HuGE Literature Finder
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Records 1-79
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Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.
British journal of cancer 2018 Sep 119 (6): 707-712. Bellmunt Joaquim, Lalani Aly-Khan A, Jacobus Sussana, Wankowicz Stephanie A, Polacek Laura, Takeda David Y, Harshman Lauren C, Wagle Nikhil, Moreno Irene, Lundgren Kevin, Bossé Dominick, Van Allen Eliezer M, Choueiri Toni K, Rosenberg Jonathan |
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Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing.
Endocrine pathology 2018 Aug . Chang Ya-Sian, Chang Chun-Chi, Huang Hsi-Yuan, Lin Chien-Yu, Yeh Kun-Tu, Chang Jan-Gow |
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Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.
International journal of cancer 2018 Jul . Cheng Lei, Qiu Lixin, Zhang Ruoxin, Qian Danwen, Wang Mengyun, Sun Menghong, Zhu Xiaodong, Wang Yanong, Guo Weijian, Wei Qing |
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Targeted Next-Generation Sequencing in Men with Metastatic Prostate Cancer: a Pilot Study.
Targeted oncology 2018 Jul . Barata Pedro C, Mendiratta Prateek, Heald Brandie, Klek Stefan, Grivas Petros, Sohal Davendra P S, Garcia Jorge |
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The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: A study of 142 cases.
Histopathology 2018 Jul . Urano Makoto, Hirai Hideaki, Tada Yuichiro, Kawakita Daisuke, Shimura Tomotaka, Tsukahara Kiyoaki, Kano Satoshi, Ozawa Hiroyuki, Okami Kenji, Sato Yuichiro, Fushimi Chihiro, Shimizu Akira, Takase Soichiro, Okada Takuro, Sato Hiroki, Imanishi Yorihisa, Otsuka Kuninori, Watanabe Yoshihiro, Sakai Akihiro, Ebisumoto Koji, Togashi Takafumi, Ueki Yushi, Ota Hisayuki, Sato Yukiko, Saigusa Natsuki, Nakaguro Masato, Hanazawa Toyoyuki, Nagao Toshita |
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Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance.
Lung cancer (Amsterdam, Netherlands) 2018 Jun 120 113-121. Du Meijun, Thompson Jonathan, Fisher Hannah, Zhang Peng, Huang Chiang-Ching, Wang Lia |
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LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.
Breast cancer research and treatment 2018 Jun . Van Swearingen Amanda E D, Siegel Marni B, Deal Allison M, Sambade Maria J, Hoyle Alan, Hayes D Neil, Jo Heejoon, Little Paul, Dees Elizabeth Claire, Muss Hyman, Jolly Trevor, Zagar Timothy M, Patel Nirali, Miller C Ryan, Parker Joel S, Smith J Keith, Fisher Julie, Shah Nikita, Nabell Lisle, Nanda Rita, Dillon Patrick, Abramson Vandana, Carey Lisa A, Anders Carey |
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Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.
Neoplasia (New York, N.Y.) 2018 May 20 (6): 574-593. Wang Xiaoxiao, Cao Xin, Sun Ruifang, Tang Charlene, Tzankov Alexandar, Zhang Jun, Manyam Ganiraju C, Xiao Min, Miao Yi, Jabbar Kausar, Tan Xiaohong, Pang Yuyang, Visco Carlo, Xie Yan, Dybkaer Karen, Chiu April, Orazi Attilio, Zu Youli, Bhagat Govind, Richards Kristy L, Hsi Eric D, Choi William W L, van Krieken J Han, Huh Jooryung, Ponzoni Maurilio, Ferreri Andrés J M, Møller Michael B, Parsons Ben M, Winter Jane N, Piris Miguel A, Li Shaoying, Miranda Roberto N, Medeiros L Jeffrey, Li Yong, Xu-Monette Zijun Y, Young Ken |
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Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.
Gene 2018 May . Ge Yuqiu, Liu Hanting, Qiu Xiaonan, Ma Gaoxiang, Wang Haixiao, Du Mulong, Wang Meilin, Zhao Qinghong, Tao Guoquan, Chu Haiyan, Zhang Zhengdo |
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PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer
Iranian biomedical journal 2018 Apr . Iranpour Mostafa, Nourian Mahyar, Saffari Sana, Samizadeh Esmaeil, Mirghafori Mahdieh, Iravani Shahrokh, Ghafouri-Fard Soud |
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Loss of PTEN in high grade advanced stage triple negative breast ductal cancers in African American women.
