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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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86 hot topic(s) found with the query "Nutrigenomics"

Emergence of nutrigenomics and dietary components as a complementary therapy in cancer prevention.
Shambhavi Srivastava et al. Environmental science and pollution research international 2022 11 (60) 89853-89873 (Posted: Mar 02, 2023 10AM)

Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.
Pérez-Beltrán Yolanda E et al. Frontiers in nutrition 2022 4 830283 (Posted: Apr 23, 2022 9AM)

Findings included in this systematic review indicated that a certain percentage of dietary macronutrients, the consumption of specific amounts of polyunsaturated or monounsaturated fatty acids, as well as the ingestion of nutraceuticals or dietary supplements could be considered as potential strategies for the development of a wide range of nutrigenetic interventions since they have a direct impact on the blood levels of lipids.

Opportunities to integrate nutrigenomics into clinical practice and patient counseling
D Roosan et al, EJCN, April 20, 2022 (Posted: Apr 22, 2022 0PM)

We identified four main themes: inadequate training, lack of awareness, underdeveloped nutrigenomics counseling skills, and unreliable evidence-based practice information. Many clinicians did not have the necessary knowledge to perform nutrigenomic counseling and were unaware of the available scientific information source. Moreover, there are no guidelines in the scientific community to counsel patients on nutrigenomics testing.

NIH's ‘precision nutrition’ bet aims for individualized diets
J Kaiser, Science, February 5, 2021 (Posted: Feb 06, 2021 7AM)

There's no one-size-fits-all diet. If you want to avoid spiking your blood sugar with a snack, a banana may seem like a better choice than a sugary cookie. “We all know people who lose weight easily, and others who don't.” Now, the U.S. National Institutes of Health is making a major push to understand these individual differences.

Nutrigenomics: lessons learned and future perspectives.
Brennan Lorraine et al. The American journal of clinical nutrition 2021 Jan (Posted: Jan 31, 2021 0PM)

Although many of the nutrigenomic studies performed to date were labelled as proof-of-concept or pilot studies, there is ample evidence to support the use of these technologies in nutrition science. Incorporating omic technologies from the start of study designs will ensure that studies are sufficiently powered for such data.

Adolescent-Onset and Adult-Onset Vitamin-Responsive Neurogenetic Diseases: A Review.
Mandia Daniele et al. JAMA neurology 2021 Jan (Posted: Jan 12, 2021 11AM)

Vitamin-responsive neurogenetic diseases represent a group of rare conditions that are probably underdiagnosed in adults and may have a dramatic response to treatment when started early in the course of the disease. In this review, main features of the adult-onset forms are defined are provided.

Precision Nutrition-the Answer to "What to Eat to Stay Healthy".
Rodgers Griffin P et al. JAMA 2020 Aug (Posted: Aug 08, 2020 10AM)

Many studies have revealed profound differences among individuals in disease risk and biological responses to diet, making it challenging to fully answer this question. This necessitates moving beyond a one-size-fits-all dietary prescription for optimal health and disease prevention.

Do the microRNAs we eat affect gene expression?
K Campbell, Nature Outlook, June 17, 2020 (Posted: Jun 22, 2020 9AM)

Studies have suggested that genetic material can be transferred from diet. But some researchers have their doubts. The ultimate goal is to learn the language in which our food speaks to us — and to discover whether miRNAs might serve as a Rosetta Stone.

Dietary RNA is ripe for investigation
K Witwer, Nature Outlook, June 17, 2020 (Posted: Jun 22, 2020 9AM)

Opportunities abound to study whether dietary RNA is delivered to the cells of the alimentary tract and the microbes that live there. These investigations must include appropriate controls to determine whether dietary extracellular RNA is mostly a source of nutrition in the form of molecular building blocks.

