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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Reproductive and Child Health
Last data update: Apr 23, 2024
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Stillbirth[original query]>>Reviews/Commentaries[Product Type]
Experts say Found’s story highlights the extraordinary complexity of the problem for pregnant people living with SCD – and the critical importance of receiving proper, specialized care as early as possible. This is especially true now that medical advances in care and disease-modifying therapies have helped many people living with SCD survive well through their reproductive years. For parents-to-be, that means awareness is key. Individuals with SCD are at higher risk than the general population for preeclampsia, as Found discovered; but those with preeclampsia can go on to develop a condition called eclampsia, which can lead to seizures and even coma. People with SCD are also at higher risk for sepsis and blood clots. And there are risks for the fetus, such as lower-than-normal growth in the womb, preterm delivery, and stillbirth.
K Miller, Self, September 2023
Intergenerational trends in reproduction: Infertility and pregnancy loss.
Woolner Andrea Mf et al. Best practice & research. Clinical obstetrics & gynaecology 2023 102305
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Risk Prediction for Stillbirth and Neonatal Mortality in Low-resource Settings.
Shukla Vivek V et al. Newborn (Clarksville, Md.) 2022 1(2) 215-218
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Genomic Insights into Stillbirth
MH Wojick, NEJM, August 12, 2020
Exposure to tobacco smoke and low birth weight: from epidemiology to metabolomics.
Dessì Angelica et al. Expert review of proteomics 2018 Jul
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Genomic testing for the causes of stillbirth should be considered for routine use
Eureka Alert, June 18, 2018
In a Genomic Era, Placental Pathology Still Holds the Key in the Nondysmorphic Stillbirth.
Campbell Jamie et al. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 21(3) 308-318
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Evaluation of stillbirth.
Page Jessica M et al. Current opinion in obstetrics & gynecology 2018 Apr 30(2) 130-135
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Diagnostic utility of microarray testing in pregnancy loss.
Rosenfeld J A et al. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2015 Oct (4) 478-86
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 23, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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