Pathology, research and practice 2018 Mar . Khan Farhan, Esnakula Ashwini, Ricks-Santi Luisel J, Zafar Rabia, Kanaan Yasmine, Naab Tamm |
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Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study.
British journal of cancer 2018 Mar . Lau David K, Tay Rebecca Y, Yeung Yvonne H, Chionh Fiona, Mooi Jennifer, Murone Carmel, Skrinos Effie, Price Timothy J, Mariadason John M, Tebbutt Niall |
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Analysis of 10 Adrenocortical Carcinoma Patients in the Cohort of the Precision Medicine Platform MONDTI.
Oncology 2018 Feb . Kieler Markus, Müllauer Leonhard, Koperek Oskar, Bianconi Daniela, Unseld Matthias, Raderer Markus, Prager Gerald |
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Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival.
European journal of cancer (Oxford, England : 1990) 2018 Jan 91 47-55. Dubot C, Bernard V, Sablin M P, Vacher S, Chemlali W, Schnitzler A, Pierron G, Ait Rais K, Bessoltane N, Jeannot E, Klijanienko J, Mariani O, Jouffroy T, Calugaru V, Hoffmann C, Lesnik M, Badois N, Berger F, Le Tourneau C, Kamal M, Bieche |
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Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Cancer 2018 Jan . Ross Jeffrey S, Fakih Marwan, Ali Siraj M, Elvin Julia A, Schrock Alexa B, Suh James, Vergilio Jo-Anne, Ramkissoon Shakti, Severson Eric, Daniel Sugganth, Fabrizio David, Frampton Garrett, Sun James, Miller Vincent A, Stephens Philip J, Gay Laurie |
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Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.
European journal of cancer (Oxford, England : 1990) 2018 03 92 1-10. Verlingue Loic, Hollebecque Antoine, Lacroix Ludovic, Postel-Vinay Sophie, Varga Andrea, El Dakdouki Yolla, Baldini Capucine, Balheda Rastilav, Gazzah Anas, Michot Jean-Marie, Marabelle Aurélien, Mir Olivier, Arnedos Monica, Rouleau Etienne, Solary Eric, De Baere Thierry, Angevin Eric, Armand Jean-Pierre, Michiels Stefan, André Fabrice, Deutsch Eric, Scoazec Jean-Yves, Soria Jean-Charles, Massard Christop |
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Associations of genetic polymorphisms in pTEN/AKT/mTOR signaling pathway genes with cancer risk: A meta-analysis in Asian population.
Scientific reports 2017 Dec 7 (1): 17844. Zhang Zhen, Chen Qiuchen, Zhang Jing, Wang Yilin, Hu Xiaoyun, Yin Sainan, He Miao, Guan Shu, Qin Wenyan, Xiao Qinghuan, Zhao Haishan, Yao Weifan, Wu Huizhe, Wei Minj |
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Analysis of TSC1 mutation spectrum in mucosal melanoma.
Journal of cancer research and clinical oncology 2017 Nov . Ma Meng, Dai Jie, Xu Tianxiao, Yu Sifan, Yu Huan, Tang Huan, Yan Junya, Wu Xiaowen, Yu Jiayi, Chi Zhihong, Si Lu, Cui Chuanliang, Sheng Xinan, Kong Yan, Guo J |
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Molecular Landscape of Non-Muscle Invasive Bladder Cancer.
Cancer cell 2017 Nov 32 (5): 550-551. Meeks Joshua J, Lerner Seth |
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Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer.
Cancer chemotherapy and pharmacology 2017 Jul . Mbatchi Litaty C, Gassiot Matthieu, Pourquier Philippe, Goberna Alejando, Mahammedi Hakim, Mourey Loic, Joly Florence, Lumbroso Serge, Evrard Alexandre, Houede Nadi |
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Association of breast cancer risk and the mTOR pathway in women of African ancestry in "The Root" Consortium.
