HuGE Literature Finder
Records 1-100
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High frequency of H3K27M immunopositivity in adult thalamic glioblastoma.
Neuropathology : official journal of the Japanese Society of Neuropathology 2019 Apr 39 (2): 78-84. Rao Shilpa, Kanuri Nandaki N, Nimbalkar Vidya, Arivazhagan Arimappamagan, Santosh Va |
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The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
Brain pathology (Zurich, Switzerland) 2019 Jan 29 (1): 85-96. Phillips Joanna J, Gong Henry, Chen Katharine, Joseph Nancy M, van Ziffle Jessica, Bastian Boris C, Grenert James P, Kline Cassie N, Mueller Sabine, Banerjee Anuradha, Nicolaides Theodore, Gupta Nalin, Berger Mitchel S, Lee Han S, Pekmezci Melike, Tihan Tarik, Bollen Andrew W, Perry Arie, Shieh Joseph T C, Solomon David |
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Granular cell astrocytoma: an aggressive IDH-wildtype diffuse gliomarwith molecular genetic features of primary glioblastoma.
Brain pathology (Zurich, Switzerland) 2018 Sep . Vizcaino M Adelita, Palsgrove Doreen N, Yuan Ming, Giannini Caterina, Cabrera-Aldana Eibar Ernesto, Pallavajjala Aparna, Burger Peter C, Rodriguez Fausto |
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Molecular Study of Long-Term Survivors of Glioblastoma by Gene-Targeted Next-Generation Sequencing.
Journal of neuropathology and experimental neurology 2018 Aug 77 (8): 710-716. Cantero Diana, Rodríguez de Lope Ángel, Moreno de la Presa Raquel, Sepúlveda Juan M, Borrás José M, Castresana Javier S, D'Haene Nicky, García Juan F, Salmon Isabelle, Mollejo Manuela, Rey Juan A, Hernández-Laín Aurelio, Meléndez Bárba |
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Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity.
JCI insight 2018 Aug 3 (15): . Fischer Nicholas W, Prodeus Aaron, Gariépy Je |
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LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.
Breast cancer research and treatment 2018 Jun . Van Swearingen Amanda E D, Siegel Marni B, Deal Allison M, Sambade Maria J, Hoyle Alan, Hayes D Neil, Jo Heejoon, Little Paul, Dees Elizabeth Claire, Muss Hyman, Jolly Trevor, Zagar Timothy M, Patel Nirali, Miller C Ryan, Parker Joel S, Smith J Keith, Fisher Julie, Shah Nikita, Nabell Lisle, Nanda Rita, Dillon Patrick, Abramson Vandana, Carey Lisa A, Anders Carey |
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IDH-mutated astrocytomas with 19q-loss constitute a subgroup that confers better prognosis.
Cancer science 2018 May . Otani Ryohei, Uzuka Takeo, Higuchi Fumi, Matsuda Hadzki, Nomura Masashi, Tanaka Shota, Mukasa Akitake, Ichimura Koichi, Kim Phyo, Ueki Keisu |
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Mutation profiling of key cancer genes in primary breast cancers and their distant metastases.
Cancer research 2018 Apr . Schrijver Willemijne Ame, Selenica Pier, Lee Ju Youn, Ng Charlotte K Y, Burke Kathleen, Piscuoglio Salvatore, Berman Samuel H, Reis-Filho Jorge S, Weigelt Britta, Van Diest Paul J, Moelans Cathy |
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The clinicopathological and prognostic significance of TP53 alteration in K27M mutated gliomas: an individual-participant data meta-analysis.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2018 Apr . Dong Chengya, Yuan Zhengrong, Li Qi, Wang Yaj |
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Paradoxical prognostic impact of TERT promoter mutations in gliomas depends on different histological and genetic backgrounds.
CNS neuroscience & therapeutics 2017 Oct 23 (10): 790-797. You Hao, Wu Yao, Chang Kai, Shi Xiao, Chen Xin-Da, Yan Wei, Li R |
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IDH mutation status trumps the Pignatti risk score as a prognostic marker in low-grade gliomas.
Journal of neuro-oncology 2017 Sep . Etxaniz Olatz, Carrato Cristina, de Aguirre Itziar, Queralt Cristina, Muñoz Ana, Ramirez José L, Rosell Rafael, Villà Salvador, Diaz Rocio, Estival Ana, Teixidor Pilar, Indacochea Alberto, Ahjal Sara, Vilà Laia, Balañá Car |
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The preliminary radiogenomics association between MR perfusion imaging parameters and genomic biomarkers, and their predictive performance of overall survival in patients with glioblastoma.
Journal of neuro-oncology 2017 Sep . Liu Xiang, Mangla Rajiv, Tian Wei, Qiu Xing, Li Dongmei, Walter Kevin A, Ekholm Sven, Johnson Mahlon |
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High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients.
