Somatic loss of the Y chromosome is associated with arsenic exposure among Bangladeshi men.
Demanelis Kathryn et al. International journal of epidemiology 2022 9
Ten percent of genotyped men had LoY in at least 5% of cells and % LoY increased with age. Among men randomly selected for genotyping (n?=?778), higher arsenic in drinking water, arsenic consumed and urinary arsenic were associated with increased % LoY (P?=?0.006, P?=?0.06 and P?=?0.13, respectively). LoY was associated with increased risk of incident skin lesions (P?=?0.008).
Genes influence complex traits through environments that vary between geographic regions
Nature Genetics, September 6, 2022
Migration can increase regional differences in both DNA variants and environmental factors that are associated with socio-economic status. Without controlling for geography, associations between genes and complex traits will therefore include effects of environmental differences between high-income and low-income regions.
From the Genome to the Exposome: Mapping Causal Associations Between Environmental Factors and Population Health
D Rasooly et al, CDC Blog Post, September 6, 2022
Complementary to the “genome,” which is the complete set of an individual’s genetic information, the “exposome” represents an individual’s complete set of environmental exposures throughout their lifetime. Coined in 2005, the “exposome” captures the variable and dynamic environmental exposures from the prenatal period onwards. Factors studied in the exposome extend from social differences and inequalities to behavioral factors such as tobacco smoking and physical activity. Our genome and exposome interact throughout our lives in causing various diseases.
Environmental Justice Index
ATSDR, August 2022
The Environmental Justice Index uses data from the U.S. Census Bureau, the U.S. Environmental Protection Agency, the U.S. Mine Safety and Health Administration, and the U.S. Centers for Disease Control and Prevention to rank the cumulative impacts of environmental injustice on health for every census tract. Census tracts are subdivisions of counties for which the Census collects statistical data. The EJI ranks each tract on 36 environmental, social, and health factors and groups them into three overarching modules and ten different domains.
News and Publications
Delay differential equations for the spatially resolved simulation of epidemics with specific application to COVID-19.
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Overlapping Delta and Omicron Outbreaks: Dynamic Panel Data.
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An ensemble model based on early predictors to forecast COVID-19 health care demand in France.
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'We're kind of like genetic nomads': Parents' experiences of biographical disruption and uncertainty following in/conclusive results from newborn cystic fibrosis screening.
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Association of Lipoprotein (a) in Coronary Artery Disease in Young Individuals.
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The Clinically Actionable Molecular Profile of Early versus Late-Stage Non-Small Cell Lung Cancer, an Individual Age and Sex Propensity-Matched Pair Analysis.
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Development and Evaluation of a Machine Learning Prediction Model for Small-for-Gestational-Age Births in Women Exposed to Radiation before Pregnancy.
Bai Xi et al. Journal of personalized medicine 2022 12(4)
The Utility of Conventional Amino Acid PET Radiotracers in the Evaluation of Glioma Recurrence also in Comparison with MRI.
Santo Giulia et al. Diagnostics (Basel, Switzerland) 2022 12(4)
Training Computers to See the Built Environment Related to Physical Activity: Detection of Microscale Walkability Features Using Computer Vision.
Adams Marc A et al. International journal of environmental research and public health 2022 19(8)
COVID-19 and Chikungunya: an optimal control model with consideration of social and environmental factors.
Hezam Ibrahim M, et al. Journal of ambient intelligence and humanized computing 2022 0 0. 1-18
Use of wastewater surveillance for early detection of Alpha and Epsilon SARS-CoV-2 variants of concern and estimation of overall COVID-19 infection burden.
Vo Van et al. The Science of the total environment 2022 4 155410
COVID-19 Phenotypes and Comorbidity: A Data-Driven, Pattern Recognition Approach Using National Representative Data from the United States.
Vavougios George D, et al. International journal of environmental research and public health 2022 0 0. (8)
eHealth Engagement on Facebook during COVID-19: Simplistic Computational Data Analysis.
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