Human Genome Epidemiology Literature Finder
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Records 1 - 30 (of 81 Records) |
| Query Trace: Disease and HMGCR[original query] |
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| Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple-vessel disease patients. The journal of gene medicine 2022 Sep 24 (9): e3445. Zhao Xueyan, Tang Xiaofang, Xu Jingjing, Liu Ru, Huang Keyong, Li Jiawen, Li Yulong, Jiang Lin, Xu Lianjun, Zhang Yin, Wang Dong, Hui Rutai, Gao Runlin, Song Lei, Yuan Jinqi |
| Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function. Journal of the American College of Cardiology 2022 8 80 (7): 653-662. Rosoff Daniel B, Bell Andrew S, Jung Jeesun, Wagner Josephin, Mavromatis Lucas A, Lohoff Falk |
| Cancer associated autoantibodies in idiopathic inflammatory myopathies: A retrospective cohort from a single center in China. Medicina clinica 2022 7 160 (1): 10-16. Zhao Yin, Su Haiyuan, Yin Xiaoyang, Hou Hou, Wang Ying'ai, Xu Yong, Li Xin, Zhang Nang, Sun Wenwen, Wei W |
| Lipids, Apolipoproteins, Statins, and Intracerebral Hemorrhage: A Mendelian Randomization Study. Annals of neurology 2022 6 92 (3): 390-399. Yu Zhou, Zhang Linjing, Zhang Gan, Xia Kailin, Yang Qiong, Huang Tao, Fan Dongshe |
| Association of immune-mediated necrotizing myopathy with HLA polymorphisms. HLA 2022 12 . Ohnuki Yuko, Suzuki Shigeaki, Uruha Akinori, Oyama Munenori, Suzuki Shingo, Kulski Jerzy K, Nishino Ichizo, Shiina Takas |
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PLoS biology 2022 2 20 (2): e3001547. Richardson Tom G, Leyden Genevieve M, Wang Qin, Bell Joshua A, Elsworth Benjamin, Davey Smith George, Holmes Michael |
| Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.
Nature communications 2022 1 13 (1): 143. Scholz Markus, Horn Katrin, Pott Janne, Gross Arnd, Kleber Marcus E, Delgado Graciela E, Mishra Pashupati Prasad, Kirsten Holger, Gieger Christian, Müller-Nurasyid Martina, Tönjes Anke, Kovacs Peter, Lehtimäki Terho, Raitakari Olli, Kähönen Mika, Gylling Helena, Baber Ronny, Isermann Berend, Stumvoll Michael, Loeffler Markus, März Winfried, Meitinger Thomas, Peters Annette, Thiery Joachim, Teupser Daniel, Ceglarek U |
| Genetic variation in targets of lipid-lowering drugs and amyotrophic lateral sclerosis risk: a Mendelian randomization study. Amyotrophic lateral sclerosis & frontotemporal degeneration 2023 9 1-10. Zhiguang Li, Mei Tian, Hongning Jia, Xin Li, Qi Liu, Xiaomeng Zhou, Rui Li, Hui Dong, Yaling L |
| Assessing the impact of PCSK9 and HMGCR inhibition on liver function: drug-target Mendelian Randomization analyses in 4 ancestries. Cellular and molecular gastroenterology and hepatology 2023 9 . Daniel B Rosoff, Andrew S Bell, Josephin Wagner, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Falk W Loho |
| Causal relationship between PCSK9 inhibitor and autoimmune diseases: a drug target Mendelian randomization study. Arthritis research & therapy 2023 8 25 (1): 148. Weijia Xie, Jiaxin Li, Hao Du, Jian X |
| Association between the use of lipid-lowering drugs and the risk of inflammatory bowel disease. European journal of clinical investigation 2023 7 e14067. Xuxu Liu, Zhenyi Lv, Zhihong Xie, Qiang Wang, Wenchao Yao, Jingjing Yu, Qingxu Jing, Xianzhi Meng, Biao Ma, Dongbo Xue, Chenjun H |
| HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins. BMC cardiovascular disorders 2023 6 23 (1): 317. Jiawen Li, Xiaofang Tang, Jingjing Xu, Ru Liu, Lin Jiang, Lianjun Xu, Jian Tian, Xinxing Feng, Yajie Wu, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan, Xueyan Zh |
| Genetically instrumented LDL-cholesterol lowering and multiple disease outcomes: a Mendelian randomisation phenome-wide association study in the UK Biobank. British journal of clinical pharmacology 2023 5 . Kitty Pham, Anwar Mulugeta, Amanda Lumsden, Elina Hypp?n |
| Association of HMGCR inhibition with rheumatoid arthritis: a Mendelian randomization and colocalization study. Frontiers in endocrinology 2023 12 14 1272167. Li Ma, Yufei Du, Chao Ma, Ming L |
| Causal association between lipid-lowering drugs and female reproductive endocrine diseases: a drug-targeted Mendelian randomization study. Frontiers in endocrinology 2023 11 14 1295412. Jing Zhao, Runfang Wang, Liyun Song, Hua Han, Pei Wang, Yuan Zhao, Yunxia Zhang, Hongzhen Zha |
