Effective August 1, 2024, this database was discontinued. All content will remain searchable and be preserved online for historical purposes only until 2029.
Sickle Cell Disease
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Last Posted: Jul 18, 2024
- A roadmap for affordable genetic medicines
- A Pharmacist-Managed Hydroxyurea Prescribing Protocol Improves Uptake and Optimization among Patients with Sickle Cell Disease.
Cameron Roessner et al. Adv Hematol 2024 20244753349 - Sickle cell disease and infertility risks: implications for counseling and care of affected girls and women.
Lydia H Pecker et al. Expert Rev Hematol 2024 - [Sickle cell disease in French Guiana: assessing 30 years of neonatal screening (1992-2021)].
Narcisse Elenga et al. Med Trop Sante Int 2024 4(1) - Update on the practice of premarital screening for sickle cell traits in Africa: a systematic review and meta-analysis.
Priscilla Peter Dilli et al. BMC Public Health 2024 24(1) 1467 - A Mixed-Methods Evaluation of a Project ECHO Program for the Evidence-Based Management of Sickle Cell Disease.
Cami Mosley et al. Int J Environ Res Public Health 2024 21(5) - Current and Future Therapeutics for Treating Patients with Sickle Cell Disease.
Mariam Barak et al. Cells 2024 13(10) - Barriers and facilitators to community acceptability of integrating point-of-care testing to screen for sickle cell disease in children in primary healthcare settings in rural Upper East Region of Northern Ghana.
Samuel T Chatio et al. PLoS One 2024 19(5) e0303520 - The highest-cost Medicaid enrollees with sickle cell disease had annual health care expenditures nearing $200 000.
Junelle Speller et al. Health Aff Sch 2024 2(4) qxae029 - A national postgraduate nurse practitioner and physician assistant fellowship in cystic fibrosis: An innovative approach to the provider shortage in complex and rare disease.
Cynthia J Brady et al. J Am Assoc Nurse Pract 2024 - Clinical Practice Patterns in Sickle Cell Disease Treatment: Disease-Modifying and Potentially Curative Therapies.
Luisanna M Sánchez et al. J Pediatr Hematol Oncol 2024 - Determination of birth prevalence of sickle cell disease using point of care test HemotypeSC™ at Rundu Hospital, Namibia.
Runyararo Mashingaidze Mano et al. BMC Pediatr 2024 24(1) 323 - Cost-Effectiveness of Lovotibeglogene Autotemcel (Lovo-Cel) Gene Therapy for Patients with Sickle Cell Disease and Recurrent Vaso-Occlusive Events in the United States.
William L Herring et al. Pharmacoeconomics 2024 - Long-term follow-up of children with sickle cell disease diagnosed by newborn screening in the Netherlands: Overview of morbidity and mortality.
Caroline Vuong et al. Am J Hematol 2024 - Exagamglogene Autotemcel for Severe Sickle Cell Disease
- Navigating equity in global access to genome therapy expanding access to potentially transformative therapies and benefiting those in need requires global policy changes.
Tsung-Ling Lee et al. Front Genet 2024 151381172 - Translational Research and Health Equity: Gene Therapies for Sickle Cell Disease as a Case Study.
Mary A Majumder et al. Ethics Hum Res 2024 46(3) 34-39 - Impact of Race, Socioeconomic Status, and Geography on Healthcare Outcomes for Children With Sickle Cell Disease in the United States: A Scoping Review
- Awareness of sickle cell disease among nursing undergraduates in Farasan: Its interference with malaria.
Shabihul Fatma Sayed et al. J Family Med Prim Care 2024 13(2) 589-599 - Evaluating thromboprophylaxis in the sickle cell disease population: Navigating the evidence gap.
Jennifer Davila et al. Br J Haematol 2024 - Current Methods of Newborn Screening Follow-Up for Sickle Cell Disease Are Highly Variable and without Quality Assurance: Results from the ENHANCE Study.
Najibah Galadanci et al. Int J Neonatal Screen 2024 10(1) - Iowa Newborn Screening Program Experience with Hemoglobinopathy Screening over the Last Two Decades and Its Increasing Global Relevance.
Ryan Jilek et al. Int J Neonatal Screen 2024 10(1) - Birth Prevalence of Sickle Cell Disease and County-Level Social Vulnerability - Sickle Cell Data Collection Program, 11 States, 2016-2020.
Mariam Kayle et al. MMWR Morb Mortal Wkly Rep 2024 3 (12) 248-254 - A scoping review exploring cure definitions and language for inherited hemoglobinopathies.
