Last Posted: Apr 18, 2024
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Latest News and Publications
Advanced practice nurse pharmacogenomics capacity and utilization.
Cathy R Fulton et al. J Am Assoc Nurse Pract 2024
Olaparib not cost-effective as maintenance therapy for platinum-sensitive, BRCA1/2 germline-mutated metastatic pancreatic cancer.
Tarun Mehra et al. PLoS One 2024 19(4) e0301271
Patient perspectives on pharmacogenomic (PGx) testing for antidepressant prescribing in primary care: a qualitative description study.
Alexandra Cernat et al. J Community Genet 2024
The role of community engagement in promoting research participants' understanding of pharmacogenomic research results: Perspectives of stakeholders involved in HIV/AIDS research and treatment.
Sylvia Nabukenya et al. PLoS One 2024 19(4) e0299081
A New Cloud-Native Tool for Pharmacogenetic Analysis.
David Yu Yuan et al. Genes (Basel) 2024 15(3)
Implementation of CYP2C19 and CYP2D6 genotyping to guide antidepressant use in a large rural health system.
Natasha J Petry et al. Am J Health Syst Pharm 2024
Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea.
Ki Young Huh et al. Clin Transl Sci 2024 17(3) e13772
Clinical evaluation of a low-coverage whole-genome test for detecting homologous recombination deficiency in ovarian cancer.
Romain Boidot et al. Eur J Cancer 2024 202113978
Clinical pharmacists' knowledge, attitude, perception, and beliefs about the role of pharmacogenetic testing for genes polymorphisms when prescribing mercaptopurine.
Norah O Abanmy et al. Saudi Pharm J 2024 32(4) 102022
Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders.
Maike Scherf-Clavel et al. World J Biol Psychiatry 2024 1-11
Real-World Data and Clinical Implications of Next-Generation Sequencing (NGS)-Based Analysis in Metastatic Breast Cancer Patients.
Fabio Canino et al. Int J Mol Sci 2024 25(5)
Empowering personalized pharmacogenomics with generative AI solutions.
Mullai Murugan et al. J Am Med Inform Assoc 2024
Exploring the impact and utility of genomic sequencing in established CKD.
Julia Jefferis et al. Clin Kidney J 2024 17(3) sfae043
The cost-effectiveness of germline BRCA testing-guided olaparib treatment in metastatic castration resistant prostate cancer.
Srinivas Teppala et al. Int J Technol Assess Health Care 2024 40(1) e14
Knowledge and attitudes on implementing cardiovascular pharmacogenomic testing.
Callan Russell et al. Clin Transl Sci 2024 17(3) e13737
A survey on awareness, knowledge and preferences toward genetic testing among the United States general public.
Shahariar Mohammed Fahim et al. Per Med 2024
Contemporary lipid-lowering management and risk of cardiovascular events in homozygous familial hypercholesterolaemia: insights from the Italian LIPIGEN Registry.
Laura D'Erasmo et al. Eur J Prev Cardiol 2024
Impact on costs and outcomes of multi-gene panel testing for advanced solid malignancies: a cost-consequence analysis using linked administrative data.
Alberto Hernando-Calvo et al. EClinicalMedicine 2024 69102443
PillHarmonics™: An Orchestrated Pharmacogenetics Medication Clinical Decision Support Service.
Robert H Dolin et al. Appl Clin Inform 2024
A Bayesian approach for investigating the pharmacogenetics of combination antiretroviral therapy in people with HIV.
Wei Jin et al. Biostatistics 2024
Opportunities for Pharmacogenetic Testing to Guide Dosing of Medications in Youths With Medicaid.
Sonya Tang Girdwood et al. JAMA Netw Open 2024 7(2) e2355707
An update review of new therapies in sickle cell disease: the prospects for drug combinations.
Sanne Lugthart et al. Expert Opin Pharmacother 2024
Genetic and non-genetic predictors of risk for opioid dependence.
Peter J Na et al. Psychol Med 2024 1-8
Using Machine Learning to Determine a Suitable Patient Population for Anakinra for the Treatment of COVID-19 Under the Emergency Use Authorization.
Liu Qi, et al. Clinical pharmacology and therapeutics 2024 0 0.
Assessing the utility of measurement methods applied in economic evaluations of pharmacogenomics applications.
Vasileios Fragoulakis et al. Pharmacogenomics 2024
Measuring Costs of Cardiovascular Disease Prevention for Patients with Familial Hypercholesterolemia in Administrative Claims Data.
Lauren E Passero et al. High Blood Press Cardiovasc Prev 2024
Modeling health outcomes associated with BRCA testing and treatment strategies for patients with metastatic pancreatic cancer.
Neeharika Agnihotri et al. Pancreatology 2024
Use of drugs with pharmacogenomics (PGx)-based dosing guidelines in a Danish cohort of persons with chronic kidney disease, both on dialysis and not on dialysis: Perspectives for prescribing optimization.
Niels Westergaard et al. Basic Clin Pharmacol Toxicol 2024
Effects of Social Determinants and Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions.
Sean David et al. Ann Fam Med 2024 21(Suppl 3)
Implementation of clopidogrel pharmacogenetic clinical decision support for a preemptive return of results program.
Christina L Aquilante et al. Am J Health Syst Pharm 2024
Next-generation sequencing in pharmacogenomics - fit for clinical decision support?
Yitian Zhou et al. Expert Rev Clin Pharmacol 2024
The landscape of the methodology in drug repurposing using human genomic data: a systematic review.
Lijuan Wang et al. Brief Bioinform 2024 25(2)
Therapeutic Drug Monitoring and Pharmacogenetic Testing as Guides to Psychotropic Drug Dose Adjustment: An Observational Study.
Elodie Cuvelier et al. Pharmaceuticals (Basel) 2024 17(1)
Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine.
Laura K Wiley et al. Am J Hum Genet 2024 111(1) 11-23
Implementing HLA-B*58:01 testing prior to allopurinol initiation in Malaysian primary care setting: A qualitative study from doctors' and patients' perspective.
Wei Leik Ng et al. PLoS One 2024 19(1) e0296498
Modern approaches to the management of homozygous familial hypercholesterolemia in the Middle East and North Africa.
Abdullah Al-Ashwal et al. J Clin Lipidol 2023
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study.
Elise Koch et al. Neuropsychopharmacology 2024
Identification of oral therapeutics using an AI platform against the virus responsible for COVID-19, SARS-CoV-2.
Bess Adam, et al. Frontiers in pharmacology 2024 0 0. 1297924
Documentation of results and medication prescribing after combinatorial psychiatric pharmacogenetic testing: a case for discrete results.
John Loftus et al. Genet Med 2023 101056
Prevalent Variants in the LDLR Gene Impair Responsiveness to Rosuvastatin among Family Members of Patients with Premature Myocardial Infarction.
Nguyen Trung Kien et al. J Pers Med 2023 13(12)
Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.
Beverly Kyalwazi et al. JAMA Netw Open 2023 6(12) e2349646
Returning personalized, genetic health test results to individuals of African descent or ancestry in precision medicine research.
Rachele M Hendricks-Sturrup et al. Health Aff Sch 2023 1(6) qxad066
Sotorasib versus Docetaxel for treatment of US and Chinese patients with advanced non-small-cell lung cancer with KRAS p.G12C-mutated: A cost-effectiveness analysis to inform drug pricing.
Yunlin Jiang et al. Medicine (Baltimore) 2023 102(50) e36387
A Narrative Review on Pharmacogenomics in Psychiatry: Scientific Definitions, Principles, and Practical Resources.
Sara Palumbo et al. J Clin Psychopharmacol 2023 44(1) 49-56
Implementing a Pharmacogenomic-driven Algorithm to Guide Antiplatelet Therapy among Caribbean Hispanics: A non-randomized prospective cohort study.
Héctor Nuñez-Medina et al. medRxiv 2023
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges.
Irene García et al. Expert Rev Clin Pharmacol 2023
Influence of pharmacogenetics on the diversity of response to statins associated with adverse drug reactions.
Jaime I Sainz de Medrano Sainz et al. Adv Lab Med 2023 4(4) 341-352
Life-Saving Treatments for Spinal Muscular Atrophy: Global Access and Availability.
Victor D Armengol et al. Neurol Clin Pract 2023 14(1) e200224
Personalized medicine in a community health system: the NorthShore experience.
Sean P David et al. Front Genet 2023 141308738
A simplified risk scoring system for predicting high-risk groups in gene expression tests for patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative, and node-positive breast cancer.
