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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: Mar 28, 2024
. (Total: 63390 Documents since 2012)
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Genome-wide association study of osteoporosis identifies genetic risk and interactions with DASH diet and sugar sweetened beverages in a Hispanic cohort of older adults.
Liam E Fouhy et al. J Bone Miner Res 2024
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Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer.
Katherine N Penvose et al. Gynecol Oncol 2023 18191-98
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Physician weight influences responses to a public health message about the genetics of obesity.
Sydney H Telaak et al. Patient Educ Couns 2023 115107853
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Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis
S Zhou et al, Nature Genetics, August 9, 2023
A genome-wide genomic score added to standard recommended stratification tools does not improve the identification of patients with very low bone mineral density.
J Therkildsen et al. Osteoporos Int 2023
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Health status and comorbidities of adult patients with phenylketonuria (PKU) in France with a focus on early-diagnosed patients - A nationwide study of health insurance claims data.
Sybil Charrière et al. Mol Genet Metab 2023 139(3) 107625
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Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot Study.
Beatrice Gasperini et al. Genes 2023 14(3)
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Genome-wide association study identifies genetic variants which predict the response of bone mineral density to teriparatide therapy.
Nerea Alonso et al. Annals of the rheumatic diseases 2023
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Risk-Reducing Breast and Gynecological Surgery for BRCA Mutation Carriers: A Narrative Review.
Serena Bertozzi et al. Journal of clinical medicine 2023 12(4)
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Genome-wide polygenic risk score for major osteoporotic fractures in postmenopausal women using associated single nucleotide polymorphisms.
Qing Wu et al. Journal of translational medicine 2023 21(1) 127
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High frequency of heterozygous rare variants of the SLC34A1 and SLC9A3R1 genes in patients with atypical femur fracture.
Francesca Marini et al. European journal of endocrinology 2023 188(1)
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Risk Variants in or Near ZBTB40 AND NFATC1 Increase the Risk of Both IBD and Adverse Bone Health Outcomes Highlighting Common Genetic Underpinnings Across Both Diseases.
Cushing Kelly C et al. Inflammatory bowel diseases 2023
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The clinical utility of the BMD-related comprehensive genome-wide polygenic score in identifying individuals with a high risk of osteoporotic fractures.
Xiao Xiangxue et al. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2023
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Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis.
Huang Rui et al. Journal of Zhejiang University. Science. B 2022 23(12) 1002-1013
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Bone-Metabolism-Related Serum microRNAs to Diagnose Osteoporosis in Middle-Aged and Elderly Women.
Zhao Sheng-Li et al. Diagnostics (Basel, Switzerland) 2022 12(11)
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Identifying Causes of Fracture Beyond Bone Mineral Density: Evidence from Human Genetics.
Lu Tianyuan et al. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022
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Understanding Musculoskeletal Disorders Through Next-Generation Sequencing.
Garg Bhavuk et al. JBJS reviews 2022 10(4)
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Genetic variants in obesity-related genes and the risk of osteoporotic fracture. The Hortega Follow-up Study.
Usategui-Martín Ricardo et al. Frontiers in bioscience (Landmark edition) 2022 27(1) 32
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Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.
Di Dong-Sheng et al. Frontiers in microbiology 2021 12765008
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The development of a reliable and valid instrument to measure the osteoporosis-related knowledge: validation of the Hungarian version of Osteoporosis Knowledge Assessment Tool (OKAT).
Tardi Peter et al. BMC public health 2021 21(Suppl 1) 1515
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Primum Non Nocere: Should Gene Therapy be Used to Prevent Potentially Fatal Disease but Enable Potentially Destructive Behavior?
Crystal Ronald G et al. Human gene therapy 2021
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The Utility of Genetic Risk Score to Improve Performance of FRAX for Fracture Prediction in US Postmenopausal Women.
Xiao Xiangxue et al. Calcified tissue international 2021 Feb
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Integrative Analysis of Genomics and Transcriptome Data to Identify Regulation Networks in Female Osteoporosis.
Zhang Xianzuo et al. Frontiers in genetics 2020 11600097
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Post-GWAS Polygenic Risk Score: Utility and Challenges.
Nguyen Tuan V et al. JBMR plus 2020 Nov 4(11) e10411
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Comprehensive Genetic Analysis of 128 Candidate Genes in a Cohort With Idiopathic, Severe, or Familial Osteoporosis.
Rocha-Braz Manuela G M et al. Journal of the Endocrine Society 2020 Dec 4(12) bvaa148
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MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Surakka Ida et al. Nature communications 2020 11(1) 4093
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Protocol for a multicentre, prospective cohort study of clinical, proteomic and genomic patterns associated with osteoporosis to develop a multidimensional fracture assessment tool: the PoCOsteo Study.
Khashayar Patricia et al. BMJ open 2020 Sep 10(9) e035363
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Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.
Wei Xin-Tong et al. European journal of human genetics : EJHG 2020 Sep
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Assessing the clinical utility of genetic profiling in fracture risk prediction: a decision curve analysis.
Ho-Le T P et al. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020 Aug
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Burden of disease associated with X-linked hypophosphataemia in adults: a systematic literature review.
Seefried L et al. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020 Jul
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Page last reviewed:
Feb 1, 2024
Page last updated:
Mar 28, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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