HuGE Literature Finder
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Records 1-50
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Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing.
Endocrine pathology 2018 Aug . Chang Ya-Sian, Chang Chun-Chi, Huang Hsi-Yuan, Lin Chien-Yu, Yeh Kun-Tu, Chang Jan-Gow |
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Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.
International journal of cancer 2018 Jul . Cheng Lei, Qiu Lixin, Zhang Ruoxin, Qian Danwen, Wang Mengyun, Sun Menghong, Zhu Xiaodong, Wang Yanong, Guo Weijian, Wei Qing |
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The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: A study of 142 cases.
Histopathology 2018 Jul . Urano Makoto, Hirai Hideaki, Tada Yuichiro, Kawakita Daisuke, Shimura Tomotaka, Tsukahara Kiyoaki, Kano Satoshi, Ozawa Hiroyuki, Okami Kenji, Sato Yuichiro, Fushimi Chihiro, Shimizu Akira, Takase Soichiro, Okada Takuro, Sato Hiroki, Imanishi Yorihisa, Otsuka Kuninori, Watanabe Yoshihiro, Sakai Akihiro, Ebisumoto Koji, Togashi Takafumi, Ueki Yushi, Ota Hisayuki, Sato Yukiko, Saigusa Natsuki, Nakaguro Masato, Hanazawa Toyoyuki, Nagao Toshita |
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LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.
Breast cancer research and treatment 2018 Jun . Van Swearingen Amanda E D, Siegel Marni B, Deal Allison M, Sambade Maria J, Hoyle Alan, Hayes D Neil, Jo Heejoon, Little Paul, Dees Elizabeth Claire, Muss Hyman, Jolly Trevor, Zagar Timothy M, Patel Nirali, Miller C Ryan, Parker Joel S, Smith J Keith, Fisher Julie, Shah Nikita, Nabell Lisle, Nanda Rita, Dillon Patrick, Abramson Vandana, Carey Lisa A, Anders Carey |
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Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.
Neoplasia (New York, N.Y.) 2018 May 20 (6): 574-593. Wang Xiaoxiao, Cao Xin, Sun Ruifang, Tang Charlene, Tzankov Alexandar, Zhang Jun, Manyam Ganiraju C, Xiao Min, Miao Yi, Jabbar Kausar, Tan Xiaohong, Pang Yuyang, Visco Carlo, Xie Yan, Dybkaer Karen, Chiu April, Orazi Attilio, Zu Youli, Bhagat Govind, Richards Kristy L, Hsi Eric D, Choi William W L, van Krieken J Han, Huh Jooryung, Ponzoni Maurilio, Ferreri Andrés J M, Møller Michael B, Parsons Ben M, Winter Jane N, Piris Miguel A, Li Shaoying, Miranda Roberto N, Medeiros L Jeffrey, Li Yong, Xu-Monette Zijun Y, Young Ken |
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Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.
Gene 2018 May . Ge Yuqiu, Liu Hanting, Qiu Xiaonan, Ma Gaoxiang, Wang Haixiao, Du Mulong, Wang Meilin, Zhao Qinghong, Tao Guoquan, Chu Haiyan, Zhang Zhengdo |
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PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer
Iranian biomedical journal 2018 Apr . Iranpour Mostafa, Nourian Mahyar, Saffari Sana, Samizadeh Esmaeil, Mirghafori Mahdieh, Iravani Shahrokh, Ghafouri-Fard Soud |
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Loss of PTEN in high grade advanced stage triple negative breast ductal cancers in African American women.
Pathology, research and practice 2018 Mar . Khan Farhan, Esnakula Ashwini, Ricks-Santi Luisel J, Zafar Rabia, Kanaan Yasmine, Naab Tamm |
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Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study.
