Koliou Georgia-Angeliki, Karavasilis Vasilios, Lakis Sotirios, Koureas Andreas, Bobos Mattheos, Chalaralambous Elpida, Daskalaki Emily, Chatzopoulos Kyriakos, Tsironis George, Pazarli Elisavet, Chrisafi Sofia, Samantas Epaminontas, Kaklamanos Ioannis G, Varthalitis Ioannis, Konstantara Athina, Syrigos Konstantinos N, Pentheroudakis George, Pectasides Dimitrios, Fountzilas Geor |
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Is primary sidedness a prognostic factor in patients with resected colon cancer liver metastases (CLM)?
Journal of surgical oncology 2018 Apr . Marques Márcio C, C Ribeiro Héber S, Costa Wílson L, de Jesus Victor Hugo F, de Macedo Mariana P, Diniz Alessandro L, Godoy André L, Farias Igor C, Aguiar Samuel, Riechelmann Rachel S P, S Begnami Maria Dirlei F, Coimbra Felipe J |
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KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
Human pathology 2018 Apr 74 178-182. Tessitore Alessandra, Bruera Gemma, Mastroiaco Valentina, Cannita Katia, Cortellini Alessio, Cocciolone Valentina, Dal Mas Antonella, Calvisi Giuseppe, Zazzeroni Francesca, Ficorella Corrado, Ricevuto Enrico, Alesse Edoar |
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Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Journal of the National Cancer Institute 2018 Apr . Loree Jonathan M, Bailey Ann M, Johnson Amber M, Yu Yao, Wu Wenhui, Bristow Christopher A, Davis Jennifer S, Shaw Kenna R, Broaddus Russell, Banks Kimberly C, Lanman Richard B, Meric-Bernstam Funda, Overman Michael J, Kopetz Scott, Raghav Kanw |
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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.
Scientific reports 2018 Apr 8 (1): 6076. Guo Fang, Gong Hai, Zhao Huanhuan, Chen Jing, Zhang Yiming, Zhang Lihua, Shi Xin, Zhang Aifeng, Jin Hui, Zhang Jianqiong, He You |
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Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Virchows Archiv : an international journal of pathology 2018 Apr . Wang Yajian, Liu Haijing, Hou Yingyong, Zhou Xiaoyan, Liang Li, Zhang Zhihong, Shi Huaiyin, Xu Sanpeng, Hu Peizhen, Zheng Zuyu, Liu Rui, Tang Tingdong, Ye Feng, Liang Zhiyong, Bu Ho |
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CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Mar . Smeby J, Sveen A, Merok M A, Danielsen S A, Eilertsen I A, Guren M G, Dienstmann R, Nesbakken A, Lothe R |
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Mutation analysis of adenomas and carcinomas of the colon: early and late drivers.
Genes, chromosomes & cancer 2018 Mar . Wolff Roger K, Hoffman Michael D, Wolff Erica C, Herrick Jennifer S, Sakoda Lori C, Samowitz Wade, Slattery Martha |
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Phase II study of the dual EGFR/HER3 inhibitor duligotuzumab (MEHD7945A) vs. cetuximab in combination with FOLFIRI in RAS wild-type metastatic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Mar . Hill Andrew Graham, Findlay Michael, Burge Matthew, Jackson Christopher, García Alfonso Pilar, Samuel Leslie, Ganju Vinod, Karthaus Meinolf, Amatu Alessio, Jeffery Mark, Di Bartolomeo Maria, Bridgewater John, Coveler Andrew L, Hidalgo Manuel, Kapp Amy V, Sufan Roxana, McCall Bruce, Hanley William, Penuel Elicia, Pirzkall Andrea, Tabernero Jos |
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Phenotypic and genotypic differences in colorectal carcinoma among Caucasians, Asians, and Hispanics lack statistical significance.
