CDC-Authored Genomics and Precision Health Publications Database
Last data update: Nov 04, 2024. (Total: 6390 publications)
Query Trace: Hawkins PA[original query] |
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Impact of pneumococcal conjugate vaccines on invasive pneumococcal disease-causing lineages among South African children
Lekhuleni C , Ndlangisa K , Gladstone RA , Chochua S , Metcalf BJ , Li Y , Kleynhans J , de Gouveia L , Hazelhurst S , Ferreira ADS , Skosana H , Walaza S , Quan V , Meiring S , Hawkins PA , McGee L , Bentley SD , Cohen C , Lo SW , von Gottberg A , du Plessis M . Nat Commun 2024 15 (1) 8401 |
Molecular characterization of Streptococcus pneumoniae causing disease among children in Nigeria during the introduction of PCV10 (GSK)
Lo SW , Hawkins PA , Jibir B , Hassan-Hanga F , Gambo M , Olaosebikan R , Olanipekun G , Munir H , Kocmich N , Rezac-Elgohary A , Gambo S , Bagenda D , Fey P , Breiman RF , McGee L , Bentley SD , Obaro SK . Microb Genom 2023 9 (9) |
Novel pneumococcal capsule type 33E results from the inactivation of glycosyltransferase WciE in vaccine type 33F
Ganaie FA , Saad JS , Lo SW , McGee L , van Tonder AJ , Hawkins PA , Calix JJ , Bentley SD , Nahm MH . J Biol Chem 2023 299 (9) 105085 |
Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011-2018 determined through whole-genome sequencing.
Egorova E , Kumar N , Gladstone RA , Urban Y , Voropaeva E , Chaplin AV , Rumiantseva E , Svistunova TS , Hawkins PA , Klugman KP , Breiman RF , McGee L , Bentley SD , Lo SW . Microb Genom 2022 8 (9) |
Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study.
Lo SW , Mellor K , Cohen R , Alonso AR , Belman S , Kumar N , Hawkins PA , Gladstone RA , von Gottberg A , Veeraraghavan B , Ravikumar KL , Kandasamy R , Pollard SAJ , Saha SK , Bigogo G , Antonio M , Kwambana-Adams B , Mirza S , Shakoor S , Nisar I , Cornick JE , Lehmann D , Ford RL , Sigauque B , Turner P , Moïsi J , Obaro SK , Dagan R , Diawara I , SkoczyÅ„ska A , Wang H , Carter PE , Klugman KP , Rodgers G , Breiman RF , McGee L , Bentley SD , Almagro CM , Varon E . Lancet Microbe 2022 3 (10) e735-e743 |
Genetic background of Cambodian pneumococcal carriage isolates following pneumococcal conjugate vaccine 13.
Belman S , Soeng S , Soputhy C , Gladstone R , Hawkins PA , Breiman RF , McGee L , Bentley SD , Lo SW , Turner P . Microb Genom 2022 8 (6) |
A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV.
Ndlangisa KM , du Plessis M , Lo S , de Gouveia L , Chaguza C , Antonio M , Kwambana-Adams B , Cornick J , Everett DB , Dagan R , Hawkins PA , Beall B , Corso A , Grassi Almeida SC , Ochoa TJ , Obaro S , Shakoor S , Donkor ES , Gladstone RA , Ho PL , Paragi M , Doiphode S , Srifuengfung S , Ford R , Moïsi J , Saha SK , Bigogo G , Sigauque B , Eser Ö K , Elmdaghri N , Titov L , Turner P , Kumar KLR , Kandasamy R , Egorova E , Ip M , Breiman RF , Klugman KP , McGee L , Bentley SD , von Gottberg A , The Global Pneumococcal Sequencing Consortium . Microb Genom 2022 8 (4) |
Genomic surveillance of invasive Streptococcus pneumoniae isolates in the period pre-PCV10 and post-PCV10 introduction in Brazil.
Almeida SCG , Lo SW , Hawkins PA , Gladstone RA , Cassiolato AP , Klugman KP , Breiman RF , Bentley SD , McGee L , Brandileone MC . Microb Genom 2021 7 (10) |
Population genetic structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae causing invasive disease in children in Argentina.
Gagetti P , Lo SW , Hawkins PA , Gladstone RA , Regueira M , Faccone D , Sireva-Argentina Group , Klugman KP , Breiman RF , McGee L , Bentley SD , Corso A . Microb Genom 2021 7 (9) |
Streptococcus pneumoniae genomic datasets from an Indian population describing pre-vaccine evolutionary epidemiology using a whole genome sequencing approach.
Nagaraj G , Govindan V , Ganaie F , Venkatesha VT , Hawkins PA , Gladstone RA , McGee L , Breiman RF , Bentley SD , Klugman KP , Lo SW , Ravikumar KL . Microb Genom 2021 7 (9) |
A Nationwide Outbreak of Invasive Pneumococcal Disease in Israel Caused by Streptococcus Pneumoniae Serotype 2.
Dagan R , Ben-Shimol S , Benisty R , Regev-Yochay G , Lo SW , Bentley SD , Hawkins PA , McGee L , Ron M , Givon-Lavi N , Valinsky L , Rokney A . Clin Infect Dis 2020 73 (11) e3768-e3777 |
Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates.
Gladstone RA , Lo SW , Goater R , Yeats C , Taylor B , Hadfield J , Lees JA , Croucher NJ , van Tonder AJ , Bentley LJ , Quah FX , Blaschke AJ , Pershing NL , Byington CL , Balaji V , Hryniewicz W , Sigauque B , Ravikumar KL , Almeida SCG , Ochoa TJ , Ho PL , du Plessis M , Ndlangisa KM , Cornick JE , Kwambana-Adams B , Benisty R , Nzenze SA , Madhi SA , Hawkins PA , Pollard AJ , Everett DB , Antonio M , Dagan R , Klugman KP , von Gottberg A , Metcalf BJ , Li Y , Beall BW , McGee L , Breiman RF , Aanensen DM , Bentley SD . Microb Genom 2020 6 (5) |
A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.
