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Last Posted: May 23, 2023
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Emerging sensing and modeling technologies for wearable and cuffless blood pressure monitoring.
Lei Zhao et al. NPJ Digit Med 2023 5 (1) 93

Cardiovascular diseases (CVDs) are a leading cause of death worldwide. For early diagnosis, intervention and management of CVDs, it is highly desirable to frequently monitor blood pressure (BP), a vital sign closely related to CVDs, during people’s daily life, including sleep time. Towards this end, wearable and cuffless BP extraction methods have been extensively researched in recent years as part of the mobile healthcare initiative. This review focuses on the enabling technologies for wearable and cuffless BP monitoring platforms, covering both the emerging flexible sensor designs and BP extraction algorithms.

Interactions between the lipidome and genetic and environmental factors in autism.
Chloe X Yap et al. Nat Med (4) 936-949

Here we explored the plasma lipidome (783 lipid species) in 765 children (485 diagnosed with autism spectrum disorder (ASD)) within the Australian Autism Biobank. We identified lipids associated with ASD diagnosis (n?=?8), sleep disturbances (n?=?20) and cognitive function (n?=?8) and found that long-chain polyunsaturated fatty acids may causally contribute to sleep disturbances mediated by the FADS gene cluster.

Digital health tools to support parents with parent-infant sleep and mental well-being
HL Ball et al, NPJ Digital Medicine, December 21, 2022

Digital technology has been developed to support parents in the following four ways: (1) providing digital information on infant sleep, (2) offering targeted support for night-time care, (3) managing infant sleep and (4) monitoring infant sleep and safety. Evidence on the effectiveness of these strategies is varied and there are concerns regarding the reliability of information, use of personal data, commercial exploitation of parents, and the effects of replacing caregiver presence with digital technology.

Personalized Medicine and Obstructive Sleep Apnea
SQ Quy et al, J Per Med, December 2022

Obstructive sleep apnea (OSA) is a common disease that is often under-diagnosed and under-treated in all ages. This is due to differences in morphology, diversity in clinical phenotypes, and differences in diagnosis and treatment of OSA in children and adults, even among individuals of the same age. This narrative review seeks to describe the current concepts and relevant approaches towards personalized management of patients with OSA, according to pathophysiology, cluster analysis of clinical characteristics, adequate combined therapy, and the consideration of patients’ expectations.

Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.