Published on 09/17/2015
Human Genomics across the Lifespan
Birth Defects and Child Health
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Professionally Responsible Disclosure of Genomic Sequencing Results in Pediatric Practice.
McCullough Laurence B et al. Pediatrics 2015 Sep 14. -
Obtaining genetic testing in pediatric epilepsy.
Ream Margie A et al. Epilepsia 2015 Sep 8. -
Genetic testing for pediatric epilepsy can be complicated, but beneficial,
Medical Xpress, September 9, 2015 -
Genomic intensive care: should we perform genome testing in critically ill newborns?
Wilkinson Dominic Jc et al. Arch. Dis. Child. Fetal Neonatal Ed. 2015 Sep 14. -
American society of human genetics updates guidance on genetic testing in children: Group addresses predictive genetic testing, use of secondary findings from genomic sequencing tests.
Am. J. Med. Genet. A 2015 Oct 167(10) viii-ix
Cancer
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Improving Patient Outcomes With Cancer Genomics: Unique Opportunities and Challenges in Pediatric Oncology.
Schnepp Robert W et al. JAMA 2015 Sep 1. 314(9) 881-3 -
Discussing Genetic Testing With Patients With Breast Cancer in Developing Countries: Should We Be Judicious?
Hafeez Bhatti Abu Bakar et al. J. Clin. Oncol. 2015 Sep 14. -
Certified Genetic Counselors: A Crucial Clinical Resource in the Management of Patients with Suspected Hereditary Cancer Syndromes.
Ali-Khan Catts Zohra et al. Surg. Oncol. Clin. N. Am. 2015 Oct 24(4) 653-66 -
Impact of Genetic Counseling in Women with a Family History of Breast Cancer in Italy.
Godino Lea et al. J Genet Couns 2015 Sep 10. -
A targeted approach to genetic counseling in breast cancer patients: the experience of an Italian local project.
La Verde Nicla et al. Tumori 2015 Sep 10. 0(0) 0 -
Securing and Documenting Cancer Family History in the Age of the Electronic Medical Record.
Venne Vickie L et al. Surg. Oncol. Clin. N. Am. 2015 Oct 24(4) 639-52
Chronic Disease
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Optimal Treatment using Statins from Childhood in Heterozygous Familial Hypercholesterolemia.
Nohara Atsushi et al. J. Atheroscler. Thromb. 2015 Sep 15. -
Challenges in the Diagnosis and Treatment of Homozygous Familial Hypercholesterolemia.
Ito Matthew K et al. Drugs 2015 Sep 14. -
Universal Screening for Familial Hypercholesterolemia in Children.
Klancar Gašper et al. J. Am. Coll. Cardiol. 2015 Sep 15. 66(11) 1250-7 -
Frequency of familial hypercholesterolemia in patients with early-onset coronary artery disease admitted to a coronary care unit.
Pang Jing et al. J Clin Lipidol 9(5) 703-8
Ethics/Policy/Law
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Genetic testing of stored tissue from a deceased person to define a relative's disease risk: Legal and ethical viewpoints.
Skene Loane et al. J Law Med 2015 Jun 22(4) 864-70 -
21st-Century Healthcare Policy and the Regulation of Laboratory-Developed Tests.
Caldwell Lexi et al. Genet Test Mol Biomarkers 2015 Sep 19(9) 467-8 -
Stability of Attitudes to the Ethical Issues Raised by the Return of Incidental Genomic Research Findings in Children: A Follow-Up Study.
Fernandez Conrad V et al. Public Health Genomics 2015 Sep 10. -
Confidentiality & the Risk of Genetic Discrimination: What Surgeons Need to Know.
Gammon Amanda et al. Surg. Oncol. Clin. N. Am. 2015 Oct 24(4) 667-81 -
Patenting genetic diagnostic methods: NGS, GWAS, SNPs and patents.
Lawson Charles et al. J Law Med 2015 Jun 22(4) 846-63
Practice
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Discussing the Implications of Genetic Testing With Patients.