Carcinogenesis 2017 Jun . Wang Shengfeng, Huo Dezheng, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Nathanson Katherine L, Nemesure Barbara, Ambs Stefan, Olopade Olufunmilayo I, Zheng Yongl |
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Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
British journal of cancer 2017 Jun 117 (1): 136-143. Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaet |
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Identification of novel mutations in endometrial cancer patients by whole-exome sequencing.
International journal of oncology 2017 Mar . Chang Ya-Sian, Huang Hsien-Da, Yeh Kun-Tu, Chang Jan-Gow |
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Copy number variations of E2F1: a new genetic risk factor for testicular cancer.
Endocrine-related cancer 2017 Jan . Rocca Maria Santa, Di Nisio Andrea, Marchiori Arianna, Ghezzi Marco, Opocher Giuseppe, Foresta Carlo, Ferlin Alber |
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A phase II study of temsirolimus added to low-dose weekly carboplatin and paclitaxel for patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).
Annals of oncology : official journal of the European Society for Medical Oncology 2017 10 28 (10): 2533-2538. Dunn L A, Fury M G, Xiao H, Baxi S S, Sherman E J, Korte S, Pfister C, Haque S, Katabi N, Ho A L, Pfister D |
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MicroRNA-Related Polymorphisms in PI3K/Akt/mTOR Pathway Genes Are Predictive of Limited-Disease Small Cell Lung Cancer Treatment Outcomes.
BioMed research international 2017 2017 6501385. Jiang Wei, Zhang Wenjue, Wu Lihong, Liu Lipin, Men Yu, Wang Jingbo, Liang Jun, Hui Zhouguang, Zhou Zongmei, Bi Nan, Wang Luh |
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Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer.
PloS one 2017 12 (7): e0180192. Pascual Tomas, Apellániz-Ruiz María, Pernaut Cristina, Cueto-Felgueroso Cecilia, Villalba Pablo, Álvarez Carlos, Manso Luis, Inglada-Pérez Lucia, Robledo Mercedes, Rodríguez-Antona Cristina, Ciruelos E |
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Everolimus in patients with advanced follicular-derived thyroid cancer; results of a phase II clinical trial.
The Journal of clinical endocrinology and metabolism 2016 Nov jc20162525. Schneider T C, de Wit D, Links T P, van Erp N P, van der Hoeven J J M, Gelderblom H, Roozen C F M, Bos M, Corver W E, van Wezel T, Smit J W A, Morreau H, Guchelaar H J, Kapiteijn |
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Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy.
Scientific reports 2016 Nov 6 37576. Guo Qiaojuan, Lu Tianzhu, Chen Yan, Su Ying, Zheng Yuhong, Chen Zeng, Chen Chao, Lin Shaojun, Pan Jianji, Yuan Xiangl |
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Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.
European urology 2016 Oct . Hsieh James J, Chen David, Wang Patricia I, Marker Mahtab, Redzematovic Almedina, Chen Ying-Bei, Selcuklu S Duygu, Weinhold Nils, Bouvier Nancy, Huberman Kety H, Bhanot Umesh, Chevinsky Michael S, Patel Parul, Pinciroli Patrizia, Won Helen H, You Daoqi, Viale Agnes, Lee William, Hakimi A Ari, Berger Michael F, Socci Nicholas D, Cheng Emily H, Knox Jennifer, Voss Martin H, Voi Maurizio, Motzer Robert |
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Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.
Nature communications 2016 Oct 7 13131. Chen Ying-Bei, Xu Jianing, Skanderup Anders Jacobsen, Dong Yiyu, Brannon A Rose, Wang Lu, Won Helen H, Wang Patricia I, Nanjangud Gouri J, Jungbluth Achim A, Li Wei, Ojeda Virginia, Hakimi A Ari, Voss Martin H, Schultz Nikolaus, Motzer Robert J, Russo Paul, Cheng Emily H, Giancotti Filippo G, Lee William, Berger Michael F, Tickoo Satish K, Reuter Victor E, Hsieh James |
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Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach.