Pathology, research and practice 2018 Mar . Hoffman Sara J, Wu Mark Li-Che |
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Prognostic value of radiologically enlarged lymph nodes in patients with metastatic colorectal cancer: Subgroup findings of the randomized, open-label FIRE-3/AIO KRK0306 trial.
European journal of radiology 2018 Mar 100 124-129. Hofmann Felix O, Holch Julian W, Heinemann Volker, Ricard Ingrid, Reiser Maximilian F, Baumann Alena B, Hesse Nina, D'Anastasi Melvin, Modest Dominik P, Stintzing Sebastian, Sommer Wieland |
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The Molecular Landscape of Synchronous Colorectal Cancer Reveals Genetic Heterogeneity.
Carcinogenesis 2018 Mar . Wang Xiangfeng, Fang Hu, Cheng Yong, Li Lin, Sun Xiaohui, Fu Tao, Huang Peide, Zhang Anping, Feng Zhimin, Li Chunxue, Huang Xuanlin, Li Guangyan, Du Peina, Yang Huanming, Fang Xiaodong, Li Fan, Gao Qiang, Liu Baoh |
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Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing.
Neoplasia (New York, N.Y.) 2018 Feb 20 (3): 256-262. Shajani-Yi Zahra, de Abreu Francine B, Peterson Jason D, Tsongalis Gregory |
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Phosphorylation of p70 Ribosomal Protein S6 Kinase ?-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.
Clinical colorectal cancer 2018 Feb . Wiesweg Marcel, Reis Henning, Köster Tobias, Goetz Moritz, Worm Karl, Herold Thomas, Paul Andreas, Dechêne Alexander, Schumacher Brigitte, Markus Peter, Virchow Isabel, Kostbade Karina, Wolf Nathalie, Zaun Gregor, Metzenmacher Martin, Schmid Kurt W, Schuler Martin, Kasper Stef |
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Prognostic factors in patients with advanced and recurrent colorectal cancer receiving last-line chemotherapy.
Die Pharmazie 2018 Feb 73 (2): 115-119. Kimura M, Iwai M, Usami E, Teramachi H, Yoshimura |
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Spectrum of APC and MUTYH germ-line mutations in Russian patients with colorectal malignancies.
Clinical genetics 2018 Feb . Yanus G A, Akhapkina T A, Ivantsov A O, Preobrazhenskaya E V, Aleksakhina S N, Bizin I V, Sokolenko A P, Mitiushkina N V, Kuligina E S, Suspitsin E N, Venina A R, Holmatov M M, Zaitseva O A, Yatsuk O S, Pashkov D V, Belyaev A M, Togo A V, Imyanitov E N, Iyevleva A |
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Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2018 Jan . Jesinghaus Moritz, Konukiewitz Björn, Foersch Sebastian, Stenzinger Albrecht, Steiger Katja, Muckenhuber Alexander, Groß Claudia, Mollenhauer Martin, Roth Wilfried, Detlefsen Sönke, Weichert Wilko, Klöppel Günter, Pfarr Nicole, Schlitter Anna Melis |
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Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.
Acta oncologica (Stockholm, Sweden) 2018 Jan 1-6. Christensen Troels Dreier, Palshof Jesper Andreas, Larsen Finn Ole, Poulsen Tim Svenstrup, Høgdall Estrid, Pfeiffer Per, Jensen Benny Vittrup, Yilmaz Mette Karen, Nielsen Dor |
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Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer?
European radiology 2018 Jan . Yang Lei, Dong Di, Fang Mengjie, Zhu Yongbei, Zang Yali, Liu Zhenyu, Zhang Hongmei, Ying Jianming, Zhao Xinming, Tian J |
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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Cancer cell 2018 Jan 33 (1): 125-136.e3. Yaeger Rona, Chatila Walid K, Lipsyc Marla D, Hechtman Jaclyn F, Cercek Andrea, Sanchez-Vega Francisco, Jayakumaran Gowtham, Middha Sumit, Zehir Ahmet, Donoghue Mark T A, You Daoqi, Viale Agnes, Kemeny Nancy, Segal Neil H, Stadler Zsofia K, Varghese Anna M, Kundra Ritika, Gao Jianjiong, Syed Aijazuddin, Hyman David M, Vakiani Efsevia, Rosen Neal, Taylor Barry S, Ladanyi Marc, Berger Michael F, Solit David B, Shia Jinru, Saltz Leonard, Schultz Nikola |
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Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.
