Advanced Molecular Detection Clips Content (Published on 03/18/2021)
NEWS
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COVID-19 Testing Supply Shortages Disrupt 45% of Laboratories, CAP Survey Shows
BusinessWire, Mar 22, 2021. -
Coronavirus sequence trove sparks frustration
Wadman M. Science, Mar 12, 2021. -
Virus Variants Likely Evolved Inside People With Weak Immune Systems
Mandavilli A. New York Times, Mar 15, 2021. -
Tracking the emergence of new SARS-CoV-2 variants in South Africa.
Happi Anise N et al. Nature medicine 2021 3 (3) 372-373 -
Regular booster vaccines are the future in battle with COVID-19 virus, top genome expert says
Faulconbridge G. Reuters, Mar 15, 2021. -
Coronavirus strains from California and the U.K. in battle for U.S. dominance
Healy M. Los Angeles Times, Mar 17, 2021. -
FDA authorizes first T cell-based test to detect prior SARS-CoV-2
Medical Xpress, Mar 10, 2021. -
Coronavirus Reinfections Are Rare, Danish Researchers Report
Mandavilli A. New York Times, Mar 17, 2021. -
Innovators target vaccines for variants and shortages in global South
Sheridan C. Nature, Mar 17, 2021. -
New Ebola outbreak likely sparked by a person infected 5 years ago
Kupferschmidt K. Science, Mar 12, 2021. -
Achilles heel spotted for promising HIV-prevention drug
Maxmen A. Nature, Mar 9, 2021. -
Scientists Find New Invasive Mosquito Species In Florida
Allen G. NPR, Mar 16, 2021.
CONCEPTS / COMMENTS
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Machine learning and applications in microbiology.
Goodswen Stephen J et al. FEMS microbiology reviews 2021 3
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Regional Consortia : A Framework for Public Health Laboratory Collaboration and Service Sharing.
Ned-Sykes Renée M et al. Public health reports (Washington, D.C. : 1974) 2021 3 333549211002774
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Preparing for the next pandemic.
et al. Nature medicine 2021 3 (3) 357 -
Promoting diagnostics as a global good.
Boehme Catharina et al. Nature medicine 2021 3 (3) 367-368 -
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases.
Meganck Rita M et al. Nature medicine 2021 3 (3) 401-410 -
How Cooperative Engagement Programs Strengthen Sequencing Capabilities for Biosurveillance and Outbreak Response
Bartlow AW, et al. Front Public Health. 2021 Mar 1;9:648424. -
The first 12 months of COVID-19: a timeline of immunological insights.
Carvalho Thiago et al. Nature reviews. Immunology 2021 3
METHODS / TOOLS
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Identification of Shiga Toxin-Producing Escherichia coli Outbreaks Using Whole Genome Sequencing.
Bletz Stefan et al. Methods in molecular biology (Clifton, N.J.) 2021 3 87-97
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The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR.
Song Shuhui et al. Genomics, proteomics & bioinformatics 2021 3 -
Coronavirus GenBrowser for monitoring the transmission and evolution of SARS-CoV-2
Yu D, et al. medRxiv, Mar 11, 2021. -
VERSO: A comprehensive framework for the inference of robust phylogenies and the quantification of intra-host genomic diversity of viral samples.
Ramazzotti Daniele et al. Patterns (New York, N.Y.) 2021 3 (3) 100212
EVOLUTION / ECOLOGY / POPULATIONS
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Genomic Epidemiology of CC30 Methicillin-Resistant Staphylococcus aureus Strains from Argentina Reveals Four Major Clades with Distinctive Genetic Features.
Di Gregorio Sabrina et al. mSphere 2021 3 (2) -
Draft Genome Sequences of 62 Staphylococcus aureus Isolates Associated with Four Foodborne Outbreaks in the United States.
Hait Jennifer et al. Microbiology resource announcements 2021 3 (10) -
Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen.
MacLean Oscar A et al. PLoS biology 2021 3 (3) e3001115 -
Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein.
