Advanced Molecular Detection Clips Content (Published on 02/11/2021)
NEWS
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Scientists call for fully open sharing of coronavirus genome data
Van Noorden R. Nature, Feb 3, 2021. -
U.S. rushes to fill void in viral sequencing as worrisome coronavirus variants spread
Wadman M. Science, Feb 9, 2021. -
The Coronavirus Is a Master of Mixing Its Genome, Worrying Scientists
Khamsi R. New York Times, Feb 8, 2021. -
NYC to Fund Coronavirus Surveillance Sequencing as Congress Proposes $2B for Nationwide Program
Han AP. GenomeWeb, Feb 4, 2021. -
China probe: SARS-CoV-2 jump from go-between host most likely scenario
Schnirring L. CIDRAP, Feb 9, 2021. -
COVID may have taken 'convoluted path' to Wuhan, WHO team leader says
Horwitz J, Stanway D. Reuters, Feb 8, 2021. -
Understanding variants of SARS-CoV-2.
Burki Talha et al. Lancet (London, England) 2021 02 (10273) 462 -
Variants mean the coronavirus is here to stay -- but perhaps as a lesser threat
Johnson CY. Washington Post, Feb 9, 2021. -
Covid-19 cases are falling in the U.S. It could be a calm before a variant-driven storm
Joseph A. STAT, Feb 10, 2021. -
Extraordinary Patient Offers Surprising Clues To Origins Of Coronavirus Variants
Doucleff M. NPR, Feb 5, 2021. -
How a sluggish vaccination program could delay a return to normal and invite vaccine-resistant variants to emerge
Stevens H, et al. Washington Post, Feb 9, 2021. -
Could mixing COVID vaccines boost immune response?
Ledford H. Nature, Feb 4, 2021. -
Could a Single Vaccine Work Against All Coronaviruses?
Zimmer C. New York Times, Feb 9, 2021. -
The FDA wants to make it quicker for vaccine developers to upgrade their COVID-19 shots to respond to troubling virus variants
Dunn A. Business Insider, Feb 4, 2021. -
Why the U.S. Is Underestimating Covid Reinfection
Aleccia J. Kaiser Health News, Feb 8, 2021. -
CRISPR-Based COVID-19 Smartphone Test in Development
Abassi J. JAMA, Feb 9, 2021.
EVENTS / TRAINING / WEB RESOURCES
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Coronavirus Variants and Mutations
Corum J, Zimmer C. New York Times, Feb 8, 2021. -
Conducting Research in the COVID-19 Pandemic: Ethics in an Emergency
(Zoom conference) Univ of Minnesota, Mar 3, 2021.
CONCEPTS / COMMENTS
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Genomic sequencing in pandemics.
The Lancet et al. Lancet (London, England) 2021 Feb (10273) 445 -
An action plan for pan-European defence against new SARS-CoV-2 variants.
Priesemann Viola et al. Lancet (London, England) 2021 02 (10273) 469-470 -
Superspreading genomes.
Alizon Samuel et al. Science (New York, N.Y.) 2021 02 (6529) 574-575 -
Variant-proof vaccines - invest now for the next pandemic
Burton DR, Topol E. Nature, Feb 8, 2021.
METHODS / TOOLS
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GalaxyTrakr: a distributed analysis tool for public health whole genome sequence data accessible to non-bioinformaticians
Gangiredla J, et al. BMC Genomics. 2021 Feb 10;22(1):114. -
CovMT: an interactive SARS-CoV-2 mutation tracker, with a focus on critical variants
Alam I, et al. Lancet Infect Dis, Feb 8, 2021. -
Early warning of COVID-19 via wastewater-based epidemiology: potential and bottlenecks.
Zhu Yifan et al. The Science of the total environment 2021 Jan 145124
EVOLUTION / ECOLOGY / POPULATIONS
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Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history.
Coscolla Mireia et al. Microbial genomics 2021 Feb -
Genomic Diversity of Burkholderia pseudomallei in Ceara, Brazil.
Gee Jay E et al. mSphere 2021 02 (1)
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Phylogenetic and genetic characterization of Treponema pallidum strains from syphilis patients in Japan by whole-genome sequence analysis from global perspectives.