Sensors (Basel, Switzerland) 2018 Jan 18 (1): . Guarnaccia Maria, Iemmolo Rosario, San Biagio Floriana, Alessi Enrico, Cavallaro Sebastia |
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KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.
Scientific reports 2018 Jan 8 (1): 1445. Sclafani Francesco, Chau Ian, Cunningham David, Hahne Jens C, Vlachogiannis George, Eltahir Zakaria, Lampis Andrea, Braconi Chiara, Kalaitzaki Eleftheria, De Castro David Gonzalez, Wotherspoon Andrew, Capdevila Jaume, Glimelius Bengt, Tarazona Noelia, Begum Ruwaida, Lote Hazel, Hulkki Wilson Sanna, Mentrasti Giulia, Brown Gina, Tait Diana, Oates Jacqueline, Valeri Nico |
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Mutations of key driver genes in colorectal cancer progression and metastasis.
Cancer metastasis reviews 2018 Jan . Huang Dongdong, Sun Wenjie, Zhou Yuwei, Li Peiwei, Chen Fang, Chen Hanwen, Xia Dajing, Xu Enping, Lai Maode, Wu Yihua, Zhang Hong |
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Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Cancer 2018 Jan . Ross Jeffrey S, Fakih Marwan, Ali Siraj M, Elvin Julia A, Schrock Alexa B, Suh James, Vergilio Jo-Anne, Ramkissoon Shakti, Severson Eric, Daniel Sugganth, Fabrizio David, Frampton Garrett, Sun James, Miller Vincent A, Stephens Philip J, Gay Laurie |
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Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Molecular cancer 2018 12 17 (1): 176. Chen Erfei, Yang Fangfang, He Hongjuan, Li Qiqi, Zhang Wei, Xing Jinliang, Zhu Ziqing, Jiang Jingjing, Wang Hua, Zhao Xiaojuan, Liu Ruitao, Lei Lei, Dong Jing, Pei Yuchen, Yang Ying, Pan Junqiang, Zhang Pan, Liu Shuzhen, Du Le, Zeng Yuan, Yang J |
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An Analysis of Relationship Between RAS Mutations and Prognosis of Primary Tumour Resection for Metastatic Colorectal Cancer Patients.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018 50 (2): 768-782. Liang Li, Tian Jiawen, Yu Yiyi, Wang Zhiming, Peng Ke, Liu Ruiqi, Wang Yan, Xu Xiaojing, Li Hong, Zhuang Rongyuan, Cui Yuehong, Zhu Chouwen, Liu Tians |
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Clinical Impact and Prognostic Role of KRAS/BRAF/PIK3CA Mutations in Stage I Colorectal Cancer.
Disease markers 2018 2018 2959801. Reggiani Bonetti Luca, Barresi Valeria, Maiorana Antonino, Manfredini Samantha, Caprera Cecilia, Bettelli Stefan |
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Colorectal cancer molecular classification using BRAF, KRAS, microsatellite instability and CIMP status: Prognostic implications and response to chemotherapy.