Tegally Houriiyah et al. Nature 2021 3 -
Surveillance of SARS-CoV-2 in Zimbabwe shows dominance of variants of concern
Mashe T, et al. Lancet Microbe, Mar 10, 2021. -
Recombinant SARS-CoV-2 genomes are currently circulating at low levels
VanInsberghe D, et al. bioRxiv, Mar 15, 2021. -
Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunity.
Truong Thao T et al. medRxiv : the preprint server for health sciences 2021 3 -
Avian influenza overview December 2020 - February 2021.
et al. EFSA journal. European Food Safety Authority 2021 3 (3) e06497 -
Persistence of the historical lineage I of West Africa against the ongoing spread of the Asian lineage of peste des petits ruminants virus.
Tounkara Kadidia et al. Transboundary and emerging diseases 2021 3 -
Discovery of novel herpes simplexviruses in wild gorillas, bonobos, and chimpanzees supports zoonotic origin of HSV-2.
Wertheim Joel O et al. Molecular biology and evolution 2021 3
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Distinctive Mobile Genetic Elements Observed in the Clonal Expansion of Carbapenem-Resistant Klebsiella pneumoniae in India
Shankar Chaitra et al. Microbial drug resistance (Larchmont, N.Y.) 2021 3 -
Genomic Analysis of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Strains from Different Clonal Lineages in South Korea
Park Chulmin et al. Microbial drug resistance (Larchmont, N.Y.) 2021 3 -
The Distinctive Evolution of orfX Clostridium parabotulinum Strains and Their Botulinum Neurotoxin Type A and F Gene Clusters Is Influenced by Environmental Factors and Gene Interactions via Mobile Genetic Elements
Smith Theresa J et al. Frontiers in microbiology 2021 3 566908 -
The extent of carbapenemase-encoding genes in public genome sequences
Janse I, et al. PeerJ. 2021 Mar 9;9:e11000. -
SARS-CoV-2 genomic surveillance identifies naturally occurring truncations of ORF7a that limit immune suppression
Nemudryi A, et al. medRxiv, Mar 10, 2021. -
Impact of pre-existing drug resistance on risk of virological failure in South Africa.
Li Jonathan Z et al. The Journal of antimicrobial chemotherapy 2021 3
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Isavuconazole Nonwildtype Aspergillus fumigatus Isolates from a Global Surveillance Study Display Alterations in Multiple Genes Involved in the Ergosterol Biosynthesis Pathway Not Previously Associated with Resistance to Other Azoles.
Castanheira Mariana et al. Mycoses 2021 3
DETECTION / DIAGNOSIS
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Phylogenetic structure of Shiga toxin-producing Escherichia coli O157:H7 from sub-lineage to SNPs
Dallman Timothy J et al. Microbial genomics 2021 3 -
A Novel Molecular Method for Simultaneous Identification of Vibrio parahaemolyticus 57 K-Serogroups Using Probe Melting Curve Analysis
Lu Linying et al. Frontiers in cellular and infection microbiology 2021 3 594808
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Molecular diagnostic assays for the detection of common bacterial meningitis pathogens: A narrative review.
Diallo Kanny et al. EBioMedicine 2021 3 103274 -
Analysis of recombinant proteins for Q fever diagnostics.
Miller Halie K et al. Scientific reports 2020 12 (1) 20934
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Phenotypic and genomic profiling of Staphylococcus argenteus in Canada and the United States and recommendations for clinical result reporting
Eshaghi A, et al. J Clin Microbiol. 2021 Mar 17;JCM.02470-20.
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Towards a sensitive and accurate interpretation of molecular testing for SARS-CoV-2: a rapid review of 264 studies.
Stanoeva Kamelia R et al. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2021 3 (10)
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Surveillance of SARS-CoV-2 in Zimbabwe shows dominance of variants of concern.
Mashe Tapfumanei et al. The Lancet. Microbe 2021 3 -
The presence of SARS-CoV-2 RNA in human sewage in Santa Catarina, Brazil, November 2019.
Fongaro Gislaine et al. The Science of the total environment 2021 3 146198 -
SalivaDirect: A simplified and flexible platform to enhance SARS-CoV-2 testing capacity.