Kwang Hyun Yoon et al. Ann Surg Treat Res 2023 105(6) 360-368
Ancestry, race and ethnicity: the role and relevance of language in clinical genetics practice.
Melody Grace Redman et al. J Med Genet 2023
Misperceptions and management of LDL-cholesterol in secondary prevention of patients with familial hypercholesterolemia in cardiology practice: Real-life evidence from the EPHESUS registry.
Meral Kayikcioglu et al. J Clin Lipidol 2023 17(6) 732-742
Omission of Radiotherapy After Breast-Conserving Surgery for Women With Breast Cancer With Low Clinical and Genomic Risk: 5-Year Outcomes of IDEA.
Reshma Jagsi et al. J Clin Oncol 2023 JCO2302270
A systematic review of knowledge, attitude and practice of pharmacogenomics in pediatric oncology patients.
Claire Moore et al. Pharmacol Res Perspect 2023 11(6) e01150
Feasibility of preemptive pharmacogenetic testing and improvement of medication treatment satisfaction among medically underserved patients.
Christelle Lteif et al. Clin Transl Sci 2023
Impact of CYP2C19 Genotype on Efficacy and Safety of Clopidogrel-based Antiplatelet Therapy in Stroke or Transient Ischemic Attack Patients: An Updated Systematic Review and Meta-analysis of Non-East Asian Studies.
Sarah Cargnin et al. Cardiovasc Drugs Ther 2023
An EMR-Based Approach to Determine Frequency, Prescribing Pattern, and Characteristics of Patients Receiving Drugs with Pharmacogenomic Guidelines.
George E MacKinnon et al. Pharmacy (Basel) 2023 11(6)
Are Community Pharmacists Ready to Deliver Pharmacogenomics Testing Services?
Heba Ghazal et al. Pharmacy (Basel) 2023 11(6)
Clinical pharmacology and pharmacogenomics for implementation of personalized medicine.
Ashwin Kamath et al. Pharmacogenomics 2023
Cost-effectiveness of pharmacogenomic-guided treatment for major depression.
Shahzad Ghanbarian et al. CMAJ 2023 195(44) E1499-E1508
Healthcare professionals' and consumers' knowledge, attitudes, perspectives, and education needs in oncology pharmacogenomics: A systematic review.
Chiao Xin Lim et al. Clin Transl Sci 2023
Impact of Pharmacogenomics in Clinical Practice.
Nicola Principi et al. Pharmaceuticals (Basel) 2023 16(11)
Nomogram Update to Predict the High Genomic Risk Breast Cancer by Different Races.
Peng Wu et al. Clin Breast Cancer 2023
Patient-Level Exposure to Actionable Pharmacogenomic Medications in a Nationally Representative Insurance Claims Database.
Monica L Bianchini et al. J Pers Med 2023 13(11)
Should Secondary Pharmacogenomic Variants Be Actively Screened and Reported When Diagnostic Genome-Wide Sequencing Is Performed in a Child?
Jan M Friedman et al. Genet Med 2023 101033
A DNA Replication Stress-Based Prognostic Model for Lung Adenocarcinoma.
S Shi et al. Acta Naturae 2023 15(3) 100-110
Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity.
Stefan Stewart et al. Front Pharmacol 2023 141292416
Pharmacogenomics in clinical trials: an overview.
Rita Nogueiras-Álvarez et al. Front Pharmacol 2023 141247088
Determination of Novel SARS-CoV-2 Inhibitors by Combination of Machine Learning and Molecular Modeling Methods.
Güner Ersin, et al. Medicinal chemistry (Shariqah (United Arab Emirates)) 2023 0 0.
Implementation of Pharmacogenetics in First-Line Care: Evaluation of Its Use by General Practitioners.
Denise van der Drift et al. Genes (Basel) 2023 14(10)
Patient and health care professional acceptability of pharmacogenetic screening for DPYD and UGT1A1: a cross sectional survey.
Sarah Glewis et al. Clin Transl Sci 2023
Pharmacogenetic testing may benefit people receiving low-dose lithium in clinical practice.
Michael Ray Dickerson et al. J Am Assoc Nurse Pract 2023
Population Pharmacogenomics for Health Equity.
I King Jordan et al. Genes (Basel) 2023 14(10)
The Clinical Implementation of CYP2C19 Genotyping in Patients with an Acute Coronary Syndrome: Insights From the FORCE-ACS Registry.
Jaouad Azzahhafi et al. J Cardiovasc Pharmacol Ther 2023 2810742484231210704
Cost-utility analysis and cross-country comparison of pharmacogenomics-guided treatment in colorectal cancer patients participating in the U-PGx PREPARE study.
Vasileios Fragoulakis et al. Pharmacol Res 2023 106949
Diagnosis and Treatment of Advanced ALK Rearrangement-Positive Non-Small-Cell Lung Cancer in Portugal: Results of a National Questionnaire.
Ana Figueiredo et al. Drugs Real World Outcomes 2023
Evaluation of malignant hyperthermia features in patients with pathogenic or likely pathogenic RYR1 variants disclosedthrough a population genomic screening program.
Kristen D Yu et al. Anesthesiology 2023
Introduction to pharmacogenetics.
John Henry McDermott et al. Drug Ther Bull 2023
Pharmacogenetics to prevent hypersensitivity reactions to antiepileptic drugs: is testing performed when indicated?
Vy L Bui et al. Pharmacogenet Genomics 2023
Real-World Cost Effectiveness of a Policy of KRAS Testing to Inform Cetuximab or Panitumumab for Third-Line Therapy of Metastatic Colorectal Cancer in British Columbia, Canada.
Reka E Pataky et al. Pharmacoecon Open 2023
Discordance of Oncotype DX scores in synchronous bilateral and unilateral multifocal breast cancers.
Jing Wang et al. Breast Cancer Res Treat 2023
Genetic counseling graduate program faculty perspectives on sharing education materials among programs.
E Emma Murphy et al. J Genet Couns 2023
Long-term safety and effectiveness of alirocumab and evolocumab in familial hypercholesterolemia (FH) in Belgium.
Marc Snel et al. Acta Cardiol 2023 1-8
Patient Perspectives of Barriers and Facilitators for the Uptake of Pharmacogenomic Testing in Veterans Affairs' Pharmacogenomic Testing for the Veterans (PHASER) Program.
Karina Melendez et al. J Pers Med 2023 13(9)
Premature atherosclerosis: An analysis over 39 years in the Netherlands. Implications for young individuals in high-risk families.
Juliette Crooijmans et al. Atherosclerosis 2023 117267
Review of pharmacogenomics of psychiatric comorbidities in autism spectrum disorder.
Aida Alvarez et al. Pharmacogenomics 2023
Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer.
Raphaël Leman et al. Clin Cancer Res 2023 OF1-OF11
An evidence-based debate on epigenetics and immunosenescence in COVID-19.
Napoli Claudio, et al. Current research in immunology 2023 0 0. 100069
Impact of Treatment with Ustekinumab on Severe Infections in a Patient with Uncontrolled Psoriasis and Late-Onset Combined Primary Immunodeficiency: Case Report.
Prestes-Carneiro Luiz Euribel, et al. Pathogens (Basel, Switzerland) 2023 0 0. (9)
Use of whole genome sequencing to identify low-frequency mutations in SARS-CoV-2 patients treated with remdesivir.
Kuganya Nirmalarajah et al. Influenza Other Respir Viruses 2023 9 (9) e13179
Omicron variant dominance and anti-SARS-CoV-2 vaccination are key determinants for a milder course of COVID-19 in patients with systemic autoimmune rheumatic diseases.
Papagoras Charalampos, et al. Clinical rheumatology 2023 0 0.
Clinician Response to Pharmacogenetic Clinical Decision Support Alerts.
Lauren K Lemke et al. Clin Pharmacol Ther 2023
Current Practices in Pharmacogenomics.
Laura B Ramsey et al. Pediatr Clin North Am 2023 70(5) 995-1011
CYP2D6-guided opioid therapy for adults with cancer pain: a randomized implementation clinical trial.
Scott A Mosley et al. Pharmacotherapy 2023
PharmVar Tutorial on CYP2D6 Structural Variation Testing and Recommendations on Reporting.
Amy J Turner et al. Clin Pharmacol Ther 2023
Association of regular use of ibuprofen and paracetamol, genetic susceptibility, and new-onset dementia in the older population.
Yuanyuan Zhang et al. Gen Hosp Psychiatry 2023 84226-233
Cost-effectiveness of preventive aspirin use and intensive downstaging polypectomy in patients with familial adenomatous polyposis: A microsimulation modeling study.
