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| De Novo myelodysplastic syndromes in patients 20-50 years old are enriched for adverse risk features. Leukemia research 2022 Jun 117 106857. Epstein-Peterson Zachary D, Spitzer Barbara, Derkach Andriy, Arango Juan E, McCarter Joseph G W, Medina-Martínez Juan S, McGovern Erin, Farnoud Noushin Rahnamay, Levine Ross L, Tallman Martin |
| Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations. Annals of hematology 2022 Jan . Dutta Sayantanee, Moritz Jennifer, Pregartner Gudrun, Thallinger Gerhard G, Brandstätter Ilona, Lind Karin, Rezania Simin, Lyssy Freya, Reinisch Andreas, Zebisch Armin, Berghold Andrea, Wölfler Albert, Sill Hei |
| Decreased serum apolipoprotein A1 level predicts poor prognosis of patients with de novo myelodysplastic syndromes. BMC cancer 2022 Jan 22 (1): 127. Shi Cong, Gong Shengping, Wu An, Yang Shujun, Zou Duobing, Zhang Yi, Wu Ningning, Ma Chao, Shi Songqiu, Chen Ying, Wu Ying, Zheng Xiaojiao, Huang Zhenya, Ding Jianghua, Ouyang Guifang, Mu Qiti |
| TP53 mutation defines a unique subgroup within complex karyotype de novo and therapy-related MDS/AML. Blood advances 2022 Jan . Weinberg Olga K, Siddon Alexa J, Madanat Yazan, Gagan Jeffrey, Arber Daniel A, Dal Cin Paola, Narayanan Damodaran, Ouseph Madhu M, Kurzer Jason H, Hasserjian Robert |
| A CIBERSORTx-based immune-cell scoring system could independently predict prognosis of myelodysplastic syndrome patients. Blood advances 2021 Oct . Wang Yu-Hung, Hou Hsin-An, Lin Chien-Chin, Kuo Yuan-Yeh, Yao Chi-Yuan, Hsu Chia-Lung, Tseng Mei-Hsuan, Tsai Cheng-Hong, Peng Yen-Ling, Kao Chein-Jun, Chou Wen-Chien, Tien Hwei-Fa |
| Clinical significance of cytogenetic and molecular genetic abnormalities in 634 Chinese patients with myelodysplastic syndromes. Cancer medicine 2021 Feb . Yan Xuefen, Wang Lu, Jiang Lingxu, Luo Yingwan, Lin Peipei, Yang Wenli, Ren Yanling, Ma Liya, Zhou Xinping, Mei Chen, Ye Li, Xu Gaixiang, Xu Weilai, Yang Haiyang, Lu Chenxi, Jin Jie, Tong Hongy |
| [Correlation between U2AF1 Gene Mutation Characteristics and Clinical Manifestations and Prognosis in Patients with Myelodysplastic Syndrome]. Zhongguo shi yan xue ye xue za zhi 2020 Dec 28 (6): 1977-1984. Zhao Wen-Shu, Zhang Yin-Tian, Jiang Qian-Li, Liu Qi-Fa, Dai M |
| The prognostic impact of variant allele frequency (VAF) in TP53 mutant patients with MDS: A systematic review and meta-analysis. European journal of haematology 2020 Jul . Deng Jili, Wu Xia, Ling Yantao, Liu Xiaoyan, Zheng Xue, Ye Wu, Yuping Go |
| Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes. Blood advances 2020 Feb 4 (3): 482-495. Montalban-Bravo Guillermo, Kanagal-Shamanna Rashmi, Benton Christopher B, Class Caleb A, Chien Kelly S, Sasaki Koji, Naqvi Kiran, Alvarado Yesid, Kadia Tapan M, Ravandi Farhad, Daver Naval, Takahashi Koichi, Jabbour Elias, Borthakur Gautham, Pemmaraju Naveen, Konopleva Marina, Soltysiak Kelly A, Pierce Sherry R, Bueso-Ramos Carlos E, Patel Keyur P, Kantarjian Hagop, Garcia-Manero Guiller |
| Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7. Leukemia 2020 Feb . Crisà Elena, Kulasekararaj Austin G, Adema Vera, Such Esperanza, Schanz Julie, Haase Detlef, Shirneshan Katayoon, Best Steven, Mian Syed A, Kizilors Aytug, Cervera José, Lea Nicholas, Ferrero Dario, Germing Ulrich, Hildebrandt Barbara, Martínez Ana Belén Valencia, Santini Valeria, Sanz Guillermo F, Solé Francesc, Mufti Ghulam |
| Impact of mutational variant allele frequency on prognosis in myelodysplastic syndromes. American journal of cancer research 2020 10 (12): 4476-4487. Jiang Lingxu, Wang Lu, Shen Chuying, Zhu Shuanghong, Lang Wei, Luo Yingwan, Zhang Hua, Yang Wenli, Han Yueyuan, Ma Liya, Ren Yanling, Zhou Xinping, Mei Chen, Ye Li, Xu Weilai, Yang Haiyang, Lu Chenxi, Jin Jie, Tong Hongy |
| Combining gene variants with clinical characteristics improves outcome prediction in Chinese patients with myelodysplastic syndromes. Leukemia & lymphoma 2019 Dec 1-8. Yu Yan, Zhang Tongtong, Bao Xiebing, Wang Qinrong, Zhang Ling, Hong Yang, Zeng Zhao, Shen Hongjie, Wu Depei, Pan Jinlan, Liu Hong, Chen Suning, Sun Aini |
| Mutation status and burden can improve prognostic prediction of patients with lower-risk myelodysplastic syndromes. Cancer science 2019 Dec . Jiang Lingxu, Luo Yingwan, Zhu Shuanghong, Wang Lu, Ma Liya, Zhang Hua, Shen Chuying, Yang Wenli, Ren Yanling, Zhou Xinping, Mei Chen, Ye Li, Xu Weilai, Yang Haiyang, Lu Chenxi, Jin Jie, Tong Hongy |
| Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern. Blood advances 2019 Oct 3 (20): 3111-3122. Berger Gerbrig, Gerritsen Mylene, Yi Guoqiang, Koorenhof-Scheele Theresia N, Kroeze Leonie I, Stevens-Kroef Marian, Yoshida Kenichi, Shiraishi Yuichi, van den Berg Eva, Schepers Hein, Huls Geert, Mulder André B, Ogawa Seishi, Martens Joost H A, Jansen Joop H, Vellenga E |
| Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation. Annals of hematology 2019 Jul . Caballero Juan Carlos, Sánchez Barba Mercedes, Hernández Sánchez Jesús María, Such Esperanza, Janusz Kamila, Sanz Guillermo, Cabrero Mónica, Chillón Carmen, Cervera José, Hurtado Ana María, Jerez Andrés, Calderón Cabrera Cristina, Valcárcel David, Lumbreras Eva, Abáigar María, López Cadenas Félix, Hernández Rivas Jesús María, Del Cañizo María Consuelo, Díez Campelo Mar |
| Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki. Haematologica 2019 May . Taguchi Masataka, Mishima Hiroyuki, Shiozawa Yusuke, Hayashida Chisa, Kinoshita Akira, Nannya Yasuhito, Makishima Hideki, Horai Makiko, Matsuo Masatoshi, Sato Shinya, Itonaga Hidehiro, Kato Takeharu, Taniguchi Hiroaki, Imanishi Daisuke, Imaizumi Yoshitaka, Hata Tomoko, Takenaka Motoi, Moriuchi Yukiyoshi, Shiraishi Yuichi, Miyano Satoru, Ogawa Seishi, Yoshiura Koh-Ichiro, Miyazaki Yasus |
| TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia 2019 Jan . Haase Detlef, Stevenson Kristen E, Neuberg Donna, Maciejewski Jaroslaw P, Nazha Aziz, Sekeres Mikkael A, Ebert Benjamin L, Garcia-Manero Guillermo, Haferlach Claudia, Haferlach Torsten, Kern Wolfgang, Ogawa Seishi, Nagata Yasunobu, Yoshida Kenichi, Graubert Timothy A, Walter Matthew J, List Alan F, Komrokji Rami S, Padron Eric, Sallman David, Papaemmanuil Elli, Campbell Peter J, Savona Michael R, Seegmiller Adam, Adès Lionel, Fenaux Pierre, Shih Lee-Yung, Bowen David, Groves Michael J, Tauro Sudhir, Fontenay Michaela, Kosmider Olivier, Bar-Natan Michal, Steensma David, Stone Richard, Heuser Michael, Thol Felicitas, Cazzola Mario, Malcovati Luca, Karsan Aly, Ganster Christina, Hellström-Lindberg Eva, Boultwood Jacqueline, Pellagatti Andrea, Santini Valeria, Quek Lynn, Vyas Paresh, Tüchler Heinz, Greenberg Peter L, Bejar Rafael, |
| Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine. Oncotarget 2018 Apr 9 (27): 19342-19355. Cabezón Marta, Bargay Joan, Xicoy Blanca, García Olga, Borrás Josep, Tormo Mar, Marcé Sílvia, Pedro Carme, Valcárcel David, Jiménez Maria-José, Guàrdia Ramón, Palomo Laura, Brunet Salut, Vall-Llovera Ferran, Garcia Antoni, Feliu Evarist, Zamora Lurdes, |
| Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget 2018 Feb 9 (11): 9714-9727. Montalban-Bravo Guillermo, Takahashi Koichi, Patel Keyur, Wang Feng, Xingzhi Song, Nogueras Graciela M, Huang Xuelin, Pierola Ana Alfonso, Jabbour Elias, Colla Simona, Gañan-Gomez Irene, Borthakur Gautham, Daver Naval, Estrov Zeev, Kadia Tapan, Pemmaraju Naveen, Ravandi Farhad, Bueso-Ramos Carlos, Chamseddine Ali, Konopleva Marina, Zhang Jianhua, Kantarjian Hagop, Futreal Andrew, Garcia-Manero Guiller |
| Mutations and prognosis in myelodysplastic syndromes: karyotype-adjusted analysis of targeted sequencing in 300 consecutive cases and development of a genetic risk model. American journal of hematology 2018 Feb . Gangat Naseema, Mudireddy Mythri, Lasho Terra L, Finke Christy M, Nicolosi Maura, Szuber Natasha, Patnaik Mrinal M, Pardanani Animesh, Hanson Curtis A, Ketterling Rhett P, Tefferi Ayal |
| Targeted next-generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS-R. American journal of hematology 2017 Sep . Tefferi Ayalew, Lasho Terra L, Patnaik Mrinal M, Saeed Lyla, Mudireddy Mythri, Idossa Dame, Finke Christy, Ketterling Rhett P, Pardanani Animesh, Gangat Nasee |
| Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation. Blood 2017 Feb . Yoshizato Tetsuichi, Nannya Yasuhito, Atsuta Yoshiko, Shiozawa Yusuke, Iijima-Yamashita Yuka, Yoshida Kenichi, Shiraishi Yuichi, Suzuki Hiromichi, Nagata Yasunobu, Sato Yusuke, Kakiuchi Nobuyuki, Matsuo Keitaro, Onizuka Makoto, Kataoka Keisuke, Chiba Kenichi, Tanaka Hiroko, Ueno Hiroo, Nakagawa Masahiro M, Przychodzen Bartlomiej, Haferlach Claudia, Kern Wolfgang, Aoki Kosuke, Itonaga Hidehiro, Kanda Yoshinobu, Sekeres Mikkael A, Maciejewski Jaroslaw P, Haferlach Torsten, Miyazaki Yasushi, Horibe Keizo, Sanada Masashi, Miyano Satoru, Makishima Hideki, Ogawa Seis |