British journal of cancer 2018 Mar . Lau David K, Tay Rebecca Y, Yeung Yvonne H, Chionh Fiona, Mooi Jennifer, Murone Carmel, Skrinos Effie, Price Timothy J, Mariadason John M, Tebbutt Niall |
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Analysis of 10 Adrenocortical Carcinoma Patients in the Cohort of the Precision Medicine Platform MONDTI.
Oncology 2018 Feb . Kieler Markus, Müllauer Leonhard, Koperek Oskar, Bianconi Daniela, Unseld Matthias, Raderer Markus, Prager Gerald |
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Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival.
European journal of cancer (Oxford, England : 1990) 2018 Jan 91 47-55. Dubot C, Bernard V, Sablin M P, Vacher S, Chemlali W, Schnitzler A, Pierron G, Ait Rais K, Bessoltane N, Jeannot E, Klijanienko J, Mariani O, Jouffroy T, Calugaru V, Hoffmann C, Lesnik M, Badois N, Berger F, Le Tourneau C, Kamal M, Bieche |
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Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.
European journal of cancer (Oxford, England : 1990) 2018 03 92 1-10. Verlingue Loic, Hollebecque Antoine, Lacroix Ludovic, Postel-Vinay Sophie, Varga Andrea, El Dakdouki Yolla, Baldini Capucine, Balheda Rastilav, Gazzah Anas, Michot Jean-Marie, Marabelle Aurélien, Mir Olivier, Arnedos Monica, Rouleau Etienne, Solary Eric, De Baere Thierry, Angevin Eric, Armand Jean-Pierre, Michiels Stefan, André Fabrice, Deutsch Eric, Scoazec Jean-Yves, Soria Jean-Charles, Massard Christop |
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Analysis of TSC1 mutation spectrum in mucosal melanoma.
Journal of cancer research and clinical oncology 2017 Nov . Ma Meng, Dai Jie, Xu Tianxiao, Yu Sifan, Yu Huan, Tang Huan, Yan Junya, Wu Xiaowen, Yu Jiayi, Chi Zhihong, Si Lu, Cui Chuanliang, Sheng Xinan, Kong Yan, Guo J |
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Molecular Landscape of Non-Muscle Invasive Bladder Cancer.
Cancer cell 2017 Nov 32 (5): 550-551. Meeks Joshua J, Lerner Seth |
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Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.
European urology 2016 Oct . Hsieh James J, Chen David, Wang Patricia I, Marker Mahtab, Redzematovic Almedina, Chen Ying-Bei, Selcuklu S Duygu, Weinhold Nils, Bouvier Nancy, Huberman Kety H, Bhanot Umesh, Chevinsky Michael S, Patel Parul, Pinciroli Patrizia, Won Helen H, You Daoqi, Viale Agnes, Lee William, Hakimi A Ari, Berger Michael F, Socci Nicholas D, Cheng Emily H, Knox Jennifer, Voss Martin H, Voi Maurizio, Motzer Robert |
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Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.
Nature communications 2016 Oct 7 13131. Chen Ying-Bei, Xu Jianing, Skanderup Anders Jacobsen, Dong Yiyu, Brannon A Rose, Wang Lu, Won Helen H, Wang Patricia I, Nanjangud Gouri J, Jungbluth Achim A, Li Wei, Ojeda Virginia, Hakimi A Ari, Voss Martin H, Schultz Nikolaus, Motzer Robert J, Russo Paul, Cheng Emily H, Giancotti Filippo G, Lee William, Berger Michael F, Tickoo Satish K, Reuter Victor E, Hsieh James |
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Comprehensive mutation profiling of mucinous gastric carcinoma.
The Journal of pathology 2016 Jun . Rokutan Hirofumi, Hosoda Fumie, Hama Natsuko, Nakamura Hiromi, Totoki Yasushi, Furukawa Eisaku, Arakawa Erika, Ohashi Shoko, Urushidate Tomoko, Satoh Hironori, Shimizu Hiroko, Igarashi Keiko, Yachida Shinichi, Katai Hitoshi, Taniguchi Hirokazu, Fukayama Masashi, Shibata Tatsuhi |
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Effects of the multikinase inhibitors Sorafenib and Regorafenib in PTEN deficient neoplasias.