Oncotarget 2016 Oct . Fiorentino Michelangelo, Gruppioni Elisa, Massari Francesco, Giunchi Francesca, Altimari Annalisa, Ciccarese Chiara, Bimbatti Davide, Scarpa Aldo, Iacovelli Roberto, Porta Camillo, Virinder Sarhadi, Tortora Giampaolo, Artibani Walter, Schiavina Riccardo, Ardizzoni Andrea, Brunelli Matteo, Knuutila Sakari, Martignoni Gui |
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Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population.
Oncotarget 2016 Sep 7 (36): 58174-58180. Zhao Yang, Diao Yan, Wang XiJing, Lin Shuai, Wang Meng, Kang HuaFeng, Yang PengTao, Dai Cong, Liu XingHan, Liu Kang, Li ShanLi, Zhu YuYao, Dai ZhiJ |
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Genomic profiling of large-cell neuroendocrine carcinoma of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Aug . Miyoshi Tomohiro, Umemura Shigeki, Matsumura Yuki, Mimaki Sachiyo, Tada Satoshi, Ishii Genichiro, Udagawa Hibiki, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Ohmatsu Hironobu, Aokage Keiju, Hishida Tomoyuki, Yoshida Junji, Nagai Kanji, Goto Koichi, Tsuboi Masahiro, Tsuchihara Katsu |
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Targeted Exome Sequencing of the Cancer Genome in Patients with Very High-risk Bladder Cancer.
European urology 2016 Aug . Longo Thomas, McGinley Kathleen F, Freedman Jennifer A, Etienne Wiguins, Wu Yuan, Sibley Alexander, Owzar Kouros, Gresham Jeremy, Moy Christopher, Szabo Stephen, Greshock Joel, Zhou Hui, Bai Yuchen, Inman Brant |
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Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis.
Oncotarget 2016 Jul . Zining Jin, Lu Xu, Caiyun He, Yuan Yu |
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Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer.
Oncotarget 2016 Jul . Wei Runmin, De Vivo Immaculata, Huang Sijia, Zhu Xun, Risch Harvey, Moore Jason H, Yu Herbert, Garmire Lana |
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Comprehensive mutation profiling of mucinous gastric carcinoma.
The Journal of pathology 2016 Jun . Rokutan Hirofumi, Hosoda Fumie, Hama Natsuko, Nakamura Hiromi, Totoki Yasushi, Furukawa Eisaku, Arakawa Erika, Ohashi Shoko, Urushidate Tomoko, Satoh Hironori, Shimizu Hiroko, Igarashi Keiko, Yachida Shinichi, Katai Hitoshi, Taniguchi Hirokazu, Fukayama Masashi, Shibata Tatsuhi |
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Effects of the multikinase inhibitors Sorafenib and Regorafenib in PTEN deficient neoplasias.
European journal of cancer (Oxford, England : 1990) 2016 Jun 63 74-87. Mirantes Cristina, Dosil Maria Alba, Eritja Núria, Felip Isidre, Gatius Sònia, Santacana Maria, Matias-Guiu Xavier, Dolcet Xavi |
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Molecular Profiling of Clear Cell Ovarian Cancers: Identifying Potential Treatment Targets for Clinical Trials.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2016 May 26 (4): 648-54. Friedlander Michael L, Russell Kenneth, Millis Sherri, Gatalica Zoran, Bender Ryan, Voss Andre |
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Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection.
British journal of cancer 2016 May . Cacheux Wulfran, Rouleau Etienne, Briaux Adrien, Tsantoulis Petros, Mariani Pascale, Richard-Molard Marion, Buecher Bruno, Dangles-Marie Virginie, Richon Sophie, Lazartigues Julien, Jeannot Emmanuelle, Farkhondeh Fereshteh, Sastre-Garau Xavier, de La Rochefordière Anne, Labib Alain, Falcou Marie-Christine, Stevens Denise, Roth Arnaud, Roman-Roman Sergio, Mitry Emmanuel, Bièche Ivan, Lièvre Astr |
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Study of single nucleotide polymorphisms of FBW7 and its substrate genes revealed a predictive factor for paclitaxel plus cisplatin chemotherapy in Chinese patients with advanced esophageal squamous cell carcinoma.