Sorscher Steven M et al. J. Clin. Oncol. 2015 Sep 14. -
Genetic Counselors' Perspectives and Practices Regarding Expanded Carrier Screening after Initial Clinical Availability.
Lazarin Gabriel A et al. J Genet Couns 2015 Sep 10. -
Patients' Attitudes Towards Disclosure of Genetic Test Results to Family Members: The Impact of Patients' Sociodemographic Background and Counseling Experience.
Gilbar Roy et al. J Genet Couns 2015 Sep 14. -
ASHG issues statement supporting licensure of genetic counselors,
the American Society of Human Genetics, September 10, 2015 -
Sequence Variants of Uncertain Significance: What to Do When Genetic Test Results Are Not Definitive.
Greenblatt Marc S et al. Surg. Oncol. Clin. N. Am. 2015 Oct 24(4) 833-46
Pharmacogenomics
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Will personalized drugs for cardiovascular disease become an option? - Defining 'Evidence-based personalized medicine' for its implementation and future use.
de Denus Simon et al. Expert Opin Pharmacother 2015 Sep 15. 1-4 -
A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project.
Overby Casey L et al. AMIA Annu Symp Proc 2014 2014944-53 -
Metabolic phenotype prediction from genotyping data: a bottleneck for the implementation of pharmacogenetics in drug development and clinical practice.
LLerena Adrián et al. Drug Metabol Personal Ther 2015 Sep 1. 30(3) 143-5 -
PharmGKB summary: ibuprofen pathways.
Mazaleuskaya Liudmila L et al. Pharmacogenet. Genomics 2015 Feb 25(2) 96-106
Reproductive Health
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Utilization of noninvasive prenatal testing: impact on referrals for diagnostic testing.
Williams John et al. Am. J. Obstet. Gynecol. 2015 Jul 213(1) 102.e1-6 -
UK NHS pilot study on cell-free DNA testing in screening for fetal trisomies: factors affecting uptake.
Gil M M et al. Ultrasound Obstet Gynecol 2015 Jan 45(1) 67-73 -
First-trimester contingent screening for trisomies 21, 18 and 13 by fetal nuchal translucency and ductus venosus flow and maternal blood cell-free DNA testing.
Kagan K O et al. Ultrasound Obstet Gynecol 2015 Jan 45(1) 42-7 -
Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology.
Martin Julio et al. Fertil. Steril. 2015 Sep 3.
News/ Reviews/Comments
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What population genetic diversity can and can't tell us,
by Anne Buchanan, Mermaid?s Tale, September 10, 2015 -
Secrets of longevity may lie in long-lived smokers, a 'biologically distinct' group with extraordinary gene variants,
by Ariana Eunjung Cha, Washington Post, September 10 -
How privacy law affects medical and scientific research,
by John Conley, Genomics Law Report, September 1, 2015 -
CRISPR genome editing 'an important tool',
BBC News, September 10, 2015 -
Screening all women for breast cancer genes not feasible: Study,
Health Day, September 11, 2015 -
Why I'm sceptical about the idea of genetically inherited trauma,
by Ewan Birney, the Guardian, September 11, 2015 -
Who should decide? The complex ethics of pediatric genome sequencing,
by Bruce Agnew, NHGRI, September 14, 2015 -
Human genetic diversity and social inequalities,
Genes to Genomes Blog, September 9, 2015 -
Pathway launches 'liquid biopsy' to find cancer in healthy people,
by Julie Steenhuysen, Reuters, September 10, 2015 -
Sifting DNA databases for the right diagnosis,
by Michelle Cortez, Bloomberg, September 10, 2015 -
Money matters: shaping the use of genomics in the NHS,
by Dr Gurdeep Sagoo, PHG Foundation, September 17, 2015 -
Undiagnosed Diseases Network launches online application portal,
NIH News, September 16, 2015 -
Why you shouldn't know too much about your own genes,
by Carolyn Johnson, Washington Post, September 11, 2015