European journal of cancer (Oxford, England : 1990) 2016 Jun 63 74-87. Mirantes Cristina, Dosil Maria Alba, Eritja Núria, Felip Isidre, Gatius Sònia, Santacana Maria, Matias-Guiu Xavier, Dolcet Xavi |
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A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma.
Clinical colorectal cancer 2016 Mar . Bowles Daniel W, Kochenderfer Mark, Cohn Allen, Sideris Lucas, Nguyen Nghia, Cline-Burkhardt Vivian, Schnadig Ian, Choi Minsig, Nabell Lisle, Chaudhry Arvind, Ruxer Robert, Ucar Antonio, Hausman Diana, Walker Luke, Spira Alexander, Jimeno Anton |
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Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic Renal Cell Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb . Kwiatkowski David J, Choueiri Toni K, Fay Andre P, Rini Brian I, Thorner Aaron R, De Velasco Guillermo, Tyburczy Magdalena, Hamieh Lana, Albiges Laurence, Agarwal Neeraj, Ho Thai H, Song Jiaxi, Pignon Jean-Christophe, Barrios Pablo M, Michaelson M Dror, Van Allen Eliezer M, Krajewski Katherine M, Porta Camillo, Pal Sumanta Kumar, Bellmunt Joaquim, McDermott David F, Heng Daniel Y C, Gray Kathryn P, Signoretti Sabi |
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Pulmonary Neoplasms in Patients with Birt-Hogg-Dubé Syndrome: Histopathological Features and Genetic and Somatic Events.
PloS one 2016 11 (3): e0151476. Furuya Mitsuko, Tanaka Reiko, Okudela Koji, Nakamura Satoko, Yoshioka Hiromu, Tsuzuki Toyonori, Shibuya Ryo, Yatera Kazuhiro, Shirasaki Hiroki, Sudo Yoshiko, Kimura Naoko, Yamada Kazuaki, Uematsu Shugo, Kunimura Toshiaki, Kato Ikuma, Nakatani Yuk |
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Genetic alterations in endometrial cancer by targeted next-generation sequencing.
Experimental and molecular pathology 2015 Nov . Chang Ya-Sian, Huang Hsien-Da, Yeh Kun-Tu, Chang Jan-Gow |
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The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study.
The Journal of pathology 2015 May . Guerini-Rocco Elena, Hodi Zsolt, Piscuoglio Salvatore, Ng Charlotte Ky, Rakha Emad A, Schultheis Anne M, Marchiò Caterina, da Cruz Paula Arnaud, De Filippo Maria R, Martelotto Luciano G, De Mattos-Arruda Leticia, Edelweiss Marcia, Jungbluth Achim A, Fusco Nicola, Norton Larry, Weigelt Britta, Ellis Ian O, Reis-Filho Jorge |
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Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
PloS one 2015 10 (8): e0136447. Piao Ying, Li Ying, Xu Qian, Liu Jing-Wei, Xing Cheng-Zhong, Xie Xiao-Dong, Yuan Yu |
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Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome.
International journal of cancer. Journal international du cancer 2014 Sep 135 (6): 1330-42. Arai Eri, Sakamoto Hiromi, Ichikawa Hitoshi, Totsuka Hirohiko, Chiku Suenori, Gotoh Masahiro, Mori Taisuke, Nakatani Tamao, Ohnami Sumiko, Nakagawa Tohru, Fujimoto Hiroyuki, Wang Linghua, Aburatani Hiroyuki, Yoshida Teruhiko, Kanai Y |
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A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Journal of cancer research and clinical oncology 2014 Aug 140 (8): 1399-411. Wang Xiaoting, Lin Youdong, Lan Fenghua, Yu Yinghao, Ouyang Xuenong, Wang Xuzhou, Huang Qiaojia, Wang Lie, Tan Jianming, Zheng Fe |
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Association of mTOR polymorphisms with cancer risk and clinical outcomes: a meta-analysis.
