HuGE Literature Finder
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Records 1-100
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Genetic variation in the ATP binding cassette transporter ABCC10 is associated with neutropenia for docetaxel in Japanese lung cancer patients cohort.
BMC cancer 2019 Mar 19 (1): 246. Sone Kazuki, Oguri Tetsuya, Uemura Takehiro, Takeuchi Akira, Fukuda Satoshi, Takakuwa Osamu, Maeno Ken, Fukumitsu Kensuke, Kanemitsu Yoshihiro, Ohkubo Hirotsugu, Takemura Masaya, Ito Yutaka, Niimi Ak |
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Influence of UGT1A1 polymorphism on etoposide plus platinum-induced neutropenia in Japanese patients with small-cell lung cancer.
International journal of clinical oncology 2019 Mar 24 (3): 256-261. Negoro Yutaka, Yano Ryoichi, Yoshimura Mari, Suehiro Yoko, Yamashita Shinji, Kodawara Takaaki, Watanabe Kyohei, Tsukamoto Hitoshi, Nakamura Toshiaki, Kadowaki Maiko, Morikawa Miwa, Umeda Yukihiro, Anzai Masaki, Ishizuka Tamotsu, Goto Nobuyu |
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STAT3 mutations in natural killer cells are associated with cytopenia in patients with chronic lymphoproliferative disorder of natural killer cells.
International journal of hematology 2019 Mar . Kawakami Toru, Sekiguchi Nodoka, Kobayashi Jun, Yamane Taku, Nishina Sayaka, Sakai Hitoshi, Hirabayashi Yukio, Nakazawa Hideyuki, Ishida Fumihi |
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Study of gene polymorphisms as predictors of treatment efficacy and toxicity in patients with indolent non-hodgkin lymphomas and mantle cell lymphoma receiving bendamustine and rituximab.
British journal of haematology 2018 Sep . Cencini Emanuele, Sicuranza Anna, Fabbri Alberto, Ferrigno Ilaria, Rigacci Luigi, Cox Maria C, Raspadori Donatella, Bocchia Moni |
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[Relationship between UGT1A1 gene polymorphisms and irinotecan-induced severe adverse events].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2018 Aug 40 (8): 594-599. Wang X F, Ma C, Gong F F, Yi S Y, Xing G C, Wang K J, Yang Q, Cao |
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APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia.
Cancer research and treatment : official journal of Korean Cancer Association 2018 Jul 50 (3): 823-834. Kim Hyery, Seo Heewon, Park Yoomi, Min Byung-Joo, Seo Myung-Eui, Park Kyung Duk, Shin Hee Young, Kim Ju Han, Kang Hyoung J |
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Patient characteristics associated with peglyated interferon alfa-2a induced neutropenia in chronic hepatitis C patients.
Clinical and experimental pharmacology & physiology 2018 Jul 45 (7): 636-642. Hindi Nagham N, Saleh Mohammad |
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Clinical and pharmacogenetic determinants of 5-fluorouracyl/leucovorin/irinotecan toxicity: Results of the PETACC-3 trial.
European journal of cancer (Oxford, England : 1990) 2018 Jun 99 66-77. Tejpar Sabine, Yan Pu, Piessevaux Hubert, Dietrich Daniel, Brauchli Peter, Klingbiel Dirk, Fiocca Roberto, Delorenzi Mauro, Bosman Fred, Roth Arnaud |
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UGT1A1*6 and UGT1A1*28 polymorphisms are correlated with irinotecan-induced toxicity: A meta-analysis.
Asia-Pacific journal of clinical oncology 2018 Jun . Yang Yuwei, Zhou MengMeng, Hu Mingjun, Cui Yanjie, Zhong Qi, Liang Ling, Huang F |
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Relevance of CYP3A4*20, UGT1A1*37 and UGT1A1*28 variants in irinotecan-induced severe toxicity.
British journal of clinical pharmacology 2018 Mar . Riera P, Salazar J, Virgili A, Tobeña M, Sebio A, Gallano P, Barnadas A, Páez |
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ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia.
The pharmacogenomics journal 2018 01 18 (1): 35-42. Li M, Seiser E L, Baldwin R M, Ramirez J, Ratain M J, Innocenti F, Kroetz D |
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Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia.
PloS one 2018 13 (3): e0194400. Charles Bashira A, Hsieh Matthew M, Adeyemo Adebowale A, Shriner Daniel, Ramos Edward, Chin Kyung, Srivastava Kshitij, Zakai Neil A, Cushman Mary, McClure Leslie A, Howard Virginia, Flegel Willy A, Rotimi Charles N, Rodgers Griffin |
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Impact of genetic polymorphisms determining leukocyte/neutrophil count on chemotherapy toxicity.
The pharmacogenomics journal 2018 04 18 (2): 270-274. Glisovic S J, Pastore Y D, Gagne V, Plesa M, Laverdière C, Leclerc J M, Sinnett D, Krajinovic |
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TYMS Gene Polymorphisms in Breast Cancer Patients Receiving 5-Fluorouracil-Based Chemotherapy.