Eiko Saito et al. Cancer Med 2023
Editorial: Editor's feature: negative findings in pharmacogenetics and pharmacogenomics.
José A G Agúndez et al. Front Pharmacol 2023 141267344
The Value of Pharmacogenomics for White and Indigenous Americans after Kidney Transplantation.
Alexandra Brady et al. Pharmacy (Basel) 2023 11(4)
Impact of different classes of immune-modulating treatments on B cell-related and T cell-related immune response before and after COVID-19 booster vaccination in patients with immune-mediated diseases and primary immunodeficiency: a cohort study.
Koehm Michaela, et al. RMD open 2023 0 0. (3)
Effect of vitamin D receptor gene BsmI polymorphism on hospitalization of SARS-CoV-2 positive patients.
Aci Recai, et al. Nucleosides, nucleotides & nucleic acids 2023 0 0. 1-12
A study on the effect of natural products against the transmission of B.1.1.529 Omicron.
Alkafaas Samar Sami, et al. Virology journal 2023 0 0. (1) 191
Cost-Effectiveness Analysis of Pharmacogenomics (PGx)-Based Warfarin, Apixaban, and Rivaroxaban Versus Standard Warfarin for the Management of Atrial Fibrillation in Ontario, Canada.
Aneeka Hafeez et al. Pharmacoeconomics 2023
Effectiveness of pharmacogenomics educational interventions on healthcare professionals and health professions students: A systematic review.
Safa Omran et al. Res Social Adm Pharm 2023
Integrating Genome-wide information and Wearable Device Data to Explore the Link of Anxiety and Antidepressants with Heart Rate Variability.
Eleni Friligkou et al. medRxiv 2023
T790M detection rate after first-line combination therapy with bevacizumab and EGFR-TKIs in advanced NSCLC (TERRA Study).
Chih-Hsi Scott Kuo et al. Am J Cancer Res 2023 13(7) 3100-3112
Which Patients Do We Need to Test for BRCA1/2 Mutation? Feasibility of Adjuvant Olaparib Treatment in Early Breast Cancer-Real-World Data from Two Large German Breast Centers.
Dominik Dannehl et al. Cancers (Basel) 2023 15(15)
CYP19A1 mediates severe SARS-CoV-2 disease outcome in males.
Stanelle-Bertram Stephanie, et al. Cell reports. Medicine 2023 0 0. 101152
The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants.
Naushad Shaik Mohammad, et al. Scientific reports 2023 0 0. (1) 13078
Identification of Sociodemographic, Clinical, and Genetic Factors to Aid Alaska Native and American Indian People to Successfully Quit Smoking.
Jaedon P Avey et al. Nicotine Tob Res 2023
Pharmacogenetics: ethnicity, treatment and health in Latin American populations.
Martha Sosa-Macías et al. Pharmacogenomics 2023
Providers' Use of Pharmacogenetic Testing to Inform Antidepressant Prescribing: Results of Qualitative Interviews.
Bonnie M Vest et al. Psychiatr Serv 2023 0
Predicting adverse outcomes in pregnant patients positive for SARS-CoV-2: a machine learning approach- a retrospective cohort study.
Young Dylan, et al. BMC pregnancy and childbirth 2023 0 0. (1) 553
The plasma metabolome of long COVID patients two years after infection.
López-Hernández Yamilé, et al. Scientific reports 2023 0 0. (1) 12420
At-Risk Genomic Findings for Pediatric-Onset Disorders From Genome Sequencing vs Medically Actionable Gene Panel in Proactive Screening of Newborns and Children.
Jorune Balciuniene et al. JAMA Netw Open 2023 6(7) e2326445
Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2, and CYP2C9 variants.
K Ivar Lönnberg et al. Pharmacogenet Genomics 2023
Omicron variant infection in inflammatory rheumatological conditions - outcomes from a COVID-19 naive population in Aotearoa New Zealand.
Brooks Jonathon, et al. The Lancet regional health. Western Pacific 2023 0 0. 100843
Actionable molecular alterations in newly diagnosed and recurrent IDH1/2 wild-type glioblastoma patients and therapeutic implications: a large mono-institutional experience using extensive next-generation sequencing analysis.
Marta Padovan et al. Eur J Cancer 2023 191112959
Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website.
Andrea M Mosquera et al. CourseSource 2023 10
Evidence and Recommendation for Guanidinoacetate Methyltransferase Deficiency Newborn Screening.
Margie A Ream et al. Pediatrics 2023
The Genetic Testing Reference Materials Coordination Program: Over 10 Years of Support for Pharmacogenomic Testing.
Stuart A Scott et al. J Mol Diagn 2023
UGT1A1 genotype-guided dosing of irinotecan: time to prioritize patient safety.
Sofía Lj Peeters et al. Pharmacogenomics 2023
Assessing Clinical Utility of Pharmacogenetic Testing in the Military Health System.
Lydia D Hellwig et al. Mil Med 2023
Congruence rates for pharmacogenomic noninterruptive alerts.
Sarah C Mills et al. Pharmacogenomics 2023
Importance of ROS1 gene fusions in non-small cell lung cancer.
Meri Muminovic et al. Cancer Drug Resist 2023 6(2) 332-344
Prescription medications with actionable pharmacogenomic recommendations in Veterans Health Administration patients.
Saba Maghari et al. Pharmacogenomics 2023
CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.
Victoria M Pratt et al. J Mol Diagn 2023
Lack of guidelines and translational knowledge is hindering the implementation of psychiatric genetic counseling and testing within Europe - A multi-professional survey study.
Kati Koido et al. Eur J Med Genet 2023 104805
Identifying hub genes and common biological pathways between COVID-19 and benign prostatic hyperplasia by machine learning algorithms.
Zhou Hang, et al. Frontiers in immunology 2023 0 0. 1172724
Real life treatment experience and outcome of consecutively hospitalised patients with SARS-CoV-2 pneumonia by Omicron-1 vs Delta variants.
Giannitsioti Efthymia, et al. Infectious diseases (London, England) 2023 0 0. 1-10
SARS-CoV-2 Covid-19 Infection During Pregnancy and Differential DNA Methylation in Human Cord Blood Cells From Term Neonates.
Urday Pedro, et al. Epigenetics insights 2023 0 0. 25168657231184665
Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person's Medication Experience and Ethics.
Timothy P Stratton et al. Pharmacy (Basel) 2023 11(3)
Pharmacogenetic Sex-Specific Effects of Methotrexate Response in Patients with Rheumatoid Arthritis.
Francisco C Ceballos et al. Pharmaceutics 2023 15(6)
Pharmacogenetics of Lethal Opioid Overdose: Review of Current Evidence and Preliminary Results from a Pilot Study.
Leen Magarbeh et al. J Pers Med 2023 13(6)
Polygenic risk scores in pharmacogenomics: opportunities and challenges-a mini review.
Aurélien Simona et al. Front Genet 2023 141217049
Real Evidence and Misconceptions about Malignant Hyperthermia in Children: A Narrative Review.
Luciano Frassanito et al. J Clin Med 2023 12(12)
Risk-conferring HLA variants in an epilepsy cohort: benefits of multifaceted use of whole genome sequencing in clinical practice.
Angeliki Vakrinou et al. J Neurol Neurosurg Psychiatry 2023
Utilization of genetic information for medicines development and equitable benefit sharing.
Kotone Matsuyama et al. Front Genet 2023 141085864
Knowledge mapping of COVID-19 and autoimmune diseases: a visual and bibliometric analysis.
Zhang Youao, et al. Clinical and experimental medicine 2023 0 0.
Proteomic Investigation of COVID-19 Severity During the Tsunamic Second Wave in Mumbai.
Rajoria Sakshi, et al. Advances in experimental medicine and biology 2023 0 0. 175-195
Circulating microRNA profile in response to remdesivir treatment in coronavirus disease 2019 (COVID-19) patients.
Fayyad-Kazan Mohammad, et al. Archives of virology 2023 0 0. (7) 194
A scoping review of smoking cessation pharmacogenetic studies to advance future research across racial, ethnic, and ancestral populations.
Elizabeth C Prom-Wormley et al. Front Genet 2023 141103966
Characterization of Reference Materials for CYP3A4 and CYP3A5: A GeT-RM Collaborative Project.
Andrea Gaedigk et al. J Mol Diagn 2023
Comparison of pharmacogenomic information for drug approvals provided by the national regulatory agencies in Korea, Europe, Japan, and the United States.
Mijin Lee et al. Front Pharmacol 2023 141205624
Core issues, case studies, and the need for expanded Legacy African American genomics.
