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COVID-10 GPH

Last data update: Aug 15, 2025. (Total: 49733 publications since 2009)
(Author names in bold with hyperlink are CDC authors)
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Query Trace: Hercules YR [original query]
Molecular detection and isolation of clade Ib monkeypox virus, Canada, November 2024
Chan M , Audet J , Prévost J , Soriano K , Doan K , Garnett L , Deschambault Y , Medina S , Stefopulos M , Paul J , Lee S , Kurbis C , Fatoye B , Duggan AT , Eaton K , Chato C , Hole D , Papineau A , Dust K , Van Caeseele P , Hercules YR , Gearhart S , Embil J , Walkty A , Romaniuk D , Safronetz D , Strong JE .
Euro Surveill 2025 30 (25) type type

In November 2024, a case of clade Ib mpox was confirmed in Canada. Here, we describe the events that led to laboratory confirmation of clade Ib monkeypox virus (MPXV) and the public health response. Genomic analysis of the Canadian clade Ib MPXV revealed a number of APOBEC3-related mutations suggesting sustained human-to-human transmission. These findings expand the number of countries with travel-related clade Ib mpox and highlights the continued need for mpox monitoring of potential human adaptations or new transmission patterns.
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