Clinical breast cancer 2018 06 18 (3): e301-e304. Chao Yvonne L, Anders Carey |
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A prospective study of XELIRI plus bevacizumab as a first-line therapy in Japanese patients with unresectable or recurrent colorectal cancer (KSCC1101).
International journal of clinical oncology 2017 Oct 22 (5): 913-920. Ando Koji, Emi Yasunori, Suenaga Toyokuni, Hamanoue Masahiro, Maekawa Soichiro, Sakamoto Yasuo, Kai Seiichiro, Satake Hironaga, Shimose Takayuki, Shimokawa Mototsugu, Saeki Hiroshi, Oki Eiji, Sakai Kenji, Akagi Yoshito, Baba Hideo, Maehara Yoshihiko, |
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Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients.
British journal of cancer 2017 Oct 117 (9): 1269-1277. Ruzzo A, Graziano F, Galli Fabio, Galli Francesca, Rulli E, Lonardi S, Ronzoni M, Massidda B, Zagonel V, Pella N, Mucciarini C, Labianca R, Ionta M T, Bagaloni I, Veltri E, Sozzi P, Barni S, Ricci V, Foltran L, Nicolini M, Biondi E, Bramati A, Turci D, Lazzarelli S, Verusio C, Bergamo F, Sobrero A, Frontini L, Menghi M, Magnani |
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UGT1A1 Gene Polymorphism Predicts Irinotecan-Induced Severe Neutropenia and Diarrhea in Chinese Cancer Patients.
Clinical laboratory 2017 Sep 63 (9): 1339-1346. Peng Hongwei, Duan Zhouping, Pan Decheng, Wen Jinhua, Wei Xiaoh |
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Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
British journal of cancer 2017 Aug . Lévi Francis, Karaboué Abdoulaye, Saffroy Raphaël, Desterke Christophe, Boige Valerie, Smith Denis, Hebbar Mohamed, Innominato Pasquale, Taieb Julien, Carvalho Carlos, Guimbaud Rosine, Focan Christian, Bouchahda Mohamed, Adam René, Ducreux Michel, Milano Gérard, Lemoine Antoinet |
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HLA-G 3'UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer.
International journal of molecular sciences 2017 Jun 18 (7): . Garziera Marica, Virdone Saverio, De Mattia Elena, Scarabel Lucia, Cecchin Erika, Polesel Jerry, D'Andrea Mario, Pella Nicoletta, Buonadonna Angela, Favaretto Adolfo, Toffoli Giusep |
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UGT1A1*6 polymorphisms are correlated with irinotecan-induced neutropenia: a systematic review and meta-analysis.
Cancer chemotherapy and pharmacology 2017 Jun . Zhang Xue, Yin Jia-Fu, Zhang Jiao, Kong Shu-Jia, Zhang Hong-Yin, Chen Xue-M |
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Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab.
Arthritis research & therapy 2017 Mar 19 (1): 44. Ajeganova Sofia, Tesfa Daniel, Hägglund Hans, Fadeel Bengt, Vedin Inger, Zignego Anna Linda, Palmblad J |
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A multi-center phase II study and biomarker analysis of combined cetuximab and modified FOLFIRI as second-line treatment in patients with metastatic gastric cancer.
BMC cancer 2017 03 17 (1): 188. Liu Xin, Guo Weijian, Zhang Wen, Yin Jiliang, Zhang Jun, Zhu Xiaodong, Liu Tianshu, Chen Zhiyu, Wang Biyun, Chang Jianhua, Lv Fangfang, Hong Xiaonan, Wang Huijie, Wang Jialei, Zhao Xinmin, Wu Xianghua, Li J |
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Effects of Shengjiangxiexin decoction on irinotecan-induced toxicity in patients with UGT1A1*28 and UGT1A1*6 polymorphisms.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2017 02 37 (1): 35-42. Deng Bo, Jia Liqun, Tan Huangying, Lou Yanni, Li Xue, Li Yuan, Yu Li |
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[Chinese multicenter randomized trial of customized chemotherapy based on BRCA1 (breast cancer susceptibility gene 1)-RAP80 (receptor-associated protein 80) mRNA expression in advanced non-small cell lung cancer (NSCLC) patients].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2016 Nov 38 (11): 868-873. Wei J, Qian X P, Zou Z Y, Wang L F, Yu L X, You C W, Song Y, Lu H Y, Hu W J, Yan J, Xu X X, Chen X F, Li X Y, Wu Q F, Zhou Y, Zhang F L, Liu B |
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Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study.
Medicine 2016 Nov 95 (44): e5151. Tsuji Daiki, Ikeda Midori, Yamamoto Keisuke, Nakamori Harumi, Kim Yong-Il, Kawasaki Yohei, Otake Aki, Yokoi Mari, Inoue Kazuyuki, Hirai Keita, Nakamichi Hidenori, Tokou Umi, Shiokawa Mitsuru, Itoh Kunihi |
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Molecular psychiatry 2016 Jul . Legge S E, Hamshere M L, Ripke S, Pardinas A F, Goldstein J I, Rees E, Richards A L, Leonenko G, Jorskog L F, , Chambert K D, Collier D A, Genovese G, Giegling I, Holmans P, Jonasdottir A, Kirov G, McCarroll S A, MacCabe J H, Mantripragada K, Moran J L, Neale B M, Stefansson H, Rujescu D, Daly M J, Sullivan P F, Owen M J, O'Donovan M C, Walters J T |
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Cost-effectiveness of screening for DPYD polymorphisms to prevent neutropenia in cancer patients treated with fluoropyrimidines.