Experimental & molecular medicine 2017 Apr 49 (4): e317. Cho Sung-Yup, Park Changho, Na Deukchae, Han Jee Yun, Lee Jieun, Park Ok-Kyoung, Zhang Chengsheng, Sung Chang Ohk, Moon Hyo Eun, Kim Yona, Kim Jeong Hoon, Kim Jong Jae, Khang Shin Kwang, Nam Do-Hyun, Choi Jung Won, Suh Yeon-Lim, Kim Dong Gyu, Park Sung Hye, Youn Hyewon, Yun Kyuson, Kim Jong-Il, Lee Charles, Paek Sun Ha, Park Hans |
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Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 2017 30 (5): 361-371. Houdova Megova M, Drábek J, Dwight Z, Trojanec R, Koudeláková V, Vrbková J, Kalita O, Mlcochova S, Rabcanova M, Hajdúch |
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Prediction of genetic subgroups in adult supra tentorial gliomas by pre- and intraoperative parameters.
Journal of neuro-oncology 2016 Nov . Nakae Shunsuke, Murayama Kazuhiro, Sasaki Hikaru, Kumon Masanobu, Nishiyama Yuya, Ohba Shigeo, Adachi Kazuhide, Nagahisa Shinya, Hayashi Takuro, Inamasu Joji, Abe Masato, Hasegawa Mitsuhiro, Hirose Yuic |
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Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.
Oncotarget 2016 Oct 7 (40): 64615-64630. Li Yan-Xi, Shi Zhifeng, Aibaidula Abudumijiti, Chen Hong, Tang Qisheng, Li Kay Ka-Wai, Chung Nellie Yuk-Fei, Chan Danny Tat-Ming, Poon Wai Sang, Mao Ying, Wu Jinsong, Zhou Liangfu, Chan Aden Ka-Yin, Ng Ho-Keu |
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TP53 and CDKN1A mutation analysis in families with Li-Fraumeni and Li-Fraumeni like syndromes.
Familial cancer 2016 Oct . Andrade Raissa Coelho, Dos Santos Anna Claudia Evangelista, de Aguirre Neto Joaquim Caetano, Nevado Julián, Lapunzina Pablo, Vargas Fernando Reg |
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GBM-associated mutations and altered protein expression are more common in young patients.
Oncotarget 2016 Aug . Ferguson Sherise D, Xiu Joanne, Weathers Shiao-Pei, Zhou Shouhao, Kesari Santosh, Weiss Stephanie E, Verhaak Roeland G, Hohl Raymond J, Barger Geoffrey R, Reddy Sandeep K, Heimberger Amy |
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The Correlation Between 1p/19q Codeletion, IDH1 Mutation, p53 Overexpression and Their Prognostic Roles in 41 Turkish Anaplastic Oligodendroglioma Patients.
Turkish neurosurgery 2016 Aug . Hacisalihoglu Payam, Kucukodaci Zafer, Gundogdu Gokcen, Bilgic Bil |
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TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma.
Oncotarget 2016 Jun . Mascelli Samantha, Nozza Paolo, Jones David T W, Colin Carole, Pistorio Angela, Milanaccio Claudia, Ravegnani Marcello, Consales Alessandro, Witt Olaf, Morana Giovanni, Cama Armando, Capra Valeria, Biassoni Roberto, Pfister Stefan M, Figarella-Branger Dominique, Garrè Maria Luisa, Raso Alessand |
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Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.
Journal of neuro-oncology 2016 May 127 (3): 483-92. Ghasimi Soma, Wibom Carl, Dahlin Anna M, Brännström Thomas, Golovleva Irina, Andersson Ulrika, Melin Beatri |
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Immunohistochemistry on IDH 1/2, ATRX, p53 and Ki-67 substitute molecular genetic testing and predict patient prognosis in grade III adult diffuse gliomas.
Brain tumor pathology 2016 Mar . Takano Shingo, Ishikawa Eiichi, Sakamoto Noriaki, Matsuda Masahide, Akutsu Hiroyoshi, Noguchi Masayuki, Kato Yukinari, Yamamoto Tetsuya, Matsumura Aki |
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Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics.
Acta neuropathologica communications 2016 4 (1): 1. Hoffman Lindsey M, DeWire Mariko, Ryall Scott, Buczkowicz Pawel, Leach James, Miles Lili, Ramani Arun, Brudno Michael, Kumar Shiva Senthil, Drissi Rachid, Dexheimer Phillip, Salloum Ralph, Chow Lionel, Hummel Trent, Stevenson Charles, Lu Q Richard, Jones Blaise, Witte David, Aronow Bruce, Hawkins Cynthia E, Fouladi Mary |
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Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2015 Dec . Friedrich Carsten, von Bueren André O, Kolevatova Larissa, Bernreuther Christian, Grob Tobias, Sepulveda-Falla Diego, van den Boom Leander, Westphal Manfred, Simon Ronald, Glatzel Mark |
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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.
Oncotarget 2015 Oct . Lee Ji Yun, Park Kyunghee, Lim Sung Hee, Kim Hae Su, Yoo Kwai Han, Jung Ki Sun, Song Haa-Na, Hong Mineui, Do In-Gu, Ahn TaeJin, Lee Se Kyung, Bae Soo Youn, Kim Seok Won, Lee Jeong Eon, Nam Seok Jin, Kim Duk-Hwan, Jung Hae Hyun, Kim Ji-Yeon, Ahn Jin Seok, Im Young-Hyuck, Park Yeon H |
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ATRX loss in adult supratentorial diffuse astrocytomas correlates with p53 over expression and IDH1 mutation and predicts better outcome in p53 accumulated patients.
