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Last Posted: Oct 30, 2023

• Digital lifestyle treatment improves long-term metabolic control in type 2 diabetes with different effects in pathophysiological and genetic subgroups.
  Vishal A Salunkhe et al. NPJ Digit Med 2023 10 (1) 199
• Genotype-stratified treatment for monogenic insulin resistance: a systematic review
  RK Semple et al, Comm Medicine, October 5, 2023
• Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes.
  Soo Heon Kwak et al. Res Sq 2023
• Association of triglyceride-glucose index with atherosclerotic cardiovascular disease and mortality among familial hypercholesterolemia patients.
  Jun Wen et al. Diabetology & metabolic syndrome 2023 15(1) 39
• Clinical Spectrum of LMNA-Associated Type 2 Familial Partial Lipodystrophy: A Systematic Review.
  Antia Fernandez-Pombo et al. Cells 2023 12(5)
• Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
  K Alaine Broadaway et al. American journal of human genetics 2023 1
• Prediction of type 2 diabetes using genome-wide polygenic risk score and metabolic profiles: A machine learning analysis of population-based 10-year prospective cohort study.
  Hahn Seok-Ju et al. EBioMedicine 2022 86104383
• Medication Adherence and Cardiometabolic Control Indicators Among American Indian Adults Receiving Tribal Health Services: Protocol for a Longitudinal Electronic Health Records Study.
  Scarton Lisa et al. JMIR research protocols 2022 11(10) e39193
• Detecting High-Risk Factors and Early Diagnosis of Diabetes Using Machine Learning Methods.
  Ullah Zahid et al. Computational intelligence and neuroscience 2022 20222557795
• Development and Validation of an Insulin Resistance Model for a Population with Chronic Kidney Disease Using a Machine Learning Approach.
  Lee Chia-Lin et al. Nutrients 2022 14(14)
• Integrated multiomic characterization of congenital heart disease.
  Hill Matthew C et al. Nature 2022
• Heterogeneity in statin responses explained by variation in the human gut microbiome
  T Wilmansky et al, Med, May 11, 2022
• Association between circulating microRNAs and the metabolic syndrome in adult populations: A systematic review.
  Solís-Toro Daniel et al. Diabetes & metabolic syndrome 2021 16(1) 102376
• Genetics and Clinical Characteristics of PPARγ Variant-Induced Diabetes in a Chinese Han Population.
  Gong Siqian et al. Frontiers in endocrinology 2021 12677130
• Potential evidence for epigenetic biomarkers of metabolic syndrome in human whole blood in Latinos.
  Urashima Keane et al. PloS one 2021 16(10) e0259449
• Genetic and clinical heterogeneity of permanent neonatal diabetes mellitus: a single tertiary centre experience.
  Laimon Wafaa et al. Acta diabetologica 2021
• Random forest approach for determining risk prediction and predictive factors of type 2 diabetes: large-scale health check-up data in Japan.
  Ooka Tadao et al. BMJ nutrition, prevention & health 2021 4(1) 140-148
• Deciphering CT texture features of human visceral fat to evaluate metabolic disorders and surgery-induced weight loss effects.
  Shi Juan et al. EBioMedicine 2021 69103471
• HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women.
  Clément Andrée-Anne et al. Epigenomics 2021
• The comparison of the effectiveness and safety of drospirone ethinyl estradiol and ethinyl estradiol cyproterone in the treatment of polycystic ovarian syndrome: A protocol for systematic review and meta-analysis.
  Liu Zhimin et al. Medicine 2020 Dec 99(51) e23811
• Significance of Homocysteine Levels in the Management of Polycystic Ovarian Syndrome: A Literature Review.
  Kondapaneni Varshitha et al. Cureus 2020 Oct 12(10) e11110
• Reducing HbA1c in Type 2 Diabetes Using Digital Twin Technology-Enabled Precision Nutrition: A Retrospective Analysis.
  Shamanna Paramesh et al. Diabetes therapy : research, treatment and education of diabetes and related disorders 2020 Sep
• IGF2BP2 Polymorphisms Are Associated with Clinical Characteristics and Development of Oral Cancer.
  Chou Chia-Hsuan et al. International journal of molecular sciences 2020 Aug 21(16)
• Dietary Recommendations for Familial Hypercholesterolaemia: an Evidence-Free Zone.
  Diamond David M et al. BMJ evidence-based medicine 2020 Jul
• Evaluation of the suitability of 19 pharmacogenomics biomarkers for individualized metformin therapy for type 2 diabetes patients.
  Xhakaza Lettilia et al. Drug metabolism and personalized therapy 2020 Jun
• Understanding the Pathogenesis, Therapeutic Targets/Drug Action and Pharmacogenetics of Type 2 Diabetes: Is there a Future for Personalised Medicine?
  Engwa Godwill Azeh et al. Endocrine, metabolic & immune disorders drug targets 2020 Apr
• New clinical screening strategy to distinguish HNF1A variant-induced diabetes from young early-onset type 2 diabetes in a Chinese population.
  Ma Yumin et al. BMJ open diabetes research & care 2020 Mar 8(1)
• Lifestyle intervention modifies the effect of the MC4R genotype on changes in insulin resistance among women with prior gestational diabetes: Tianjin Gestational Diabetes Mellitus Prevention Program.
  Chen Yuhang et al. The American journal of clinical nutrition 2019 110(3) 750-758
• An unsupervised learning approach to identify novel signatures of health and disease from multimodal data.
