Last data update: Jun 17, 2024. (Total: 47034 publications since 2009)
Records 1-10 (of 10 Records) |
Query Trace: Ingersoll R [original query] |
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Evaluating the implementation of family-centered substance use treatment for pregnant and postpartum people: A mixed-methods study
Coe JL , Morgan MH , Rehberg K , Kranzler EC , Ingersoll R , Namrow N , Huber-Krum S . J Subst Use Addict Treat 2024 209409 INTRODUCTION: Family-centered substance use treatment (FCSUT) approaches for pregnant and postpartum people have the potential to prevent intergenerational transmission of adverse childhood experiences (ACEs). Guided by two theoretical frameworks drawn from implementation science (the Consolidated Framework for Implementation Research [CFIR] and the Reach, Effectiveness, Adoption, Implementation and Maintenance [RE-AIM] framework), this study used a mixed methods approach to answer: (1) What is the extent to which FCSUT approaches are offered for pregnant and postpartum people seeking substance use disorder (SUD) treatment? and (2) How are FCSUT approaches for pregnant and postpartum people implemented? METHODS: This study utilized a sequential mixed methods design that began with quantitative data collection followed by qualitative data collection. The quantitative component consisted of service provision surveys of facilities that provided FCSUT to pregnant and postpartum people (n = 118). The qualitative component consisted of semi-structured in-depth interviews with administrators and providers working at FCSUT facilities (n = 26) and pregnant and postpartum people who were currently receiving or had previously received services in the last two years from FCSUT facilities (n = 27). The qualitative findings were used to deepen understanding of the quantitative findings. RESULTS: Findings from the quantitative survey of treatment facilities' FCSUT provision revealed that while most facilities offered services related to substance use treatment, behavioral health, and parenting skills development or parent training, a smaller proportion offered services related to prenatal and postpartum health, sexual and reproductive health, and family-related services. Qualitative in-depth interviews with program administrators and providers and pregnant and postpartum people who had participated in FCSUT programs revealed major themes around expanding reach of facilities by maintaining participants' familial connections, resources for implementation and maintenance of FCSUT, the importance of program adaptation, and gaps in service delivery. CONCLUSIONS: Results indicated there is a wide range of FCSUT services offered at treatment facilities across the United States. Furthermore, while many pregnant and postpartum people expressed positive experiences with FCSUT, there are some areas that should be considered for future progress to be made. |
Unrecognized introductions of SARS-CoV-2 into the state of Georgia shaped the early epidemic (preprint)
Babiker A , Martin MA , Marvil C , Bellman S , Petit Iii RA , Bradley HL , Stittleburg VD , Ingersoll J , Kraft CS , Read TD , Waggoner JJ , Koelle K , Piantadosi A . medRxiv 2021 2021.09.19.21262615 In early 2020, as SARS-CoV-2 diagnostic and surveillance responses ramped up, attention focused primarily on returning international travelers. Here, we build on existing studies characterizing early patterns of SARS-CoV-2 spread within the U.S. by analyzing detailed clinical, molecular, and viral genomic data from the state of Georgia through March 2020. We find evidence for multiple early introductions into Georgia, despite relatively sparse sampling. Most sampled sequences likely stemmed from a single introduction from Asia at least two weeks prior to the state’s first detected infection. Our analysis of sequences from domestic travelers demonstrates widespread circulation of closely-related viruses in multiple U.S. states by the end of March 2020. Our findings indicate that the early attention directed towards identifying SARS-CoV-2 in returning international travelers may have led to a failure to recognize locally circulating infections for several weeks, and points towards a critical need for rapid and broadly-targeted surveillance efforts in the future.Competing Interest StatementThe authors have declared no competing interest.Funding StatementThis study was supported by the CDC contract 75D30121C10084 under BAA ERR 20-15-2997 the Pediatric Research Alliance Center for Childhood Infections and Vaccines and Childrens Healthcare of Atlanta and the Emory WHSC COVID-19 Urgent Research Engagement (CURE) Center made possible by generous philanthropic support from the O. Wayne Rollins Foundation and the William Randolph Hearst Foundation. AP is supported by NIH K08 AI139348. The Yerkes NHP Genomics Core is supported in part by NIH P51 OD011132 and sequence data was acquired on an Illumina NovaSeq6000 funded by NIH S10 OD 026799. Sample collection was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR002378. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Author DeclarationsI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.YesThe details of the IRB/oversight body that provided approval or exemption for the research described are given below:This study was approved by the Emory University institutional review boardAll necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.YesI understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).YesI have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.YesPublicly-available SARS-CoV-2 sequences from Georgia were generously contributed by Mayo Clinic Laboratories, Quest Diagnostics, and the U.S. Air Force School of Aerospace Medicine. We gratefully acknowledge the authors from the originating laboratories responsible for obtaining the specimens, as well as the submitting laboratories where the genome data were generated and shared via GISAID, on which this research is based (Supplementary Table 10). All Submitters of data may be contacted directly via www.gisaid.org.All the data will be publicly released upon publication. |
Association of Secretor Status and Recent Norovirus Infection With Gut Microbiome Diversity Metrics in a Veterans Affairs Population.
