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PHGKB Horizon Scan > Genomics Precision Health Scan

Precision Health Database| Genomics Precision Health Scan|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Update Date: Jun 20, 2024
news News and Publications

Birth Defects and Child Health

Social media use by patients with hypermobile Ehlers-Danlos syndrome.
Colin M E Halverson et al. Mol Genet Genomic Med 2024 12(6) e2467

Implications of Provider Specialty, Test Type, and Demographic Factors on Genetic Testing Outcomes for Patients with Autism Spectrum Disorder.
Caitlin N Harrington et al. J Autism Dev Disord 2024

Cancer Genomics

5-Year Real-World Outcomes With Frontline Pembrolizumab Monotherapy in PD-L1 Expression ≥ 50% Advanced NSCLC.
Vamsidhar Velcheti et al. Clin Lung Cancer 2024

Development of a Longitudinal Prostate Cancer Transcriptomic and Clinical Data Linkage.
Michael S Leapman et al. JAMA Netw Open 2024 7(6) e2417274

The REMAR (Rhein-Main-Registry) real-world study: prospective evaluation of the 21-gene breast recurrence score® assay in addition to Ki-67 for adjuvant treatment decisions in early-stage breast cancer.
Christian Jackisch et al. Breast Cancer Res Treat 2024

Chronic Disease

Association between APOA5 polymorphisms and susceptibility to metabolic syndrome: a systematic review and meta-analysis.
Sima Mozafari et al. BMC Genomics 2024 25(1) 590

Genomic Testing in Patients with Kidney Failure of an Unknown Cause: a National Australian Study.
Amali C Mallawaarachchi et al. Clin J Am Soc Nephrol 2024

Ethical, Legal and Social Issues (ELSI)

A contextual integrity approach to genomic information: what bioethics can learn from big data ethics.
Nina F de Groot et al. Med Health Care Philos 2024

General Practice

A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk.
Bradley Jermy et al. Nat Commun 2024 15(1) 5007

Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder.
Lina Jonsson et al. Am J Psychiatry 2024 appiajp20230073

Heart, Lung, Blood and Sleep Diseases

Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk.
Annabelle Santos Volgman et al. J Am Heart Assoc 2024 e033654

Hereditary Cancer

Decision aids for female BRCA mutation carriers: a scoping review.
Sarah A McGarrigle et al. BMJ Open 2024 14(6) e076876

Cost-Effectiveness of Unselected Multigene Germline and Somatic Genetic Testing for Epithelial Ovarian Cancer.
Ranjit Manchanda et al. J Natl Compr Canc Netw 2024 22(2D)

Opportunities for Improving Detection of Cancer Predisposition Syndromes in Pediatric Solid Tumor Patients.
Benjamin Hu et al. J Pediatr Hematol Oncol 2024

A Prospective Questionnaire-Based Study Evaluating Genetic Literacy and Impact of Brief Educational Intervention Among Breast Cancer Patients in a Low- to Middle-Income Country.
Ashutosh Mishra et al. Ann Surg Oncol 2024

Germline Pathogenic Variants Identified in Patients With Genitourinary Malignancies Undergoing Universal Testing: A Multi-Site Single-Institution Prospective Study.
Mouneeb M Choudry et al. J Urol 2024 101097JU0000000000004089

Newborn Screening

Genomic sequencing for newborn screening: current perspectives and challenges.
Nidhi Shah et al. Croat Med J 2024 65(3) 261-267


Pharmacogenomic Characterization of Childbearing-Aged Individuals With Mood Disorders in a Tertiary Care Perinatal Mental Health Clinic.
Jessica L W Mayer et al. J Clin Psychiatry 2024 85(2)

CYP2C19 Genotype Is Associated With Adverse Cardiovascular Outcomes in Black Patients Treated With Clopidogrel Undergoing Percutaneous Coronary Intervention.
Kayla R Tunehag et al. J Am Heart Assoc 2024 e033791

Rationale and design for a pragmatic randomized trial to assess gene-based prescribing for SSRIs in the treatment of depression.
Lindsay J Hines et al. Clin Transl Sci 2024 17(6) e13822

Reproductive Health

An ESHG-ESHRE survey on the current practice of expanded carrier screening in medically assisted reproduction.
Antonio Capalbo et al. Hum Reprod 2024

Pregnant couples' attitude toward extended pre-conceptional genomic screening.
Mojca Ci┼żek Sajko et al. Croat Med J 2024 65(3) 189-197

About Scan

This scan features emerging roles of genomics interventions across the life span. The scan focuses on various conditions including, birth defects, newborn screening, reproductive health, childhood diseases, cancer, chronic diseases, pharmacogenomics, family health history, guidelines and recommendations. The sweep also includes news, reviews, commentaries, tools and database.

Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.