PloS one 2018 13 (9): e0203051. Murcia Oscar, Juárez Míriam, Rodríguez-Soler María, Hernández-Illán Eva, Giner-Calabuig Mar, Alustiza Miren, Egoavil Cecilia, Castillejo Adela, Alenda Cristina, Barberá Víctor, Mangas-Sanjuan Carolina, Yuste Ana, Bujanda Luís, Clofent Joan, Andreu Montserrat, Castells Antoni, Llor Xavier, Zapater Pedro, Jover Rodri |
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Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer research 2018 05 38 (5): 2891-2895. Deshwar Amar, Margonis Georgios Antonios, Andreatos Nikolaos, Barbon Carlotta, Wang Jaeyun, Buettner Stefan, Wagner Doris, Sasaki Kazunari, Beer Andrea, Løes Inger Marie, Pikoulis Emmanouil, Damaskos Christos, Garmpis Nikolaos, Kamphues Karsten, He Jin, Kaczirek Klaus, Poultsides George, Lønning Per Eystein, Mischinger Hans Joerg, Aucejo Federico N, Kreis Martin E, Wolfgang Christopher L, Weiss Matthew |
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Evaluation of the detection of Toll-like receptors (TLRs) in cancer development and progression in patients with colorectal cancer.
PloS one 2018 13 (6): e0197327. Messaritakis Ippokratis, Stogiannitsi Maria, Koulouridi Asimina, Sfakianaki Maria, Voutsina Alexandra, Sotiriou Afroditi, Athanasakis Elias, Xynos Evangelos, Mavroudis Dimitris, Tzardi Maria, Souglakos Jo |
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Final Analysis of Outcomes and RAS/BRAF Status in a Randomized Phase 3 Study of Panitumumab and Best Supportive Care in Chemorefractory Wild Type KRAS Metastatic Colorectal Cancer.
Clinical colorectal cancer 2018 09 17 (3): 206-214. Kim Tae Won, Elme Anneli, Park Joon Oh, Udrea Anghel Adrian, Kim Sun Young, Ahn Joong Bae, Valencia Ricardo Villalobos, Krishnan Srinivasan, Manojlovic Nebojsa, Guan Xuesong, Lofton-Day Catherine, Jung A Scott, Vrdoljak Edua |
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KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 01 24 (1): 224-233. Lal Neeraj, White Brian S, Goussous Ghaleb, Pickles Oliver, Mason Mike J, Beggs Andrew D, Taniere Philippe, Willcox Benjamin E, Guinney Justin, Middleton Gary |
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Oncogenic KRAS suppresses store-operated Ca
Cell calcium 2018 06 72 70-80. Pierro Cristina, Zhang Xuexin, Kankeu Cynthia, Trebak Mohamed, Bootman Martin D, Roderick H Llewel |
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One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status.
PloS one 2018 13 (4): e0196233. Myte Robin, Gylling Björn, Häggström Jenny, Schneede Jörn, Löfgren-Burström Anna, Huyghe Jeroen R, Hallmans Göran, Meyer Klaus, Johansson Ingegerd, Ueland Per Magne, Palmqvist Richard, Van Guelpen Betha |
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RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 01 29 (1): 112-118. Normanno N, Esposito Abate R, Lambiase M, Forgione L, Cardone C, Iannaccone A, Sacco A, Rachiglio A M, Martinelli E, Rizzi D, Pisconti S, Biglietto M, Bordonaro R, Troiani T, Latiano T P, Giuliani F, Leo S, Rinaldi A, Maiello E, Ciardiello F, |
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RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients.
Canadian journal of gastroenterology & hepatology 2018 2018 4248971. Yao Jiannan, Zang Wanchun, Ge Yang, Weygant Nathaniel, Yu Pan, Li Lei, Rao Guanhua, Jiang Zhi, Yan Rui, He Linjia, Yu Yang, Jin Mulan, Cheng Gang, An Guang |
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Sidedness and TP53 mutations impact OS in anti-EGFR but not anti-VEGF treated mCRC - an analysis of the KRAS registry of the AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie).
BMC cancer 2018 01 18 (1): 11. Huemer Florian, Thaler Josef, Piringer Gudrun, Hackl Hubert, Pleyer Lisa, Hufnagl Clemens, Weiss Lukas, Greil Richa |
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SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.
