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Hot Topics of the Day|PHGKB
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06/17/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Do Your Genes Place You At High Risk For COVID-19?
E Matloff, Forbes, June 17, 2020

Could our genes factor into who gets COVID-19, gets very sick or dies from the condition, and who does not? Preliminary data from several early studies now point to yes.

Age-dependent effects in the transmission and control of COVID-19 epidemics
NG Davies, et al. Nature Medicine, June 16, 2020

We estimate that susceptibility to infection in individuals under 20 years of age is approximately half that of adults aged over 20 years, and that clinical symptoms manifest in 21% of infections in 10- to 19-year-olds, rising to 69% of infections in people aged over 70 years. Interventions aimed at children might have a relatively small impact on reducing transmission.

Disease and healthcare burden of COVID-19 in the United States
IF Miller et al, Nature Medicine, June 16, 2020

Impact of Host Genomics on COVID-19: What We Know and Don’t Know
CDC Webinar, July 23, 2020 Brand

Dr. Priya Duggal will discuss what we know and don’t know about the role of host genomics in COVID-19, as well as ongoing initiatives and studies that are seeking to assess the role of host genomics in COVID-19. She will also discuss the potential public health impact of host genomics in COVID-19 and the importance of sound epidemiological study designs.

Coronavirus breakthrough: dexamethasone is first drug shown to save lives
H Ledford, Nature News, June 16, 2020

In a large trial, a cheap and widely available steroid cut deaths by one-third among patients critically ill with COVID-19.

How deadly is the coronavirus? Scientists are close to an answer
S Malapaty, Nature News, June 16, 2020

One of the most crucial questions about an emerging infectious disease such as the new coronavirus is how deadly it is. After months of collecting data, scientists are getting closer to an answer.

Frequency of genomic secondary findings among 21,915 eMERGE network participants
Emerge Working Group, Genetics in Medicine, June 17, 2020

The study found 2.54% have variants from 59 genes the American College of Medical Genetics and Genomics recommends for return. Variants associated with cancer susceptibility were most frequent (1.38%), followed by cardiovascular diseases (0.87%), and lipid disorders (0.50%).


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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