Oncotarget 2016 May . Liu Ying, Xu Shu Ning, Chen Yong Shun, Wu Xiao Yuan, Qiao Lei, Li Ke, Yuan Lo |
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Targeted sequencing identifies genetic alterations that confer Primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium).
Oncotarget 2016 Apr . Lim Sun Min, Kim Hye Ryun, Cho Eun Kyung, Min Young Joo, Ahn Jin Seok, Ahn Myung-Ju, Park Keunchil, Cho Byoung Chul, Lee Ji-Hyun, Jeong Hye Cheol, Kim Eun Kyung, Kim Joo-Ha |
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A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma.
Clinical colorectal cancer 2016 Mar . Bowles Daniel W, Kochenderfer Mark, Cohn Allen, Sideris Lucas, Nguyen Nghia, Cline-Burkhardt Vivian, Schnadig Ian, Choi Minsig, Nabell Lisle, Chaudhry Arvind, Ruxer Robert, Ucar Antonio, Hausman Diana, Walker Luke, Spira Alexander, Jimeno Anton |
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Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic Renal Cell Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb . Kwiatkowski David J, Choueiri Toni K, Fay Andre P, Rini Brian I, Thorner Aaron R, De Velasco Guillermo, Tyburczy Magdalena, Hamieh Lana, Albiges Laurence, Agarwal Neeraj, Ho Thai H, Song Jiaxi, Pignon Jean-Christophe, Barrios Pablo M, Michaelson M Dror, Van Allen Eliezer M, Krajewski Katherine M, Porta Camillo, Pal Sumanta Kumar, Bellmunt Joaquim, McDermott David F, Heng Daniel Y C, Gray Kathryn P, Signoretti Sabi |
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Prognostic and Therapeutic Markers in Chordomas: A Study of 287 Tumors.
Journal of neuropathology and experimental neurology 2016 Feb 75 (2): 111-20. Tauziéde-Espariat Arnault, Bresson Damien, Polivka Marc, Bouazza Schahrazed, Labrousse François, Aronica Eleonora, Pretet Jean-Luc, Projetti Fabrice, Herman Philippe, Salle Henri, Monnien Franck, Valmary-Degano Séverine, Laquerrière Annie, Pocard Marc, Chaigneau Loïc, Isambert Nicolas, Aubriot-Lorton Marie-Hélène, Feuvret Loïc, George Bernard, Froelich Sébastien, Adle-Biassette Ho |
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Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women.
Cancer causes & control : CCC 2016 08 27 (8): 965-76. Cheng Ting-Yuan David, Shankar Jyoti, Zirpoli Gary, Roberts Michelle R, Hong Chi-Chen, Bandera Elisa V, Ambrosone Christine B, Yao So |
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Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome.
Scientific reports 2016 6 21252. Lakiotaki Eleftheria, Levidou Georgia, Angelopoulou Maria K, Adamopoulos Christos, Pangalis Gerassimos, Rassidakis George, Vassilakopoulos Theodoros, Gainaru Gabriella, Flevari Pagona, Sachanas Sotirios, Saetta Angelica A, Sepsa Athanasia, Moschogiannis Maria, Kalpadakis Christina, Tsesmetzis Nikolaos, Milionis Vassilios, Chatziandreou Ilenia, Thymara Irene, Panayiotidis Panayiotis, Dimopoulou Maria, Plata Eleni, Konstantopoulos Konstantinos, Patsouris Efstratios, Piperi Christina, Korkolopoulou Penelo |
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Pulmonary Neoplasms in Patients with Birt-Hogg-Dubé Syndrome: Histopathological Features and Genetic and Somatic Events.
PloS one 2016 11 (3): e0151476. Furuya Mitsuko, Tanaka Reiko, Okudela Koji, Nakamura Satoko, Yoshioka Hiromu, Tsuzuki Toyonori, Shibuya Ryo, Yatera Kazuhiro, Shirasaki Hiroki, Sudo Yoshiko, Kimura Naoko, Yamada Kazuaki, Uematsu Shugo, Kunimura Toshiaki, Kato Ikuma, Nakatani Yuk |
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Genetic alterations in endometrial cancer by targeted next-generation sequencing.
Experimental and molecular pathology 2015 Nov . Chang Ya-Sian, Huang Hsien-Da, Yeh Kun-Tu, Chang Jan-Gow |
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The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study.