Pharmacogenomics 2016 Jun . Cortejoso Lucía, García-González Xandra, García María I, García-Alfonso Pilar, Sanjurjo María, López-Fernández Luis |
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Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project.
Genetic epidemiology 2016 May . Rosenthal Elisabeth A, Makaryan Vahagn, Burt Amber A, Crosslin David R, Kim Daniel Seung, Smith Joshua D, Nickerson Deborah A, Reiner Alex P, Rich Stephen S, Jackson Rebecca D, Ganesh Santhi K, Polfus Linda M, Qi Lihong, Dale David C, , Jarvik Gail |
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Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population.
The pharmacogenomics journal 2016 May . van der Weide K, Loovers H, Pondman K, Bogers J, van der Straaten T, Langemeijer E, Cohen D, Commandeur J, van der Weide |
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Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion.
PLoS genetics 2016 May 12 (5): e1006067. Wu Zuopeng, Liang Rong, Ohnesorg Thomas, Cho Vicky, Lam Wesley, Abhayaratna Walter P, Gatenby Paul A, Perera Chandima, Zhang Yafei, Whittle Belinda, Sinclair Andrew, Goodnow Christopher C, Field Matthew, Andrews T Daniel, Cook Matthew |
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Pharmacokinetics and pharmacogenomics of ?-lactam-induced neutropenia.
Pharmacogenomics 2016 Apr . Hahn Andrea, Fukuda Tsuyoshi, Hahn David, Mizuno Tomoyuki, Frenck Robert W, Vinks Alexander |
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Role of CSF3R mutations in the pathomechanism of congenital neutropenia and secondary acute myeloid leukemia.
Annals of the New York Academy of Sciences 2016 Apr 1370 (1): 119-25. Klimiankou Maksim, Mellor-Heineke Sabine, Zeidler Cornelia, Welte Karl, Skokowa Jul |
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Effects of UGT1A1*6, UGT1A1*28, and ABCB1-3435C>T polymorphisms on irinotecaninduced toxicity in Chinese cancer patients.
International journal of clinical pharmacology and therapeutics 2016 Feb . Yan Liang, Wang Xiao-Fei, Wei Lu-Man, Nie Ya-Li, Liu Jing-Yang, Zhang Li-Ro |
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XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation.
Oncotarget 2016 Feb . Lopes-Aguiar Leisa, Costa Ericka Francislaine Dias, Nogueira Guilherme Augusto Silva, Lima Tathiane Regine Penna, Visacri Marília Berlofa, Pincinato Eder Carvalho, Calonga Luciane, Mariano Fernanda Viviane, Altemani Albina Messias de Almeida Milani, Altemani João Maurício Carrasco, Coutinho-Camillo Cláudia Malheiros, Alves Maria Almerinda Vieira Fernandes Ribeiro, Moriel Patrícia, Ramos Celso Dario, Chone Carlos Takahiro, Lima Carmen Silvia Pass |
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The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.
PloS one 2016 11 (7): e0158984. Dorling Leila, Kar Siddhartha, Michailidou Kyriaki, Hiller Louise, Vallier Anne-Laure, Ingle Susan, Hardy Richard, Bowden Sarah J, Dunn Janet A, Twelves Chris, Poole Christopher J, Caldas Carlos, Earl Helena M, Pharoah Paul D P, Abraham Jean |
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Correlation of UGT1A1(*)28 and (*)6 polymorphisms with irinotecan-induced neutropenia in Thai colorectal cancer patients.
Drug metabolism and pharmacokinetics 2015 Dec . Atasilp Chalirmporn, Chansriwong Pichai, Sirachainan Ekapob, Reungwetwattana Thanyanan, Chamnanphon Montri, Puangpetch Apichaya, Wongwaisayawan Sansanee, Sukasem Chonlaph |
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UDP-glucuronosyltransferase 1A1*6 and *28 polymorphisms as indicators of initial dose level of irinotecan to reduce risk of neutropenia in patients receiving FOLFIRI for colorectal cancer.
International journal of clinical oncology 2015 Dec . Miyata Yoshinori, Touyama Tetsuo, Kusumi Takaya, Morita Yoshitaka, Mizunuma Nobuyuki, Taniguchi Fumihiro, Manabe Mitsua |
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[Relation of MBL ExonI 54 and NF?B1-94ins/del ATTG Polymorphism with Fever during Neutropenia in Patients with Acute Leukaemia after Chemotherapy].
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2015 Oct 23 (5): 1258-64. Xu Wen-Ning, Jiang Zu-Jun, Li Yong-Hua, Xiao Hao-Wen, Gao Yang, Pang Yan, Ouyang Lin, Liu Zeng-Hui, Zhang Le-Qing, Wang Yang, Xiao Ya |
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Polymorphisms within beta-catenin encoding gene affect multiple myeloma development and treatment.
