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Last Posted: Jun 23, 2023
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Predicting personal cardiovascular disease risk based on family health history: Development of expert-based family criteria for the general population
T DIjsktra et al, EJHG, March 27, 2023

A Delphi procedure carried out in a larger group of expert physicians led to consensus on five family criteria that focus on cardiovascular events at young age (i.e., sudden death, any CVD, implantable cardioverter-defibrillator, aortic aneurysm) and/or an inherited CVD in one or more close relatives. We then applied these family criteria to a high-risk cohort from a clinical genetics department and demonstrated that they have substantial diagnostic accuracy. After further evaluation in a general population cohort, we decided to only use the family criteria for first-degree relatives.

Hypertrophic Cardiomyopathy (HCM) and Family Health History of Sudden Death
CDC, December 2022

If you have a family member, especially a parent, sibling, or child, who died suddenly before age 40, let your doctor know. You might need to be screened for HCM, a genetic condition that causes the heart muscle to become thick and can lead to sudden death. While some people with HCM are very sick, many people, especially children, teens, and young adults, have no or few symptoms and may not know they have a heart problem. Sharing your family history with your doctor can help you and other relatives find HCM early.

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