Last Posted: Nov 07, 2015
- Gene copy-number variations (CNVs) of complement C4 and C4A deficiency in genetic risk and pathogenesis of juvenile dermatomyositis.
Lintner Katherine E, et al. Annals of the rheumatic diseases 2015 10
- Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.
Miller F W, et al. Genes and immunity 2015 8
- Juvenile dermatomyositis
From NCATS Genetic and Rare Diseases Information Center
- Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis.
Gunawardena H, et al. Arthritis and rheumatism 2009 6 (6) 1807-14
- Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis.
Mamyrova Gulnara, et al. Arthritis and rheumatism 2008 12 (12) 3941-50
- Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis.
Christen-Zaech Stéphanie, et al. Arthritis and rheumatism 2008 2 (2) 571-6
- HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap.
Wedderburn L R, et al. Rheumatology (Oxford, England) 2007 12 (12) 1786-91
- Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians.
Mamyrova Gulnara, et al. Arthritis and rheumatism 2006 12 (12) 3979-87
- Increased plasma thrombospondin-1 (TSP-1) levels are associated with the TNF alpha-308A allele in children with juvenile dermatomyositis.
Lutz Jennica, et al. Clinical immunology (Orlando, Fla.) 2002 6 (3 Pt 1) 260-3
Rare Disease PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other information that address the public health impact and translation of genomic and other precision health discoveries into improved health outcomes related to rare diseases...more
Selected Rare Diseases
- Alpha-1 Antitrypsin Deficiency
- Amyotrophic Lateral Sclerosis
- Brugada Syndrome
- Cerebral Palsy
- Cystic Fibrosis
- Duchenne Muscular Dystrophy
- Erythema Multiforme
- Familial Mediterranean Fever
- Fragile X Syndrome
- Gaucher Disease
- Graves Disease
- Huntington Disease
- Myasthenia Gravis
- Retinitis Pigmentosa
- Severe Combined Immunodeficiency
Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.