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Hot Topics of the Day|PHGKB
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05/05/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

The Implementation Chasm Hindering Genome-informed Health Care.
Johnson Kevin B et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2020 Mar 48(1) 119-125

Challenges in returning results in a genomic medicine implementation study: the Return of Actionable Variants Empirical (RAVE) study
DC Kochan et al, NPJ Genomic Medicine, May 4, 2020

Challenges in returning actionable results were encountered in a significant proportion (38%) of the cohort and were related to reports revised based on clinical presentation (n?=?3); reports requiring corrections (n?=?2); mosaicism requiring alternative DNA samples for confirmation (n?=?3); and variant re-interpretation due to updated informatics pipelines (n?=?6)

Artificial intelligence vs COVID-19: limitations, constraints and pitfalls.
Naudé Wim et al. AI & society 2020 Apr 1-5

Should schools reopen? Kids’ role in pandemic still a mystery
G Vogel et al, Science, May 4, 2020

With Crispr, a Possible Quick Test for the Coronavirus: A pioneer of the gene-editing technology has devised a diagnostic test for the infection that could be as simple as a pregnancy test.
C Zimmer, NY Times, May 5, 2020

The Prime Cellular Targets for the Novel Coronavirus
NIH Director's Blog, May 5, 2020 Brand

A new study suggests that SARS-CoV-2 and potentially other coronaviruses that rely on ACE2 may take advantage of the immune system’s natural defenses. When the body responds to the infection by producing more interferon, that in turn results in production of more ACE2, enhancing the ability of the virus to attach more readily to lung cells.

A digital embrace to blunt the curve of COVID19 pandemic
LH Schwamm et al, NPJ Digital Medicine, May 4, 2020

Digital health, virtual care, telehealth, and telemedicine are all terms often used interchangeably to refer to the practice of care delivered from a distance. In this perspective, we offer implementation guidance relevant to the use of virtual care tools to meet the challenges of the COVID19 pandemic.

How Can Evidence Synthesis be Conducted at the Speed of a Pandemic?
CG ALlen et al, CDC Blog, May 2020 Brand

The speed at which new information is now available about COVID-19 is far outpacing our ability to synthesize the cumulative evidence in a timely fashion. Quality evidence synthesis is more important than ever. To save the most lives, we need the best available science in the global fight against COVID-19.

Chatbots in the fight against the COVID-19 pandemic
AS Miner, NPJ Digital Medicine, May 4, 2020


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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