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Public Health Genomics and Precision Health Knowledge Base (v8.2)
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all[original query]>>Original Studies[Product Type]
Integrative genetic analysis illuminates ALS heritability and identifies risk genes.
Megat Salim et al. Nature communications 2023 14(1) 342
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Massive health-record review links viral illnesses to brain disease
M Koslov, Nature, January 23, 2023
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease monitoring.
Ashton Nicholas J et al. Nature medicine 2022
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Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
Holstege Henne et al. Nature genetics 2022
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Genetic and clinical landscape of childhood cerebellar hypoplasia and atrophy.
Sakamoto Masamune et al. Genetics in medicine : official journal of the American College of Medical Genetics 2022
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Diabetes and Alzheimer's disease: shared genetic susceptibility?
J Hardy et al, The Lancet Neurology, November 1, 2022
Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke.
Cho Bernard P H et al. JAMA neurology 2022
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Blood Leukocyte Counts in Alzheimer Disease
J Luo et al, JAMA Network Open
A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study
CY Cheung et al, The Lancet Digital Health, September 30, 2022
Stroke genetics informs drug discovery and risk prediction across ancestries
A Mishra et al, Nature, September 30, 2022
Genome-by-Trauma Exposure Interactions in Adults With Depression in the UK Biobank.
Chuong Melisa et al. JAMA psychiatry 2022
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Estimating individual treatment effect on disability progression in multiple sclerosis using deep learning.
Falet Jean-Pierre R et al. Nature communications 2022 13(1) 5645
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The Vasopressin 1a Receptor Antagonist SRX246 Reduces Aggressive Behavior in Huntington’s Disease
HT Mailbach et al, J Pers Medicine, September 22, 2022
Data-driven causal model discovery and personalized prediction in Alzheimer's disease.
Zheng Haoyang et al. NPJ digital medicine 2022 5(1) 137
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Development and Validation of a Deep Learning Model for Predicting Treatment Response in Patients With Newly Diagnosed Epilepsy
H Hakim et al, JAMA Neurology, August 29, 2022
Artificial intelligence-enabled detection and assessment of Parkinson's disease using nocturnal breathing signals.
Yang Yuzhe et al. Nature medicine 2022
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GPNMB confers risk for Parkinson's disease through interaction with α-synuclein.
Diaz-Ortiz Maria E et al. Science (New York, N.Y.) 2022 377(6608) eabk0637
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Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial.
Feigin Andrew et al. Nature medicine 2022
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Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
Kosoy Roman et al. Nature genetics 2022 54(8) 1145-1154
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Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited.
Koutsouleris Nikolaos et al. JAMA psychiatry 2022
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Shared mechanisms across the major psychiatric and neurodegenerative diseases
TS Wingo et al, Nat Comm, July 26, 2022
Developmental Variability in Autism Across 17 000 Autistic Individuals and 4000 Siblings Without an Autism Diagnosis Comparisons by Cohort, Intellectual Disability, Genetic Etiology, and Age at Diagnosis
SS Kuo et al, JAMA Pediatrics, July 18, 2022
Association of Molecular Senescence Markers in Late-Life Depression With Clinical Characteristics and Treatment Outcome.
Diniz Breno S et al. JAMA network open 2022 5(6) e2219678
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Multimodal deep learning for Alzheimer’s disease dementia assessment
S Qiu et al, Nature Comms, June 20, 2022
Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease
Y Le Guen et al, JAMA Neurology, May 31, 2022
An Exploratory Study Using Electronic Medical Records to Assess the Feasibility of Establishing Cohorts of Patients with Genetic Causes of Parkinson's Disease.
Lee Susan J et al. Journal of Parkinson's disease 2022
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Association of Familial Hypercholesterolemia and Statin Use With Risk of Dementia in Norway.
Mundal Liv J et al. JAMA network open 2022 5(4) e227715
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Disease Progression Stages and Burden in Patients with Duchenne Muscular Dystrophy Using Administrative Claims Supplemented by Electronic Medical Records.
Iff Joel et al. Advances in therapy 2022
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Preconception leisure-time physical activity and family history of stroke and myocardial infarction associate with preterm delivery: findings from a Norwegian cohort.
Engen Tone et al. BMC pregnancy and childbirth 2022 22(1) 341
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Heterozygous and Homozygous Variants in SORL1 Gene in Alzheimer's Disease Patients: Clinical, Neuroimaging and Neuropathological Findings.
Alvarez-Mora Maria Isabel et al. International journal of molecular sciences 2022 23(8)
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Jul 25, 2022
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