Histology and histopathology 2015 Sep 11664. Shao Li-Wei, Pan Yi, Qi Xue-Ling, Li Yong-Xiao, Ma Xiao-Long, Yi Wei-Ning, Zhang Jing, Zhong Yan-Feng, Chang Qi |
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Clinicopathologic implications of NF1 gene alterations in diffuse gliomas.
Human pathology 2015 Sep 46 (9): 1323-30. Vizcaíno M Adelita, Shah Smit, Eberhart Charles G, Rodriguez Fausto |
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Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics.
Oncotarget 2015 Sep . Li Rui, Chen Xincheng, You Yongping, Wang Xiefeng, Liu Yanwei, Hu Qi, Yan W |
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Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.
Neuro-oncology 2015 Sep . Dubbink Hendrikus J, Atmodimedjo Peggy N, Kros Johan M, French Pim J, Sanson Marc, Idbaih Ahmed, Wesseling Pieter, Enting Roelien, Spliet Wim, Tijssen Cees, Dinjens Winand N M, Gorlia Thierry, van den Bent Martin |
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CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma.
Journal of neuro-oncology 2015 Aug . Dahlin Anna M, Hollegaard Mads V, Wibom Carl, Andersson Ulrika, Hougaard David M, Deltour Isabelle, Hjalmars Ulf, Melin Beatri |
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Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas.
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Aug 35 (4): 324-35. Ogura Ryosuke, Tsukamoto Yoshihiro, Natsumeda Manabu, Isogawa Mizuho, Aoki Hiroshi, Kobayashi Tsutomu, Yoshida Seiichi, Okamoto Kouichiro, Takahashi Hitoshi, Fujii Yukihiko, Kakita Akiyos |
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IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas.
Oncotarget 2015 Jul . Leeper Heather E, Caron Alissa A, Decker Paul A, Jenkins Robert B, Lachance Daniel H, Giannini Cateri |
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The H3.3 K27M mutation results in a poorer prognosis in brainstem gliomas than thalamic gliomas in adults.
Human pathology 2015 Jul . Feng Jie, Hao Shuyu, Pan Changcun, Wang Yu, Wu Zhen, Zhang Junting, Yan Hai, Zhang Liwei, Wan Ho |
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Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2015 May 24 (5): 810-6. Wibom Carl, Späth Florentin, Dahlin Anna M, Langseth Hilde, Hovig Eivind, Rajaraman Preetha, Johannesen Tom Børge, Andersson Ulrika, Melin Beatri |
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Association between molecular alterations and tumor location and MRI characteristics in anaplastic gliomas.
Brain tumor pathology 2015 Apr 32 (2): 99-104. Sonoda Yukihiko, Shibahara Ichiyoo, Kawaguchi Tomohiro, Saito Ryuta, Kanamori Masayuki, Watanabe Mika, Suzuki Hiroyoshi, Kumabe Toshihiro, Tominaga Tei |
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Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Jan 21 (1): 184-92. Merino Diana M, Shlien Adam, Villani Anita, Pienkowska Malgorzata, Mack Stephen, Ramaswamy Vijay, Shih David, Tatevossian Ruth, Novokmet Ana, Choufani Sanaa, Dvir Rina, Ben-Arush Myran, Harris Brent T, Hwang Eugene I, Lulla Rishi, Pfister Stefan M, Achatz Maria Isabel, Jabado Nada, Finlay Jonathan L, Weksberg Rosanna, Bouffet Eric, Hawkins Cynthia, Taylor Michael D, Tabori Uri, Ellison David W, Gilbertson Richard J, Malkin Dav |
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Gene mutation profiling of primary glioblastoma through multiple tumor biopsy guided by 1H-magnetic resonance spectroscopy.
International journal of clinical and experimental pathology 2015 8 (5): 5327-35. Tang Chao, Guo Jun, Chen Hong, Yao Cheng-Jun, Zhuang Dong-Xiao, Wang Yin, Tang Wei-Jun, Ren Guang, Yao Yu, Wu Jin-Song, Mao Ying, Zhou Liang- |
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PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas.
PloS one 2015 10 (11): e0142750. Nakae Shunsuke, Sasaki Hikaru, Hayashi Saeko, Hattori Natsuki, Kumon Masanobu, Nishiyama Yuya, Adachi Kazuhide, Nagahisa Shinya, Hayashi Takuro, Inamasu Joji, Abe Masato, Hasegawa Mitsuhiro, Hirose Yuic |
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PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients.
Acta neuropathologica communications 2015 3 (1): 88. Draaisma Kaspar, Wijnenga Maarten M J, Weenink Bas, Gao Ya, Smid Marcel, Robe P, van den Bent Martin J, French Pim |
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Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors.