Johnson JA , Read TD , Petit RA3rd , Marconi VC , Meagley KL , Rodriguez-Barradas MC , Beenhouwer DO , Brown ST , Holodniy M , Lucero-Obusan CA , Schirmer P , Ingersoll JM , Kraft CS , Neill FH , Atmar RL , Kambhampati AK , Cates JE , Mirza SA , Hall AJ , Cardemil CV , Lopman BA . Open Forum Infect Dis 2022 9 (5) ofac125 ![]() ![]() Norovirus infection causing acute gastroenteritis could lead to adverse effects on the gut microbiome. We assessed the association of microbiome diversity with norovirus infection and secretor status in patients from Veterans Affairs medical centers. Alpha diversity metrics were lower among patients with acute gastroenteritis but were similar for other comparisons. |
Unrecognized introductions of SARS-CoV-2 into the US state of Georgia shaped the early epidemic.
Babiker A , Martin MA , Marvil C , Bellman S , Petit Iii RA , Bradley HL , Stittleburg VD , Ingersoll J , Kraft CS , Li Y , Zhang J , Paden CR , Read TD , Waggoner JJ , Koelle K , Piantadosi A . Virus Evol 2022 8 (1) veac011 ![]() In early 2020, as diagnostic and surveillance responses for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ramped up, attention focused primarily on returning international travelers. Here, we build on existing studies characterizing early patterns of SARS-CoV-2 spread within the USA by analyzing detailed clinical, molecular, and viral genomic data from the state of Georgia through March 2020. We find evidence for multiple early introductions into Georgia, despite relatively sparse sampling. Most sampled sequences likely stemmed from a single or small number of introductions from Asia three weeks prior to the state's first detected infection. Our analysis of sequences from domestic travelers demonstrates widespread circulation of closely related viruses in multiple US states by the end of March 2020. Our findings indicate that the exclusive focus on identifying SARS-CoV-2 in returning international travelers early in the pandemic may have led to a failure to recognize locally circulating infections for several weeks and point toward a critical need for implementing rapid, broadly targeted surveillance efforts for future pandemics. |
Sampling for SARS-CoV-2 Aerosols in Hospital Patient Rooms.
Lane MA , Walawender M , Webster AS , Brownsword EA , Ingersoll JM , Miller C , Waggoner J , Uyeki TM , Lindsley WG , Kraft CS . Viruses 2021 13 (12) ![]() ![]() Evidence varies as to how far aerosols spread from individuals infected with SARS-CoV-2 in hospital rooms. We investigated the presence of aerosols containing SARS-CoV-2 inside of dedicated COVID-19 patient rooms. Three National Institute for Occupational Safety and Health BC 251 two-stage cyclone samplers were set up in each patient room for a six-hour sampling period. Samplers were place on tripods, which each held two samplers at various heights above the floor. Extracted samples underwent reverse transcription polymerase chain reaction for selected gene regions of the SARS-CoV-2 virus nucleocapsid. Patient medical data were compared between participants in rooms where virus-containing aerosols were detected and those where they were not. Of 576 aerosols samples collected from 19 different rooms across 32 participants, 3% (19) were positive for SARS-CoV-2, the majority from near the head and foot of the bed. Seven of the positive samples were collected inside a single patient room. No significant differences in participant clinical characteristics were found between patients in rooms with positive and negative aerosol samples. SARS-CoV-2 viral aerosols were detected from the patient rooms of nine participants (28%). These findings provide reassurance that personal protective equipment that was recommended for this virus is appropriate given its spread in hospital rooms. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Bioaerosol sampling for SARS-CoV-2 in a referral center with critically ill COVID-19 patients March-May 2020.
