HuGE Literature Finder
Records 1-30
|
Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2018 May . Chaabane Souhir, Messedi Meriam, Akrout Rim, Ben Hamad Mariem, Turki Mouna, Marzouk Sameh, Keskes Leila, Bahloul Zouheir, Rebai Ahmed, Ayedi Fatma, Maalej Abdellat |
|
MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate.
Genetic testing and molecular biomarkers 2017 Oct . González-Mercado Mirna Gisel, Rivas Fernando, Gallegos-Arreola M Patricia, Morán-Moguel M Cristina, Salazar-Páramo Mario, González-López Laura, Gámez-Nava J Iván, Muñoz-Valle J Francisco, León Ricardo Medina-Coss Y, González-Mercado Anahí, Aceves Mario A, Dávalos Nory O, Macías-Chumacera Agustín, Dávalos Ingrid |
|
MTHFR gene variants and non-MALT lymphoma development in primary Sjogren's syndrome.
Scientific reports 2017 Aug 7 (1): 7354. Fragkioudaki Sofia, Nezos Adrianos, Souliotis Vassilis L, Chatziandreou Ilenia, Saetta Angelica A, Drakoulis Nikolaos, Tzioufas Athanasios G, Voulgarelis Michael, Sfikakis Petros P, Koutsilieris Michael, Crow Mary K, Moutsopoulos Haralampos M, Mavragani Clio |
|
Lack of association between MTHFR A1298C polymorphism and outcome of methotrexate treatment in rheumatoid arthritis patients: evidence from a systematic review and meta-analysis.
International journal of rheumatic diseases 2017 May 20 (5): 526-540. Fan Hongqiong, Li Yanhui, Zhang Li, Li Yuying, Li W |
|
Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
Genetic testing and molecular biomarkers 2017 Mar . Shao Wenjing, Yuan Yi, Li Yuyi |
|
No correlation between MTHFR c.677 C?>?T, MTHFR c.1298 A?>?C, and ABCB1 c.3435 C?>?T polymorphisms and methotrexate therapeutic outcome of rheumatoid arthritis in West Algerian population.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2017 Mar . Boughrara Wefa, Benzaoui Ahmed, Aberkane Meriem, Moghtit Fatima Zohra, Dorgham Samia, Lardjam-Hetraf Aicha Sarah, Ouhaibi-Djellouli Hadjer, Teixeira Elisabeth Petit, Boudjema Abdall |
|
Associations between C677T and A1298C polymorphisms of MTHFR and susceptibility to rheumatoid arthritis: a systematic review and meta-analysis.
Rheumatology international 2017 Feb . Yuan Yi, Shao Wenjing, Li Yuyi |
|
Associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with genetic susceptibility to rheumatoid arthritis: a meta-analysis.
Clinical rheumatology 2017 Feb 36 (2): 287-297. Cen Han, Huang Hua, Zhang Li-Na, Liu Li-Ya, Zhou Li, Xin Xia-Fei, Zhuo Ren-J |
|
Influence MTHFR C677T gene polymorphism in the development of cardiovascular disease in Egyptian patients with rheumatoid arthritis.
Gene 2017 Feb . Abd El-Aziz Tarek A, Mohamed Rasha |
|
The plausible association of MTHFR and ADORA2A polymorphisms with nodules in rheumatoid arthritis patients treated with methotrexate.
Pharmacogenetics and genomics 2016 Nov . Soukup Tomas, Dosedel Martin, Nekvindova Jana, Antonin Kubena Ales, Tacheci Ilja, Duintjer Tebbens Jurjen, Vlcek Jiri, Bradna Petr, Barvik Ivan, Pavek Pe |
|
Methotrexate impact on radiographic progression in biologic-treated rheumatoid arthritis under clinical remission: A case report on monozygotic Caucasian twins.
International journal of immunopathology and pharmacology 2016 Oct . Soukup Tomas, Nekvindova Jana, Dosedel Martin, Brtkova Jindra, Toms Jan, Bastecka Drahomira, Bradna Petr, Vlcek Jiri, Pavek Pe |
|
Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome.
