A missense single nucleotide polymorphism, V114I of the Werner syndrome gene, is associated with risk of osteoporosis and femoral fracture in the Japanese population.
Journal of bone and mineral metabolism 2015 Jan .
Zhou Heying, Mori Seijiro, Tanaka Masashi, Sawabe Motoji, Arai Tomio, Muramatsu Masaaki, Mieno Makiko Naka, Shinkai Shoji, Yamada Yoshiji, Miyachi Motohiko, Murakami Haruka, Sanada Kiyoshi, Ito Hide
A polymorphic variant at the Werner helicase (WRN) gene is associated with bone density, but not spondylosis, in postmenopausal women.
Journal of bone and mineral metabolism 2001 19 (5): 296-301.
Ogata N, Shiraki M, Hosoi T, Koshizuka Y, Nakamura K, Kawaguchi