Lane MA , Brownsword EA , Babiker A , Ingersoll JM , Waggoner J , Ayers M , Klopman M , Uyeki TM , Lindsley WG , Kraft CS . Clin Infect Dis 2021 73 (7) e1790-e1794 ![]() BACKGROUND: Previous research has shown that rooms of patients with COVID-19 present the potential for healthcare-associated transmission through aerosols containing SARS-CoV-2. However, data on the presence of these aerosols outside of patient rooms are limited. We investigated whether virus-containing aerosols were present in nursing stations and patient room hallways in a referral center with critically ill COVID-19 patients. METHODS: Eight National Institute for Occupational Safety and Health BC 251 two-stage cyclone samplers were set up throughout six units, including nursing stations and visitor corridors in intensive care units and general medical units, for six hours each sampling period. Samplers were placed on tripods which held two samplers positioned 102 cm and 152 cm above the floor. Units were sampled for three days. Extracted samples underwent reverse transcription polymerase chain reaction for selected gene regions of the SARS-CoV-2 virus nucleocapsid and the housekeeping gene human RNase P as an internal control. RESULTS: The units sampled varied in the number of laboratory-confirmed COVID-19 patients present on the days of sampling. Some of the units included patient rooms under negative pressure, while most were maintained at a neutral pressure. Of 528 aerosol samples collected, none were positive for SARS-CoV-2 RNA by the estimated limit of detection of 8 viral copies/m 3 of air. CONCLUSION: Aerosolized SARS-CoV-2 outside of patient rooms was undetectable. While healthcare personnel should avoid unmasked close contact with each other, these findings may provide reassurance for the use of alternatives to tight-fitting respirators in areas outside of patient rooms during the current pandemic. |
Bioaerosol sampling of a ventilated patient with COVID-19.
Lane MA , Brownsword EA , Morgan JS , Babiker A , Vanairsdale SA , Lyon GM , Mehta AK , Ingersoll JM , Lindsley WG , Kraft CS . Am J Infect Control 2020 48 (12) 1540-1542 Bioaerosol samples were collected in an airborne infection isolation room, bathroom and anteroom of a ventilated patient with coronavirus disease 2019. Twenty-eight samples were negative for SARS-CoV-2 nucleic acid, possibly due to the patient being on a closed-circuit ventilator or the efficiency of the air exchanges in the room. |
Performance evaluation of the Aptima HIV-1 RNA Quant assay on the Panther system using the standard and dilution protocols
Rossetti R , Smith T , Luo W , Taussig J , Valentine-Graves M , Sullivan P , Ingersoll JM , Kraft CS , Ethridge S , Wesolowski L , Delaney KP , Owen SM , Johnson JA , Masciotra S . J Clin Virol 2020 129 104479 BACKGROUND: Currently, FDA-approved HIV-1 viral load (VL) assays use venipuncture-derived plasma. The Hologic Panther system uses 0.7mL total volume for the Aptima HIV-1 Quant Assay standard (APT-Quant-std) and dilution (APT-Quant-dil) protocols. However, smaller plasma volumes from fingerstick whole blood (FSB) collected in EDTA-microtainer tubes (MCT) could provide an easier sample collection method for HIV-1 VL testing. OBJECTIVES: To evaluate the performance of the APT-Quant-std compared to the Roche CAP/CTM and Abbott m2000RT VL assays and an alternative APTQuant 1:7 dilution protocol, the latter using 100muL of MCT-derived plasma from FSB. STUDY DESIGN: Linearity was determined using commercial HIV-1 RNA plasma controls. Dilutions ranging 1.56-2.95 log10 copies/mL were prepared to determine the APT-Quant-dil Limit of Quantitation (LOQ) using Probit analysis. Specificity of APT-Quant-std was calculated using 326 HIVnegative samples. To evaluate agreement, 329 plasma specimens were tested with APT-Quant-std, CAP/CTM, and m2000RT. Forty-seven matched venipuncture and MCT-derived plasma specimens were tested with APT-Quant-std and APT-Quant-dil. RESULTS: Among the RNA controls, specificity was 99.69 % for APT-Quant-std. The R2 values were 0.988 (APT-Quant-std/CAP/CTM), 0.980 (APT-Quant-std/ m2000RT), and 0.997 (APT-Quant-std/APT-Quant-dil). The APT-Quant-dil LOQ was estimated at 2.7 log10 copies/mL (500 copies/mL) (95 %CI 2.62-2.87). At 2.3 log10 copies/mL (200 copies/mL), the overall agreement was 91.0 % for APT-Quant-std/CAP/CTM, 85.7 % for APT-Quant-std/m2000RT, and 82.9 % for APT-Quant-std/APT-Quant-dil. Quantified APT-Quant-std results were on average 0.2 log10 copies/mL higher than CAP/CTM and m2000RT and 0.14 log10 copies/mL higher than APT-Quant-dil. CONCLUSION: APT-Quant showed similar performance compared to the CAP/CTM and m2000RT assays and remains sensitive and accurate using the dilution protocol. |