Acta neuropathologica 2014 Dec 128 (6): 853-62. Mangerel Joshua, Price Aryeh, Castelo-Branco Pedro, Brzezinski Jack, Buczkowicz Pawel, Rakopoulos Patricia, Merino Diana, Baskin Berivan, Wasserman Jonathan, Mistry Matthew, Barszczyk Mark, Picard Daniel, Mack Stephen, Remke Marc, Starkman Hava, Elizabeth Cynthia, Zhang Cindy, Alon Noa, Lees Jodi, Andrulis Irene L, Wunder Jay S, Jabado Nada, Johnston Donna L, Rutka James T, Dirks Peter B, Bouffet Eric, Taylor Michael D, Huang Annie, Malkin David, Hawkins Cynthia, Tabori U |
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Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
Nature genetics 2014 Jul 46 (7): 726-30. Zhang Liwei, Chen Lee H, Wan Hong, Yang Rui, Wang Zhaohui, Feng Jie, Yang Shaohua, Jones Siân, Wang Sizhen, Zhou Weixin, Zhu Huishan, Killela Patrick J, Zhang Junting, Wu Zhen, Li Guilin, Hao Shuyu, Wang Yu, Webb Joseph B, Friedman Henry S, Friedman Allan H, McLendon Roger E, He Yiping, Reitman Zachary J, Bigner Darell D, Yan H |
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Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2014 Jun 68 (5): 521-6. Stankovic Tijana, Milinkovic Vedrana, Bankovic Jasna, Dinic Jelena, Tanic Nasta, Dramicanin Tatjana, Tanic Niko |
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Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jun 20 (11): 2898-909. Wakimoto Hiroaki, Tanaka Shota, Curry William T, Loebel Franziska, Zhao Dan, Tateishi Kensuke, Chen Juxiang, Klofas Lindsay K, Lelic Nina, Kim James C, Dias-Santagata Dora, Ellisen Leif W, Borger Darrell R, Fendt Sarah-Maria, Vander Heiden Matthew G, Batchelor Tracy T, Iafrate A John, Cahill Daniel P, Chi Andrew |
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TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas.
Journal of neuro-oncology 2014 May 118 (1): 131-9. Gillet Emeline, Alentorn Agusti, Doukouré Brahima, Mundwiller Emeline, van Thuijl Hinke F, van Thuij Hinke, Reijneveld Jaap C, Medina José Alfonso Meza, Liou Amélie, Marie Yannick, Mokhtari Karima, Hoang-Xuan Khê, Sanson Marc, Delattre Jean-Yves, Idbaih Ahm |
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The effects of p53 Arg72Pro polymorphism on glioma susceptibility: a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Apr 35 (4): 3725-30. Zhu Weijie, Lu Lei, Li Yi, Yao Jie, Xu Bain |
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Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
Cancer cell 2014 Mar 25 (3): 393-405. Kool Marcel, Jones David T W, Jäger Natalie, Northcott Paul A, Pugh Trevor J, Hovestadt Volker, Piro Rosario M, Esparza L Adriana, Markant Shirley L, Remke Marc, Milde Till, Bourdeaut Franck, Ryzhova Marina, Sturm Dominik, Pfaff Elke, Stark Sebastian, Hutter Sonja, Seker-Cin Huriye, Johann Pascal, Bender Sebastian, Schmidt Christin, Rausch Tobias, Shih David, Reimand Jüri, Sieber Laura, Wittmann Andrea, Linke Linda, Witt Hendrik, Weber Ursula D, Zapatka Marc, König Rainer, Beroukhim Rameen, Bergthold Guillaume, van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, Schmidt Sabine, Wolf Stephan, Lawerenz Chris, Bartholomae Cynthia C, von Kalle Christof, Unterberg Andreas, Herold-Mende Christel, Hofer Silvia, Kulozik Andreas E, von Deimling Andreas, Scheurlen Wolfram, Felsberg Jörg, Reifenberger Guido, Hasselblatt Martin, Crawford John R, Grant Gerald A, Jabado Nada, Perry Arie, Cowdrey Cynthia, Croul Sydney, Zadeh Gelareh, Korbel Jan O, Doz Francois, Delattre Olivier, Bader Gary D, McCabe Martin G, Collins V Peter, Kieran Mark W, Cho Yoon-Jae, Pomeroy Scott L, Witt Olaf, Brors Benedikt, Taylor Michael D, Schüller Ulrich, Korshunov Andrey, Eils Roland, Wechsler-Reya Robert J, Lichter Peter, Pfister Stefan M, |
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H3F3A K27M mutations in thalamic gliomas from young adult patients.
Neuro-oncology 2014 Jan 16 (1): 140-6. Aihara Koki, Mukasa Akitake, Gotoh Kengo, Saito Kuniaki, Nagae Genta, Tsuji Shingo, Tatsuno Kenji, Yamamoto Shogo, Takayanagi Shunsaku, Narita Yoshitaka, Shibui Soichiro, Aburatani Hiroyuki, Saito Nobuhi |
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Quantitative assessment of the association between TP53 Arg72Pro polymorphism and risk of glioma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Jan 35 (1): 747-51. Zhang Feng, Li Danni, Li Yanshuang, Li Haixia, Sun Jinbo, Li Xianfeng, Li Xiaoho |
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IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.
BioMed research international 2014 2014 654727. Stancheva Gergana, Goranova Teodora, Laleva Maria, Kamenova Margarita, Mitkova Atanaska, Velinov Nikolay, Poptodorov George, Mitev Vanio, Kaneva Radka, Gabrovsky Nikol |
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Prognostic value of MGMT promoter methylation and TP53 mutation in glioblastomas depends on IDH1 mutation.