Fatimah Jackson et al. Front Genet 2023 14843209
Editorial: The role of pharmacogenomics in addressing health disparities: the path, the promise, and the barriers.
Youssef M Roman et al. Front Genet 2023 141233045
Relationship between CDX2 rs11568820 and EcoRV rs4516035 polymorphisms on the vitamin D receptor gene with susceptibility to different SARS-CoV-2 variants.
Al-Mohammedawi Abed K K, et al. Cell biology international 2023 0 0.
Maintaining the Utility of COVID-19 Pandemic Severity Surveillance: Evaluation of Trends in Attributable Deaths and Development and Validation of a Measurement Tool.
Trottier Caitlin, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023 0 0.
SARS-CoV-2 intrahost evolution in immunocompromised patients in comparison with immunocompetent populations after treatment.
Ahmadi Akram Sadat, et al. Journal of medical virology 2023 0 0. (6) e28877
Bridging the gap between genetic epidemiological research and prevention: A randomized control trial of a novel personalized feedback program for alcohol and cannabis use.
Maia Choi et al. Drug Alcohol Depend 2023 249110818
Home-Based Infusion of Alglucosidase Alfa Can Safely be Implemented in Adults with Late-Onset Pompe Disease: Lessons Learned from 18,380 Infusions.
Imke A M Ditters et al. BioDrugs 2023
Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With ERBB2 Mutation or Amplification: Results From the Targeted Agent and Profiling Utilization Registry Study.
Apar K Ganti et al. JCO Precis Oncol 2023 7e2300041
Pharmacogenetic testing in psychiatry: Perspective on clinical utility.
Frances Adiukwu et al. Asian J Psychiatr 2023 86103674
Upfront DPYD Genotype-Guided Treatment for Fluoropyrimidine-Based Chemotherapy in Advanced and Metastatic Colorectal Cancer: A Cost-Effectiveness Analysis.
Soroush Ahmadi Fariman et al. Value Health Reg Issues 2023 3771-80
Advancing Pharmacogenomics-Based Care Through Interprofessional Education.
Yee Ming Lee et al. Am J Pharm Educ 2023 87(5) 100007
An Introductory Tutorial on Cardiovascular Pharmacogenetics for Healthcare Providers.
Akinyemi Oni-Orisan et al. Clin Pharmacol Ther 2023
Association of HER2DX with pathological complete response and survival outcomes in HER2-positive breast cancer.
G Villacampa et al. Ann Oncol 2023
Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey.
Kathryn A Mraz et al. Front Oncol 2023 131141810
Economic evaluation of pharmacogenomic-guided antiplatelet treatment in Spanish patients suffering from acute coronary syndrome participating in the U-PGx PREPARE study.
Margarita-Ioanna Koufaki et al. Hum Genomics 2023 17(1) 51
Gene-based drug therapy in children.
S Rod Rassekh et al. Paediatr Child Health 2023 28(4) 205-251
Implementation of pharmacogenetic testing in medication reviews in a hospital setting.
Bodil Jahren Hjemås et al. Br J Clin Pharmacol 2023
Integrating real-world data in cost-effectiveness analysis of universal HLA-B*15:02 screening in Malaysia.
Huey Yi Chong et al. Br J Clin Pharmacol 2023
Treatment of Homozygous Familial Hypercholesterolemia With ANGPTL3 Inhibitor, Evinacumab.
Isabel Shamsudeen et al. JCEM Case Rep 2023 1(3) luad058
Urgent call for guidance supporting gene-based drug dosing in children and adolescents.
Sierra Scodellaro et al. Paediatr Child Health 2023 28(4) 205-245
Efficacy of COVID-19 mRNA vaccination in patients with autoimmune disorders: humoral and cellular immune response.
Filippini Federica, et al. BMC medicine 2023 0 0. (1) 210
Genetic Determinants of the Acute Respiratory Distress Syndrome.
Suarez-Pajes Eva, et al. Journal of clinical medicine 2023 0 0. (11)
An updated examination of the perception of barriers for pharmacogenomics implementation and the usefulness of drug/gene pairs in Latin America and the Caribbean.
Aimeé Salas-Hernández et al. Front Pharmacol 2023 141175737
Evaluation of HLA-B*05, *07, *08, *27 and *51 Allele Expression in Adults with Immune Thrombocytopenic Purpura.
Niloofar Yazdani Rad et al. Maedica (Bucur) 2023 18(1) 61-66
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.
Børge Holen et al. Addict Biol 2023 28(6) e13282
Mental Health Prescribers' Perceptions on the Use of Pharmacogenetic Testing in the Management of Depression in the Middle East and North Africa Region.
Shimaa Aboelbaha et al. Pharmgenomics Pers Med 2023 16503-518
Pharmacogenomics in practice: a review and implementation guide.
Danya Kabbani et al. Front Pharmacol 2023 141189976
The impact of genomic variants on patient response to inhaled bronchodilators: a comprehensive update.
Maria Gabriella Matera et al. Expert Opin Drug Metab Toxicol 2023
Inside the nascent industry of AI-designed drugs.
Carrie Arnold et al. Nat Med 2023 6
A model for the return and referral of all clinically significant secondary findings of genomic sequencing.
Rita Kodida et al. J Med Genet 2023
Addressing barriers to increased adoption of DPYD genotyping at a large multisite cancer center.
Sarah A Morris et al. Am J Health Syst Pharm 2023
Molecular Epidemiology of SARS-CoV-2 Omicron Sub-Lineages Isolated from Turkish Patients Infected with COVID-19.
Sayan Murat, et al. Viruses 2023 0 0. (5)
A randomized controlled trial of analogue pharmacogenomic testing feedback for psychotropic medications.
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Genomic Landscape of Circulating-Tumor DNA in a Diverse Cohort of Metastatic Breast Cancer Patients.
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Ultrasensitive NO Sensor Based on a Nickel Single-Atom Electrocatalyst for Preliminary Screening of COVID-19.
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[Clinical features of children and their family members with family clusters of SARS-CoV-2 Omicron variant infection in Shanghai, China: an analysis of 380 cases].
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Integrative In Silico Investigation Reveals the Host-Virus Interactions in Repurposed Drugs Against SARS-CoV-2.
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A Review: Highlighting the Links between Epigenetics, COVID-19 Infection, and Vitamin D.
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The Multiple Faces of Nitric Oxide in Chronic Granulomatous Disease: A Comprehensive Update.
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Integrating pharmacogenomics into precision pain management.
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PharmaKoVariome database for supporting genetic testing.
Kim Jungeun et al. Database : the journal of biological databases and curation 2022 2022
Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984.
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Do genetics contribute to TNF inhibitor response prediction in Psoriatic Arthritis?
PDK Curry et al, The PGX Journal, October 15, 2022
Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug-Protein Binding.
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Possible Clinical and Pharmacogenetic Predictors of the Efficacy and Safety of Carbamazepine in Post-COVID-19 Depression.
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Cost effectiveness of pharmacogenetic testing for drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines: a systematic review.
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Development and Validation of the Minnesota Assessment of Pharmacogenomic Literacy (MAPL).
Allen Josiah D et al. Journal of personalized medicine 2022 12(9)
Pharmacogenetic Expression of CYP2C19 in a Pediatric Population.
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Treating hereditary transthyretin amyloidosis: Present & future challenges.
Echaniz-Laguna A et al. Revue neurologique 2022
CML-466 Asciminib Provides Durable Molecular Responses in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With the T315I Mutation: Updated Efficacy and Safety Data From a Phase I Trial.
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Cross-GWAS coherence test at the gene and pathway level.
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MPN-024 Hypereosinophilic Syndrome: A Catastrophic Pediatric Case.
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Pharmacogenomics deliberations of 2-deoxy-d-glucose in the treatment of COVID-19 disease: an in silico approach.
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Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19.
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Identification of Suitable Drug Combinations for Treating COVID-19 Using a Novel Machine Learning Approach: The RAIN Method.
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Atypical Hemolytic Uremic Syndrome after SARS-CoV-2 Infection: Report of Two Cases.
Smarz-Widelska Iwona, et al. International journal of environmental research and public health 2022 0 0. (18)
Canakinumab might be Protective against Severe COVID-19 for Patients with Autoinflammatory Disorders.
Alkan Arif, et al. Mediterranean journal of rheumatology 2022 0 0. (2) 237-240
Pharmacogenomic Testing and Depressive Symptom Remission: A Systematic Review and Meta-Analysis of Prospective, Controlled Clinical Trials.
Brown Lisa C et al. Clinical pharmacology and therapeutics 2022
Impact of SARS-CoV-2 vaccination and booster on COVID-19 symptom severity over time in the COVID-OUT trial.
