Published on 08/28/2015
Human Genomics across the Lifespan
Birth Defects and Child Health
What is the role of clinical genetics in the patient-centered medical home?: A commentary from the Medical Home Workgroup of the Heartland Regional Genetics and Newborn Screening Collaborative.
Schaefer Gerald Bradley et al. Genet. Med. 2015 Aug 20.
Development and Validation of a Next-Generation Sequencing Assay for BRCA1 and BRCA2 Variants for the Clinical Laboratory.
Strom Charles M et al. PLoS ONE 2015 10(8) e0136419
Screening Strategies for Colorectal Cancer among Patients with Non-Alcoholic Fatty Liver Disease and Family History.
Wong Martin Cs et al. Int. J. Cancer 2015 Aug 20.
Efficacy of a web-based intelligent tutoring system for communicating genetic risk of breast cancer: a fuzzy-trace theory approach.
Wolfe Christopher R et al. Med Decis Making 2015 Jan 35(1) 46-59
Next-Generation Sequencing and Detection of Minimal Residual Disease in Acute Myeloid Leukemia: Ready for Clinical Practice?
Pastore Friederike et al. JAMA 2015 Aug 25. 314(8) 778-780
Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
Klco Jeffery M et al. JAMA 2015 Aug 25. 314(8) 811-822
The role of germline mutations in the BRCA1/2 and mismatch repair genes in men ascertained for early-onset and/or familial prostate cancer.
Maia Sofia et al. Fam. Cancer 2015 Aug 20.
NCI-MATCH launch highlights new trial design in precision-medicine era.
McNeil Caroline et al. J. Natl. Cancer Inst. 2015 Jul 107(7)
Initial medical policy and model coverage guidelines for clinical NGS in oncology, [PDF 965.34 KB]
Green Park Collaborative, Aug 17, 2015
Is it time to offer BRCA1 and BRCA2 testing to all Jewish women?
Metcalfe K A et al. Curr Oncol 2015 Aug 22(4) e233-6
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer.
Garcia-Murillas Isaac, et al. Science translational medicine 2015 8 0. (302) 302ra133
Does molecular monitoring matter in early-stage breast cancer?
Sundaresan Tilak K, et al. Science translational medicine 2015 8 0. (302) 302fs35
New 'mutation-tracking' blood test could predict breast cancer relapse months in advance,
the Institute of Cancer Research, Aug 26, 2015
Women with double primary cancers of the colorectum and endometrium: do they have Lynch syndrome?
Song Taejong et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 2015 Aug 19.
Rescreening for genetic mutations using multi-gene panel testing in patients who previously underwent non-informative genetic screening.
Frey Melissa K et al. Gynecol. Oncol. 2015 Aug 18.
If three of my brothers have ankylosing spondylitis, why does the doctor say it is not necessarily hereditary? The meaning of risk in multiplex case families with ankylosing spondylitis.
PelÃ¡ez-Ballestas Ingris et al. Chronic Illn 2015 Aug 19.
The genomic landscape of human immune-mediated diseases.
Wu Xin et al. J. Hum. Genet. 2015 Aug 20.
A Systematic Review on the Cost-Effectiveness of Genetic and Electrocardiogram Testing for Long QT Syndrome in Infants and Young Adults.
Gonzalez Fernando Matias et al. Value Health 2015 Jul 18(5) 700-8
Military Health Care Dilemmas and Genetic Discrimination: A Family's Experience with Whole Exome Sequencing.
Helm Benjamin M et al. Narrat Inq Bioeth 2015 5(2) 179-86
Pharmacogenomics, human genetic diversity and the incorporation and rejection of color/race in Brazil.
Santos Ricardo Ventura et al. Biosocieties 2015 Mar 1. 10(1) 48-69
Ethical considerations in presymptomatic diagnosis of autosomal dominant spinocerebellar ataxias.
Orozco-Gutiérrez M H et al. Neurologia 2015 Aug 21.
The Limits of FDA's Authority to Regulate Clinical Research Involving High-Throughput DNA Sequencing.
Evans Barbara J et al. Food Drug Law J 2015 70(2) 259-87, ii
An Unfulfilled Promise: Changes Needed to the Drug Approval Process to Make Personalized Medicine a Reality.
Riley Margaret Foster et al. Food Drug Law J 2015 70(2) 289-314, ii-iii
The gene patent controversy on Twitter: a case study of Twitter users' responses to the CHEO lawsuit against Long QT gene patents.
Du Li et al. BMC Med Ethics 2015 1655
Pregnant patients' risk perception of prenatal test results with uncertain fetal clinical significance: ultrasound versus advanced genetic testing.
Richards Elliott G et al. Prenat. Diagn. 2015 Aug 19.
The new world of genomic testing, families and privacy.
Wolf Susan M et al. Minn Med 2015 Jun 98(6) 32-4
Screening for cystic fibrosis in New York State: considerations for algorithm improvements.
Kay Denise M et al. Eur. J. Pediatr. 2015 Aug 21.
Physicians' opinions following pharmacogenetic testing for psychotropic medication.
Walden Lucas M et al. Psychiatry Res 2015 Aug 7. PSYD1500197
The evolution of prenatal genetic screening.
Gross Susan et al. MLO Med Lab Obs 2015 May 47(5) 14
Next steps in developing the Precision Medicine Initiative,
the White House, Aug 21, 2015
New guidelines to help payers navigate NGS testing in cancer,
by Roxanne Nelson, Medscape, Aug 19, 2015 [by free subscription only]
Genetic testing can lead to insights - or uncertainty,
by Lauren M. Green, Cure, Aug 13, 2015
Biohackers gear up for genome editing,
by Heidi Ledford, Nature News, Aug 26, 2015
The DNA of a nation.
Marx Vivien, et al. Nature 2015 8 0. (7566) 503-5
Everything You Need to Know About Precision Medicine,
by Alexandra Ossola, Popular Science, Aug 27, 2015
The Mystery of Jimmy Carters Cancer,
the Daily Beast, Aug 20, 2015
New international effort to uncover schizophrenia genomics,
by Dr Philippa Brice, PHG Foundation, Aug 20, 2015
It's complicated: genomics, obesity and diabetes,
Genomics Education Programme, Aug 17, 2015