Nishiki Shingo et al. Scientific reports 2021 Feb (1) 3154
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Globally diverse Mycobacterium tuberculosis resistance acquisition: a retrospective geographical and temporal analysis of whole genome sequences
Ektefaie Y, et al. Lancet Microbe -
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates
Schrors B, et al. bioRxiv, Feb 4, 2021. -
SARS-CoV-2 Worldwide Replication Drives Rapid Rise and Selection of Mutations across the Viral Genome: A Time-Course Study Potential Challenge for Vaccines and Therapies
Weber S, et al. medRxiv, Feb 6, 2021. -
Mutational hotspots and conserved domains of SARS-CoV-2 genome in African population.
Omotoso Olabode E et al. Beni-Suef University journal of basic and applied sciences 2021 (1) 11 -
Genomic epidemiology identifies emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States
Washington NL, et al. medRxiv, Feb 7, 2021. -
The heterogeneous landscape and early evolution of pathogen-associated CpG dinucleotides in SARS-CoV-2.
Di Gioacchino Andrea et al. Molecular biology and evolution 2021 Feb -
Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup
Lau SK, et al. mSphere. 2021 Feb 10;6(1):e00819-20. -
Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia.
Wacharapluesadee Supaporn et al. Nature communications 2021 02 (1) 972 -
Detection of Nipah virus in Pteropus medius in 2019 outbreak from Ernakulam district, Kerala, India.
Sudeep A B et al. BMC infectious diseases 2021 Feb (1) 162 -
High Diversity of Human Non-Polio Enterovirus Serotypes Identified in Contaminated Water in Nigeria.
Majumdar Manasi et al. Viruses 2021 Feb (2)
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Prevalence and molecular characterizations of seven additional drug resistance among multidrug-resistant tuberculosis in China: a subsequent study of a national survey.
Wang Guirong et al. The Journal of infection 2021 Feb -
Low but Increasing Prevalence of Reduced Beta-lactam Susceptibility Among Invasive Group B Streptococcal Isolates, US Population-Based Surveillance, 1998-2018.
Miwako Kobayashi et al. Open Forum Infect Dis 2021 2 (2) ofaa634
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Disseminated Gonococcal Infection Complicated by Prosthetic Joint Infection: Case Report and Genomic and Phylogenetic Analysis.
Ogbebor Osakpolor et al. Open forum infectious diseases 2021 Feb (2) ofaa632 -
Epidemiological analysis of pneumococcal strains isolated at Yangon Children's Hospital in Myanmar via whole-genome sequencing-based methods.
Yamaguchi Masaya et al. Microbial genomics 2021 Feb -
Genetic Conservation of SARS-CoV-2 RNA Replication Complex in Globally Circulating Isolates and Recently Emerged Variants from Humans and Minks Suggests Minimal Pre-Existing Resistance to Remdesivir.
Martin Ross et al. Antiviral research 2021 Feb 105033 -
Increased SAR-CoV-2 shedding associated with reduced disease severity despite continually emerging genetic variants
Tang CY, et al. medRxiv, Feb 5, 2021. -
Genomic Signatures of SARS-CoV-2 Associated with Patient Mortality.
Dumonteil Eric et al. Viruses 2021 02 (2) -
Western Kenyan Anopheles gambiae showing intense permethrin resistance harbour distinct microbiota.
Omoke Diana et al. Malaria journal 2021 Feb (1) 77
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Insights into the evolution and dispersion of pyrethroid resistance among sylvatic Andean Triatoma infestans from Bolivia.
Marcet Paula L et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2021 Feb 104759
DETECTION / DIAGNOSIS
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Pulse-Controlled Amplification: A new powerful tool for on-site diagnostics under resource limited conditions
Muller K, et al. PLoS Negl Trop Dis, Jan 29, 2021. -
Infectious agents in biological samples from patients with Guillain-Barré syndrome in Peru, 2018-2019.
Pachas Paul et al. Revista peruana de medicina experimental y salud publica (4) 681-688 -
Microbial source tracking using metagenomics and other new technologies.
Raza Shahbaz et al. Journal of microbiology (Seoul, Korea) 2021 Feb -
Identification of closely related Listeria monocytogenes isolates with no apparent evidence for a common source or location: a retrospective WGS analysis.
Orsi Renato Hohl et al. Journal of food protection 2021 Feb -
Using molecular testing and whole-genome sequencing for tuberculosis diagnosis in a low-burden setting: a cost-effectiveness analysis using transmission-dynamic modelling.
