Human Genome Epidemiology Literature Finder
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Records 1 - 19 (of 19 Records) |
| Query Trace: Disease and meta-analysis and PCSK9[original query] |
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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
The Journal of clinical investigation 2022 10 132 (24): . Hindy George, Tyrrell Daniel J, Vasbinder Alexi, Wei Changli, Presswalla Feriel, Wang Hui, Blakely Pennelope, Ozel Ayse Bilge, Graham Sarah, Holton Grace H, Dowsett Joseph, Fahed Akl C, Amadi Kingsley-Michael, Erne Grace K, Tekmulla Annika, Ismail Anis, Launius Christopher, Sotoodehnia Nona, Pankow James S, Thørner Lise Wegner, Erikstrup Christian, Pedersen Ole Birger, Banasik Karina, Brunak Søren, Ullum Henrik, Eugen-Olsen Jesper, Ostrowski Sisse Rye, , Haas Mary E, Nielsen Jonas B, Lotta Luca A, , Engström Gunnar, Melander Olle, Orho-Melander Marju, Zhao Lili, Murthy Venkatesh L, Pinsky David J, Willer Cristen J, Heckbert Susan R, Reiser Jochen, Goldstein Daniel R, Desch Karl C, Hayek Salim |
| Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
Nature genetics 2008 Feb 40 (2): 161-9. Willer Cristen J, Sanna Serena, Jackson Anne U, Scuteri Angelo, Bonnycastle Lori L, Clarke Robert, Heath Simon C, Timpson Nicholas J, Najjar Samer S, Stringham Heather M, Strait James, Duren William L, Maschio Andrea, Busonero Fabio, Mulas Antonella, Albai Giuseppe, Swift Amy J, Morken Mario A, Narisu Narisu, Bennett Derrick, Parish Sarah, Shen Haiqing, Galan Pilar, Meneton Pierre, Hercberg Serge, Zelenika Diana, Chen Wei-Min, Li Yun, Scott Laura J, Scheet Paul A, Sundvall Jouko, Watanabe Richard M, Nagaraja Ramaiah, Ebrahim Shah, Lawlor Debbie A, Ben-Shlomo Yoav, Davey-Smith George, Shuldiner Alan R, Collins Rory, Bergman Richard N, Uda Manuela, Tuomilehto Jaakko, Cao Antonio, Collins Francis S, Lakatta Edward, Lathrop G Mark, Boehnke Michael, Schlessinger David, Mohlke Karen L, Abecasis Gonçalo |
| Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis. Clinical biochemistry 2013 Feb . Zhang L, Yuan F, Liu P, Fei L, Huang Y, Xu L, Hao L, Qiu X, Le Y, Yang X, Xu W, Huang X, Ye M, Zhou J, Lian J, Duan S |
| Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations. Journal of medical genetics 2014 Aug 51 (8): 537-44. Futema Marta, Plagnol Vincent, Li KaWah, Whittall Ros A, Neil H Andrew W, Seed Mary, , Bertolini Stefano, Calandra Sebastiano, Descamps Olivier S, Graham Colin A, Hegele Robert A, Karpe Fredrik, Durst Ronen, Leitersdorf Eran, Lench Nicholas, Nair Devaki R, Soran Handrean, Van Bockxmeer Frank M, , Humphries Steve |
| Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians. The Journal of clinical endocrinology and metabolism 2015 Feb 100 (2): E345-9. Tsai Ching-Wei, North Kari E, Tin Adrienne, Haack Karin, Franceschini Nora, Saroja Voruganti V, Laston Sandy, Zhang Ying, Best Lyle G, MacCluer Jean W, Beaty Terri H, Navas-Acien Ana, Kao W H Linda, Howard Barbara |
| The Influence of OLR1 and PCSK9 Gene Polymorphisms on Ischemic Stroke: Evidence from a Meta-Analysis. Scientific reports 2015 5 18224. Au Anthony, Griffiths Lyn R, Cheng Kian-Kai, Wee Kooi Cheah, Irene Looi, Keat Wei L |
| The associations between proprotein convertase subtilisin/kexin type 9 E670G polymorphism and the risk of coronary artery disease and serum lipid levels: a meta-analysis. Lipids in health and disease 2015 14 (1): 149. Cai Gaojun, Zhang Bifeng, Shi Ganwei, Weng Weijin, Ma Chunyan, Song Yanbin, Zhang |
| Coding-sequence variants are associated with blood lipid levels in 14,473 Chinese. Human molecular genetics 2016 Aug . Lu Xiangfeng, Li Jun, Li Huaixing, Chen Yang, Wang Laiyuan, He Meian, Wang Yiqin, Sun Liang, Hu Yao, Huang Jianfeng, Wang Feijie, Liu Xuezhen, Chen Shufeng, Yu Kuai, Yang Xueli, Mo Zengnan, Lin Xu, Wu Tangchun, Gu Dongfe |
| Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. JAMA 2016 Oct 316 (13): 1383-1391. Lotta Luca A, Sharp Stephen J, Burgess Stephen, Perry John R B, Stewart Isobel D, Willems Sara M, Luan Jian'an, Ardanaz Eva, Arriola Larraitz, Balkau Beverley, Boeing Heiner, Deloukas Panos, Forouhi Nita G, Franks Paul W, Grioni Sara, Kaaks Rudolf, Key Timothy J, Navarro Carmen, Nilsson Peter M, Overvad Kim, Palli Domenico, Panico Salvatore, Quirós Jose-Ramón, Riboli Elio, Rolandsson Olov, Sacerdote Carlotta, Salamanca-Fernandez Elena, Slimani Nadia, Spijkerman Annemieke M W, Tjonneland Anne, Tumino Rosario, van der A Daphne L, van der Schouw Yvonne T, McCarthy Mark I, Barroso Inês, O'Rahilly Stephen, Savage David B, Sattar Naveed, Langenberg Claudia, Scott Robert A, Wareham Nicholas |
| PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. Circulation. Cardiovascular genetics 2017 8 10 (4): e001632. Kent Shia T, Rosenson Robert S, Avery Christy L, Chen Yii-Der I, Correa Adolfo, Cummings Steven R, Cupples L Adrienne, Cushman Mary, Evans Daniel S, Gudnason Vilmundur, Harris Tamara B, Howard George, Irvin Marguerite R, Judd Suzanne E, Jukema J Wouter, Lange Leslie, Levitan Emily B, Li Xiaohui, Liu Yongmei, Post Wendy S, Postmus Iris, Psaty Bruce M, Rotter Jerome I, Safford Monika M, Sitlani Colleen M, Smith Albert V, Stewart James D, Trompet Stella, Sun Fangui, Vasan Ramachandran S, Woolley J Michael, Whitsel Eric A, Wiggins Kerri L, Wilson James G, Muntner Pa |
| What is the impact of PCSK9 rs505151 and rs11591147 polymorphisms on serum lipids level and cardiovascular risk: a meta-analysis. Lipids in health and disease 2017 Jun 16 (1): 111. Qiu Chengfeng, Zeng Pingyu, Li Xiaohui, Zhang Zhen, Pan Bingjie, Peng Zhou Y F, Li Yapei, Ma Yeshuo, Leng Yiping, Chen Ruifa |
| Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke. European heart journal 2017 Jul . Hopewell Jemma C, Malik Rainer, Valdés-Márquez Elsa, Worrall Bradford B, Collins Rory, |
| Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
Nature genetics 2018 Oct . Klarin Derek, Damrauer Scott M, Cho Kelly, Sun Yan V, Teslovich Tanya M, Honerlaw Jacqueline, Gagnon David R, DuVall Scott L, Li Jin, Peloso Gina M, Chaffin Mark, Small Aeron M, Huang Jie, Tang Hua, Lynch Julie A, Ho Yuk-Lam, Liu Dajiang J, Emdin Connor A, Li Alexander H, Huffman Jennifer E, Lee Jennifer S, Natarajan Pradeep, Chowdhury Rajiv, Saleheen Danish, Vujkovic Marijana, Baras Aris, Pyarajan Saiju, Di Angelantonio Emanuele, Neale Benjamin M, Naheed Aliya, Khera Amit V, Danesh John, Chang Kyong-Mi, Abecasis Gonçalo, Willer Cristen, Dewey Frederick E, Carey David J, , , , , Concato John, Gaziano J Michael, O'Donnell Christopher J, Tsao Philip S, Kathiresan Sekar, Rader Daniel J, Wilson Peter W F, Assimes Themistocles |
| PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort. PloS one 2020 11 15 (11): e0239752. Small Aeron M, Huffman Jennifer E, Klarin Derek, Lynch Julie A, Assimes Themistocles, DuVall Scott, Sun Yan V, Shere Labiba, Natarajan Pradeep, Gaziano Michael, Rader Daniel J, Wilson Peter W F, Tsao Philip S, Chang Kyong-Mi, Cho Kelly, O'Donnell Christopher J, Casas Juan P, Damrauer Scott M, |
| PCSK9 Gene E670G Polymorphism and Coronary Artery Disease: An Updated Meta-Analysis of 5,484 Subjects. Frontiers in cardiovascular medicine 2020 11 7 582865. Li Yan-Yan, Wang Hui, Yang Xin-Xing, Geng Hong-Yu, Gong Ge, Lu Xin-Zhe |
| Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2.
Human molecular genetics 2021 10 31 (6): 999-1011. Pott Janne, Gådin Jesper R, Theusch Elizabeth, Kleber Marcus E, Delgado Graciela E, Kirsten Holger, Hauck Stefanie M, Burkhardt Ralph, Scharnagl Hubert, Krauss Ronald M, Loeffler Markus, März Winfried, Thiery Joachim, Silveira Angela, Van't Hooft Ferdinand M, Scholz Mark |
| PCSK9 inhibitors and osteoporosis: mendelian randomization and meta-analysis. BMC musculoskeletal disorders 2024 7 25 (1): 548. Ding-Qiang Chen, Wen-Bin Xu, Ke-Yi Xiao, Zhi-Qiang Que, Jin-Yi Feng, Nai-Kun Sun, Di-Xin Cai, Gang R |
| PCSK9 and Lipid Metabolism: Genetic Variants, Current Therapies, and Cardiovascular Outcomes. Cardiovascular drugs and therapy 2024 6 . Daniela Grejtakova, Iveta Boronova, Jarmila Bernasovska, Stefano Bellos |
| Effect of the PCSK9 R46L genetic variant on plasma insulin and glucose levels, risk of diabetes mellitus and cardiovascular disease: A meta-analysis. Nutrition, metabolism, and cardiovascular diseases : NMCD 2024 5 . Sen Liu, Jindong Wan, Dan Wang, Yi Yang, Jie Fang, Tao Luo, Dengpan Liang, Jun Hu, Jixin Hou, Peijian Wa |
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