Asian Pacific journal of cancer prevention : APJCP 2014 15 (24): 10893-8. Wang Kai, Wang Yin-Yan, Ma Jun, Wang Jiang-Fei, Li Shao-Wu, Jiang Tao, Dai Jian-Pi |
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Li-Fraumeni and Li-Fraumeni-like syndrome among children diagnosed with pediatric cancer in Southern Brazil.
Cancer 2013 Dec 119 (24): 4341-9. Giacomazzi Juliana, Selistre Simone G, Rossi Cristina, Alemar Barbara, Santos-Silva Patricia, Pereira Fernando S, Netto Cristina B, Cossio Silvia L, Roth Daniela E, Brunetto Algemir L, Zagonel-Oliveira Marcelo, Martel-Planche Ghyslaine, Goldim Jose R, Hainaut Pierre, Camey Suzi A, Ashton-Prolla Patric |
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TERT promoter mutations in primary and secondary glioblastomas.
Acta neuropathologica 2013 Dec 126 (6): 931-7. Nonoguchi Naosuke, Ohta Takashi, Oh Ji-Eun, Kim Young-Ho, Kleihues Paul, Ohgaki Hiro |
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P53 codon 72 Arg/Pro polymorphism and glioma risk: an updated meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Oct 34 (5): 3121-30. He Fang, Xia Yi, Liu Huafeng, Li Jin, Wang Ch |
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Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Sep 19 (18): 5146-57. Hartmann Christian, Hentschel Bettina, Simon Matthias, Westphal Manfred, Schackert Gabriele, Tonn Jörg C, Loeffler Markus, Reifenberger Guido, Pietsch Torsten, von Deimling Andreas, Weller Michael, |
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Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Aug 31 (23): 2927-35. Zhukova Nataliya, Ramaswamy Vijay, Remke Marc, Pfaff Elke, Shih David J H, Martin Dianna C, Castelo-Branco Pedro, Baskin Berivan, Ray Peter N, Bouffet Eric, von Bueren André O, Jones David T W, Northcott Paul A, Kool Marcel, Sturm Dominik, Pugh Trevor J, Pomeroy Scott L, Cho Yoon-Jae, Pietsch Torsten, Gessi Marco, Rutkowski Stefan, Bognar Laszlo, Klekner Almos, Cho Byung-Kyu, Kim Seung-Ki, Wang Kyu-Chang, Eberhart Charles G, Fevre-Montange Michelle, Fouladi Maryam, French Pim J, Kros Max, Grajkowska Wieslawa A, Gupta Nalin, Weiss William A, Hauser Peter, Jabado Nada, Jouvet Anne, Jung Shin, Kumabe Toshihiro, Lach Boleslaw, Leonard Jeffrey R, Rubin Joshua B, Liau Linda M, Massimi Luca, Pollack Ian F, Shin Ra Young, Van Meir Erwin G, Zitterbart Karel, Schüller Ulrich, Hill Rebecca M, Lindsey Janet C, Schwalbe Ed C, Bailey Simon, Ellison David W, Hawkins Cynthia, Malkin David, Clifford Steven C, Korshunov Andrey, Pfister Stefan, Taylor Michael D, Tabori U |
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Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas.
Oncogene 2013 Jun 32 (25): 3091-100. Wang P, Dong Q, Zhang C, Kuan P-F, Liu Y, Jeck W R, Andersen J B, Jiang W, Savich G L, Tan T-X, Auman J T, Hoskins J M, Misher A D, Moser C D, Yourstone S M, Kim J W, Cibulskis K, Getz G, Hunt H V, Thorgeirsson S S, Roberts L R, Ye D, Guan K-L, Xiong Y, Qin L-X, Chiang D |
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Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.
British journal of cancer 2013 May 108 (10): 2178-85. Enciso-Mora V, Hosking F J, Di Stefano A L, Zelenika D, Shete S, Broderick P, Idbaih A, Delattre J-Y, Hoang-Xuan K, Marie Y, Labussière M, Alentorn A, Ciccarino P, Rossetto M, Armstrong G, Liu Y, Gousias K, Schramm J, Lau C, Hepworth S J, Schoemaker M, Strauch K, Müller-Nurasyid M, Schreiber S, Franke A, Moebus S, Eisele L, Swerdlow A, Simon M, Bondy M, Lathrop M, Sanson M, Houlston R |
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TP53 and RPA3 gene variations were associated with risk of glioma in a Chinese Han population.
Cancer biotherapy & radiopharmaceuticals 2013 Apr 28 (3): 248-53. Jin Tianbo, Zhang Jiayi, Li Gang, Li Shanqu, Yang Bo, Chen Chao, Cai Lin |
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Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients.
Journal of molecular neuroscience : MN 2013 Mar 49 (3): 567-73. Hilmani Said, Abidi Omar, Benrahma Houda, Karkouri Mehdi, Sahraoui Souha, El Azhari Abdessamad, Barakat Abdelham |
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CDKN2A deletion in pediatric versus adult glioblastomas and predictive value of p16 immunohistochemistry.