The Journal of pathology 2015 May . Guerini-Rocco Elena, Hodi Zsolt, Piscuoglio Salvatore, Ng Charlotte Ky, Rakha Emad A, Schultheis Anne M, Marchiò Caterina, da Cruz Paula Arnaud, De Filippo Maria R, Martelotto Luciano G, De Mattos-Arruda Leticia, Edelweiss Marcia, Jungbluth Achim A, Fusco Nicola, Norton Larry, Weigelt Britta, Ellis Ian O, Reis-Filho Jorge |
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Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
PloS one 2015 10 (8): e0136447. Piao Ying, Li Ying, Xu Qian, Liu Jing-Wei, Xing Cheng-Zhong, Xie Xiao-Dong, Yuan Yu |
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Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome.
International journal of cancer. Journal international du cancer 2014 Sep 135 (6): 1330-42. Arai Eri, Sakamoto Hiromi, Ichikawa Hitoshi, Totsuka Hirohiko, Chiku Suenori, Gotoh Masahiro, Mori Taisuke, Nakatani Tamao, Ohnami Sumiko, Nakagawa Tohru, Fujimoto Hiroyuki, Wang Linghua, Aburatani Hiroyuki, Yoshida Teruhiko, Kanai Y |
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A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Journal of cancer research and clinical oncology 2014 Aug 140 (8): 1399-411. Wang Xiaoting, Lin Youdong, Lan Fenghua, Yu Yinghao, Ouyang Xuenong, Wang Xuzhou, Huang Qiaojia, Wang Lie, Tan Jianming, Zheng Fe |
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Association of mTOR polymorphisms with cancer risk and clinical outcomes: a meta-analysis.
PloS one 2014 9 (5): e97085. Shao Jianbo, Li Ying, Zhao Peiwei, Yue Xin, Jiang Jun, Liang Xiaohui, He Xueli |
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Associations between single-nucleotide polymorphisms in the PI3K-PTEN-AKT-mTOR pathway and increased risk of brain metastasis in patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Nov 19 (22): 6252-60. Li Qianxia, Yang Ju, Yu Qianqian, Wu Huanlei, Liu Bo, Xiong Huihua, Hu Guangyuan, Zhao Jing, Yuan Xianglin, Liao Zhongxi |
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Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.
Molecular carcinogenesis 2013 Nov 52 Suppl 1 E70-9. He Jing, Wang Meng-Yun, Qiu Li-Xin, Zhu Mei-Ling, Shi Ting-Yan, Zhou Xiao-Yan, Sun Meng-Hong, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Li Jin, Yu Hong-Ping, Wei Qing- |
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Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 Jun 8 (6): 788-95. Zhu Mei-Ling, Yu Hongping, Shi Ting-Yan, He Jing, Wang Meng-Yun, Li Qiao-Xin, Sun Meng-Hong, Jin Li, Yang Ya-Jun, Wang Jiu-Cun, Xiang Jia-Qing, Wei Qing- |
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A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.
PloS one 2013 8 (3): e60080. Xu Ming, Tao Guoquan, Kang Meiyun, Gao Yan, Zhu Haixia, Gong Weida, Wang Meilin, Wu Dongmei, Zhang Zhengdong, Zhao Qingho |
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Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population.
PloS one 2013 8 (8): e71968. Li Qiaoxin, Gu Chengyuan, Zhu Yao, Wang Mengyun, Yang Yajun, Wang Jiucun, Jin Li, Zhu Mei-Ling, Shi Ting-Yan, He Jing, Zhou Xiaoyan, Ye Ding-wei, Wei Qing |
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A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk.
PloS one 2012 7 (11): 11. Cao Q, Ju X, Li P, Meng X, Shao P, Cai H, Wang M, Zhang Z, Qin C, Yin C |
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Association of genetic variations in mTOR with risk of childhood acute lymphoblastic leukemia in a Chinese population.
Leukemia & lymphoma 2012 May 53 (5): 947-51. Huang Lizhen, Huang Jie, Wu Peng, Li Qian, Rong Liucheng, Xue Yao, Lu Qin, Li Jie, Tong Na, Wang Meilin, Zhang Zhengdong, Fang Yongj |
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Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.