Marilyn S Baffoe-Bonnie et al. Genet Med Open 2024 2 - An International Learning Collaborative Phase 2 Trial for Haploidentical Bone Marrow Transplant in Sickle Cell Disease.
Adetola A Kassim et al. Blood 2024 - Current state of gene therapy in sickle cell disease.
Mei San Tang et al. Vox Sang 2024 - Dental caries in the permanent dentition and health-related quality of life among children and adolescents with sickle cell disease.
Vera Lúcia Duarte da Costa Mendes et al. Cien Saude Colet 2024 29(3) e06752023 - Genetic Information to Share with Parents when Newborn Screening Reveals the Presence of Sickle Cell Trait.
Narcisse Elenga et al. Int J Pediatr 2024 20248910397 - Perceptions and preferences for genetic testing for sickle cell disease or trait: a qualitative study in Cameroon, Ghana and Tanzania.
Nchangwi Syntia Munung et al. Eur J Hum Genet 2024 - Patient Perceptions on the Advancement of Noninvasive Prenatal Testing for Sickle Cell Disease among Black Women in the United States.
Shameka P Thomas et al. AJOB Empir Bioeth 2024 1-10 - An update review of new therapies in sickle cell disease: the prospects for drug combinations.
Sanne Lugthart et al. Expert Opin Pharmacother 2024 - Blood Spotlight Review on Gene Therapy for Sickle Cell Disease.
Edward J Benz et al. Blood 2024 - Comprehensive Care in Sickle Cell Disease.
Ananya Chandra et al. Pediatr Ann 2024 53(2) e43-e46 - Gene Therapy Versus Common Care for Eligible Individuals With Sickle Cell Disease in the United States : A Cost-Effectiveness Analysis.
Anirban Basu et al. Ann Intern Med 2024 - Burden of employment loss and absenteeism in adults and caregivers of children with sickle cell disease.
Rachel D'Amico Gordon et al. Blood Adv 2024 - CHOICES for sickle cell reproductive health: A protocol of a randomized preconception intervention model for a single gene disorder.
Diana J Wilkie et al. PLoS One 2023 18(12) e0294907 - Prevalence of sickle cell trait and needs assessment for uptake of sickle cell screening among secondary school students in Kampala City, Uganda.
Shamim Namukasa et al. PLoS One 2024 19(1) e0296119 - Newborn screening for sickle cell anemia in Antalya, Türkiye.
Zeynep Öztürk et al. Turk J Pediatr 2024 65(6) 959-963 - A comprehensive view of pregnancy in patients with sickle cell disease in high-income countries: the need for robust data and further decline in morbidity and mortality.
Laure Joseph et al. Lancet Haematol 2023 11(1) e75-e84 - Bridging the gaps in newborn screening programmes: Challenges and opportunities to detect haemoglobinopathies in Africa.
Seth Twum et al. Afr J Lab Med 2023 12(1) 2225 - Sickle Cell Disease Approvals Include First CRISPR Gene Editing Therapy
E Harris, JAMA, January 3, 2024 - Genomic medicine year in review: 2023.
Teri A Manolio et al. Am J Hum Genet 2023 12 (12) 1992-1995 - How CRISPR gene editing could help treat Alzheimer’s
T Thompson, Nature, December 11, 2023 - CRISPR 2.0: a new wave of gene editors heads for clinical trials Landmark approval of the first CRISPR therapy paves the way for treatments based on more efficient and more precise genome editors.
H Ledford, Nature, December 7, 2023 - In historic decision, FDA approves a CRISPR-based medicine for treatment of sickle cell disease
A Feurstein, StatNews, December 8, 2023 - An Ethical and Financial Obligation for Sickle Cell Disease Gene Therapy in the United States.
Austin Wesevich et al. Ann Intern Med 2023 - Genome editing for sickle cell disease: still time to correct?
Giulia Ceglie et al. Front Pediatr 2023 111249275 - Looking ahead: ethical and social challenges of somatic gene therapy for sickle cell disease in Africa.
Nchangwi Syntia Munung et al. Gene Ther 2023 - Pain Frequency and Health Care Utilization Patterns in Women with Sickle Cell Disease Experiencing Menstruation-Associated Pain Crises.
Catherine Segbefia et al. J Womens Health (Larchmt) 2023 - Challenges in screening for sickle cell disease among newborns from the tribal region of Palghar, Maharashtra during the COVID-19 pandemic.
Suchitra Surve et al. Indian J Med Res 2023 158(4) 378-383 - UK first to approve CRISPR treatment for diseases: what you need to know
C Wong. Nature. November 16, 2023 - Screening for haemoglobin disorders: One size may not fit all.