Leukemia research 2015 Oct . Butrym Aleksandra, Rybka Justyna, ?acina Piotr, G?bura Katarzyna, Frontkiewicz Diana, Bogunia-Kubik Katarzyna, Mazur Grzego |
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ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.
Pharmacogenetics and genomics 2015 Sep . Chen Sylvia, Villeneuve Lyne, Jonker Derek, Couture Félix, Laverdière Isabelle, Cecchin Erica, Innocenti Federico, Toffoli Giuseppe, Lévesque Eric, Guillemette Chant |
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Correlation between 'ACKR1/DARC null' polymorphism and benign neutropenia in Yemenite Jews.
British journal of haematology 2015 Sep 170 (6): 892-5. Rappoport Naama, Simon Amos J, Lev Atar, Yacobi Michal, Kaplinsky Chaim, Weingarten Michael, Somech Raz, Amariglio Ninette, Rechavi Gide |
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Role of genetic variation in docetaxel-induced neutropenia and pharmacokinetics.
The pharmacogenomics journal 2015 Sep . Nieuweboer A J M, Smid M, de Graan A-J M, Elbouazzaoui S, de Bruijn P, Eskens F A L M, Hamberg P, Martens J W M, Sparreboom A, de Wit R, van Schaik R H N, Mathijssen R H |
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Using whole exome sequencing to identify genetic markers for carboplatin and gemcitabine-induced toxicities.
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Sep . Green Henrik, Hasmats Johanna, Kupershmidt Ilya, Edsgard Daniel, de Petris Luigi, Lewensohn Rolf, Blackhall Fiona H, Vikingsson Svante, Besse Benjamin, Lindgren Andrea, Koyi Hirsh, Branden Eva, Peterson Curt, Lundeberg Joak |
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Expanding the role of the splicing USB1 gene from Poikiloderma with Neutropenia to acquired myeloid neoplasms.
British journal of haematology 2015 Aug . Negri Gloria, Crescenzi Barbara, Colombo Elisa Adele, Fontana Laura, Barba Gianluca, Arcioni Francesco, Gervasini Cristina, Mecucci Cristina, Larizza Lid |
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Phase II clinical trial of metronomic chemotherapy with combined irinotecan and tegafur-gimeracil-oteracil potassium in metastatic and recurrent breast cancer.
Breast cancer (Tokyo, Japan) 2015 Jul 22 (4): 335-42. Otsuka Hiroko, Fujii Teruhiko, Toh Uhi, Iwakuma Nobutaka, Takahashi Ryuji, Mishima Mai, Takenaka Miki, Kakuma Tatsuyuki, Tanaka Maki, Shirouzu Kaz |
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Stem cell transplantation in severe congenital neutropenia: an analysis from the European Society for Blood and Marrow Transplantation.
Blood 2015 Jul . Fioredda Francesca, Iacobelli Simona, van Biezen Anja, Gaspar Bobby, Ancliff Phil, Donadieu Jean, Aljurf Mahmoud, Peters Christina, Calvillo Michaela, Matthes-Martin Susanne, Morreale Giuseppe, van 't Veer-Tazelaar Nelleke, de Wreede Liesbeth, Al Seraihy Amal, Yesilipek Akif, Fisher Alain, Bierings Marc, Ozturk Gulyuz, Smith Owen, Veys Paul, Ljungman Per, Peffault Delatour Regis, de Toledo Codina José Sánchez, Or Reuven, Ganser Arnold, Afanasyev Boris, Wynn Robert, Kalwak Krzysztof, Marsh Judith, Dufour Car |
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[Examination of UGT1A1 polymorphisms and irinotecan-induced neutropenia in patients with Colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2015 May 42 (5): 585-9. Teruya Tsuyoshi, Nakachi Atsushi, Shimabukuro Nobuhiro, Toritsuka Daisuke, Azuma Yasuharu, Hanashiro Kiyotoshi, Nishiki Takehiro, Ota Morihito, Shimabuku Masamori, Shiroma Hiros |
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Human neutrophil antigen profiles in Banjar, Bugis, Champa, Jawa and Kelantan Malays in Peninsular Malaysia.
Blood transfusion = Trasfusione del sangue 2015 Apr 1-6. Manaf Siti M, Nurwaliyuddin Hanis Z A, Panneerchelvam Sundararajulu, Zafarina Zainuddin, Norazmi Mohd N, Chambers Geoffrey K, Edinur Hisham |
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Relationship between ABCB1 gene polymorphisms and severe neutropenia in patients with breast cancer treated with doxorubicin/cyclophosphamide chemotherapy.
Drug metabolism and pharmacokinetics 2015 Apr 30 (2): 149-53. Ikeda Midori, Tsuji Daiki, Yamamoto Keisuke, Kim Yong-Il, Daimon Takashi, Iwabe Yutaro, Hatori Masahiro, Makuta Ryo, Hayashi Hideki, Inoue Kazuyuki, Nakamichi Hidenori, Shiokawa Mitsuru, Itoh Kunihi |
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A novel UGT1 marker associated with better tolerance against irinotecan-induced severe neutropenia in metastatic colorectal cancer patients.