How to buy safer, quieter tools: a process management approach to reducing noise and hand-arm vibration while improving productivity and quality
Zechmann E , Geiger M , Beamer B . Synergist 2018 29 (1) 26-30 Powered hand tools have become essential to a range of industrial operations since Samuel Ingersoll invented the pneumatic drill in 1871. However, progress often comes with risk. Potential hazards associated with hand-held powered tool use include noise, hand-arm vibration, and a range of ergonomic stresses and physical safety hazards. Acute physical injuries from failure or misuse of the control or trigger mechanism are a particular concern, especially for products such as nail guns. At the same time, many companies using power tools fail to employ a process management approach to selection, procurement, and maintenance, or to educate users of these tools. This often results in unnecessary exposures to noise, vibration, and other physical hazards, as well as impaired productivity and quality. Because few purchasing groups are trained in safety, they are unlikely to consider the hazards and lifecycle costs associated with operating power tools. Efforts to promote purchasing of tools with lower lifecycle costs have failed due to a lack of regulatory criteria, misguided pressure to purchase the tools with the lowest initial costs, and poor understanding of hazardous exposures. Concurrently, safety and health professionals have often failed to influence the purchasing process. A purchasing and process management standard was needed to correct these failings and to stimulate the market conditions for manufacturing and purchasing of power tools that optimize productivity and minimize lifecycle costs. This article outlines a process management approach to the purchase of powered hand-held tools promoted in SAE International Standard AS6228, "Safety Requirements for Procurement, Maintenance and Use of Hand-held Powered Tools." |
Engaging students in physical education: Key challenges and opportunities for physical educators in urban settings
Sliwa S , Nihiser A , Lee S , McCaughtry N , Culp B , Michael S . J Phys Educ Recreat Dance 2017 88 (8) 43-48 A well-designed physical education (PE) program is inclusive, active, enjoyable and supportive (SHAPE America – Society of Health and Physical Educators, 2015). Irrespective of location, programs are affected by a host of issues in the midst of various school and community climates. Trends toward urbanization in the United States (U.S. Census Bureau, 2012) and worldwide (World Health Organization, 2016) suggest that more and more PE teachers will be working in urban settings. | In October 2009, JOPERD published a special symposium about “Engaging Urban Youths in Physical Education and Physical Activity” (Murgia & McCullick, 2009). Seven years later, many of those considerations remain relevant, such as large class sizes (Dyson, Coviello, DiCesare, & Dyson, 2009; Schmidlein, Vickers, & Chepyator-Thomson, 2014) and limited access to equipment (Schmidlein et al., 2014), a dedicated gymnasium (Fernandes & Sturm, 2010), or outdoor space (Dyson et al., 2009; Hobin et al., 2013). These structural challenges matter. For example, some data suggest that larger class sizes and indoor lessons are associated with students spending significantly less time in moderate-to-vigorous physical activity and with teachers spending more time on classroom management (Skala et al., 2012). In addition, high rates of teacher turnover (Ingersoll, Merrill, & Stuckey, 2014), difficulties communicating with English language learners (ELLs; Kena et al., 2016), and low self-efficacy (Fletcher, Mandigo, & Kosnik, 2013) affect teachers’ ability to engage students in PE in urban settings. |
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