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A comparison of machine learning algorithms in predicting COVID-19 prognostics.
Ustebay Serpil, et al. Internal and emergency medicine 2022 0 0.
A high-throughput lipidomics and transcriptomic approach reveals novel compounds from sugarcane linked with promising therapeutic potential against COVID-19.
Rao Muhammad Junaid, et al. Frontiers in nutrition 2022 0 0. 988249
Discovering common pathogenetic processes between COVID-19 and sepsis by bioinformatics and system biology approach.
Lu Lu, et al. Frontiers in immunology 2022 0 0. 975848
GSK3326595 is a promising drug to prevent SARS-CoV-2 Omicron and other variants infection by inhibiting ACE2-R671 di-methylation.
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Interaction of surface glycoprotein of SARS-CoV-2 variants of concern with potential drug candidates: A molecular docking study.
Mavlankar Anuj, et al. F1000Research 2022 0 0.
Qualitative Subgenomic RNA to Monitor the Response to Remdesivir in Hospitalized Patients with COVID-19: impact on the length of hospital stay and mortality.
Alonso-Navarro Rodrigo, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 0 0.
Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity.
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Predicting the need for mechanical ventilation and mortality in hospitalized COVID-19 patients who received heparin.
Pezoulas Vasileios C, et al. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2022 0 0. 1020-1023
Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19.
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Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection.
Heyer Andreas, et al. Cell reports. Medicine 2022 0 0. 100735
COVID-19 Pharmacotherapy: Drug Development, Repurposing of Drugs, and the Role of Pharmacogenomics.
Bock Rebecca, et al. Methods in molecular biology (Clifton, N.J.) 2022 0 0. 187-199
A DNA-based non-infectious replicon system to study SARS-CoV-2 RNA synthesis.
Feng Xiaolong, et al. Computational and structural biotechnology journal 2022 0 0.
Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants.
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SARS-CoV-2 VOCs, Mutational diversity and clinical outcome: Are they modulating drug efficacy by altered binding strength?
Saifi Sheeba, et al. Genomics 2022 0 0. 110466
Pharmacogenetics of Cardiovascular Prevention in Diabetes: From Precision Medicine to Identification of Novel Targets
ML Morieri et al, J Per Medicine, August 29,2022
Application of Machine Learning in Hospitalized Patients with Severe COVID-19 Treated with Tocilizumab.
Ramón Antonio, et al. Journal of clinical medicine 2022 0 0. (16)
Toxic epidermal necrolysis after first dose of Pfizer-BioNTech (BNT162b2) vaccination with pharmacogenomic testing.
Siripipattanamongkol Nunthana, et al. Pediatric dermatology 2022 0 0. (4) 601-605
Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 Variants.
Neerukonda Sabari Nath, et al. Journal of virology 2022 0 0. e0114022
Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance.
Flisiak Robert, et al. Pharmacological reports : PR 2022 0 0.
IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention.
Blasiak Agata, et al. ACS nano 2022 0 0.
SOCS1 Haploinsufficiency Presenting as Severe Enthesitis, Bone Marrow Hypocellularity, and Refractory Thrombocytopenia in a Pediatric Patient with Subsequent Response to JAK Inhibition.
Michniacki Thomas F, et al. Journal of clinical immunology 2022 0 0.
A Systematic Study on the Optimal Nucleotide Analogue Concentration and Rate Limiting Nucleotide of the SARS-CoV-2 RNA-Dependent RNA Polymerase.
Vatandaslar Hasan, et al. International journal of molecular sciences 2022 0 0. (15)
Vitamin D levels and clinical outcomes of SARS-CoV-2 Omicron subvariant BA.2 in children: A longitudinal cohort study.
Peng Denggao, et al. Frontiers in nutrition 2022 0 0. 960859
Antibody Response in Immunocompromised Patients With Hematologic Cancers Who Received a 3-Dose mRNA-1273 Vaccination Schedule for COVID-19.
Haggenburg Sabine, et al. JAMA oncology 2022 0 0.
SARS-CoV-2 gamma variant and chronic arterial insufficiency due to late arterial thrombosis.
de Godoy Jose Maria Pereira, et al. International journal of health sciences 2022 0 0. (4) 70-72
ATP enhances the error-prone ribonucleotide incorporation by the SARS-CoV-2 RNA polymerase.
Pourfarjam Yasin, et al. Biochemical and biophysical research communications 2022 0 0. 53-59
Differential Impact of SARS-CoV-2 Isolates, Namely, the Wuhan Strain, Delta, and Omicron Variants on Erythropoiesis.
Saito Suguru, et al. Microbiology spectrum 2022 0 0. e0173022
Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids.
Volle Romain, et al. Current research in microbial sciences 2022 0 0. 100158
Virtual screening of Indonesian herbal compounds as COVID-19 supportive therapy: machine learning and pharmacophore modeling approaches.
Erlina Linda, et al. BMC complementary medicine and therapies 2022 0 0. (1) 207
Viral Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Infection in mRNA-Vaccinated Individuals Treated and Not Treated with Nirmatrelvir-Ritonavir
EY Dai et al, MERDRXIV, August 4, 2022
PEDOT:PSS in Solution Form Exhibits Strong Potential in Inhibiting SARS-CoV-2 Infection of the Host Cells by Targeting Viruses and Also the Host Cells.
Hung Jo-Ning, et al. Biomacromolecules 2022 0 0.
Baricitinib in COVID-19: a coming-of-age from artificial intelligence to reducing mortality.
Mehta Puja, et al. Lancet (London, England) 2022 0 0. (10349) 338-339
Identification of SARS-CoV-2 inhibitors through phylogenetics and drug repurposing.
Mishra Anamika, et al. Structural chemistry 2022 0 0. 1-9
A Unique Trinucleotide-Bloc Mutation-Based Two SARS-CoV-2 Genotypes with Potential Pathogenic Impacts.
Ayub Mustak Ibn, et al. Advances in virology 2022 0 0. 5618222
A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants.
Chang Ching-Wen, et al. Viruses 2022 0 0. (7)
Composition of naturally occurring compounds decreases activity of Omicron and SARS-CoV-2 RdRp complex.
Goc Anna, et al. European journal of microbiology & immunology 2022 0 0.
Efficacy of Licensed Monoclonal Antibodies and Antiviral Agents against the SARS-CoV-2 Omicron Sublineages BA.1 and BA.2.
Fiaschi Lia, et al. Viruses 2022 0 0. (7)
Emerging SARS-CoV-2 Mutational Variants of Concern Should Not Vary in Susceptibility to Microbicidal Actives.
Ijaz M Khalid, et al. Life (Basel, Switzerland) 2022 0 0. (7)
Lack of Difference in Tocilizumab Efficacy in the Treatment of Severe COVID-19 Caused by Different SARS-CoV-2 Variants.
Oliynyk Oleksandr, et al. Journal of personalized medicine 2022 0 0. (7)
Clinical Characteristics of COVID-19: Use of Steroids in Mostly Unvaccinated COVID-19 Patients Before the Omicron Variant.
Oh Sang-Min, et al. Journal of Korean medical science 2022 0 0. (29) e228
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether-à-go-go-Related Gene and Cav1.2.
Zheng Zequn, et al. Frontiers in pharmacology 2022 0 0. 889713
Virtual Screening of Repurposed Drugs as Potential Spike Protein Inhibitors of Different SARS-CoV-2 Variants: Molecular Docking Study.
Eweas Ahmad F, et al. Current issues in molecular biology 2022 0 0. (7) 3018-3029
Modeling the Potential Impact of Remdesivir Treatment for Hospitalized Patients with COVID-19 in Saudi Arabia on Healthcare Resource Use and Direct Hospital Costs: A Hypothetical Study.
Ruggeri Matteo, et al. Clinical drug investigation 2022 0 0.
VDR gene polymorphisms are associated with the increased susceptibility to COVID-19 among iranian population: A case-control study.
Jafarpoor Ali, et al. International journal of immunogenetics 2022 0 0.
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon Cherrelle et al. Science (New York, N.Y.) 2022 7 eabq3773
eXtreme Gradient Boosting-based method to classify patients with COVID-19.
Ramón Antonio, et al. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2022 0 0.
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinolone.
Lawal Bashir, et al. Computers in biology and medicine 2022 0 0. 105814
SARS-CoV-2 potential drugs, drug targets, and biomarkers: a viral-host interaction network-based analysis.
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[Patient with Good's syndrome and COVID-19. Report of a clinical case].