The pharmacogenomics journal 2015 Mar . Chen S, Laverdiere I, Tourancheau A, Jonker D, Couture F, Cecchin E, Villeneuve L, Harvey M, Court M H, Innocenti F, Toffoli G, Lévesque E, Guillemette |
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Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C.
Human genetics 2015 Mar 134 (3): 279-89. Iio Etsuko, Matsuura Kentaro, Nishida Nao, Maekawa Shinya, Enomoto Nobuyuki, Nakagawa Mina, Sakamoto Naoya, Yatsuhashi Hiroshi, Kurosaki Masayuki, Izumi Namiki, Hiasa Yoichi, Masaki Naohiko, Ide Tatsuya, Hino Keisuke, Tamori Akihiro, Honda Masao, Kaneko Shuichi, Mochida Satoshi, Nomura Hideyuki, Nishiguchi Shuhei, Okuse Chiaki, Itoh Yoshito, Yoshiji Hitoshi, Sakaida Isao, Yamamoto Kazuhide, Watanabe Hisayoshi, Hige Shuhei, Matsumoto Akihiro, Tanaka Eiji, Tokunaga Katsushi, Tanaka Yasuhi |
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The impact of glutathione S-transferase genotype and phenotype on the adverse drug reactions to azathioprine in patients with inflammatory bowel diseases.
Journal of pharmacological sciences 2015 Mar . Liu Hui, Ding Liang, Zhang Fangbin, Zhang Yu, Gao Xiang, Hu Pinjin, Bi Huichang, Huang M |
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[Association of UGT1A1 (*28, *60 and * 93) polymorphism with the adverse reactions of irinotecan chemotherapy in extensive stage small cell lung cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2015 Jan 37 (1): 29-32. Ma Lixia, Chen Yan, Yang Changliang, Jiang Hui, Zhu Jing, Cheng Yi |
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Relationship between UGT1A1*6/*28 polymorphisms and severe toxicities in Chinese patients with pancreatic or biliary tract cancer treated with irinotecan-containing regimens.
Drug design, development and therapy 2015 9 3677-83. Yang Chen, Liu Ying, Xi Wen-qi, Zhou Chen-fei, Jiang Jin-ling, Ma Tao, Ye Zheng-bao, Zhang Jun, Zhu Zheng-ga |
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Prevalence and impact of colony stimulating factor 3 receptor (CSF3R) mutations among Egyptian acute myeloid leukemia patients.
Leukemia research 2014 Jun 38 (6): 722-5. Aref Salah, El-Ghonemy Mohamed, Abouzeid Tarek, El-Sabbagh Amr, El-Baiomy Moham |
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Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits.
Nature genetics 2014 Jun 46 (6): 629-34. Auer Paul L, Teumer Alexander, Schick Ursula, O'Shaughnessy Andrew, Lo Ken Sin, Chami Nathalie, Carlson Chris, de Denus Simon, Dubé Marie-Pierre, Haessler Jeff, Jackson Rebecca D, Kooperberg Charles, Perreault Louis-Philippe Lemieux, Nauck Matthias, Peters Ulrike, Rioux John D, Schmidt Frank, Turcot Valérie, Völker Uwe, Völzke Henry, Greinacher Andreas, Hsu Li, Tardif Jean-Claude, Diaz George A, Reiner Alexander P, Lettre Guillau |
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Pharmacokinetics, safety, and efficacy of FOLFIRI plus bevacizumab in Japanese colorectal cancer patients with UGT1A1 gene polymorphisms.
Journal of clinical pharmacology 2014 May 54 (5): 495-502. Suenaga Mitsukuni, Fuse Nozomu, Yamaguchi Tatsuro, Yamanaka Yasuhiro, Motomura Shigeki, Matsumoto Hiroshi, Hamamoto Yasuo, Mizunuma Nobuyuki, Doi Toshihiko, Hatake Kiyohiko, Iwasaki Junko, Ohtsu Atsus |
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Associations between UGT1A1*6 or UGT1A1*6/*28 polymorphisms and irinotecan-induced neutropenia in Asian cancer patients.
Cancer chemotherapy and pharmacology 2014 Apr 73 (4): 779-88. Han Fei-fei, Guo Chang-long, Yu Dan, Zhu Jin, Gong Li-li, Li Guang-run, Lv Ya-li, Liu He, An Guang-yu, Liu Li-ho |
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Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.
Blood 2014 Apr 123 (14): 2229-37. Skokowa Julia, Steinemann Doris, Katsman-Kuipers Jenny E, Zeidler Cornelia, Klimenkova Olga, Klimiankou Maksim, Unalan Murat, Kandabarau Siarhei, Makaryan Vahagn, Beekman Renee, Behrens Kira, Stocking Carol, Obenauer Julia, Schnittger Susanne, Kohlmann Alexander, Valkhof Marijke G, Hoogenboezem Remco, Göhring Gudrun, Reinhardt Dirk, Schlegelberger Brigitte, Stanulla Martin, Vandenberghe Peter, Donadieu Jean, Zwaan C Michel, Touw Ivo P, van den Heuvel-Eibrink Marry M, Dale David C, Welte Ka |
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Usefulness of one-point plasma SN-38G/SN-38 concentration ratios as a substitute for UGT1A1 genetic information after irinotecan administration.
