Irinotecan
What's New
Last Posted: Feb 08, 2023
- Towards UGT1A1 guided irinotecan dosing
JK Hicks, EJHG, February 7, 2023 - Treatment of childhood sarcoma with irinotecan: bilirubin level as a predictor of gastrointestinal toxicity.
Ruggiero A, et al. Journal of chemotherapy (Florence, Italy) 2010 0 (6) 693-7 - Dutch pharmacogenetics working group (DPWG) guideline for the gene–drug interaction between UGT1A1 and irinotecan
E Hulshof et al, EJHG, November 28, 2022 - Fc?R and EGFR polymorphisms as predictive markers of cetuximab efficacy in metastatic colorectal cancer.
Inoue Yuka, et al. Molecular diagnosis & therapy 2014 10 (5) 541-8 - Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.
Lévesque Eric, et al. The Journal of pharmacology and experimental therapeutics 2013 4 (1) 95-101
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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
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