• Leptospirosis is a bacterial disease that affects humans and animals
  
• Leptospirosis Risk in Outdoor Activities
  

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• Rapid, actionable diagnosis of urban epidemic leptospirosis using a pathogenic Leptospira lipL32-based real-time PCR assay.
  Riediger Irina N et al. PLoS neglected tropical diseases 2017 Sep (9) e0005940
• An Optimized Method for Quantification of Pathogenic Leptospira in Environmental Water Samples.
  Riediger Irina N et al. PloS one 2016 11(8) e0160523
• What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira.
  Fouts Derrick E et al. PLoS neglected tropical diseases 2016 Feb 10(2) e0004403
• Actionable diagnosis of neuroleptospirosis by next-generation sequencing.
  Wilson Michael R et al. N. Engl. J. Med. 2014 Jun 19. 370(25) 2408-17
• Detection of pathogenic Leptospira spp. through real-time PCR (qPCR) targeting the LipL32 gene.
  Stoddard Robyn Anne et al. Methods Mol. Biol. 2013 943257-66

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• Association of Toll-like receptor 2 Arg753Gln and Toll-like receptor 1 Ile602Ser single-nucleotide polymorphisms with leptospirosis in an argentine population.
  Acta tropica 2015 Jun 146 73-80.
  Cédola Maia, Chiani Yosena, Pretre Gabriela, Alberdi Lucrecia, Vanasco Bibiana, Gómez Ricardo
• Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.
  Human immunology 2009 Nov 70 (11): 915-20.
  Fialho Raquel Nunes, Martins Luís, Pinheiro João Paulo, Bettencourt Bruno Filipe, Couto Ana Rita, Santos Margarida Rodrigues, Peixoto Maria José, Garrett Francisco, Leal João, Tomás Ana Maria, Bruges-Armas Jáco
• Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals.
  Psychiatric genetics 2004 Sep 14 (3): 139-42.
  Theisen Frank M, Hinney Anke, Brömel Torsten, Heinzel-Gutenbrunner Monika, Martin Matthias, Krieg Jürgen-Christian, Remschmidt Helmut, Hebebrand Johann
• HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis.
  Genes and immunity 2004 May 5 (3): 197-202.
  Lingappa J, Kuffner T, Tappero J, Whitworth W, Mize A, Kaiser R, McNicholl J

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• Comparison of Mycobacterium ulcerans (Buruli ulcer) and Leptospira sp. (Leptospirosis) dynamics in urban and rural settings.
  Combe Marine et al. PLoS neglected tropical diseases 2019 Jan (1) e0007074 Combe Marine et al. PLoS neglected tropical diseases 2019 Jan (1) e0007074
• Simplified MLST scheme for direct typing of Leptospira human clinical samples.
  Caimi Karina et al. Pathogens and global health 2018 Jul 1-7 Caimi Karina et al. Pathogens and global health 2018 Jul 1-7
• Characterization of the clonal subpopulation Fiocruz L1-130 of Leptospira interrogans in rats and dogs from Brazil.
  Jaeger Lauren Hubert et al. Journal of medical microbiology 2018 Jul Jaeger Lauren Hubert et al. Journal of medical microbiology 2018 Jul
• Diagnosis of Human Leptospirosis in a Clinical Setting: Real-Time PCR High Resolution Melting Analysis for Detection of Leptospira at the Onset of Disease.
  Esteves Lisa M et al. Scientific reports 2018 Jun (1) 9213 Esteves Lisa M et al. Scientific reports 2018 Jun (1) 9213
• Quantification of pathogenic Leptospira in the soils of a Brazilian urban slum.
  Schneider Andrew G et al. PLoS neglected tropical diseases 2018 Apr (4) e0006415 Schneider Andrew G et al. PLoS neglected tropical diseases 2018 Apr (4) e0006415

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• Leptospirosis
  From NCATS Genetic and Rare Diseases Information Center

The Genetic Testing Registry (GTR®) provides a central location for voluntary submission of genetic test information by providers. The scope includes the test's purpose, methodology, validity, evidence of the test's usefulness, and laboratory contacts and credentials. The overarching goal of the GTR is to advance the public health and research into the genetic basis of health and disease.

• Search the Genetic Testing Registry for "Leptospirosis"

OMIM is a comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and updated daily.

• Search OMIM for "Leptospirosis"

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

• Search PubMed Clinical Queries for "Leptospirosis"

The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including dosing guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships.

• Search PharmGKB for "Leptospirosis"