International journal of clinical oncology 2014 Apr 19 (2): 397-402. Hirose Kouichi, Yamashita Koushiro, Takada Hirofumi, Kaneda Noriko, Fukami Kohei, Maruo Eiji, Kitamura Mizuho, Hasegawa Junichi, Maeda Yorino |
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A single nucleotide polymorphism on the GALNT14 gene as an effective predictor of response to chemotherapy in advanced hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2014 Mar 134 (5): 1214-24. Yeh Chau-Ting, Liang Kung-Hao, Lin Chen-Chun, Chang Ming-Ling, Hsu Cheng-Lung, Hung Chien- |
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The association of UGT1A1*6 and UGT1A1*28 with irinotecan-induced neutropenia in Asians: a meta-analysis.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2014 Feb 19 (1): 56-62. Chen Yi-Jing, Hu Fei, Li Chun-Yan, Fang Jue-Min, Chu Li, Zhang Xi, Xu Qi |
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Prevalence of TPMT polymorphism in Indian patients requiring immunomodulator therapy and its clinical significance.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2014 Jan 33 (1): 41-5. Davavala Sandeep Kirit, Desai Devendra C, Abraham Philip, Ashavaid Tester, Joshi Anand, Gupta Tar |
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ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases.
PloS one 2014 9 (1): e85362. Damaj Gandhi, Joris Magalie, Chandesris Olivia, Hanssens Katia, Soucie Erinn, Canioni Danielle, Kolb Brigitte, Durieu Isabelle, Gyan Emanuel, Livideanu Cristina, Chèze Stephane, Diouf Momar, Garidi Reda, Georgin-Lavialle Sophie, Asnafi Vahid, Lhermitte Ludovic, Lavigne Christian, Launay David, Arock Michel, Lortholary Olivier, Dubreuil Patrice, Hermine Olivi |
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Clinical observations on associations between the UGT1A1 genotype and severe toxicity of irinotecan.
Asian Pacific journal of cancer prevention : APJCP 2014 15 (7): 3335-41. Lu Yan-Yan, Huang Xin-En, Wu Xue-Yan, Cao Jie, Liu Jin, Wang Lin, Xiang J |
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Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients.
Scientific reports 2014 4 6828. Ruzzo Annamaria, Graziano Francesco, Galli Fabio, Giacomini Elisa, Floriani Irene, Galli Francesca, Rulli Eliana, Lonardi Sara, Ronzoni Monica, Massidda Bruno, Zagonel Vittorina, Pella Nicoletta, Mucciarini Claudia, Labianca Roberto, Ionta Maria Teresa, Veltri Enzo, Sozzi Pietro, Barni Sandro, Ricci Vincenzo, Foltran Luisa, Nicolini Mario, Biondi Edoardo, Bramati Annalisa, Turci Daniele, Lazzarelli Silvia, Verusio Claudio, Bergamo Francesca, Sobrero Alberto, Frontini Luciano, Magnani Mau |
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Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer.
Pharmacogenomics 2014 15 (12): 1565-74. Lamba Jatinder Kaur, Fridley Brooke L, Ghosh Taraswi M, Yu Qing, Mehta Gaurav, Gupta Pank |
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MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.
Oncology research and treatment 2014 37 (4): 176-80. Wang Xu, Wang Yi-Zhuo, Ma Ke-Wei, Chen Xiao, Li W |
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UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan.
Cancer science 2013 Dec 104 (12): 1662-9. Hazama Shoichi, Mishima Hideyuki, Tsunedomi Ryouichi, Okuyama Yusuke, Kato Takeshi, Takahashi Ken-ichi, Nozawa Hiroshi, Ando Hideaki, Kobayashi Michiya, Takemoto Hiroyoshi, Nagata Naoki, Kanekiyo Shinsuke, Inoue Yuka, Hamamoto Yoshihiko, Fujita Yusuke, Hinoda Yuji, Okayama Naoko, Oba Koji, Sakamoto Jun-ichi, Oka Masaa |
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Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer.
Cancer chemotherapy and pharmacology 2013 Nov 72 (5): 953-64. Park Sook Ryun, Hong Yong Sang, Lim Hyeong-Seok, Seong Moon-Woo, Kong Sun-Young, Kim Sun Young, Park Young-Iee, Jung Kyung H |
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A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer.
The pharmacogenomics journal 2013 Oct 13 (5): 417-22. Han J-Y, Shin E S, Lee Y-S, Ghang H Y, Kim S-Y, Hwang J-A, Kim J Y, Lee J |
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Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Cancer science 2013 Aug 104 (8): 1074-82. Low Siew-Kee, Chung Suyoun, Takahashi Atsushi, Zembutsu Hitoshi, Mushiroda Taisei, Kubo Michiaki, Nakamura Yusu |
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Impact of NOD2 polymorphisms on infectious complications following chemotherapy in patients with acute myeloid leukaemia.