PloS one 2014 9 (5): e97085. Shao Jianbo, Li Ying, Zhao Peiwei, Yue Xin, Jiang Jun, Liang Xiaohui, He Xueli |
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Associations between single-nucleotide polymorphisms in the PI3K-PTEN-AKT-mTOR pathway and increased risk of brain metastasis in patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Nov 19 (22): 6252-60. Li Qianxia, Yang Ju, Yu Qianqian, Wu Huanlei, Liu Bo, Xiong Huihua, Hu Guangyuan, Zhao Jing, Yuan Xianglin, Liao Zhongxi |
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Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.
Molecular carcinogenesis 2013 Nov 52 Suppl 1 E70-9. He Jing, Wang Meng-Yun, Qiu Li-Xin, Zhu Mei-Ling, Shi Ting-Yan, Zhou Xiao-Yan, Sun Meng-Hong, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Li Jin, Yu Hong-Ping, Wei Qing- |
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Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 Jun 8 (6): 788-95. Zhu Mei-Ling, Yu Hongping, Shi Ting-Yan, He Jing, Wang Meng-Yun, Li Qiao-Xin, Sun Meng-Hong, Jin Li, Yang Ya-Jun, Wang Jiu-Cun, Xiang Jia-Qing, Wei Qing- |
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A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.
PloS one 2013 8 (3): e60080. Xu Ming, Tao Guoquan, Kang Meiyun, Gao Yan, Zhu Haixia, Gong Weida, Wang Meilin, Wu Dongmei, Zhang Zhengdong, Zhao Qingho |
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Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population.
PloS one 2013 8 (8): e71968. Li Qiaoxin, Gu Chengyuan, Zhu Yao, Wang Mengyun, Yang Yajun, Wang Jiucun, Jin Li, Zhu Mei-Ling, Shi Ting-Yan, He Jing, Zhou Xiaoyan, Ye Ding-wei, Wei Qing |
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A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk.
PloS one 2012 7 (11): 11. Cao Q, Ju X, Li P, Meng X, Shao P, Cai H, Wang M, Zhang Z, Qin C, Yin C |
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Association of genetic variations in mTOR with risk of childhood acute lymphoblastic leukemia in a Chinese population.
Leukemia & lymphoma 2012 May 53 (5): 947-51. Huang Lizhen, Huang Jie, Wu Peng, Li Qian, Rong Liucheng, Xue Yao, Lu Qin, Li Jie, Tong Na, Wang Meilin, Zhang Zhengdong, Fang Yongj |
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Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.
Journal of cancer research and clinical oncology 2012 Mar 138 (3): 377-85. Wang Li-E, Ma Hongxia, Hale Katherine S, Yin Ming, Meyer Larissa A, Liu Hongliang, Li Jie, Lu Karen H, Hennessy Bryan T, Li Xuesong, Spitz Margaret R, Wei Qingyi, Mills Gordon |
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[Association of genetic polymorphisms of key molecules in JAK/STAT signaling pathway with susceptibility of hepatocellular carcinoma].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2012 Feb 33 (2): 215-9. Xie Jia-xin, Yin Jian-hua, Zhang Qi, Pu Rui, Zhang Yu-wei, Lu Wen-ying, Cao Guang-w |
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Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.
PloS one 2012 7 (7): e40817. Chen Jiawei, Shao Pengfei, Cao Qiang, Li Pu, Li Jie, Cai Hongzhou, Zhu Jian, Wang Meilin, Zhang Zhengdong, Qin Chao, Yin Changj |
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Novel somatic mutations to PI3K pathway genes in metastatic melanoma.