Pharmacogenomics 2016 Sep . Lima Aurea, Bernardes Miguel, Azevedo Rita, Seabra Vitor, Medeiros R |
|
Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis.
Scandinavian journal of rheumatology 2015 Nov 1-7. Dimitroulas T, Sandoo A, Hodson J, Smith J, Douglas K M, Kitas G |
|
Folate metabolic pathway single nucleotide polymorphisms: a predictive pharmacogenetic marker of methotrexate response in Indian (Asian) patients with rheumatoid arthritis.
Pharmacogenomics 2015 Nov . Ghodke-Puranik Yogita, Puranik Amrutesh S, Shintre Pooja, Joshi Kalpana, Patwardhan Bhushan, Lamba Jatinder, Niewold Timothy B, Chopra Arvi |
|
Effect of MTHFR, TGF?1, and TNFB polymorphisms on osteoporosis in rheumatoid arthritis patients.
Gene 2015 Sep 568 (2): 124-8. Saad Mohamed N, Mabrouk Mai S, Eldeib Ayman M, Shaker Olfat |
|
Influence of MTHFR C677T polymorphism on methotrexate monotherapy discontinuation in rheumatoid arthritis patients: results from the GAPAID European project.
Clinical and experimental rheumatology 2015 Aug . Uribarri María, Ruiz-Larrañaga Otsanda, Arteta David, Hernández Lorena, Alcaro Maria Claudia, Martínez Antonio, Escorza-Treviño Sergio, Estonba Andone, Migliorini Paola, Czirják László, Del Amo Jok |
|
The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
Rheumatology international 2015 Jul 35 (7): 1149-61. Soukup Tomas, Dosedel Martin, Pavek Petr, Nekvindova Jana, Barvik Ivan, Bubancova Iva, Bradna Petr, Kubena Ales Antonin, Carazo Alejandro Fernández, Veleta Tomas, Vlcek Ji |
|
Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome.
Gene 2015 Jun 564 (2): 188-92. Inanir Ahmet, Yigit Serbulent, Tekcan Akin, Pinarli Ferda Alpaslan, Inanir Sema, Karakus Nev |
|
Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
European journal of drug metabolism and pharmacokinetics 2015 Jun . Chaabane Souhir, Marzouk Sameh, Akrout Rim, Ben Hamad Mariem, Achour Yosser, Rebai Ahmed, Keskes Leila, Fourati Hela, Bahloul Zouhir, Maalej Abdellat |
|
Methylene tetrahydrofolate reductase genotypes frequencies: association with toxicity and response to methotrexate in rheumatoid arthritis patients.
International journal of clinical pharmacology and therapeutics 2015 Feb 53 (2): 154-62. Saleh Mais M, Irshaid Yacoub M, Mustafa Khader |
|
The effect of IL-4 and MTHFR gene variants in ankylosing spondylitis.
Zeitschrift für Rheumatologie 2015 Feb 74 (1): 60-6. Yigit S, Inanir A, Tural S, Filiz B, Tekcan |
|
Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR , TYMS, and TCII genes and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.
Polskie Archiwum Medycyny Wewn?trznej 2015 125 (3): 152-61. ?wierkot Jerzy, ?l?zak Ryszard, Karpi?ski Pawe?, Paw?owska Justyna, Noga Leszek, Szechi?ski Jacek, Wiland Pio |
|
Genetic Case-Control Study for Eight Polymorphisms Associated with Rheumatoid Arthritis.
PloS one 2015 10 (7): e0131960. Saad Mohamed N, Mabrouk Mai S, Eldeib Ayman M, Shaker Olfat |
|
Association of the MTHFR C677T and A1298C polymorphisms with methotrexate toxicity in rheumatoid arthritis: a meta-analysis.
Clinical rheumatology 2014 Dec 33 (12): 1715-24. Song Gwan Gyu, Bae Sang-Cheol, Lee Young |
|
Impact of MTHFR rs1801133, MTHFR rs1801131 and ABCB1 rs1045642 polymorphisms with increased susceptibility of rheumatoid arthritis in the West Algerian population: A case-control study.