| Clinical Effects of Driver Somatic Mutations on the Outcomes of Patients With Myelodysplastic Syndromes Treated With Allogeneic Hematopoietic Stem-Cell Transplantation. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016 Sep . Della Porta Matteo G, Gallì Anna, Bacigalupo Andrea, Zibellini Silvia, Bernardi Massimo, Rizzo Ettore, Allione Bernardino, van Lint Maria Teresa, Pioltelli Pietro, Marenco Paola, Bosi Alberto, Voso Maria Teresa, Sica Simona, Cuzzola Mariella, Angelucci Emanuele, Rossi Marianna, Ubezio Marta, Malovini Alberto, Limongelli Ivan, Ferretti Virginia V, Spinelli Orietta, Tresoldi Cristina, Pozzi Sarah, Luchetti Silvia, Pezzetti Laura, Catricalà Silvia, Milanesi Chiara, Riva Alberto, Bruno Benedetto, Ciceri Fabio, Bonifazi Francesca, Bellazzi Riccardo, Papaemmanuil Elli, Santoro Armando, Alessandrino Emilio P, Rambaldi Alessandro, Cazzola Mar |
| Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome. Oncotarget 2016 Jul . Jung Seung-Hyun, Kim Yoo-Jin, Yim Seon-Hee, Kim Hye-Jung, Kwon Yong-Rim, Hur Eun-Hye, Goo Bon-Kwan, Choi Yun-Suk, Lee Sug Hyung, Chung Yeun-Jun, Lee Je-Hw |
| TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes. Oncotarget 2016 May . Belickova Monika, Vesela Jitka, Jonasova Anna, Pejsova Barbora, Votavova Hana, Merkerova Michaela Dostalova, Zemanova Zuzana, Brezinova Jana, Mikulenkova Dana, Lauermannova Marie, Valka Jan, Michalova Kyra, Neuwirtova Radana, Cermak Jarosl |
| Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes. Leukemia research 2016 Jan 42 7-12. Svobodova Karla, Zemanova Zuzana, Lhotska Halka, Novakova Milena, Podskalska Lucie, Belickova Monika, Brezinova Jana, Sarova Iveta, Izakova Silvia, Lizcova Libuse, Berkova Adela, Siskova Magda, Jonasova Anna, Cermak Jaroslav, Michalova Ky |
| Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes. PloS one 2016 11 (10): e0164370. Abáigar María, Robledo Cristina, Benito Rocío, Ramos Fernando, Díez-Campelo María, Hermosín Lourdes, Sánchez-Del-Real Javier, Alonso Jose M, Cuello Rebeca, Megido Marta, Rodríguez Juan N, Martín-Núñez Guillermo, Aguilar Carlos, Vargas Manuel, Martín Ana A, García Juan L, Kohlmann Alexander, Del Cañizo M Consuelo, Hernández-Rivas Jesús |
| Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases. Leukemia research 2015 Mar 39 (3): 348-54. Ok Chi Young, Patel Keyur P, Garcia-Manero Guillermo, Routbort Mark J, Fu Bin, Tang Guilin, Goswami Maitrayee, Singh Rajesh, Kanagal-Shamanna Rashmi, Pierce Sherry A, Young Ken H, Kantarjian Hagop M, Medeiros L Jeffrey, Luthra Rajyalakshmi, Wang Sa |
| MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation. Human pathology 2015 Jan 46 (1): 65-73. Tang Guilin, DiNardo Courtney, Zhang Liping, Ravandi Farhad, Khoury Joseph D, Huh Yang O, Muzzafar Tariq, Medeiros L Jeffrey, Wang Sa A, Bueso-Ramos Carlos |
| The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes. Blood cancer journal 2015 5 e291. McGraw K L, Zhang L M, Rollison D E, Basiorka A A, Fulp W, Rawal B, Jerez A, Billingsley D L, Lin H-Y, Kurtin S E, Yoder S, Zhang Y, Guinta K, Mallo M, Solé F, Calasanz M J, Cervera J, Such E, González T, Nevill T J, Haferlach T, Smith A E, Kulasekararaj A, Mufti G, Karsan A, Maciejewski J P, Sokol L, Epling-Burnette P K, Wei S, List A |
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- Page last updated:Aug 10, 2022
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