Journal of cancer research and clinical oncology 2012 Mar 138 (3): 377-85. Wang Li-E, Ma Hongxia, Hale Katherine S, Yin Ming, Meyer Larissa A, Liu Hongliang, Li Jie, Lu Karen H, Hennessy Bryan T, Li Xuesong, Spitz Margaret R, Wei Qingyi, Mills Gordon |
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[Association of genetic polymorphisms of key molecules in JAK/STAT signaling pathway with susceptibility of hepatocellular carcinoma].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2012 Feb 33 (2): 215-9. Xie Jia-xin, Yin Jian-hua, Zhang Qi, Pu Rui, Zhang Yu-wei, Lu Wen-ying, Cao Guang-w |
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Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.
PloS one 2012 7 (7): e40817. Chen Jiawei, Shao Pengfei, Cao Qiang, Li Pu, Li Jie, Cai Hongzhou, Zhu Jian, Wang Meilin, Zhang Zhengdong, Qin Chao, Yin Changj |
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Novel somatic mutations to PI3K pathway genes in metastatic melanoma.
PloS one 2012 7 (8): e43369. Shull Austin Y, Latham-Schwark Alicia, Ramasamy Poornema, Leskoske Kristin, Oroian Dora, Birtwistle Marc R, Buckhaults Phillip |
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Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Nutrition and cancer 2011 Nov 63 (8): 1226-34. Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Caan Bette J, Potter John D, Wolff Roger |
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Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.
Carcinogenesis 2011 Apr 32 (4): 502-6. Wu I-Chen, Zhao Yang, Zhai Rihong, Liu Chen-yu, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Su Li, Heist Rebecca S, Kulke Matthew H, Liu Geoffrey, Christiani David |
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Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 628. Lee S J, Kim J G, Chae Y S, Kang B W, Jeon S W, Park J S, Park J Y, Choi G S, Lee Y |
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Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Haematologica 2011 Feb 96 (2): 323-7. Casabonne Delphine, Reina Oscar, Benavente Yolanda, Becker Nikolaus, Maynadié Marc, Foretová Lenka, Cocco Pierluigi, González-Neira Anna, Nieters Alexandra, Boffetta Paolo, Middeldorp Jaap M, de Sanjose Silv |
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Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
Mutation research 2011 Jan 706 (1-2): 13-20. Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Wolff Roger |
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PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.
Lung cancer (Amsterdam, Netherlands) 2011 Jan 71 (1): 82-8. Pu Xia, Hildebrandt Michelle A T, Lu Charles, Lin Jie, Stewart David J, Ye Yuanqing, Gu Jian, Spitz Margaret R, Wu Xife |
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Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
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Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Carcinogenesis 2010 Sep 31 (9): 1604-11. Slattery Martha L, Herrick Jennifer S, Lundgreen Abbie, Fitzpatrick Francis A, Curtin Karen, Wolff Roger |
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A Large-scale genetic association study of esophageal adenocarcinoma risk.
Carcinogenesis 2010 Jul 31 (7): 1259-63. Liu Chen-Yu, Wu Michael C, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Zhai Rihong, Wang Zhaoxi, Su Li, Heist Rebecca S, Kulke Matthew H, Lin Xihong, Liu Geoffrey, Christiani David |
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Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Oncology 2010 79 (3-4): 278-82. Kim Jong Gwang, Chae Yee Soo, Sohn Sang Kyun, Kang Byung Woog, Moon Joon Ho, Lee Soo Jung, Jeon Seong Woo, Park Jun Seok, Park Jin Young, Choi Gyu Se |
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Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Feb 27 (6): 857-71. Hildebrandt Michelle A T, Yang Hushan, Hung Mien-Chie, Izzo Julie G, Huang Maosheng, Lin Jie, Ajani Jaffer A, Wu Xife |
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Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men.
Dementia and geriatric cognitive disorders 2009 27 (1): 59-68. Giedraitis Vilmantas, Kilander Lena, Degerman-Gunnarsson Malin, Sundelöf Johan, Axelsson Tomas, Syvänen Ann-Christine, Lannfelt Lars, Glaser An |
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Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.
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