BMC cancer 2018 04 18 (1): 479. Mei Zhu, Shao Yang W, Lin Peinan, Cai Xiaomin, Wang Biao, Ding Yan, Ma Xiangyuan, Wu Xue, Xia Yewei, Zhu Dongqin, Shu Yongqian, Fu Zan, Gu Yanho |
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Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon cancer.
The pharmacogenomics journal 2017 Dec . Riera Pau, Virgili Anna C, Salazar Juliana, Sebio Ana, Tobeña María, Sullivan Ivana, Páez Dav |
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Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Molecular carcinogenesis 2017 Dec . Sugai Tamotsu, Takahashi Yayoi, Eizuka Makoto, Sugimoto Ryo, Fujita Yasuko, Habano Wataru, Otsuka Kouki, Sasaki Akira, Yamamoto Eiichiro, Matsumoto Takayuki, Suzuki Hiro |
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Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
British journal of cancer 2017 Dec 117 (12): 1819-1827. Lièvre Astrid, Ouine Bérèngere, Canet Jim, Cartier Aurélie, Amar Yael, Cacheux Wulfran, Mariani Odette, Guimbaud Rosine, Selves Janick, Lecomte Thierry, Guyetant Serge, Bieche Ivan, Berger Frédérique, de Koning Lean |
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Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and are Primed for Neoplastic Progression.
Molecular cancer research : MCR 2017 Dec . Drew David A, Mo Allen, Grady James J, Stevens Richard G, Levine Joel B, Brenner Bruce M, Anderson Joseph C, Forouhar Faripour, O'Brien Michael J, Devers Thomas J, Rosenberg Daniel |
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Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials.
Annals of oncology : official journal of the European Society for Medical Oncology 2017 Nov 28 (11): 2780-2785. Berger M D, Stintzing S, Heinemann V, Yang D, Cao S, Sunakawa Y, Ning Y, Matsusaka S, Okazaki S, Miyamoto Y, Suenaga M, Schirripa M, Soni S, Zhang W, Falcone A, Loupakis F, Lenz H |
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Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer.
BMC gastroenterology 2017 Nov 17 (1): 121. Kim Dalyong, Kim Sun Young, Lee Ji Sung, Hong Yong Sang, Kim Jeong Eun, Kim Kyu-Pyo, Kim Jihun, Jang Se Jin, Yoon Young-Kwang, Kim Tae W |
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The RAS mutation status predicts survival in patients undergoing hepatic resection for colorectal liver metastases: The results from a genetic analysis of all-RAS.
Journal of surgical oncology 2017 Nov . Amikura Katsumi, Akagi Kiwamu, Ogura Toshiro, Takahashi Amane, Sakamoto Hirohi |
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The role of APC in WNT pathway activation in serrated neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Nov . Borowsky Jennifer, Dumenil Troy, Bettington Mark, Pearson Sally-Ann, Bond Catherine, Fennell Lochlan, Liu Cheng, McKeone Diane, Rosty Christophe, Brown Ian, Walker Neal, Leggett Barbara, Whitehall Vic |
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Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas.
Histopathology 2017 Oct 71 (4): 601-609. Sekine Shigeki, Ogawa Reiko, Hashimoto Taiki, Motohiro Kojima, Yoshida Hiroshi, Taniguchi Hirokazu, Saito Yutaka, Yasuhiro Ohno, Ochiai Atsushi, Hiraoka Nobuyos |
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Multicenter analysis of risk factors for anastomotic leakage after middle and low rectal cancer resection without diverting stoma: a retrospective study of 319 consecutive patients.
International journal of colorectal disease 2017 Oct 32 (10): 1431-1437. Zhang Wei, Lou Zheng, Liu Qizhi, Meng Ronggui, Gong Haifeng, Hao Liqiang, Liu Peng, Sun Ge, Ma Jun, Zhang W |
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