Lisa M Shook et al. Br J Haematol 2023 - A Newborn Screening Program for Sickle Cell Disease in Murcia (Spain).
María Sánchez-Villalobos et al. Int J Neonatal Screen 2023 9(4) - Impact of Genetic Variations on Thromboembolic Risk in Saudis with Sickle Cell Disease.
Mohammad A Alshabeeb et al. Genes (Basel) 2023 14(10) - Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis.
Justin K Kirkham et al. JAMA Netw Open 2023 10 (10) e2337484 - Implementation of Hospital-Based Sickle Cell Newborn Screening and Follow-Up Programs in Haiti.
Ofelia A Alvarez et al. Blood Adv 2023 - Outcomes and long-term effects of hematopoietic stem cell transplant in sickle cell disease.
Zaina Inam et al. Expert Rev Hematol 2023 - Current challenges and new approaches to implementing optimal management of sickle cell disease in sub-Saharan Africa.
Mwashungi Ally et al. Semin Hematol 2023 - Potential for a large-scale newborn screening strategy for sickle cell disease in Mali: A comparative diagnostic performance study of two rapid diagnostic tests (SickleScan® and HemotypeSC®) on cord blood.
Aldiouma Guindo et al. Br J Haematol 2023 - Gene therapy for Hemoglobinopathies.
Maria Rosa Lidonnici et al. Hum Gene Ther 2023 - Preimplantation genetic testing for sickle cell disease: a cost-effectiveness analysis.
Joshua C Combs et al. F S Rep 2023 4(3) 300-307 - Pregnant and Living with Sickle Cell Disease: A Push for Better Outcomes
NIH, September 2023 - Evaluation of newborn screening in the state of Mato Grosso from 2005 to 2019.
Roseli Divino Costa et al. Rev Paul Pediatr 2023 42e2022161 - A Proclamation on National Sickle Cell Awareness Month, 2023
The White House, September 2023. - CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease.
Akshay Sharma et al. N Engl J Med 2023 8 (9) 820-832 - Newborn screening for sickle cell disease in Butembo and Beni: a pilot experience in a highland region of the Democratic Republic of Congo.
Mupenzi Mumbere et al. Pan Afr Med J 2023 4556 - Sickle cell disease in Ontario, Canada: an epidemiologic profile based on health administrative data.
Jacob Pendergrast et al. CMAJ Open 2023 11(4) E725-E733 - Genetic counseling in sickle cell disease: Insights from the Indian tribal population.
Pooja Aggarwal et al. J Community Genet 2023 8 - Spreading awareness of sickle cell trait and its possible complications A better understanding of the trait is crucial for both patients and providers
M Shaniqua, Sickle Cell New, August 2023 - Barriers and Facilitators of Premarital Genetic Counseling for Sickle Cell Disease in Northern Nigeria.
Aisha A Galadanci et al. J Pediatr Hematol Oncol 2023 45(6) e716-e722 - Base-edited gene therapies ‘may be superior’ for sickle cell disease
Healio, July 2023 - Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission.
Frédéric B Piel et al. Lancet Haematol 2023 - Sickle cell disease in the Caribbean: progress in newborn screening, clinical care, and research through collaboration.
Jennifer Knight-Madden et al. Lancet Haematol 2023 - Sickle cell disease landscape and challenges in the EU: the ERN-EuroBloodNet perspective.
María Del Mar Mañú Pereira et al. Lancet Haematol 2023 - The Importance of Patient-Doctor Relationships With Sickle Cell Disease
L Poret, WebMD, July 2023 - Sickle cell cures are coming. African children can’t be left behind
JK Iyer, Statnews, July 2023 - Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021.
et al. Lancet Haematol 2023 6 - Social determinants of health: the next frontier for improving care and outcomes in sickle cell disease
JS Porter et al, Lancet Heamtology, July 2023 - Ending the burden of sickle cell disease in Africa
MR Motti et al, Lancet Hematology, July 2023 - The Lancet Haematology Commission on sickle cell disease: key recommendations
The Lancet Haematology Commission on sickle cell disease: Lancet Hematology, July 2023
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About HLBS-PopOmics
HLBS-PopOmics is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other materials that address the translation of genomic and other precision health discoveries into improved health care and prevention related to Heart and Vascular Diseases(H), Lung Diseases(L), Blood Diseases(B), and Sleep Disorders(S)...more
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Mensah GA, Yu W, Barfield WL, Clyne M, Engelgau MM, Khoury MJ. HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders. Genet Med. 2018 Sep 10. doi: 10.1038/s41436-018-0118-1
Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
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