  Shomorony Ilan et al. Genome medicine 2020 Jan 12(1) 7
• Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study
  MC Georgakis et al, MedRXIV, December 30, 2019
• Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach.
  Franck Maximilien et al. Lifestyle genomics 2019 Nov 1-11
• Progress in pediatrics in 2015: choices in allergy, endocrinology, gastroenterology, genetics, haematology, infectious diseases, neonatology, nephrology, neurology, nutrition, oncology and pulmonology.
  Caffarelli Carlo et al. Italian journal of pediatrics 2016 Aug 42(1) 75
• High Genetic Risk Scores of ASIC2, MACROD2, CHRM3, and C2orf83 Genetic Variants Associated with Polycystic Ovary Syndrome Impair Insulin Sensitivity and Interact with Energy Intake in Korean Women.
  Kim Sung-Hoon et al. Gynecologic and obstetric investigation 2019 84(3) 225-236
• Genomics and PCOS
  Genomics Education UK, August 5, 2019
• TyG-er: An ensemble Regression Forest approach for identification of clinical factors related to insulin resistance condition using Electronic Health Records.
  Bernardini Michele et al. Computers in biology and medicine 2019 Jul 112103358
• Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.
  Shabani Azade et al. Journal of affective disorders 2019 25051-56
• Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
  Depommier Clara, et al. Nature medicine 2019 7 0. (7) 1096-1103
• Identification of type 2 diabetes loci in 433,540 East Asian individuals
  CN Spracklen et al, BioRXIV, June 28, 2019
• The Human Microbiome Project expands the toolbox for studying host and microbiome interactions
  NIH, May 29, 2019
• A longitudinal big data approach for precision health.
  Schüssler-Fiorenza Rose Sophia Miryam et al. Nature medicine 2019 May 25(5) 792-804
• Circulating obesity-driven biomarkers are associated with risk of clear cell renal cell carcinoma: a two-stage, case-control study.
  Wang Qinchuan et al. Carcinogenesis 2019 Apr
• Current Progress in Pharmacogenetics of Second-Line Antidiabetic Medications: Towards Precision Medicine for Type 2 Diabetes.
  Heo Chan Uk et al. Journal of clinical medicine 2019 Mar 8(3)
• No clinical utility of common polymorphisms in IGF1, IRS1, GCKR, PPARG, GCK1 and KCTD1 genes previously associated with insulin resistance in overweight children from Romania and Moldova.
  Chirita-Emandi Adela et al. Journal of pediatric endocrinology & metabolism : JPEM 2019 Jan 32(1) 33-39
• Body mass index and C-peptide are important for the promptly differential diagnosis of maturity-onset diabetes from familial type 2 diabetes in outpatient clinic.
  Wu Hui-Xuan et al. Endocrine journal 2019 Feb
• Insulin resistance in children with familial hyperlipidemia.
  Terlemez Semiha et al. Journal of pediatric endocrinology & metabolism : JPEM 2018 Nov
• Pharmacogenetics of Risperidone-Induced Insulin Resistance in Children and Adolescents with Autism Spectrum Disorder.
  Sukasem Chonlaphat et al. Basic & clinical pharmacology & toxicology 2018 Jul 123(1) 42-50
• Monogenic forms of lipodystrophic syndromes: diagnosis, detection, and practical management considerations from clinical cases.
  Vatier Camille et al. Current medical research and opinion 2018 Oct 1-22
• Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
  Udler Miriam S et al. PLoS medicine 2018 Sep 15(9) e1002654
• CLINGEN Actionability Report for Hyperandrogenism, nonclassic type, due to 21-hydroxylase deficiency - CYP21A2
  ClinGen Actionability Working Group
• Genetic risk scores in the prediction of plasma glucose, impaired insulin secretion, insulin resistance and incident type 2 diabetes in the METSIM study.
  Stancáková Alena et al. Diabetologia 2017 Sep 60(9) 1722-1730
• Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association.
  Volgman Annabelle Santos et al. Circulation 2018 May
• Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtype
  MS Udler et al, BioRXIV, May 2018
• Genetic syndromes of severe insulin resistance.
  Melvin A et al. Current opinion in genetics & development 2018 Feb 5060-67
• Lifestyle precision medicine: the next generation in type 2 diabetes prevention?
  Mutie Pascal M et al. BMC medicine 2017 15(1) 171
• Integrative Personal Omics Profiles during Periods of Weight Gain and Loss.
  Piening Brian D et al. Cell systems 2018 Jan
• Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight.
  Huang Lam Opal et al. Physiological genomics 2017 Dec
• Precision Medicine in Obesity and Type 2 Diabetes: The Relevance of Early-Life Exposures.
  Estampador Angela C et al. Clinical chemistry 2018 Jan 64(1) 130-141
• Genetic variation of habitual coffee consumption and glycemic changes in response to weight-loss diet intervention: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial.
  Han Liyuan et al. The American journal of clinical nutrition 2017 Nov 106(5) 1321-1326
• Leukocyte Telomere Length in Relation to 17 Biomarkers of Cardiovascular Disease Risk: A Cross-Sectional Study of US Adults.
  Rehkopf David H, et al. PLoS medicine 2016 11 0. (11) e1002188
• Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.
  Ussar Siegfried et al. Molecular metabolism 2016 Sep 5(9) 795-803

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