NIH releases strategic plan to accelerate nutrition research over next 10 years
NIH, May 27, 2020 Brand (Posted: Jun 01, 2020 8AM)

What if each of us had individualized dietary recommendations that helped us decide what, when, why, and how to eat to optimize our health and quality of life? This precision nutrition approach — developing targeted and effective diet interventions in a diverse population — is among the ambitious goals set out by the 2020-2030 Strategic Plan

Contribution of macronutrients to obesity: implications for precision nutrition
Nat Rev Endrocrinology, March 31, 2020 (Posted: Apr 04, 2020 9AM)

the interactions of the genetic make-up and/or microbiota features of a person with specific macronutrient intakes or dietary pattern consumption help to explain individualized responses to macronutrients and food patterns, which might represent key factors for comprehensive precision nutrition recommendations.

Direct-to-Consumer Nutrigenetics Testing: An Overview.
Floris Matteo et al. Nutrients 2020 Feb 12(2) (Posted: Mar 04, 2020 9AM)

In this article, we analyze the online nutrigenetics services offered by 45 companies worldwide, to obtain an overall picture of the costs, the types of nutritional traits considered and the level of scientific precision of the services proposed.

Information Provided to Consumers about Direct-to-Consumer Nutrigenetic Testing.
De Suchetana et al. Public health genomics 2019 Nov 1-12 (Posted: Dec 04, 2019 9AM)

The complex structure of the websites made it difficult to find all key information, with many important aspects buried in legal documents, which were challenging to comprehend even for a professional. The structure of the websites and the amount and quality of the content therein do not support a well-informed decision.

Using genetics to disentangle the complex relationship between food choices and health status
N Pirastu et al, BIORXIV, November 8, 2019 (Posted: Nov 09, 2019 8AM)

After identifying 302 (289 novel) individual genetic determinants of dietary intake in 445,779 individuals in the UK Biobank study, we develop a statistical genetics framework that enables us, for the first time, to directly assess the impact of food choices on health outcomes.

Individualized diets help patients with inherited metabolic disorders
S Rosen Mayo Clinic, Individualized Medicine Blog, October 4,2019 (Posted: Oct 07, 2019 9AM)

Patients with inborn errors of metabolism have genetic variations that interfere with their bodies’ metabolism, affecting the ability to process different nutrients found in food. That’s why finding the right nutritional balance is critical to managing their overall health and avoiding serious, sometimes life-threatening symptoms.

Personalized Nutrition: The Latest on DNA-Based Diets
Scientific American, September 27, 2019 (Posted: Oct 01, 2019 8AM)

Since the sequencing of the human genome, there's been a lot of interest in nutrigenomics. It’s long been clear that we don’t all respond the same way to the same dietary interventions. Some people do really well on a higher fat diet. Others develop high triglycerides or cholesterol on the same diet.

Are Personalized Diets Ready for Prime Time?
D Koenig, WebMD, September 19, 2019 (Posted: Sep 22, 2019 0PM)

“There isn't anything proven yet with DNA. So let's be clear about that,” he says. “The only real breakthrough in recent years has been capturing all of a person's data, including their gut microbiome data.”

‘Precision nutrition’ may be on the horizon, but large-scale, definitive trials lacking
LL Peterson, Healio, Sepetmber 10, 2019 (Posted: Sep 12, 2019 7AM)

Nutrigenetics and NutrigenomicsApproaches for Nutrition Research
NIH funding Announcement, September 2019 Brand (Posted: Sep 12, 2019 7AM)

A gene-diet interaction-based score predicts response to dietary fat in the Women's Health Initiative
K Westerman et al, MedXRIV, August 2019 (Posted: Aug 23, 2019 8AM)

The study sought to leverage the Women's Health Initiative cohort to generate and test genetic scores for the response of six cardiometabolic risk factors (body mass index, systolic blood pressure, LDL-cholesterol, HDL-cholesterol, triglycerides, and fasting glucose) to dietary fat.

