Natural language processing system for rapid detection and intervention of mental health crisis chat messages.
Akshay Swaminathan et al. NPJ Digit Med 2023 11 (1) 213
From the abstract: "Patients experiencing mental health crises often seek help through messaging-based platforms, but may face long wait times due to limited message triage capacity. Here we build and deploy a machine-learning-enabled system to improve response times to crisis messages in a large, national telehealth provider network. We train a two-stage natural language processing (NLP) system with key word filtering followed by logistic regression on 721 electronic medical record chat messages, of which 32% are potential crises. "
Social and physical predictors of mental health impact in adult women who have an FMR1 premutation
C Kraan et al, Genetics in Med Open, August 26, 2023
From the abstract: "Clear understanding of mental health phenotypes and associated socioeconomic, physical health and wellbeing impacts in adult women with an FMR1 premutation (PM) is needed for counselling and primary healthcare. This is a survey of 137 participants. Depression was found in ~30% and social anxiety in ~38%. With depression status the outcome variable, strongest associations were for low education, diagnosis of migraine, diagnosis of irritable bowel syndrome (IBS) and self-reported hearing loss symptoms."
Factors associated with healthy aging in Latin American populations.
Hernando Santamaria-Garcia et al. Nat Med 2023 8
We investigated the combined impact of social determinants of health (SDH), lifestyle factors, cardiometabolic factors, mental health symptoms and demographics (age, sex) on healthy aging (cognition and functional ability) across LAC countries with different levels of socioeconomic development using cross-sectional and longitudinal machine learning models (n?=?44,394 participants). Risk factors associated with social and health disparities, including SDH (ß?>?0.3), mental health (ß?>?0.6) and cardiometabolic risks (ß?>?0.22), significantly influenced healthy aging more than age and sex.
Predictive evidence of the relevance of epigenetics to PTSD.
Leon Mutesa et al. Nat Rev Genet 2023 8
Post-traumatic stress disorder (PTSD) is a complex mental health condition that can occur after a life-threatening or otherwise traumatic event. Although its molecular causes are unclear, its development is thought to involve a range of biological, psychological and environmental factors. In 2009, Yehuda and Bierer posited that epigenetic modifications, such as DNA methylation, may occur in response to environmental influences such as trauma exposure, thus altering the functional expression of genes. These mechanisms may explain the intergenerational transmission of PTSD across affected families.