Maldonado-Domínguez Edwin Daniel, et al. Revista medica del Instituto Mexicano del Seguro Social 2022 0 0. (4) 474-479
Systems biology models to identify the influence of SARS-CoV-2 infections to the progression of human autoimmune diseases.
Al-Mustanjid Md, et al. Informatics in medicine unlocked 2022 0 0. 101003
Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T).
Jukic Ivana, et al. Case reports in gastroenterology 2022 0 0. (2) 320-325
Hypothesis-Agnostic Network-Based Analysis of Real-World Data Suggests Ondansetron is Associated with Lower COVID-19 Any Cause Mortality.
Miller Gregory M, et al. Drugs - real world outcomes 2022 0 0.
Case Report: Successful Treatment With Monoclonal Antibodies in One APDS Patient With Prolonged SARS-CoV-2 Infection Not Responsive to Previous Lines of Treatment.
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Spotlight
Precision Medicine—Are We There Yet? A Narrative Review of Precision Medicine’s Applicability in Primary Care
W Evans et al, JPM, April 15, 2024 (Posted Apr 15, 2024 2PM)
From the abstract: "Precision medicine (PM) has the potential to transform an individual’s health, moving from population-based disease prevention to more personalised management. There is however a tension between the two, with a real risk that this will exacerbate health inequalities and divert funds and attention from basic healthcare requirements leading to worse health outcomes for many. All areas of medicine should consider how this will affect their practice, with PM now strongly encouraged and supported by government initiatives and research funding. In this review, we discuss examples of PM in current practice and its emerging applications in primary care, such as clinical prediction tools that incorporate genomic markers and pharmacogenomic testing. "
Nucleic acid-based drugs for patients with solid tumours.
Sebastian G Huayamares et al. Nat Rev Clin Oncol 2024 4 (Posted Apr 10, 2024 8AM)
From the abstract: "The treatment of patients with advanced-stage solid tumours typically involves a multimodality approach (including surgery, chemotherapy, radiotherapy, targeted therapy and/or immunotherapy), which is often ultimately ineffective. Nucleic acid-based drugs, either as monotherapies or in combination with standard-of-care therapies, are rapidly emerging as novel treatments capable of generating responses in otherwise refractory tumours. These therapies include those using viral vectors (also referred to as gene therapies), several of which have now been approved by regulatory agencies, and nanoparticles containing mRNAs and a range of other nucleotides. "
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of CYP2C9, HLA-A and HLA-B with anti-epileptic drugs.
Lisanne E N Manson et al. Eur J Hum Genet 2024 4 (Posted Apr 04, 2024 9AM)
From the abstract: "This guideline outlines the gene-drug interaction of CYP2C9 and HLA-B with phenytoin, HLA-A and HLA-B with carbamazepine and HLA-B with oxcarbazepine and lamotrigine. A systematic review was performed and pharmacotherapeutic recommendations were developed. For CYP2C9 intermediate and poor metabolisers, the DPWG recommends lowering the daily dose of phenytoin and adjust based on effect and serum concentration after 7–10 days. For HLA-B*15:02 carriers, the risk of severe cutaneous adverse events associated with phenytoin, carbamazepine, oxcarbazepine, and lamotrigine is strongly increased. For carbamazepine, this risk is also increased in HLA-B*15:11 and HLA-A*31:01 carriers. For HLA-B*15:02, HLA-B*15:11 and HLA-A*31:01 positive patients, the DPWG recommends choosing an alternative anti-epileptic drug. "
DNA test says it can predict opioid addiction risk. Skeptics aren’t so sure.
D Ovalle, Washington Post, March 25, 2024 (Posted Mar 25, 2024 8AM)
From the article: " Using a swab inside the cheek and a sophisticated computer algorithm, a DNA test recently approved by federal regulators promises to assess genetic risk of opioid addiction. The test’s maker says results give doctors and patients a crucial tool when considering use of the very pain pills that ignited the nation’s opioid crisis. Some geneticists and public health experts say the test relies on unsound science."
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Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984.
Kim Joseph W et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022 JCO2102947
Sickle Cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub-Saharan Africa and Beyond.
Egesa Walufu Ivan et al. International journal of pediatrics 2022 20223885979
Use of a supervised machine learning model to predict Oncotype DX risk category in node-positive patients older than 50 years of age.
Williams Austin D et al. Breast cancer research and treatment 2022
Saliva metabolomic profile of COVID-19 patients associates with disease severity.
Saheb Sharif-Askari Narjes, et al. Metabolomics : Official journal of the Metabolomic Society 2022 0 0. (11) 81
The Impact of Elexacaftor/Ivacaftor/Tezacaftor on Cystic Fibrosis Patients Who Acquire COVID-19 Infection.
Miles Brittany, et al. Cureus 2022 0 0. (9) e29276
Unsupervised clustering reveals phenotypes of AKI in ICU COVID-19 patients.
Legouis David, et al. Frontiers in medicine 2022 0 0. 980160
Atypical hemolytic uremic syndrome triggered by mRNA vaccination against SARS-CoV-2: Case report.
Rysava Romana, et al. Frontiers in immunology 2022 0 0. 1001366
Diabetes IN hospital - Glucose and Outcomes in the COVID-19 pandemic (DINGO COVID-19): the 2020 Melbourne hospital experience prior to novel variants and vaccinations.
Barmanray Rahul D, et al. Internal medicine journal 2022 0 0.
Infliximab and tofacitinib attenuate neutralizing antibody responses against SARS-CoV-2 ancestral and Omicron variants in IBD patients following 3 doses of COVID-19 vaccine.
Liu Zhigang, et al. Gastroenterology 2022 0 0.
Machine learning in the diagnosis of asthma phenotypes during coronavirus disease 2019 pandemic.
Gawlewicz-Mroczka Agnieszka, et al. Clinical and translational allergy 2022 0 0. (10) e12201
Considerations into pharmacogenomics of COVID-19 pharmacotherapy: Hope, hype and reality.
Al-Taie Anmar, et al. Pulmonary pharmacology & therapeutics 2022 0 0. 102172
Factors Associated With Severe COVID-19 Among Vaccinated Adults Treated in US Veterans Affairs Hospitals.
Vo Austin D et al. JAMA network open 2022 10 (10) e2240037
Seeking to improve access to COVID-19 therapeutics in the remote Torres and Cape communities of Far North Queensland during the first COVID-19 omicron outbreak.
Galloway Sarah, et al. Rural and remote health 2022 0 0. (4) 7657
Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19: correspondence.
Mungmunpuntipantip Rujittika, et al. Pediatric research 2022 0 0.
Clinical and Genomic Features of HER2 Exon 20 Insertion Mutations and Characterization of HER2 Expression by Immunohistochemistry in East Asian Non-Small-Cell Lung Cancer.
Tan Aaron C et al. JCO precision oncology 2022 6e2200278
Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts.
Nguyen Jenny Q et al. Journal of the American Medical Informatics Association : JAMIA 2022
Designing an evidence based community pharmacy service specification for a pharmacogenomic testing service.
Rendell Tim et al. International journal of clinical pharmacy 2022
Exploring the Efficacy of Alirocumab and Evolocumab in Reducing Low-Density Lipoprotein (LDL) Cholesterol Levels in Patients With Familial Hypercholesterolemia: A Systematic Review.
Luthra Gaurav et al. Cureus 2022 14(9) e28930
Genomic profiling in low grade serous ovarian cancer: Identification of novel markers for disease diagnosis and therapy.
ElNaggar Adam et al. Gynecologic oncology 2022
Implementing comprehensive pharmacogenomics in a community hospital-associated primary care setting.
Wick Jennifer A et al. Journal of the American Pharmacists Association : JAPhA 2022
Pharmacogenomics at the post-pandemic: If not now, then when?
Al-Mahayri Zeina N et al. Frontiers in pharmacology 2022 131013527
The efficacy and tolerability of combining pemetrexed-based chemotherapy with gefitinib in the first-line treatment of non-small cell lung cancer with mutated EGFR: A pooled analysis of randomized clinical trials.
Wang Bi-Cheng et al. PloS one 2022 17(10) e0275919
Characteristics and management of multiple sclerosis patients during the Omicron era: is there a concern about the MS course in the face of the new variant of COVID-19?
Paybast Sepideh, et al. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2022 0 0.
Clinical antiviral efficacy of remdesivir and casirivimab/imdevimab against the SARS-CoV-2 Delta and Omicron variants
P Jittamala et al, MEDRXIV, October 19, 2022
Do genetics contribute to TNF inhibitor response prediction in Psoriatic Arthritis?