Vogels Chantal B F et al. Med (New York, N.Y.) 2021 2 (3) 263-280.e6 -
Capturing noroviruses circulating in the population: sewage surveillance in Guangdong, China (2013-2018).
Lu Jing et al. Water research 2021 3 116990 -
Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine
Zeller MA, et al. mSphere. 2021 Mar 17;6(2):e00920-20. -
Rapid parasite detection utilizing a DNA dipstick.
Aula Oyime Poise et al. Experimental parasitology 2021 3 108098
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Tracking the Origin of Austrian Human Brucellosis Cases Using Whole Genome Sequencing.
Schaeffer Justine et al. Frontiers in medicine 2021 3 635547 -
Molecular Epidemiology and Clone Transmission of Carbapenem-Resistant Acinetobacter baumannii in ICU Rooms
Zhang X, et al. Front Cell Infect Microbiol. 2021 Feb 26;11:633817. -
Travel from the United Kingdom to the United States by a Symptomatic Patient Infected with the SARS-CoV-2 B.1.1.7 Variant - Texas, January 2021.
Ojelade Moriam et al. MMWR. Morbidity and mortality weekly report 2021 3 (10) 348-349 -
Genomic and healthcare dynamics of nosocomial SARS-CoV-2 transmission.
Ellingford Jamie M et al. eLife 2021 3 -
Genomic investigation of the coronavirus disease-2019 outbreak in the Republic of Korea.
Kim Jeong-Min et al. Scientific reports 2021 3 (1) 6009
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An integrated analysis of contact tracing and genomics to assess the efficacy of travel restrictions on SARS-CoV-2 introduction and transmission in England from June to September, 2020
Aggarwal D, et al. medRxiv, Mar 17, 2021.
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Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 during Border Quarantine and Air Travel, New Zealand (Aotearoa)
Eichler N, et al. Emerg Infect Dis. 2021 May [Mar 18, 2021]. https://doi.org/10.3201/eid2705.210514
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Subgrouping and Analysis of Relationships between Classical Swine Fever Virus Identified During the 2018-2020 Epidemic in Japan by a Novel Approach Using Shared Genomic Variants.
Yamamoto Takehisa et al. Transboundary and emerging diseases 2021 3
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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Facile accelerated specific therapeutic (FAST) platform develops antisense therapies to counter multidrug-resistant bacteria.
Eller Kristen A et al. Communications biology 2021 3 (1) 331 -
Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant.
Madhi Shabir A et al. The New England journal of medicine 2021 3 -
Recent advances in human norovirus research and implications for candidate vaccines.
Cates Jordan E et al. Expert review of vaccines 2020 6 (6) 539-548
HOST-MICROBE INTERACTIONS
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Mapping the human genetic architecture of COVID-19 by worldwide meta-analysis
The COVID-19 Host Genetics Initiative, medRxiv, Mar 12, 2021. -
The intersection of genetics and COVID-19 in 2021: preview of the 2021 Rodney Howell Symposium
Rasmussen S, et al. Genet Med, Mar 12, 2021. -
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.
Butler Daniel et al. Nature communications 2021 3 (1) 1660 -
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication.
Zhang Yuchen et al. Nature communications 2021 3 (1) 1676 -
Nasopharyngeal Microbiome Signature in COVID-19 Positive Patients: Can We Definitively Get a Role to
Nardelli Carmela et al. Frontiers in cellular and infection microbiology 2021 3 625581 -
16S rRNA gene sequencing of rectal swab in patients affected by COVID-19.
Mazzarelli Antonio et al. PloS one 2021 2 (2) e0247041 -
Viral and host heterogeneity and their effects on the viral life cycle.
Jones Jennifer E et al. Nature reviews. Microbiology 2020 10 -
Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity.
Fadista João et al. EBioMedicine 2021 3 103277 -
Strain-Resolved Dynamics of the Lung Microbiome in Patients with Cystic Fibrosis.
Dmitrijeva Marija et al. mBio 2021 3 (2)
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice. Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Oct 1, 2023
- Page last updated:Nov 16, 2023
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