The Food Programme, Is There A Perfect Diet Just For You? The Future of Personalised Nutrition
BBC Radio 4 (Posted: Jul 15, 2019 1PM)

Diet for One? Scientists Stalk the Dream of Personalized Nutrition- No single food regimen works for everyone. A new study is the most comprehensive effort yet to understand why.
C Graber et al, NY Times, June 10, 2019 (Posted: Jun 10, 2019 10AM)

Nutrigenetic Testing for Personalized Nutrition: An Evaluation of Public Perceptions, Attitudes, and Concerns in a Population of French Canadians.
Vallée Marcotte Bastien et al. Lifestyle genomics 2019 May 1-8 (Posted: May 29, 2019 8AM)

"Omics" Education in Dietetic Curricula: A Comparison between Two Institutions in the USA and Mexico.
VanBuren Christine et al. Lifestyle genomics 2019 May 1-11 (Posted: May 15, 2019 8AM)

Update on Genetic Testing
J Weisenberger, Today's Dietitian, May 2019 (Posted: May 08, 2019 8AM)

Why You Don't Actually Need to Test for MTHFR Gene Variants
TC Smith, Self, March 2019 (Posted: Mar 24, 2019 9AM)

Primers on nutrigenetics and nutri(epi)genomics: Origins and development of precision nutrition.
Bordoni Laura et al. Biochimie 2019 Mar 160156-171 (Posted: Mar 20, 2019 9AM)

Study protocol of a pragmatic randomized controlled trial incorporated into the Group Lifestyle Balance™ program: the nutrigenomics, overweight/obesity and weight management trial (the NOW trial).
Horne Justine et al. BMC public health 2019 Mar 19(1) 310 (Posted: Mar 20, 2019 9AM)

Apps step up to the plate with diet and DNA-tailored advice
S Debrebant, Financial Times, March 11, 2019 (Posted: Mar 14, 2019 8AM)

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.
Guest Nanci S et al. Frontiers in nutrition 2019 8 (Posted: Mar 11, 2019 9AM)

From nutrigenomics to personalizing diets: are we ready for precision medicine?
Loos Ruth J F et al. The American journal of clinical nutrition 2019 Jan (1) 1-2 (Posted: Feb 06, 2019 8AM)

Current and Future Landscape of Nutritional Epidemiologic Research
FB Hu et al. JAMA, October 31, 2018 (Posted: Oct 31, 2018 11AM)

Personalised nutrition and health.
Ordovas Jose M et al. BMJ (Clinical research ed.) 2018 06 bmj.k2173 (Posted: Oct 31, 2018 8AM)

Your DNA, Your Diet: How Nutrition Is Being Personalized At-home tests are helping people learn more about their bodies, but the science is still evolving
C Ostroff, WSJ, August 30, 2018 (Posted: Aug 31, 2018 11AM)

Nutrigenomics and the Future of Nutrition: Proceedings of a Workshop.
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Food Forum, 2018 (Posted: Aug 24, 2018 9AM)

Associations between Single Nucleotide Polymorphisms and Total Energy, Carbohydrate, and Fat Intakes: A Systematic Review.
Drabsch Theresa et al. Advances in nutrition (Bethesda, Md.) 2018 Jul (4) 425-453 (Posted: Jul 23, 2018 11AM)

Genome-Tailored Diets May Be Premature
GEN News Highlights, July 23, 2018 (Posted: Jul 23, 2018 11AM)

Nutritional Genomics and Direct-to-Consumer Genetic Testing: An Overview.
Guasch-Ferré Marta et al. Advances in nutrition (Bethesda, Md.) 2018 Mar 9(2) 128-135 (Posted: Apr 18, 2018 10AM)

Genes might not predict success of low-fat or low-carb diet
L Rappaport, Reuters Health, Feb 20, 2018 (Posted: Feb 20, 2018 1PM)

Matching DNA to a diet doesn’t work: ‘We didn’t even come close,’ researcher says
S Begley, Stat News, Feb 20, 2018 (Posted: Feb 20, 2018 0PM)

Personalized Diets: Can Your Genes Really Tell You What To Eat?
A Aubrey, NPR, Jan 22, 2018 (Posted: Jan 22, 2018 0PM)

Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice
KA Grimaldi et al, Genes and Nutrition, Dec 2017 (Posted: Dec 29, 2017 11AM)