Lo SW , Gladstone RA , van Tonder AJ , Du Plessis M , Cornick JE , Hawkins PA , Madhi SA , Nzenze SA , Kandasamy R , Ravikumar KL , Elmdaghri N , Kwambana-Adams B , Almeida SCG , Skoczynska A , Egorova E , Titov L , Saha SK , Paragi M , Everett DB , Antonio M , Klugman KP , Li Y , Metcalf BJ , Beall B , McGee L , Breiman RF , Bentley SD , von Gottberg A . J Antimicrob Chemother 2019 75 (3) 512-520 |
Putative novel cps loci in a large global collection of pneumococci.
van Tonder AJ , Gladstone RA , Lo SW , Nahm MH , du Plessis M , Cornick J , Kwambana-Adams B , Madhi SA , Hawkins PA , Benisty R , Dagan R , Everett D , Antonio M , Klugman KP , von Gottberg A , Breiman RF , McGee L , Bentley SD . Microb Genom 2019 5 (7) |
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Lo SW , Gladstone RA , van Tonder AJ , Lees JA , du Plessis M , Benisty R , Givon-Lavi N , Hawkins PA , Cornick JE , Kwambana-Adams B , Law PY , Ho PL , Antonio M , Everett DB , Dagan R , von Gottberg A , Klugman KP , McGee L , Breiman RF , Bentley SD . Lancet Infect Dis 2019 19 (7) 759-769 |
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
Gladstone RA , Lo SW , Lees JA , Croucher NJ , van Tonder AJ , Corander J , Page AJ , Marttinen P , Bentley LJ , Ochoa TJ , Ho PL , du Plessis M , Cornick JE , Kwambana-Adams B , Benisty R , Nzenze SA , Madhi SA , Hawkins PA , Everett DB , Antonio M , Dagan R , Klugman KP , von Gottberg A , McGee L , Breiman RF , Bentley SD . EBioMedicine 2019 43 338-346 |
Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis.
Li Y , Metcalf BJ , Chochua S , Li Z , Walker H , Tran T , Hawkins PA , Gierke R , Pilishvili T , McGee L , Beall BW . Nat Commun 2019 10 (1) 178 |
Global distribution of invasive serotype 35D Streptococcus pneumoniae post-PCV13 introduction.
Lo SW , Gladstone RA , van Tonder AJ , Hawkins PA , Kwambana-Adams B , Cornick JE , Madhi SA , Nzenze SA , du Plessis M , Kandasamy R , Carter PE , Koseoglu Eser O , Ho PL , Elmdaghri N , Shakoor S , Clarke SC , Antonio M , Everett DB , von Gottberg A , Klugman KP , McGee L , Breiman RF , Bentley SD . J Clin Microbiol 2018 56 (7) |
Antimicrobial resistance determinants and susceptibility profiles of pneumococcal isolates recovered in Trinidad and Tobago.
Hawkins PA , Akpaka PE , Nurse-Lucas M , Gladstone R , Bentley SD , Breiman RF , McGee L , Swanston WH . J Glob Antimicrob Resist 2017 11 148-151 |
Validation of ß-lactam minimum inhibitory concentration predictions for pneumococcal isolates with newly encountered penicillin binding protein (PBP) sequences.
Li Y , Metcalf BJ , Chochua S , Li Z , Gertz RE Jr , Walker H , Hawkins PA , Tran T , McGee L , Beall BW . BMC Genomics 2017 18 (1) 621 |
Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA.
Hawkins PA , Law CS , Metcalf BJ , Chochua S , Jackson DM , Westblade LF , Jerris R , Beall BW , McGee L . J Antimicrob Chemother 2017 72 (7) 1886-1892 |
Short-read whole genome sequencing for determination of antimicrobial resistance mechanisms and capsular serotypes of current invasive Streptococcus agalactiae recovered in the United States.
Metcalf BJ , Chochua S , Gertz RE Jr , Hawkins PA , Ricaldi J , Li Z , Walker H , Tran T , Rivers J , Mathis S , Jackson D , Glennen A , Lynfield R , McGee L , Beall B . Clin Microbiol Infect 2017 23 (8) 574 e7-574 e14 |
Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States.
Metcalf BJ , Chochua S , Gertz RE Jr , Li Z , Walker H , Tran T , Hawkins PA , Glennen A , Lynfield R , Li Y , McGee L , Beall B . Clin Microbiol Infect 2016 22 (12) 1002 e1-1002 e8 |
Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting ß-Lactam Resistance Levels in Streptococcus pneumoniae.
Li Y , Metcalf BJ , Chochua S , Li Z , Gertz RE Jr , Walker H , Hawkins PA , Tran T , Whitney CG , McGee L , Beall BW . mBio 2016 7 (3) |
Serotypes and genotypes of Streptococcus pneumoniae isolates from Trinidad and Tobago.
Nurse-Lucas M , McGee L , Hawkins PA , Swanston WH , Akpaka PE . Int J Infect Dis 2016 46 100-106 |
Strain features and distributions in pneumococci from children with invasive disease before and after 13 valent conjugate vaccine implementation in the United States.
Metcalf BJ , Gertz RE Jr , Gladstone RA , Walker H , Sherwood LK , Jackson D , Li Z , Law C , Hawkins PA , Chochua S , Sheth M , Rayamajhi N , Bentley SD , Kim L , Whitney CG , McGee L , Beall B . Clin Microbiol Infect 2015 22 (1) 60 e9-60 e29 |
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