Mugwagwa Tendai et al. Thorax 2021 Feb
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Rapid Impact Analysis of B 1.1.7 Variant on the Spread of SARS-CoV-2 in North Carolina
DeWitt M. medRxiv, Feb 9, 2021. -
Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection.
Teo Alvin Kuo Jing et al. Scientific reports 2021 02 (1) 3134 -
Rapid electrochemical detection of coronavirus SARS-CoV-2.
Chaibun Thanyarat et al. Nature communications 2021 02 (1) 802 -
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood.
Ng Dianna L et al. Science advances 2021 02 (6) -
Rapid detection of SARS-CoV-2 by pulse-controlled amplification (PCA).
Zwirglmaier Katrin et al. Journal of virological methods 2021 Jan 114083 -
Multi-annual performance evaluation of laboratories in post-mortem diagnosis of animal rabies: Which techniques lead to the most reliable results in practice?
Robardet Emmanuelle et al. PLoS neglected tropical diseases 2021 Feb (2) e0009111
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Persistence of Ebola virus in semen among Ebola virus disease survivors in Sierra Leone: A cohort study of frequency, duration, and risk factors.
Thorson A E et al. PLoS medicine 2021 Feb (2) e1003273
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Pseudomonas aeruginosa infection in augmented care: the molecular ecology and transmission dynamics in four large UK hospitals.
Halstead Fenella D et al. The Journal of hospital infection 2021 Feb -
Outbreak of Central American born Shigella sonnei in two youth camps in Belgium in the summer of 2019
Van den Bossche A et al, Eur J Clin Microbiol Infect Dis 2021 Feb 11.
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Full-length title: Introduction into the Marseille geographical area of a mild SARS-CoV-2 variant originating from sub-Saharan Africa: an investigational study.
Colson Philippe et al. Travel medicine and infectious disease 2021 Jan 101980 -
A SARS-CoV-2 Cluster in an Acute Care Hospital.
Michael Klompas et al. Ann Intern Med 2021 2 (6) 794-802
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Donor To Recipient Transmission Of SARS-CoV-2 By Lung Transplantation Despite Negative Donor Upper Respiratory Tract Testing.
Kaul D R et al. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Feb
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Whole-genome analysis to describe a Human Adenovirus D8 conjunctivitis outbreak in a tertiary hospital.
Miro Elisenda et al. Journal of medical virology 2021 Feb
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Deciphering an Adenovirus F41 outbreak in hematopoietic stem cell transplant paediatric recipients by whole genome sequencing
Lefeuvre C, et al. J Clin Microbiol. 2021 Feb 10;JCM.03148-20.
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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The identification of novel immunogenic antigens as potential Shigella vaccine components.
de Alwis Ruklanthi et al. Genome medicine 2021 Jan (1) 8 -
The feasibility of targeted test-trace-isolate for the control of SARS-CoV-2 variants
Bradshaw WJ, et al. medRxiv, Feb 8, 2021. -
Decreased SARS-CoV-2 viral load following vaccination
Levine-Tiefenbrun M, et al. medRxiv, Feb 8, 2021.
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Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera.
Xie Xuping et al. Nature medicine 2021 Feb -
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants.
Wang Zijun et al. Nature 2021 Feb
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Efficacy of ChAdOx1 nCoV-19 (AZD1222) Vaccine Against SARS-CoV-2 VOC 202012/01 (B.1.1.7)
Emary KR, et al. Lancet, Feb 4, 2021. -
Antibody Landscape Analysis following Influenza Vaccination and Natural Infection in Humans with a High-Throughput Multiplex Influenza Antibody Detection Assay.
Li Zhu-Nan et al. mBio 2021 Feb (1)
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Rational design of multi epitope-based subunit vaccine by exploring MERS-COV proteome: Reverse vaccinology and molecular docking approach.
Ashfaq Usman Ali et al. PloS one 2021 (2) e0245072
HOST-MICROBE INTERACTIONS
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Differential Expression of Serum Exosome microRNAs and Cytokines in Influenza A and B Patients Collected in the 2016 and 2017 Influenza Seasons.
Othumpangat Sreekumar et al. Pathogens (Basel, Switzerland) 2021 Feb (2)
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice. Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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- Page last updated:Jan 9, 2025