PDK Curry et al, The PGX Journal, October 15, 2022
Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug-Protein Binding.
Alamri Mubarak A, et al. Molecules (Basel, Switzerland) 2022 0 0. (19)
Coronavirus Disease 2019-Associated Thrombotic Microangiopathy: Literature Review.
Malgaj Vrecko Marija, et al. International journal of molecular sciences 2022 0 0. (19)
Evaluation of a novel rapid genomic test including polygenic risk scores for the diagnosis and management of familial hypercholesterolaemia.
Neves Emma et al. Global cardiology science & practice 2022 2021(4) e202131
Genome Reporting for Healthy Populations-Pipeline for Genomic Screening from the GENCOV COVID-19 Study.
Frangione Erika et al. Current protocols 2022 2(10) e534
Does ACE2 mediate the detrimental effect of exposures related to COVID-19 risk: A Mendelian randomization investigation.
Yeung Shiu Lun Au, et al. Journal of medical virology 2022 0 0.
A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.
Zhou Yadi, et al. Nature biotechnology 2022 0 0.
Haploidentical CD3+ TCR αβ/CD19+ depleted HSCT for MHC Class II deficiency and persistent SARS-CoV-2 pneumonitis.
Ramanathan Subramaniam, et al. The journal of allergy and clinical immunology. Global 2022 0 0.
Knowledge gaps for prophylactic antithrombotic agents use in patients with COVID-19: Insights on new variants, vaccination and emerging antivirals.
Talasaz Azita Hajhossein, et al. Thrombosis and haemostasis 2022 0 0.
Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation.
Carlson Christopher R, et al. The Journal of biological chemistry 2022 0 0. 102560
Immunogenicity and Safety of the Spikevax® (Moderna) mRNA SARS-CoV-2 Vaccine in Patients with Primary Humoral Immunodeficiency.
Kralickova Pavlina, et al. International archives of allergy and immunology 2022 0 0. 1-14
Early insights from a pharmacogenomic-enriched comprehensive medication management program implementation in an adult employee population.
Keogh Murray et al. Journal of occupational and environmental medicine 2022
Ensuring equity: Pharmacogenetic implementation in rural and tribal communities.
Leitch Tianna M et al. Frontiers in pharmacology 2022 13953142
Pharmacogenetic profiling via genome sequencing in children with medical complexity.
Pan Amy et al. Pediatric research 2022
Pharmacogenomics implementation in cardiovascular disease in a highly diverse population: initial findings and lessons learned from a pilot study in United Arab Emirates.
Al-Mahayri Zeina N et al. Human genomics 2022 16(1) 42
Pharmacogenomics in psychiatry - the challenge of cytochrome P450 enzyme phenoconversion and solutions to assist precision dosing.
Mostafa Sam et al. Pharmacogenomics 2022 0
Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2.
Wagoner Jessica, et al. Microbiology spectrum 2022 0 0. e0333122
Machine learning approach for automated predicting of COVID-19 severity based on clinical and paraclinical characteristics: Serum levels of zinc, calcium, and vitamin D.
Jahangirimehr Azam, et al. Clinical nutrition ESPEN 2022 0 0. 404-411
Rapid selection of sotrovimab escape variants in SARS-CoV-2 Omicron infected immunocompromised patients.
Gliga Smaranda, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 0 0.
Viral load decrease in SARS-CoV-2 BA.1 and BA.2 Omicron sublineages infection after treatment with monoclonal antibodies and direct antiviral agents.
Valentina Mazzotta, et al. Journal of medical virology 2022 0 0.
Racial Disparities in Pulse Oximeter Device Inaccuracy and Estimated Clinical Impact on COVID-19 Treatment Course.
Sudat Sylvia E K et al. American journal of epidemiology 2022 9
Comprehensive analysis of immune responses in CLL patients after heterologous COVID-19 vaccination.
Lee Hye Kyung, et al. medRxiv : the preprint server for health sciences 2022 0 0.
Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach.
Charitou Theodosia, et al. The pharmacogenomics journal 2022 0 0.
Possible Clinical and Pharmacogenetic Predictors of the Efficacy and Safety of Carbamazepine in Post-COVID-19 Depression.
Vaiman Elena, et al. Psychiatria Danubina 2022 0 0. (Suppl 8) 31-37
Cost effectiveness of pharmacogenetic testing for drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines: a systematic review.
Morris Sarah A et al. Clinical pharmacology and therapeutics 2022
Cost-Effectiveness of Pharmacogenomics-Guided Prescribing to Prevent Gene-Drug-Related Deaths: A Decision-Analytic Model.
van der Wouden Cathelijne H et al. Frontiers in pharmacology 2022 13918493
Development and Validation of the Minnesota Assessment of Pharmacogenomic Literacy (MAPL).
Allen Josiah D et al. Journal of personalized medicine 2022 12(9)
Pharmacogenetic Expression of CYP2C19 in a Pediatric Population.
Pierre-François Marie Josette Déborah et al. Journal of personalized medicine 2022 12(9)
Treating hereditary transthyretin amyloidosis: Present & future challenges.
Echaniz-Laguna A et al. Revue neurologique 2022
CML-466 Asciminib Provides Durable Molecular Responses in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With the T315I Mutation: Updated Efficacy and Safety Data From a Phase I Trial.
Hughes Timothy P, et al. Clinical lymphoma, myeloma & leukemia 2022 0 0. S300
Cross-GWAS coherence test at the gene and pathway level.
Krefl Daniel, et al. PLoS computational biology 2022 0 0. (9) e1010517
Human gut microbiota and its metabolites impact immune responses in COVID-19 and its complications.
Nagata Naoyoshi, et al. Gastroenterology 2022 0 0.
MPN-024 Hypereosinophilic Syndrome: A Catastrophic Pediatric Case.
Bello Adriana, et al. Clinical lymphoma, myeloma & leukemia 2022 0 0. S322
Pharmacogenomics deliberations of 2-deoxy-d-glucose in the treatment of COVID-19 disease: an in silico approach.
Prabhu Navya B, et al. 3 Biotech 2022 0 0. (11) 287
Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19.
Posadas-Sánchez Rosalinda, et al. Viruses 2022 0 0. (9)
Identification of Suitable Drug Combinations for Treating COVID-19 Using a Novel Machine Learning Approach: The RAIN Method.
Kiaei Aliakbar, et al. Life (Basel, Switzerland) 2022 0 0. (9)
Atypical Hemolytic Uremic Syndrome after SARS-CoV-2 Infection: Report of Two Cases.
Smarz-Widelska Iwona, et al. International journal of environmental research and public health 2022 0 0. (18)
Canakinumab might be Protective against Severe COVID-19 for Patients with Autoinflammatory Disorders.
Alkan Arif, et al. Mediterranean journal of rheumatology 2022 0 0. (2) 237-240
Pharmacogenomic Testing and Depressive Symptom Remission: A Systematic Review and Meta-Analysis of Prospective, Controlled Clinical Trials.
Brown Lisa C et al. Clinical pharmacology and therapeutics 2022
Impact of SARS-CoV-2 vaccination and booster on COVID-19 symptom severity over time in the COVID-OUT trial.
Boulware David R, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 0 0.
A comparison of machine learning algorithms in predicting COVID-19 prognostics.
Ustebay Serpil, et al. Internal and emergency medicine 2022 0 0.
A high-throughput lipidomics and transcriptomic approach reveals novel compounds from sugarcane linked with promising therapeutic potential against COVID-19.
Rao Muhammad Junaid, et al. Frontiers in nutrition 2022 0 0. 988249
Discovering common pathogenetic processes between COVID-19 and sepsis by bioinformatics and system biology approach.
Lu Lu, et al. Frontiers in immunology 2022 0 0. 975848
GSK3326595 is a promising drug to prevent SARS-CoV-2 Omicron and other variants infection by inhibiting ACE2-R671 di-methylation.
Li Zhongwei, et al. Journal of medical virology 2022 0 0.
Interaction of surface glycoprotein of SARS-CoV-2 variants of concern with potential drug candidates: A molecular docking study.
Mavlankar Anuj, et al. F1000Research 2022 0 0.
Qualitative Subgenomic RNA to Monitor the Response to Remdesivir in Hospitalized Patients with COVID-19: impact on the length of hospital stay and mortality.
Alonso-Navarro Rodrigo, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 0 0.
Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity.
Madariaga-Mazón Abraham, et al. Computational and structural biotechnology journal 2022 0 0.
Predicting the need for mechanical ventilation and mortality in hospitalized COVID-19 patients who received heparin.
Pezoulas Vasileios C, et al. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2022 0 0. 1020-1023
Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19.