Neuropathology : official journal of the Japanese Society of Neuropathology 2013 Jan . Purkait S, Jha P, Sharma MC, Suri V, Sharma M, Kale SS, Sarkar C |
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Promoter hypermethylation of the EMP3 gene in a series of 229 human gliomas.
BioMed research international 2013 2013 756302. Mellai Marta, Piazzi Angela, Caldera Valentina, Annovazzi Laura, Monzeglio Oriana, Senetta Rebecca, Cassoni Paola, Schiffer Davi |
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Screening for EGFR amplifications with a novel method and their significance for the outcome of glioblastoma patients.
PloS one 2013 8 (6): e65444. Bie?kowski Micha?, Piaskowski Sylwester, Stoczy?ska-Fidelus Ewelina, Szybka Ma?gorzata, Banaszczyk Mateusz, Witusik-Perkowska Monika, Jesie?-Lewandowicz Emilia, Jaskólski Dariusz J, Radomiak-Za?uska Anna, Jesionek-Kupnicka Dorota, Sikorska Beata, Papierz Wielis?aw, Rieske Piotr, Liberski Pawe? |
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IDH1 mutation of gliomas with long-term survival analysis.
Oncology reports 2012 Nov 28 (5): 1639-44. Myung Jae Kyung, Cho Hwa Jin, Park Chul-Kee, Kim Seung-Ki, Phi Ji Hoon, Park Sung-H |
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Prognostic value of the TP53 Arg72Pro single-nucleotide polymorphism and susceptibility to medulloblastoma in a cohort of Brazilian patients.
Journal of neuro-oncology 2012 Oct 110 (1): 49-57. Carvalho Raimundo M, Pinto Giovanny R, Yoshioka France K N, Lima Patrícia D L, Souza Carolina R T, Guimarães Adriana C, Lamarão Letícia M, Rey Juan A, Burbano Rommel |
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1P19Q loss but not IDH1 mutations influences WHO grade II gliomas spontaneous growth.
Journal of neuro-oncology 2012 May 108 (1): 69-75. Gozé Catherine, Bezzina Charlotte, Gozé Eric, Rigau Valérie, Maudelonde Thierry, Bauchet Luc, Duffau Hugu |
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IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma.
Cancer science 2012 Feb 103 (2): 269-73. SongTao Qi, Lei Yu, Si Gui, YanQing Ding, HuiXia Han, XueLin Zhang, LanXiao Wu, Fei Y |
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IDH1 mutations in grade II astrocytomas are associated with unfavorable progression-free survival and prolonged postrecurrence survival.
Cancer 2012 Jan 118 (2): 452-60. Thon Niklas, Eigenbrod Sabina, Kreth Simone, Lutz Juergen, Tonn Joerg-Christian, Kretzschmar Hans, Peraud Aurelia, Kreth Friedrich-Wilhe |
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Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma.
Genetics and molecular research : GMR 2012 11 (4): 3618-28. Zhang J N, Yi S H, Zhang X H, Liu X Y, Mao Q, Li S Q, Xiong W H, Qiu Y M, Chen T, Ge J |
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Characterization of molecular genetic alterations in GBMs highlights a distinctive molecular profile in young adults.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2011 Dec 20 (4): 225-32. Jha Prerana, Suri Vaishali, Singh Geetika, Jha Pankaj, Purkait Suvendu, Pathak Pankaj, Sharma Vikas, Sharma Mehar Chand, Suri Ashish, Gupta Deepak, Mahapatra Ashok Kumar, Sarkar Chit |
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IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors.
Journal of neuro-oncology 2011 Nov 105 (2): 345-57. Mellai Marta, Piazzi Angela, Caldera Valentina, Monzeglio Oriana, Cassoni Paola, Valente Guido, Schiffer Davi |
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IDH1 mutations in gliomas: first series from a tertiary care centre in India with comprehensive review of literature.
Experimental and molecular pathology 2011 Aug 91 (1): 385-93. Jha Prerana, Suri Vaishali, Sharma Vikas, Singh Geetika, Sharma Mehar Chand, Pathak Pankaj, Chosdol Kunzang, Jha Pankaj, Suri Ashish, Mahapatra Ashok Kumar, Kale Shashank Sharad, Sarkar Chit |
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Association of the highly prevalent TP53 R337H mutation with pediatric choroid plexus carcinoma and osteosarcoma in southeast Brazil.
Cancer 2011 May 117 (10): 2228-35. Seidinger Ana Luiza, Mastellaro Maria José, Paschoal Fortes Fernanda, Godoy Assumpção Juliana, Aparecida Cardinalli Izilda, Aparecida Ganazza Mônica, Correa Ribeiro Raul, Brandalise Silvia Regina, Dos Santos Aguiar Simone, Yunes José Andr |
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Benefits of interferon-? and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
Cancer 2011 Apr 117 (8): 1721-30. Motomura Kazuya, Natsume Atsushi, Kishida Yugo, Higashi Hiroyuki, Kondo Yutaka, Nakasu Yoko, Abe Tatsuya, Namba Hiroki, Wakai Kenji, Wakabayashi Toshihi |
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TP53 mutations in favorable-risk Wnt/Wingless-subtype medulloblastomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Apr 29 (12): e344-6; author reply e347-8. Lindsey Janet C, Hill Rebecca M, Megahed Hisham, Lusher Meryl E, Schwalbe Ed C, Cole Michael, Hogg Twala L, Gilbertson Richard J, Ellison David W, Bailey Simon, Clifford Steven |
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First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
Neuro-oncology 2011 Feb 13 (2): 235-41. Taal Walter, Dubbink Hendrikus J, Zonnenberg Chris B L, Zonnenberg Bernard A, Postma Tjeerd J, Gijtenbeek Johanna M M, Boogerd Willem, Groenendijk Floris H, Kros Johan M, Kouwenhoven Mathilde C M, van Marion Ronald, van Heuvel Irene, van der Holt Bronno, Bromberg Jacoline E C, Sillevis Smitt Peter A E, Dinjens Winand N M, van den Bent Martin J, |
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MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation.