Acta reumatologica portuguesa 2014 Dec . Boughrara Wefa, Aberkane Meriem, Fodil Mostefa, Benzaoui Ahmed, Dorgham Samia, Zemani Faouzia, Dahmani Chahinez, Petit Teixeira Elisabeth, Boudjema Abdell |
|
Polymorphisms in genes involved in the mechanism of action of methotrexate: are they associated with outcome in rheumatoid arthritis patients?
Pharmacogenomics 2014 Jun 15 (8): 1079-90. Salazar Juliana, Moya Patricia, Altés Albert, Díaz-Torné César, Casademont Jordi, Cerdà-Gabaroi Dacia, Corominas Hèctor, Baiget Montserr |
|
MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis.
Pharmacogenomics 2014 Mar 15 (4): 467-75. Morgan Michael D, Al-Shaarawy Nashwa, Martin Steve, Robinson James I, Twigg Sarah, , Magdy Awadalla A, Omar Aziza Sayed, Ghattas Maivel H, Emery Paul, Barrett Jennifer H, Morgan Ann |
|
Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: implication of MTHFR rs1801133 and ATIC rs4673993 polymorphisms.
BioMed research international 2014 2014 368681. Lima Aurea, Monteiro Joaquim, Bernardes Miguel, Sousa Hugo, Azevedo Rita, Seabra Vitor, Medeiros R |
|
Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis.
The Journal of rheumatology 2013 Jun 40 (6): 809-17. Davis Lisa A, Cannon Grant W, Pointer Lauren F, Haverhals Leah M, Wolff Roger K, Mikuls Ted R, Reimold Andreas M, Kerr Gail S, Richards J Steuart, Johnson Dannette S, Valuck Robert, Prochazka Allan, Caplan Lir |
|
IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects.
Immunology letters 2013 May 152 (2): 104-8. Inanir Ahmet, Yigit Serbulent, Tekcan Ak?n, Tural Sengul, Kismali Gork |
|
MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.
The pharmacogenomics journal 2013 Apr 13 (2): 137-47. Owen S A, Lunt M, Bowes J, Hider S L, Bruce I N, Thomson W, Barton |
|
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
Rheumatology international 2012 Dec . Geçene M, Tuncay F, Borman P, Yücel D, Senes M, Y?lmaz BK |
|
Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
Omics : a journal of integrative biology 2012 Nov 16 (11): 589-95. Plaza-Plaza José Cristian, Aguilera Margarita, Cañadas-Garre Marisa, Chemello Clarice, González-Utrilla Alfonso, Faus Dader María José, Calleja Miguel Ang |
|
MTHFR gene C677T mutation and ACE gene I/D polymorphism in Turkish patient with osteoarthritis.
Disease markers 2012 Oct . Inanir A, Yigit S, Tural S, Cecen O, Yildirim E |
|
Methylenetetrahydrofolate reductase polymorphisms, C677T and A1298C, are associated with methotrexate-related toxicities in Korean patients with rheumatoid arthritis.
Rheumatology international 2012 Jun 32 (6): 1837-42. Choe Jung-Yoon, Lee Hwajeong, Jung Hyun-Young, Park Sung-Hoon, Bae Sang-Cheol, Kim Seong-K |
|
The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
Scandinavian journal of rheumatology 2012 Feb 41 (1): 10-4. Cáliz R, del Amo J, Balsa A, Blanco F, Silva L, Sanmarti R, Martínez F G, Collado M D, Ramirez M del Carmen, Tejedor D, Artieda M, Pascual-Salcedo D, Oreiro N, Andreu J L, Graell E, Simon L, Martínez A, Mulero |
|
Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis.
Drug metabolism and pharmacokinetics 2012 27 (2): 192-9. Kato Tomomi, Hamada Akinobu, Mori Shunsuke, Saito Hideyu |
|
MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis.