Zeidan Nancy M S, et al. Pediatric research 2022 0 0.
Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection.
Heyer Andreas, et al. Cell reports. Medicine 2022 0 0. 100735
COVID-19 Pharmacotherapy: Drug Development, Repurposing of Drugs, and the Role of Pharmacogenomics.
Bock Rebecca, et al. Methods in molecular biology (Clifton, N.J.) 2022 0 0. 187-199
A DNA-based non-infectious replicon system to study SARS-CoV-2 RNA synthesis.
Feng Xiaolong, et al. Computational and structural biotechnology journal 2022 0 0.
Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants.
Gelbach Adrianne L, et al. Frontiers in molecular biosciences 2022 0 0. 912887
SARS-CoV-2 VOCs, Mutational diversity and clinical outcome: Are they modulating drug efficacy by altered binding strength?
Saifi Sheeba, et al. Genomics 2022 0 0. 110466
Pharmacogenetics of Cardiovascular Prevention in Diabetes: From Precision Medicine to Identification of Novel Targets
ML Morieri et al, J Per Medicine, August 29,2022
Application of Machine Learning in Hospitalized Patients with Severe COVID-19 Treated with Tocilizumab.
Ramón Antonio, et al. Journal of clinical medicine 2022 0 0. (16)
Toxic epidermal necrolysis after first dose of Pfizer-BioNTech (BNT162b2) vaccination with pharmacogenomic testing.
Siripipattanamongkol Nunthana, et al. Pediatric dermatology 2022 0 0. (4) 601-605
Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 Variants.
Neerukonda Sabari Nath, et al. Journal of virology 2022 0 0. e0114022
Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance.
Flisiak Robert, et al. Pharmacological reports : PR 2022 0 0.
IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention.
Blasiak Agata, et al. ACS nano 2022 0 0.
SOCS1 Haploinsufficiency Presenting as Severe Enthesitis, Bone Marrow Hypocellularity, and Refractory Thrombocytopenia in a Pediatric Patient with Subsequent Response to JAK Inhibition.
Michniacki Thomas F, et al. Journal of clinical immunology 2022 0 0.
A Systematic Study on the Optimal Nucleotide Analogue Concentration and Rate Limiting Nucleotide of the SARS-CoV-2 RNA-Dependent RNA Polymerase.
Vatandaslar Hasan, et al. International journal of molecular sciences 2022 0 0. (15)
Vitamin D levels and clinical outcomes of SARS-CoV-2 Omicron subvariant BA.2 in children: A longitudinal cohort study.
Peng Denggao, et al. Frontiers in nutrition 2022 0 0. 960859
Antibody Response in Immunocompromised Patients With Hematologic Cancers Who Received a 3-Dose mRNA-1273 Vaccination Schedule for COVID-19.
Haggenburg Sabine, et al. JAMA oncology 2022 0 0.
SARS-CoV-2 gamma variant and chronic arterial insufficiency due to late arterial thrombosis.
de Godoy Jose Maria Pereira, et al. International journal of health sciences 2022 0 0. (4) 70-72
ATP enhances the error-prone ribonucleotide incorporation by the SARS-CoV-2 RNA polymerase.
Pourfarjam Yasin, et al. Biochemical and biophysical research communications 2022 0 0. 53-59
Differential Impact of SARS-CoV-2 Isolates, Namely, the Wuhan Strain, Delta, and Omicron Variants on Erythropoiesis.
Saito Suguru, et al. Microbiology spectrum 2022 0 0. e0173022
Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids.
Volle Romain, et al. Current research in microbial sciences 2022 0 0. 100158
Virtual screening of Indonesian herbal compounds as COVID-19 supportive therapy: machine learning and pharmacophore modeling approaches.
Erlina Linda, et al. BMC complementary medicine and therapies 2022 0 0. (1) 207
Viral Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Infection in mRNA-Vaccinated Individuals Treated and Not Treated with Nirmatrelvir-Ritonavir
EY Dai et al, MERDRXIV, August 4, 2022
PEDOT:PSS in Solution Form Exhibits Strong Potential in Inhibiting SARS-CoV-2 Infection of the Host Cells by Targeting Viruses and Also the Host Cells.
Hung Jo-Ning, et al. Biomacromolecules 2022 0 0.
Baricitinib in COVID-19: a coming-of-age from artificial intelligence to reducing mortality.
Mehta Puja, et al. Lancet (London, England) 2022 0 0. (10349) 338-339
Identification of SARS-CoV-2 inhibitors through phylogenetics and drug repurposing.
Mishra Anamika, et al. Structural chemistry 2022 0 0. 1-9
A Unique Trinucleotide-Bloc Mutation-Based Two SARS-CoV-2 Genotypes with Potential Pathogenic Impacts.
Ayub Mustak Ibn, et al. Advances in virology 2022 0 0. 5618222
A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants.
Chang Ching-Wen, et al. Viruses 2022 0 0. (7)
Composition of naturally occurring compounds decreases activity of Omicron and SARS-CoV-2 RdRp complex.
Goc Anna, et al. European journal of microbiology & immunology 2022 0 0.
Efficacy of Licensed Monoclonal Antibodies and Antiviral Agents against the SARS-CoV-2 Omicron Sublineages BA.1 and BA.2.
Fiaschi Lia, et al. Viruses 2022 0 0. (7)
Emerging SARS-CoV-2 Mutational Variants of Concern Should Not Vary in Susceptibility to Microbicidal Actives.
Ijaz M Khalid, et al. Life (Basel, Switzerland) 2022 0 0. (7)
Lack of Difference in Tocilizumab Efficacy in the Treatment of Severe COVID-19 Caused by Different SARS-CoV-2 Variants.
Oliynyk Oleksandr, et al. Journal of personalized medicine 2022 0 0. (7)
Clinical Characteristics of COVID-19: Use of Steroids in Mostly Unvaccinated COVID-19 Patients Before the Omicron Variant.
Oh Sang-Min, et al. Journal of Korean medical science 2022 0 0. (29) e228
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether-à-go-go-Related Gene and Cav1.2.
Zheng Zequn, et al. Frontiers in pharmacology 2022 0 0. 889713
Virtual Screening of Repurposed Drugs as Potential Spike Protein Inhibitors of Different SARS-CoV-2 Variants: Molecular Docking Study.
Eweas Ahmad F, et al. Current issues in molecular biology 2022 0 0. (7) 3018-3029
Modeling the Potential Impact of Remdesivir Treatment for Hospitalized Patients with COVID-19 in Saudi Arabia on Healthcare Resource Use and Direct Hospital Costs: A Hypothetical Study.
Ruggeri Matteo, et al. Clinical drug investigation 2022 0 0.
VDR gene polymorphisms are associated with the increased susceptibility to COVID-19 among iranian population: A case-control study.
Jafarpoor Ali, et al. International journal of immunogenetics 2022 0 0.
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon Cherrelle et al. Science (New York, N.Y.) 2022 7 eabq3773
eXtreme Gradient Boosting-based method to classify patients with COVID-19.
Ramón Antonio, et al. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2022 0 0.
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinolone.
Lawal Bashir, et al. Computers in biology and medicine 2022 0 0. 105814
SARS-CoV-2 potential drugs, drug targets, and biomarkers: a viral-host interaction network-based analysis.
Samy Asmaa, et al. Scientific reports 2022 0 0. (1) 11934
[Patient with Good's syndrome and COVID-19. Report of a clinical case].
Maldonado-Domínguez Edwin Daniel, et al. Revista medica del Instituto Mexicano del Seguro Social 2022 0 0. (4) 474-479
Systems biology models to identify the influence of SARS-CoV-2 infections to the progression of human autoimmune diseases.
Al-Mustanjid Md, et al. Informatics in medicine unlocked 2022 0 0. 101003
Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T).
Jukic Ivana, et al. Case reports in gastroenterology 2022 0 0. (2) 320-325
Hypothesis-Agnostic Network-Based Analysis of Real-World Data Suggests Ondansetron is Associated with Lower COVID-19 Any Cause Mortality.
Miller Gregory M, et al. Drugs - real world outcomes 2022 0 0.
Case Report: Successful Treatment With Monoclonal Antibodies in One APDS Patient With Prolonged SARS-CoV-2 Infection Not Responsive to Previous Lines of Treatment.
Rivalta Beatrice, et al. Frontiers in immunology 2022 0 0. 891274
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About PGx PHGKB
PGx PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other materials that address the translation of genomic and other precision health discoveries into improved health care and prevention related to medications....more
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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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- Page last updated:Apr 19, 2024
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