Human Genome Epidemiology Literature Finder
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Records 1 - 30 (of 35 Records) |
| Query Trace: Disease and NPC1L1[original query] |
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| Inactivating mutations in NPC1L1 and protection from coronary heart disease. The New England journal of medicine 2014 Nov 371 (22): 2072-82. , Stitziel Nathan O, Won Hong-Hee, Morrison Alanna C, Peloso Gina M, Do Ron, Lange Leslie A, Fontanillas Pierre, Gupta Namrata, Duga Stefano, Goel Anuj, Farrall Martin, Saleheen Danish, Ferrario Paola, König Inke, Asselta Rosanna, Merlini Piera A, Marziliano Nicola, Notarangelo Maria Francesca, Schick Ursula, Auer Paul, Assimes Themistocles L, Reilly Muredach, Wilensky Robert, Rader Daniel J, Hovingh G Kees, Meitinger Thomas, Kessler Thorsten, Kastrati Adnan, Laugwitz Karl-Ludwig, Siscovick David, Rotter Jerome I, Hazen Stanley L, Tracy Russell, Cresci Sharon, Spertus John, Jackson Rebecca, Schwartz Stephen M, Natarajan Pradeep, Crosby Jacy, Muzny Donna, Ballantyne Christie, Rich Stephen S, O'Donnell Christopher J, Abecasis Goncalo, Sunyaev Shamil, Nickerson Deborah A, Buring Julie E, Ridker Paul M, Chasman Daniel I, Austin Erin, Ye Zi, Kullo Iftikhar J, Weeke Peter E, Shaffer Christian M, Bastarache Lisa A, Denny Joshua C, Roden Dan M, Palmer Colin, Deloukas Panos, Lin Dan-Yu, Tang Zheng-zheng, Erdmann Jeanette, Schunkert Heribert, Danesh John, Marrugat Jaume, Elosua Roberto, Ardissino Diego, McPherson Ruth, Watkins Hugh, Reiner Alex P, Wilson James G, Altshuler David, Gibbs Richard A, Lander Eric S, Boerwinkle Eric, Gabriel Stacey, Kathiresan Sek |
| Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease. European heart journal 2015 Jul 36 (25): 1601-8. Lauridsen Bo Kobberø, Stender Stefan, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjærg-Hansen An |
| Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study. Journal of the American College of Cardiology 2015 Apr 65 (15): 1552-61. Ference Brian A, Majeed Faisal, Penumetcha Raju, Flack John M, Brook Robert |
| Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. JAMA 2016 Oct 316 (13): 1383-1391. Lotta Luca A, Sharp Stephen J, Burgess Stephen, Perry John R B, Stewart Isobel D, Willems Sara M, Luan Jian'an, Ardanaz Eva, Arriola Larraitz, Balkau Beverley, Boeing Heiner, Deloukas Panos, Forouhi Nita G, Franks Paul W, Grioni Sara, Kaaks Rudolf, Key Timothy J, Navarro Carmen, Nilsson Peter M, Overvad Kim, Palli Domenico, Panico Salvatore, Quirós Jose-Ramón, Riboli Elio, Rolandsson Olov, Sacerdote Carlotta, Salamanca-Fernandez Elena, Slimani Nadia, Spijkerman Annemieke M W, Tjonneland Anne, Tumino Rosario, van der A Daphne L, van der Schouw Yvonne T, McCarthy Mark I, Barroso Inês, O'Rahilly Stephen, Savage David B, Sattar Naveed, Langenberg Claudia, Scott Robert A, Wareham Nicholas |
| Identification and characterization of NPC1L1 variants in Uygur and Kazakh with extreme low-density lipoprotein cholesterol. Biochemical and biophysical research communications 2016 Sep . Yuan Qinghua, Fu Zhenyan, Wei Jian, Li Pei-Shan, Miao Hong-Hua, Qu Yu-Xiu, Xu Jie, Qin Jie, Li Bo-Liang, Song Bao-Liang, Ma Yito |
| The NPC1L1 Polymorphism 1679C>G Is Associated with Gallstone Disease in Chinese Patients. PloS one 2016 11 (1): e0147562. Wu Jian, Cui Wei, Cai Qu, Fei Jian, Zhang Sheng-Dao, Han Tian-Quan, Hu Hai, Jiang Zhao-Y |
| Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer. International journal of epidemiology 2017 11 46 (6): 1777-1785. Kobberø Lauridsen Bo, Stender Stefan, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjærg-Hansen An |
| Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study. The international journal of neuropsychopharmacology 2018 Jul . Alghamdi Jahad, Matou-Nasri Sabine, Alghamdi Faisal, Alghamdi Saleh, Alfadhel Majid, Padmanabhan Sando |
| Genetic polymorphism of sterol transporters in children with future gallstones. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2018 5 50 (9): 954-960. Nissinen Markku J, Pitkänen Niina, Simonen Piia, Gylling Helena, Viikari Jorma, Raitakari Olli, Lehtimäki Terho, Juonala Markus, Pakarinen Mikko |
| Unexplained reciprocal regulation of diabetes and lipoproteins. Current opinion in lipidology 2018 5 29 (3): 186-193. Higuchi Sei, Izquierdo M Concepción, Haeusler Rebecca |
| Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes. JAMA cardiology 2018 Oct 3 (10): 957-966. Lotta Luca A, Stewart Isobel D, Sharp Stephen J, Day Felix R, Burgess Stephen, Luan Jian'an, Bowker Nicholas, Cai Lina, Li Chen, Wittemans Laura B L, Kerrison Nicola D, Khaw Kay-Tee, McCarthy Mark I, O'Rahilly Stephen, Scott Robert A, Savage David B, Perry John R B, Langenberg Claudia, Wareham Nicholas |
| Lipid lowering and Alzheimer disease risk: A mendelian randomization study. Annals of neurology 2019 11 87 (1): 30-39. Williams Dylan M, Finan Chris, Schmidt Amand F, Burgess Stephen, Hingorani Aroon |
| Common gene variants in ASGR1 gene locus associate with reduced cardiovascular risk in absence of pleiotropic effects. Atherosclerosis 2020 Jul 306 15-21. Ali Lubna, Cupido Arjen J, Rijkers Maaike, Hovingh G Kees, Holleboom Adriaan G, Dallinga-Thie Geesje M, Stroes Erik S G, van den Boogert Marjolein A |
| Association of NPC1L1 and HMGCR Gene Polymorphisms with Major Adverse Cardiac and Cerebrovascular Events in Patients with Three-Vessel Disease. Human gene therapy 2020 Nov . Zhao Xueyan, Li Jiawen, Tang Xiaofang, Liu Ru, Xu Jingjing, Xu Lianjun, Jiang Lin, Huang Keyong, Tian Jian, Feng Xingxing, Wu Yajie, Zhang Yin, Wang Dong, Sun Kai, Xu Bo, Zhao Wei, Hui Rutai, Gao Runlin, Song Lei, Yuan Jinqi |
| Effect of NPC1L1 and HMGCR Genetic Variants With Premature Triple-Vessel Coronary Disease. Frontiers in cardiovascular medicine 2021 12 8 704501. Zhao Xueyan, Xu Jingjing, Tang Xiaofang, Huang Keyong, Li Jiawen, Liu Ru, Jiang Lin, Zhang Yin, Wang Dong, Sun Kai, Xu Bo, Zhao Wei, Hui Rutai, Gao Runlin, Song Lei, Yuan Jinqi |
| Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple-vessel disease patients. The journal of gene medicine 2022 Sep 24 (9): e3445. Zhao Xueyan, Tang Xiaofang, Xu Jingjing, Liu Ru, Huang Keyong, Li Jiawen, Li Yulong, Jiang Lin, Xu Lianjun, Zhang Yin, Wang Dong, Hui Rutai, Gao Runlin, Song Lei, Yuan Jinqi |
| Lipids, Apolipoproteins, Statins, and Intracerebral Hemorrhage: A Mendelian Randomization Study. Annals of neurology 2022 6 92 (3): 390-399. Yu Zhou, Zhang Linjing, Zhang Gan, Xia Kailin, Yang Qiong, Huang Tao, Fan Dongshe |
| Common variant p.D19H of the hepatobiliary sterol transporter ABCG8 increases the risk of gallstones in children. Liver international : official journal of the International Association for the Study of the Liver 2022 Feb . Krawczyk Marcin, Niewiadomska Olga, Jankowska Irena, Jankowski Krzysztof, Wi?ckowski Sebastian, Lebensztejn Dariusz, Wi?cek Sabina, Gozdowska Jolanta, Ku?aga Zbigniew, Weber Susanne N, Lütjohann Dieter, Lammert Frank, Socha Pio |
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PLoS biology 2022 2 20 (2): e3001547. Richardson Tom G, Leyden Genevieve M, Wang Qin, Bell Joshua A, Elsworth Benjamin, Davey Smith George, Holmes Michael |
| Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.