Journal of neuro-oncology 2011 Feb 101 (3): 405-17. Groenendijk Floris H, Taal Walter, Dubbink Hendrikus J, Haarloo Cathleen R, Kouwenhoven Mathilde C, van den Bent Martin J, Kros Johan M, Dinjens Winand N |
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Increased incidence of choroid plexus carcinoma due to the germline TP53 R337H mutation in southern Brazil.
PloS one 2011 6 (3): e18015. Custodio Gislaine, Taques Guilherme R, Figueiredo Bonald C, Gugelmin Elizabeth S, Oliveira Figueiredo Mirna M, Watanabe Flora, Pontarolo Roberto, Lalli Enzo, Torres Luiz Fernando Bleg |
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Molecular classification of low-grade diffuse gliomas.
The American journal of pathology 2010 Dec 177 (6): 2708-14. Kim Young-Ho, Nobusawa Sumihito, Mittelbronn Michel, Paulus Werner, Brokinkel Benjamin, Keyvani Kathy, Sure Ulrich, Wrede Karsten, Nakazato Yoichi, Tanaka Yuko, Vital Anne, Mariani Luigi, Stawski Robert, Watanabe Takuya, De Girolami Umberto, Kleihues Paul, Ohgaki Hiro |
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TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Dec 28 (35): 5188-96. Pfaff Elke, Remke Marc, Sturm Dominik, Benner Axel, Witt Hendrik, Milde Till, von Bueren André O, Wittmann Andrea, Schöttler Anna, Jorch Norbert, Graf Norbert, Kulozik Andreas E, Witt Olaf, Scheurlen Wolfram, von Deimling Andreas, Rutkowski Stefan, Taylor Michael D, Tabori Uri, Lichter Peter, Korshunov Andrey, Pfister Stefan |
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p53 abnormality and tumor invasion in patients with malignant astrocytoma.
Brain tumor pathology 2010 Oct 27 (2): 95-101. Momota Hiroyuki, Narita Yoshitaka, Matsushita Yuko, Miyakita Yasuji, Shibui Soichi |
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Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas.
Journal of neuro-oncology 2010 Sep 99 (2): 209-15. Antonelli Manila, Buttarelli Francesca Romana, Arcella Antonietta, Nobusawa Sumihito, Donofrio Vittoria, Oghaki Hiroko, Giangaspero Feli |
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Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation.
Familial cancer 2010 Sep 9 (3): 413-21. Robertson Lindsay B, Armstrong Georgina N, Olver Bianca D, Lloyd Amy L, Shete Sanjay, Lau Ching, Claus Elizabeth B, Barnholtz-Sloan Jill, Lai Rose, Il'yasova Dora, Schildkraut Joellen, Bernstein Jonine L, Olson Sara H, Jenkins Robert B, Yang Ping, Rynearson Amanda Lynn, Rynerason Amanda L, Wrensch Margaret, McCoy Lucie, Wienkce John K, McCarthy Bridget, Davis Faith, Vick Nicholas A, Johansen Christoffer, Bødtcher Hanne, Sadetzki Siegal, Bruchim Revital Bar-Sade, Yechezkel Galit Hirsh, Andersson Ulrika, Melin Beatrice S, Bondy Melissa L, Houlston Richard |
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Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation.
Journal of neuropathology and experimental neurology 2010 Jun 69 (6): 632-42. Temme Achim, Geiger Kathrin D, Wiedemuth Ralf, Conseur Katharina, Pietsch Torsten, Felsberg Jörg, Reifenberger Guido, Tatsuka Masaaki, Hagel Christian, Westphal Manfred, Berger Hilmar, Simon Matthias, Weller Michael, Schackert Gabrie |
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TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Apr 28 (12): 1995-2001. Tabori Uri, Shlien Adam, Baskin Berivan, Levitt Sarah, Ray Peter, Alon Noa, Hawkins Cynthia, Bouffet Eric, Pienkowska Malgorzata, Lafay-Cousin Lucie, Gozali Alexa, Zhukova Nataliya, Shane Lisa, Gonzalez Ignacio, Finlay Jonathan, Malkin Dav |
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Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Dec 27 (34): 5743-50. Weller Michael, Felsberg Jörg, Hartmann Christian, Berger Hilmar, Steinbach Joachim P, Schramm Johannes, Westphal Manfred, Schackert Gabriele, Simon Matthias, Tonn Jörg C, Heese Oliver, Krex Dietmar, Nikkhah Guido, Pietsch Torsten, Wiestler Otmar, Reifenberger Guido, von Deimling Andreas, Loeffler Mark |
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Long-term survivors of glioblastoma: clinical features and molecular analysis.