PloS one 2012 7 (8): e43369. Shull Austin Y, Latham-Schwark Alicia, Ramasamy Poornema, Leskoske Kristin, Oroian Dora, Birtwistle Marc R, Buckhaults Phillip |
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Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Nutrition and cancer 2011 Nov 63 (8): 1226-34. Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Caan Bette J, Potter John D, Wolff Roger |
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Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.
Carcinogenesis 2011 Apr 32 (4): 502-6. Wu I-Chen, Zhao Yang, Zhai Rihong, Liu Chen-yu, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Su Li, Heist Rebecca S, Kulke Matthew H, Liu Geoffrey, Christiani David |
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Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 628. Lee S J, Kim J G, Chae Y S, Kang B W, Jeon S W, Park J S, Park J Y, Choi G S, Lee Y |
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Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Haematologica 2011 Feb 96 (2): 323-7. Casabonne Delphine, Reina Oscar, Benavente Yolanda, Becker Nikolaus, Maynadié Marc, Foretová Lenka, Cocco Pierluigi, González-Neira Anna, Nieters Alexandra, Boffetta Paolo, Middeldorp Jaap M, de Sanjose Silv |
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Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
Mutation research 2011 Jan 706 (1-2): 13-20. Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Wolff Roger |
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PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.
Lung cancer (Amsterdam, Netherlands) 2011 Jan 71 (1): 82-8. Pu Xia, Hildebrandt Michelle A T, Lu Charles, Lin Jie, Stewart David J, Ye Yuanqing, Gu Jian, Spitz Margaret R, Wu Xife |
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Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
PloS one 2011 6 (2): e16914. Campa Daniele, Hüsing Anika, Stein Angelika, Dostal Lucie, Boeing Heiner, Pischon Tobias, Tjønneland Anne, Roswall Nina, Overvad Kim, Østergaard Jane Nautrup, Rodríguez Laudina, Sala Núria, Sánchez Maria-José, Larrañaga Nerea, Huerta José María, Barricarte Aurelio, Khaw Kay-Tee, Wareham Nicholas, Travis Ruth C, Allen Naomi E, Lagiou Pagona, Trichopoulou Antonia, Trichopoulos Dimitrios, Palli Domenico, Sieri Sabina, Tumino Rosario, Sacerdote Carlotta, van Kranen Henk, Bueno-de-Mesquita H Bas, Hallmans Göran, Johansson Mattias, Romieu Isabelle, Jenab Mazda, Cox David G, Siddiq Afshan, Riboli Elio, Canzian Federico, Kaaks Rudo |
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Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Carcinogenesis 2010 Sep 31 (9): 1604-11. Slattery Martha L, Herrick Jennifer S, Lundgreen Abbie, Fitzpatrick Francis A, Curtin Karen, Wolff Roger |
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A Large-scale genetic association study of esophageal adenocarcinoma risk.
Carcinogenesis 2010 Jul 31 (7): 1259-63. Liu Chen-Yu, Wu Michael C, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Zhai Rihong, Wang Zhaoxi, Su Li, Heist Rebecca S, Kulke Matthew H, Lin Xihong, Liu Geoffrey, Christiani David |
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Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Oncology 2010 79 (3-4): 278-82. Kim Jong Gwang, Chae Yee Soo, Sohn Sang Kyun, Kang Byung Woog, Moon Joon Ho, Lee Soo Jung, Jeon Seong Woo, Park Jun Seok, Park Jin Young, Choi Gyu Se |
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Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Feb 27 (6): 857-71. Hildebrandt Michelle A T, Yang Hushan, Hung Mien-Chie, Izzo Julie G, Huang Maosheng, Lin Jie, Ajani Jaffer A, Wu Xife |
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Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men.
Dementia and geriatric cognitive disorders 2009 27 (1): 59-68. Giedraitis Vilmantas, Kilander Lena, Degerman-Gunnarsson Malin, Sundelöf Johan, Axelsson Tomas, Syvänen Ann-Christine, Lannfelt Lars, Glaser An |
- Page last reviewed:Mar 1, 2018
- Page last updated:Jul 18, 2019
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