Annals of hematology 2013 Aug 92 (8): 1071-7. Yomade Olaposi, Spies-Weisshart Bärbel, Glaser Anita, Schnetzke Ulf, Hochhaus Andreas, Scholl Sebasti |
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Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.
The Journal of pharmacology and experimental therapeutics 2013 Apr 345 (1): 95-101. Lévesque Eric, Bélanger Anne-Sophie, Harvey Mario, Couture Félix, Jonker Derek, Innocenti Federico, Cecchin Erica, Toffoli Giuseppe, Guillemette Chant |
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VCP gene variation predicts outcome of advanced non-small-cell lung cancer platinum-based chemotherapy.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Apr 34 (2): 953-61. Peng J, Yang L X, Zhao X Y, Gao Z Q, Yang J, Wu W T, Wang H J, Wang J C, Qian J, Chen H Y, Jin L, Bai C X, Han B H, Wang W M, Lu D |
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Role of pharmacogenetics on adjuvant chemotherapy-induced neutropenia in Chinese breast cancer patients.
Journal of cancer research and clinical oncology 2013 Mar 139 (3): 419-27. Tang Nelson L S, Liao Chen Di, Wang Xingyan, Mo Frankie K F, Chan Vicky T C, Ng Rita, Pang Elizabeth, Suen Joyce J S, Woo Jean, Yeo Winn |
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Interleukin-1 receptor antagonist gene polymorphism increases susceptibility to septic shock in children with acute lymphoblastic leukemia.
The Pediatric infectious disease journal 2013 Feb 32 (2): 136-9. Zapata-Tarrés Marta, Arredondo-García Jose Luis, Rivera-Luna Roberto, Klünder-Klünder Miguel, Mancilla-Ramírez Javier, Sánchez-Urbina Rocío, Vázquez-Cruz Margarita Yolanda, Juárez-Villegas Luis Enrique, Palomo-Colli Miguel Ang |
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A randomized phase II study of gemcitabine and carboplatin with or without cediranib as first-line therapy in advanced non-small-cell lung cancer: North Central Cancer Treatment Group Study N0528.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 Jan 8 (1): 79-88. Dy Grace K, Mandrekar Sumithra J, Nelson Garth D, Meyers Jeffrey P, Adjei Araba A, Ross Helen J, Ansari Rafat H, Lyss Alan P, Stella Philip J, Schild Steven E, Molina Julian R, Adjei Alex |
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The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Pharmacogenetics and genomics 2013 Jan 23 (1): 29-33. Lewis Lionel D, Miller Antonius A, Owzar Kouros, Bies Robert R, Markova Svetlana, Jiang Chen, Kroetz Deanna L, Egorin Merrill J, McLeod Howard L, Ratain Mark J, |
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Polymorphisms of the UDP-glucuronosyl transferase 1A genes are associated with adverse events in cancer patients receiving irinotecan-based chemotherapy.
The Tohoku journal of experimental medicine 2013 229 (2): 107-14. Inoue Kazuyuki, Sonobe Momoyo, Kawamura Yukinori, Etoh Takashi, Takagi Masakazu, Matsumura Takashi, Kikuyama Masataka, Kimura Midori, Minami Sato, Utsuki Hiroaki, Yamazaki Tomoaki, Suzuki Takayo, Tsuji Daiki, Hayashi Hideki, Itoh Kunihi |
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STAT3 mutations are frequent in T-cell large granular lymphocytic leukemia with pure red cell aplasia.
Journal of hematology & oncology 2013 6 (1): 82. Qiu Zhi-Yuan, Fan Lei, Wang Li, Qiao Chun, Wu Yu-Jie, Zhou Jian-Feng, Xu Wei, Li Jian-Yo |
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The influence of BRCA1/BRCA2 mutations on toxicity related to chemotherapy and radiotherapy in early breast cancer patients.
Oncology 2013 85 (5): 278-82. Huszno Joanna, Budryk Magdalena, Ko?osza Zofia, Nowara El?bie |
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UGT1A1 6/28 polymorphisms could predict irinotecan-induced severe neutropenia not diarrhea in Chinese colorectal cancer patients.
Medical oncology (Northwood, London, England) 2013 30 (3): 604. Gao Jing, Zhou Jun, Li Yanyan, Lu Ming, Jia Ru, Shen L |
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Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma.
Internal medicine journal 2012 Oct 42 (10): 1113-9. Keane C, Nourse J P, Crooks P, Nguyen-Van D, Mutsando H, Mollee P, Lea R A, Gandhi M |
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Mannose-binding Lectin Genotype Influences Frequency and Duration of Infectious Complications in Children With Malignancy.
Journal of pediatric hematology/oncology 2012 Oct . Dommett R, Chisholm J, Turner M, Bajaj-Elliott M, Klein NJ |
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High incidence of severe neutropenia after gemcitabine-based chemotherapy in Chinese cancer patients with CDA 79A>C mutation.