Acta neurochirurgica 2009 Nov 151 (11): 1349-58. Sonoda Yukihiko, Kumabe Toshihiro, Watanabe Mika, Nakazato Yoichi, Inoue Tomoo, Kanamori Masayuki, Tominaga Tei |
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Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Nov 15 (21): 6683-93. Felsberg Jörg, Rapp Marion, Loeser Simon, Fimmers Rolf, Stummer Walter, Goeppert Matthias, Steiger Hans-Jacob, Friedensdorf Britta, Reifenberger Guido, Sabel Michael |
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Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma.
Cancer investigation 2009 Oct 27 (8): 825-9. Shamsara Jamal, Sharif Samaneh, Afsharnezhad Sima, Lotfi Marzieh, Raziee Hamid Reza, Ghaffarzadegan Kamran, Moradi Afshin, Rahighi Saeed, Behravan Jav |
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IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas.
Neuro-oncology 2009 Aug 11 (4): 341-7. Ichimura Koichi, Pearson Danita M, Kocialkowski Sylvia, Bäcklund L Magnus, Chan Raymond, Jones David T W, Collins V Pet |
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Common polymorphisms in the MDM2 and TP53 genes and the relationship between TP53 mutations and patient outcomes in glioblastomas.
Brain pathology (Zurich, Switzerland) 2009 Apr 19 (2): 188-94. Zawlik Izabela, Kita Daisuke, Vaccarella Salvatore, Mittelbronn Michel, Franceschi Silvia, Ohgaki Hiro |
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IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas.
The American journal of pathology 2009 Apr 174 (4): 1149-53. Watanabe Takuya, Nobusawa Sumihito, Kleihues Paul, Ohgaki Hiro |
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Mutational inactivation of the nijmegen breakage syndrome gene (NBS1) in glioblastomas is associated with multiple TP53 mutations.
Journal of neuropathology and experimental neurology 2009 Feb 68 (2): 210-5. Watanabe Takuya, Nobusawa Sumihito, Lu Shengqing, Huang Jian, Mittelbronn Michel, Ohgaki Hiro |
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Worse outcome in primary glioblastoma multiforme with concurrent epidermal growth factor receptor and p53 alteration.
American journal of clinical pathology 2009 Feb 131 (2): 257-63. Ruano Yolanda, Ribalta Teresa, de Lope Angel Rodríguez, Campos-Martín Yolanda, Fiaño Concepción, Pérez-Magán Elisa, Hernández-Moneo José-Luis, Mollejo Manuela, Meléndez Bárba |
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Polymorphisms and DNA methylation of gene TP53 associated with extra-axial brain tumors.
Genetics and molecular research : GMR 2009 8 (1): 8-18. Almeida L O, Custódio A C, Pinto G R, Santos M J, Almeida J R W, Clara C A, Rey J A, Casartelli |
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Promoter methylation and polymorphisms of the MGMT gene in glioblastomas: a population-based study.
Neuroepidemiology 2009 32 (1): 21-9. Zawlik Izabela, Vaccarella Salvatore, Kita Daisuke, Mittelbronn Michel, Franceschi Silvia, Ohgaki Hiro |
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The role of a single nucleotide polymorphism of MDM2 in glioblastoma multiforme.
Journal of neurosurgery 2008 Nov 109 (5): 842-8. Khatri Rina G, Navaratne Kapila, Weil Robert |
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Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors.
Brain research 2008 Mar 1198 16-20. Idbaih Ahmed, Boisselier Blandine, Marie Yannick, Sanson Marc, El Hallani Soufiane, Crinière Emmanuelle, Fourtassi Maryam, Paris Sophie, Carpentier Catherine, Rousseau Audrey, Mokhtari Karima, Combadière Christophe, Laigle-Donadey Florence, Hoang-Xuan Khê, Delattre Jean-Yv |
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[Mutations of p53 gene in 41 cases of human brain gliomas].
Ai zheng = Aizheng = Chinese journal of cancer 2008 Jan 27 (1): 8-11. Cui Wen, Kong Xia, Cao Hui-Ling, Wang Xu, Gao Ji-Fa, Wu Ren-Liang, Wang Xue-Ch |
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TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas.
Cancer genetics and cytogenetics 2008 Jan 180 (1): 14-9. Lima-Ramos Vítor, Pacheco-Figueiredo Luís, Costa Sandra, Pardal Fernando, Silva Ana, Amorim Júlia, Lopes José Manuel, Reis Rui Manu |
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TP53 codon 72 polymorphism, p53 expression, and 1p/19q status in oligodendroglial tumors.
Cancer genetics and cytogenetics 2007 Sep 177 (2): 103-7. Idbaih Ahmed, Boisselier Blandine, Marie Yannick, El Hallani Soufiane, Sanson Marc, Crinière Emmanuelle, Rodero Mathieu, Carpentier Catherine, Paris Sophie, Laigle-Donadey Florence, Ducray François, Hoang-Xuan Khê, Delattre Jean-Yv |
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