Disease markers 2012 32 (2): 109-14. Brambila-Tapia Aniel Jessica Leticia, Durán-González Jorge, Sandoval-Ramírez Lucila, Mena Juan Pablo, Salazar-Páramo Mario, Gámez-Nava Jorge Iván, González-López Laura, Lazalde-Medina B Brissia, Dávalos Nory Omayra, Peralta-Leal Valeria, Vázquez del Mercado Mónica, Beltrán-Miranda Claudia Patricia, Dávalos Ingrid Patric |
|
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
Annals of the rheumatic diseases 2011 Aug 70 (8): 1395-400. Hinks Anne, Moncrieffe Halima, Martin Paul, Ursu Simona, Lal Sham, Kassoumeri Laura, Weiler Tracey, Glass David N, Thompson Susan D, Wedderburn Lucy R, Thomson Wen |
|
Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.
The pharmacogenomics journal 2011 Aug 11 (4): 287-91. Mena J P, Salazar-Páramo M, González-López L, Gámez-Nava J I, Sandoval-Ramirez L, Sánchez J D, Figuera L E, Muñoz-Valle F J, Vazquez del Mercado M, Dávalos I |
|
677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
The Journal of rheumatology 2010 Oct 37 (10): 2180-6. Tuková Jana, Chládek Jaroslav, Hroch Milos, Nemcová Dana, Hoza Jozef, Dolezalová Pav |
|
Predictors for remission in rheumatoid arthritis patients: A systematic review.
Arthritis care & research 2010 Aug 62 (8): 1128-43. Katchamart Wanruchada, Johnson Sindhu, Lin Hsing-Ju Lucy, Phumethum Veerapong, Salliot Carine, Bombardier Clai |
|
Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.
Pharmacogenetics and genomics 2010 Jun 20 (6): 367-76. Stamp Lisa K, Chapman Peter T, O'Donnell John L, Zhang Mei, James Jill, Frampton Christopher, Barclay Murray L, Kennedy Martin A, Roberts Rebecca |
|
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.
Arthritis research & therapy 2010 12 (2): R71. Palomino-Morales Rogelio, Gonzalez-Juanatey Carlos, Vazquez-Rodriguez Tomas R, Rodriguez Luis, Miranda-Filloy Jose A, Fernandez-Gutierrez Benjamin, Llorca Javier, Martin Javier, Gonzalez-Gay Miguel |
|
Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis.
Clinical drug investigation 2010 30 (2): 101-8. Lee Young Ho, Song Gwan G |
|
Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis.
Pharmacogenetics and genomics 2009 Dec 19 (12): 935-44. Dervieux Thierry, Wessels Judith A M, van der Straaten Tahar, Penrod Nadia, Moore Jason H, Guchelaar Henk-Jan, Kremer Joel |
|
Optimalization of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A-677C alleles on probability to respond.
Annals of the rheumatic diseases 2009 Aug 68 (8): 1371. Kooloos W M, Wessels J A M, van der Kooij S M, Allaart C F, Huizinga T W J, Guchelaar H |
|
Preliminary study to identify the predictive factors for the response to methotrexate therapy in patients with rheumatoid arthritis.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2009 Jul 129 (7): 843-9. Inoue Sachie, Hashiguchi Masayuki, Takagi Kenji, Kawai Shinichi, Mochizuki Mayu |
|
The effect of 677C>T and 1298A>C MTHFR polymorphisms on sulfasalazine treatment outcome in rheumatoid arthritis.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2009 Jul 42 (7): 660-4. Pawlik A, Kurzawski M, Gawronska-Szklarz B, Gornik W, Dziedziejko V, Safranow K, Juzyszyn Z, Drozdzik |
|
Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis.
Journal of clinical pharmacy and therapeutics 2009 Jun 34 (3): 355-61. Hayashi H, Fujimaki C, Daimon T, Tsuboi S, Matsuyama T, Itoh |
|
Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.
Rheumatology (Oxford, England) 2009 Jun 48 (6): 613-7. Lee Yvonne C, Cui Jing, Costenbader Karen H, Shadick Nancy A, Weinblatt Michael E, Karlson Elizabeth |
|
Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2009 Feb 14 (1): 49-54. Fujimaki Chihiro, Hayashi Hideki, Tsuboi Seiji, Matsuyama Taiji, Kosuge Kazuhiro, Yamada Hiroshi, Inoue Kazuyuki, Itoh Kunihi |
|
Associations between methotrexate treatment and methylenetetrahydrofolate reductase gene polymorphisms with incident fractures in Japanese female rheumatoid arthritis patients.