Opportunities for training for nutritional professionals in nutritional genomics: What is out there?
Collins Jorja et al. Nutrition & dietetics: the journal of the Dietitians Association of Australia 2017 Dec (Posted: Dec 20, 2017 0PM)

Scientific Evidence for Personalized Nutrition: Ethical Implications of Methological Limitations
C Jannsens, Slide Presentation, Dec 2017 (Posted: Dec 06, 2017 11AM)

A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions.
Janssens A Cecile J W et al. American journal of human genetics 2008 Mar (3) 593-9 (Posted: Dec 04, 2017 11AM)

The future of nutrition: Nutrigenomics and nutrigenetics in obesity and cardiovascular diseases.
Peña-Romero Alicia Cristina et al. Critical reviews in food science and nutrition 2017 Jul 1-12 (Posted: Nov 07, 2017 9AM)

Nutrigenetics and Nutrigenomics Approaches for Nutrition Research
NIH Funding Opportunity, Nov 2017 (Posted: Nov 07, 2017 9AM)

An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise.
Ahn Woo-Kyoung et al. Appetite 2017 Aug 12023-31 (Posted: Aug 30, 2017 9AM)

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity.
Ramos-Lopez Omar et al. Journal of nutrigenetics and nutrigenomics 2017 Jul 10(1-2) 43-62 (Posted: Jul 12, 2017 11AM)

The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial.
Fallaize Rosalind et al. The American journal of clinical nutrition 2016 Sep 104(3) 827-36 (Posted: Jun 07, 2017 9AM)

Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate
A Ortega et al, Int J Mol SCi, June 2017 (Posted: Jun 05, 2017 5PM)

Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease: a guide for upcoming studies and implementations.
Corella Dolores et al. Expert review of molecular diagnostics 2017 May (5) 495-513 (Posted: May 24, 2017 11AM)

Uninformed consent in nutrigenomic research
AC Janssens et al, Eur J Human Genetics, May 10, 2017 (Posted: May 10, 2017 2PM)

Transcriptomics and the Mediterranean Diet: A Systematic Review.
Herrera-Marcos Luis V et al. Nutrients 2017 May (5) (Posted: May 10, 2017 6AM)

Crave Sugar? Maybe It's in Your Genes
Scientific American, May 2, 2017 (Posted: May 03, 2017 10AM)

These DNA Diet Apps Want to Rule Your Health
A Ossola, Back Channel, May 1, 2017 (Posted: May 02, 2017 10AM)

Could genetics influence what we like to eat?
Science magazine, April 23, 2017 (Posted: Apr 23, 2017 8AM)

Translation of Nutritional Genomics into Nutrition Practice: The Next Step.
Murgia Chiara et al. Nutrients 2017 Apr 9(4) (Posted: Apr 12, 2017 8AM)

Precision nutrition: Hype or hope?
Harvard School of Public Health, February 2017 (Posted: Mar 20, 2017 4PM)

Should your DNA determine what’s for dinner?
University of Toronto, Blog post, March 2017 (Posted: Mar 07, 2017 3PM)

Nutrigenomics of extra-virgin olive oil: A review.
Piroddi Marta et al. BioFactors (Oxford, England) 2017 Jan (1) 17-41 (Posted: Mar 04, 2017 7AM)

Bioactive Nutrients and Nutrigenomics in Age-Related Diseases.
Rescigno Tania et al. Molecules (Basel, Switzerland) 2017 Jan (1) (Posted: Mar 04, 2017 7AM)

Will Diet and Exercise Save Us All?
J Monteiro, Cell, December 2016 (Posted: Dec 02, 2016 8AM)

The DNA-based diet
R. Collier, November 9, 2016 (Posted: Nov 09, 2016 4PM)

"Personalized nutrition” isn’t going to solve our diet problems
J Belluz, Vox, November 2, 2016 (Posted: Nov 02, 2016 0PM)

Nutrigenomics at the Interface of Aging, Lifespan, and Cancer Prevention.
Riscuta Gabriela et al. The Journal of nutrition 2016 Oct (10) 1931-1939 (Posted: Oct 10, 2016 7PM)

Your genes, diet and health: what you need to know
Genomics education UK, September 2016 (Posted: Oct 10, 2016 3PM)

Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition.
Ferguson Lynnette R et al. Journal of nutrigenetics and nutrigenomics 2016 May 9(1) 12-27 (Posted: May 18, 2016 10AM)

Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment A Scientific Statement From the American Heart Association
JF Ferguson et al, AHA Scientific Statement, Circulation, Cardiovascular Genetics, April 2016 (Posted: Apr 24, 2016 8AM)

Nutrigenomics 2.0: The Need for Ongoing and Independent Evaluation and Synthesis of Commercial Nutrigenomics Tests' Scientific Knowledge Base for Responsible Innovation.
Pavlidis Cristiana et al. Omics : a journal of integrative biology 2016 Feb (2) 65-8 (Posted: Mar 01, 2016 0PM)

A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.
Luceri Cristina et al. European journal of nutrition 2015 Dec (Posted: Mar 01, 2016 0PM)

Precision Nutrition 4.0: A Big Data and Ethics Foresight Analysis-Convergence of Agrigenomics, Nutrigenomics, Nutriproteomics, and Nutrimetabolomics.
Özdemir Vural et al. Omics : a journal of integrative biology 2016 Feb (2) 69-75 (Posted: Mar 01, 2016 0PM)

Nutrigenomics: A controversy
C Pavlidis et al. Appl & Trans Genomics, March 2015 (Posted: May 16, 2015 7AM)

The exposome concept in a human nutrigenomics study: evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signatures.
van Breda Simone G J et al. Mutagenesis 2015 Feb 22. (Posted: May 16, 2015 7AM)

Obesity: interactions of genome and nutrients intake.
Doo Miae et al. Prev Nutr Food Sci 2015 Mar (1) 1-7 (Posted: Apr 18, 2015 8AM)

The 9th Congress of the International Society of Nutrigenetics and Nutrigenomics
Chapel Hill, NC, May 17-19, 2015 (Posted: Apr 18, 2015 8AM)

Nutrigenomics: Can diets be tailored to an individual?s genetic make-up?
David Warmflash | April 15, 2015 | Genetic LiteracyProject (Posted: Apr 18, 2015 8AM)

Dietary Patterns, Genes, and Health: Challenges and Obstacles to be Overcome.
Frazier-Wood Alexis C et al. Curr Nutr Rep 2015;4:82-87 (Posted: Feb 24, 2015 9AM)

Can metabolically healthy obesity be explained by diet, genetics, and inflammation?
Navarro Estanislau et al. Mol Nutr Food Res 2015 Jan (1) 75-93 (Posted: Feb 24, 2015 5AM)

Epigenetic linkage of aging, cancer and nutrition.
Daniel Michael et al. J. Exp. Biol. 2015 Jan 1. (Pt 1) 59-70 (Posted: Feb 24, 2015 5AM)

Nutrigenomics: definitions and advances of this new science.
Sales N M R et al. J Nutr Metab 2014 202759 (Posted: Feb 24, 2015 5AM)

Nutrigenetic associations with cardiovascular disease.
Nuno Natasha Bushnell et al. Rev Cardiovasc Med 2014 (3) 217-25 (Posted: Feb 24, 2015 5AM)

Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis.
Berná Genoveva et al. Nutrients 2014 Nov (11) 5338-69 (Posted: Feb 24, 2015 5AM)

Nutrigenomics of essential oils and their potential domestic use for improving health.
Cayuela Sánchez José Antonio et al. Nat Prod Commun 2014 Nov (11) 1641-8 (Posted: Feb 24, 2015 5AM)

Nutrition Panel Calls for Less Sugar and Eases Cholesterol and Fat Restrictions
A. O'Connor, New York Times, February 19, 2015 (Posted: Feb 24, 2015 5AM)

Behind New Dietary Guidelines, Better Science
New York Times, February 23, 2015 (Posted: Feb 24, 2015 5AM)


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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