Nature communications 2022 1 13 (1): 143. Scholz Markus, Horn Katrin, Pott Janne, Gross Arnd, Kleber Marcus E, Delgado Graciela E, Mishra Pashupati Prasad, Kirsten Holger, Gieger Christian, Müller-Nurasyid Martina, Tönjes Anke, Kovacs Peter, Lehtimäki Terho, Raitakari Olli, Kähönen Mika, Gylling Helena, Baber Ronny, Isermann Berend, Stumvoll Michael, Loeffler Markus, März Winfried, Meitinger Thomas, Peters Annette, Thiery Joachim, Teupser Daniel, Ceglarek U |
| Association between the use of lipid-lowering drugs and the risk of inflammatory bowel disease. European journal of clinical investigation 2023 7 e14067. Xuxu Liu, Zhenyi Lv, Zhihong Xie, Qiang Wang, Wenchao Yao, Jingjing Yu, Qingxu Jing, Xianzhi Meng, Biao Ma, Dongbo Xue, Chenjun H |
| HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins. BMC cardiovascular disorders 2023 6 23 (1): 317. Jiawen Li, Xiaofang Tang, Jingjing Xu, Ru Liu, Lin Jiang, Lianjun Xu, Jian Tian, Xinxing Feng, Yajie Wu, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan, Xueyan Zh |
| Genetically instrumented LDL-cholesterol lowering and multiple disease outcomes: a Mendelian randomisation phenome-wide association study in the UK Biobank. British journal of clinical pharmacology 2023 5 . Kitty Pham, Anwar Mulugeta, Amanda Lumsden, Elina Hypp?n |
| Causal association between lipid-lowering drugs and female reproductive endocrine diseases: a drug-targeted Mendelian randomization study. Frontiers in endocrinology 2023 11 14 1295412. Jing Zhao, Runfang Wang, Liyun Song, Hua Han, Pei Wang, Yuan Zhao, Yunxia Zhang, Hongzhen Zha |
| Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study. JAMA dermatology 2023 1 . Zhao Sizheng Steven, Yiu Zenas Z N, Barton Anne, Bowes Jo |
| Novel insights into the association between genetically proxied inhibition of proprotein convertase subtilisin/kexin type 9 and risk of sarcopenia. Journal of cachexia, sarcopenia and muscle 2024 9 . Hongyan Jiang, Lulu Li, Xue Zhang, Jia He, Chuanhuai Chen, Ruimin Sun, Ying Chen, Lijuan Xia, Lei Wen, Yunxiang Chen, Junxiu Liu, Lijiang Zhang, Wanqiang |
| Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study. BMC cancer 2024 5 24 (1): 602. Lusheng Miao, Taosheng Miao, Ying Zhang, Jin H |
| Association of lipid-lowering drugs with the risk of type 2 diabetes and its complications: a mendelian randomized study. Diabetology & metabolic syndrome 2024 10 16 (1): 240. Yue-Yang Zhang, Bing-Xue Chen, Qin W |
| Association between lipid-lowering agents with intervertebral disc degeneration, sciatica and low back pain: a drug-targeted mendelian randomized study and cross-sectional observation. Lipids in health and disease 2024 10 23 (1): 327. Chenxu Liu, Xinqiao Chu, Yaning Biao, Qiubai Jin, Yufang Zhang, Ya Gao, Shuo Feng, Jizheng Ma, Yixin Zha |
| Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease. BMC medical genomics 2024 1 17 (1): 22. Yulong Li, Jiawen Li, Xiaofang Tang, Jingjing Xu, Ru Liu, Lin Jiang, Jian Tian, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan, Xueyan Zh |
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