Journal of bone and mineral metabolism 2009 27 (5): 574-83. Urano Wako, Furuya Takefumi, Inoue Eisuke, Taniguchi Atsuo, Urano Tomohiko, Kotake Shigeru, Sekita Chieko, Inoue Satoshi, Hara Masako, Momohara Shigeki, Kamatani Naoyuki, Yamanaka Hisas |
|
Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.
European journal of clinical pharmacology 2008 Nov 64 (11): 1057-68. Bohanec Grabar Petra, Logar Dusan, Lestan Boris, Dolzan Vi |
|
Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?
Clinical rheumatology 2008 Jun 27 (6): 787-9. Ghodke Yogita, Chopra Arvind, Joshi Kalpana, Patwardhan Bhush |
|
Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.
The Journal of rheumatology 2008 Apr 35 (4): 572-9. Ranganathan Prabha, Culverhouse Robert, Marsh Sharon, Mody Ami, Scott-Horton Tiffany J, Brasington Richard, Joseph Amy, Reddy Virginia, Eisen Seth, McLeod Howard |
|
677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis.
Pharmacogenomics 2007 Nov 8 (11): 1551-9. Kurzawski Mateusz, Pawlik Andrzej, Safranow Krzysztof, Herczynska Magdalena, Drozdzik Mar |
|
Methylenetetrahydrofolate reductase and reduced folate carrier-1 genotypes and methotrexate serum concentrations in patients with rheumatoid arthritis.
The Journal of toxicological sciences 2007 Oct 32 (4): 449-52. Fukino Katsumi, Kawashima Tomoe, Suzuki Masahiko, Ueno Koic |
|
Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
Pharmacogenetics and genomics 2007 Jun 17 (6): 383-90. Taniguchi Atsuo, Urano Wako, Tanaka Eiichi, Furihata Shiori, Kamitsuji Shigeo, Inoue Eisuke, Yamanaka Mariko, Yamanaka Hisashi, Kamatani Naoyu |
|
Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.
The Indian journal of medical research 2006 Nov 124 (5): 521-6. Aggarwal Parshant, Naik Sita, Mishra K P, Aggarwal Amita, Misra Ramna |
|
Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.
Arthritis and rheumatism 2006 Oct 54 (10): 3095-103. Dervieux Thierry, Greenstein Neal, Kremer Jo |
|
Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.
Annals of the rheumatic diseases 2006 Sep 65 (9): 1213-8. Hughes L B, Beasley T M, Patel H, Tiwari H K, Morgan S L, Baggott J E, Saag K G, McNicholl J, Moreland L W, Alarcón G S, Bridges S |
|
Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
The Journal of rheumatology 2006 Jul 33 (7): 1266-74. Kim Seong-Kyu, Jun Jae-Bum, El-Sohemy Ahmed, Bae Sang-Che |
|
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
Arthritis and rheumatism 2006 Apr 54 (4): 1087-95. Wessels Judith A M, de Vries-Bouwstra Jeska K, Heijmans Bas T, Slagboom P Eline, Goekoop-Ruiterman Yvonne P M, Allaart Cornelia F, Kerstens Pit J S M, van Zeben Derkjen, Breedveld Ferdinand C, Dijkmans Ben A C, Huizinga Tom W J, Guchelaar Henk-J |
|
Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.