Clinica chimica acta; international journal of clinical chemistry 2012 Aug 413 (15-16): 1284-7. Xu Jialin, Zhou Yuhong, Zhang Jing, Chen Yuancheng, Zhuang Rongyuan, Liu Tianshu, Cai Weim |
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An SNP in CYP39A1 is associated with severe neutropenia induced by docetaxel.
Cancer chemotherapy and pharmacology 2012 Jun 69 (6): 1617-24. Uchiyama Toshitaka, Kanno Hitoshi, Ishitani Ken, Fujii Hisaichi, Ohta Hiroaki, Matsui Hideo, Kamatani Naoyuki, Saito Kayo |
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Impact of the UGT1A1*28 allele on response to irinotecan: a systematic review and meta-analysis.
Pharmacogenomics 2012 Jun 13 (8): 889-99. Dias Mafalda M, McKinnon Ross A, Sorich Michael |
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DNA repair gene XPD and XRCC1 polymorphisms and the risk of febrile neutropenia and mucositis in children with leukemia and lymphoma.
Leukemia research 2012 May 36 (5): 565-9. Ozdemir Nihal, Celkan Tiraje, Bar?? Safa, Batar Bahad?r, Güven Mehm |
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Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherapy.
Cancer chemotherapy and pharmacology 2012 May 69 (5): 1221-7. Kim Kyu-pyo, Ahn Jin-Hee, Kim Sung-Bae, Jung Kyung Hae, Yoon Dok Hyun, Lee Jung Shin, Ahn Sei-Hy |
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Pharmacogenetics and genomics 2012 Apr 22 (4): 229-35. Kiyotani Kazuma, Uno Satoko, Mushiroda Taisei, Takahashi Atsushi, Kubo Michiaki, Mitsuhata Naoki, Ina Shinomi, Kihara Chikashi, Kimura Yasutoshi, Yamaue Hiroki, Hirata Koichi, Nakamura Yusuke, Zembutsu Hitos |
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Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.
Journal of hepatology 2012 Feb 56 (2): 313-9. Thompson Alexander J, Clark Paul J, Singh Abanish, Ge Dongliang, Fellay Jacques, Zhu Mingfu, Zhu Qianqian, Urban Thomas J, Patel Keyur, Tillmann Hans L, Naggie Susanna, Afdhal Nezam H, Jacobson Ira M, Esteban Rafael, Poordad Fred, Lawitz Eric J, McCone Jonathan, Shiffman Mitchell L, Galler Greg W, King John W, Kwo Paul Y, Shianna Kevin V, Noviello Stephanie, Pedicone Lisa D, Brass Clifford A, Albrecht Janice K, Sulkowski Mark S, Goldstein David B, McHutchison John G, Muir Andrew |
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[Examination of factors affecting adverse reactions and dosage reduction in UGT1A1 genotyped patients: a retrospective survey of irinotecan].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2012 132 (2): 231-6. Okazaki Keinosuke, Watanabe Toru, Saito Isao, Murayama Jun-Ichi |
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Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia.
PloS one 2012 7 (2): e30819. Wong Michelle, Öhrmalm Lars, Broliden Kristina, Aust Carl, Hibberd Martin, Tolfvenstam Thom |
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[Study of irinotecan-induced toxicity and its correlation to UGT1A1 gene promoter polymorphisms].
Zhonghua fu chan ke za zhi 2011 Dec 46 (12): 888-91. Li Hu, Huang He, Liu Ji-ho |
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Impact of CYP3A5*3 and CYP2C8-HapC on paclitaxel/carboplatin-induced myelosuppression in patients with ovarian cancer.
Journal of pharmaceutical sciences 2011 Oct 100 (10): 4205-9. Gréen Henrik, Khan Muhammad Suleman, Jakobsen-Falk Ingrid, Åvall-Lundqvist Elisabeth, Peterson Cu |
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Autoimmune neutropenia in children: analysis of 116 cases.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2011 Aug 22 (5): 494-6. Audrain Marie, Martin Jérôme, Fromont Patricia, Prié Nolwen, Thomas Caroline, Muller Et Jean-Yv |
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Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients.
Clinical lung cancer 2011 Jul 12 (4): 224-30. Iranzo Vega, Sirera Rafael, Bremnes Roy M, Blasco Ana, Jantus-Lewintre Eloísa, Tarón Miquel, Berrocal Alfonso, Blasco Sara, Caballero Cristina, Del Pozo Nieves, Rosell Rafael, Camps Carl |
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Clinical implications of UGT1A1*28 genotype testing in colorectal cancer patients.
Cancer 2011 Jul 117 (14): 3156-62. Shulman Katerina, Cohen Ilana, Barnett-Griness Ofra, Kuten Abraham, Gruber Stephen B, Lejbkowicz Flavio, Rennert G |
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Mannose-binding lectin (MBL) as prognostic factor in paediatric oncology patients.
Clinical and experimental immunology 2011 Jul 165 (1): 51-9. Frakking F N J, Brouwer N, Dolman K M, van Woensel J B M, Caron H N, Kuijpers T W, van de Wetering M |
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