| Association between HMGCR, CRP, and CETP gene polymorphisms and metabolic/inflammatory serum profile in healthy adolescents. Journal of translational medicine 2023 10 21 (1): 718. Benedetta Perrone, Paola Ruffo, Giuseppina Augimeri, Diego Sisci, Maria Stefania Sinicropi, Giovanni Tripepi, Corrado Mammì, Daniela Bonofiglio, Francesca Luisa Confor |
| Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study. JAMA dermatology 2023 1 . Zhao Sizheng Steven, Yiu Zenas Z N, Barton Anne, Bowes Jo |
| Pharmacogenetics of anxiety and depression in Alzheimer's disease. Pharmacogenomics 2023 1 24 (1): 27-57. Cacabelos Ramón, Carril Juan C, Corzo Lola, Pego Rocío, Cacabelos Natalia, Alcaraz Margarita, Muñiz Adriana, Martínez-Iglesias Olaia, Naidoo Vinogr |
| Novel insights into the association between genetically proxied inhibition of proprotein convertase subtilisin/kexin type 9 and risk of sarcopenia. Journal of cachexia, sarcopenia and muscle 2024 9 . Hongyan Jiang, Lulu Li, Xue Zhang, Jia He, Chuanhuai Chen, Ruimin Sun, Ying Chen, Lijuan Xia, Lei Wen, Yunxiang Chen, Junxiu Liu, Lijiang Zhang, Wanqiang |
| Absence of Pathogenic Mutations and Strong Association With HLA-DRB1*11:01 in Statin-Naïve Early-Onset Anti-HMGCR Necrotizing Myopathy. Neurology(R) neuroimmunology & neuroinflammation 2024 8 11 (5): e200285. Laura Llansó, Alba Segarra-Casas, Cristina Domínguez-González, Edoardo Malfatti, Solange Kapetanovic, Benjamín Rodríguez-Santiago, Oscar de la Calle, Rosa Blanco, Amelia Dobrescu, Andrés Nascimento-Osorio, Andrés Paipa, Aurelio Hernandez-Lain, Cristina Jou, Anaís Mariscal, Laura González-Mera, Ana Arteche, Cinta Lleixà, Marta Caballero-Ávila, Álvaro Carbayo, Ana Vesperinas, Luis Querol, Eduard Gallardo, Montse Oli |
| Lipids, Apolipoproteins, Lipid-Lowering Drugs, and the Risk of Cerebral Small Vessel Disease: A Mendelian Randomization Study. Journal of the American Heart Association 2024 8 13 (16): e032409. Yi Xie, Shuai Liu, Xinyue Wang, Hao Huang, Minghuan Wang, Wensheng Qu, Zhiyuan Yu, Wei Wang, Xiang L |
| New target-HMGCR inhibitors for the treatment of primary sclerosing cholangitis: A drug Mendelian randomization study. Open medicine (Warsaw, Poland) 2024 7 19 (1): 20240994. Jie Zhou, Yixin Xu, Haitao Wang, Zhilin L |
| PCSK9 inhibitors and osteoporosis: mendelian randomization and meta-analysis. BMC musculoskeletal disorders 2024 7 25 (1): 548. Ding-Qiang Chen, Wen-Bin Xu, Ke-Yi Xiao, Zhi-Qiang Que, Jin-Yi Feng, Nai-Kun Sun, Di-Xin Cai, Gang R |
| Causal relationship between PCSK9 inhibitor and common neurodegenerative diseases: A drug target Mendelian randomization study. Brain and behavior 2024 6 14 (6): e3543. Qiang Huang, Qin Zhang, Bei C |
| Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study. BMC cancer 2024 5 24 (1): 602. Lusheng Miao, Taosheng Miao, Ying Zhang, Jin H |
| Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancers. Discover oncology 2024 12 15 (1): 798. Hengchang Liang, Chunling Tang, Yue Sun, Mingwei Wang, Tong Tong, Qinquan Gao, Hui Xie, Tao T |
| Association of lipid-lowering drugs with the risk of type 2 diabetes and its complications: a mendelian randomized study. Diabetology & metabolic syndrome 2024 10 16 (1): 240. Yue-Yang Zhang, Bing-Xue Chen, Qin W |
| Association between lipid-lowering agents with intervertebral disc degeneration, sciatica and low back pain: a drug-targeted mendelian randomized study and cross-sectional observation. Lipids in health and disease 2024 10 23 (1): 327. Chenxu Liu, Xinqiao Chu, Yaning Biao, Qiubai Jin, Yufang Zhang, Ya Gao, Shuo Feng, Jizheng Ma, Yixin Zha |
| Association of HMGCR rs17671591 and rs3761740 with lipidemia and statin response in Uyghurs and Han Chinese. PeerJ 2024 10 12 e18144. Ziyang Liu, Yang Zhou, Menglong Jin, Shuai Liu, Sen Liu, Kai Yang, Huayin Li, Sifu Luo, Subinuer Jureti, Mengwei Wei, Zhenyan |
| Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease. BMC medical genomics 2024 1 17 (1): 22. Yulong Li, Jiawen Li, Xiaofang Tang, Jingjing Xu, Ru Liu, Lin Jiang, Jian Tian, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan, Xueyan Zh |
- Page last reviewed:Feb 1, 2024
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