Arthritis and rheumatism 2006 Feb 54 (2): 607-12. Weisman Michael H, Furst Daniel E, Park Grace S, Kremer Joel M, Smith Katie M, Wallace Daniel J, Caldwell Jacques R, Dervieux Thier |
|
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
The Journal of rheumatology 2005 Sep 32 (9): 1832-6. Schmeling Heinrike, Biber Daniel, Heins Sigrid, Horneff Ge |
|
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
Annals of the rheumatic diseases 2004 Oct 63 (10): 1227-31. Berkun Y, Levartovsky D, Rubinow A, Orbach H, Aamar S, Grenader T, Abou Atta I, Mevorach D, Friedman G, Ben-Yehuda |
|
Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
International journal of molecular medicine 2003 May 11 (5): 593-600. Kumagai Kazuhiko, Hiyama Keiko, Oyama Tetsu, Maeda Hiroyuki, Kohno Nobuo |
|
Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Pharmacogenetics 2002 Apr 12 (3): 183-90. Urano Wako, Taniguchi Atsuo, Yamanaka Hisashi, Tanaka Eiichi, Nakajima Hiroshi, Matsuda Yuko, Akama Hideto, Kitamura Yutaka, Kamatani Naoyu |
|
The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.
Arthritis and rheumatism 2001 Nov 44 (11): 2525-30. van Ede A E, Laan R F, Blom H J, Huizinga T W, Haagsma C J, Giesendorf B A, de Boo T M, van de Putte L |
|
[Methylenetetrahydrofolate reductase polymorphisms in methotrexate treatment of rheumatoid arthritis patients. Review of the literature and personal experience].
Reumatismo 0 61 (2): 98-106. Taraborelli M, Andreoli L, Archetti S, Ferrari M, Cattaneo R, Tincani |
|
677C > T and 1298A > C MTHFR polymorphisms affect arechin treatment outcome in rheumatoid arthritis.
Pharmacological reports : PR 0 59 (6): 721-6. Pawlik Andrzej, Kurzawski Mateusz, Górnik Wanda, Dabrowska-Zamojcin Ewa, Dro?dzik Mar |
|
Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis.
Clinical and experimental rheumatology 0 28 (5): 728-33. Xiao H, Xu J, Zhou X, Stankovich J, Pan F, Zhang Z, Xu S, Lian L, Ding |
|
Decreased expression of methylene tetrahydrofolate reductase (MTHFR) gene in patients with rheumatoid arthritis.
Clinical and experimental rheumatology 0 34 (1): 106-10. Remuzgo-Martínez Sara, Genre Fernanda, López-Mejías Raquel, Ubilla Begoña, Mijares Veronica, Pina Trinitario, Corrales Alfonso, Blanco Ricardo, Martín Javier, Llorca Javier, González-Gay Miguel |
|
Folic acid pathway single nucleotide polymorphisms associated with methotrexate significant adverse events in United States veterans with rheumatoid arthritis.
Clinical and experimental rheumatology 0 32 (3): 324-32. Davis L A, Polk B, Mann A, Wolff R K, Kerr G S, Reimold A M, Cannon G W, Mikuls T R, Caplan |
|
Impact of MTHFR rs1801133, MTHFR rs1801131 and ABCB1 rs1045642 polymorphisms with increased susceptibility of rheumatoid arthritis in the West Algerian population: A case-control study.
Acta reumatologica portuguesa 0 40 (4): 363-371. Boughrara W, Aberkane M, Fodil M, Benzaoui A, Dorgham S, Zemani F, Dahmani C, Petit-Teixeira E, Boudjema |
|
Methylene tetrahydrofolate reductase, transforming growth factor-?1 and lymphotoxin-? genes polymorphisms and susceptibility to rheumatoid arthritis.
Revista brasileira de reumatologia 0 56 (5): 414-420. Shaker Olfat G, Alnoury Amina M, Hegazy Gehan A, El Haddad Hemmat E, Sayed Safaa, Hamdy Ahm |
|
Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
Clinical and experimental rheumatology 0 27 (3): 499-502. Taraborelli M, Andreoli L, Archetti S, Ferrari M, Cattaneo R, Tincani |
|
MTHFR polymorphisms, C677T and A1298C, are not a genetic risk factor for liver stiffness index in methotrexate-treated rheumatoid arthritis patients.
Clinical and experimental rheumatology 0 29 (1): 144-5. Choe Jung-Yoon, Park Sung-Hoon, Kim Seong-K |
- Page last reviewed:Mar 16, 2019
- Page last updated:Jul 29, 2020
- Content source: