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| Prognostic role of TNF alpha, LT alpha, MDR1 and codon 72 Tp53 gene polymorphisms on multiple myeloma Egyptian patients. Leukemia research 2022 Jun 117 106854. Hegazi Heba M, Elghonemy M S, El-Baiomy M A, Soliman Eman A, Abdel-Hady Elsayed |
| Clonal and subclonal TP53 molecular impairment is associated with prognosis and progression in multiple myeloma. Blood cancer journal 2022 01 12 (1): 15. Martello M, Poletti A, Borsi E, Solli V, Dozza L, Barbato S, Zamagni E, Tacchetti P, Pantani L, Mancuso K, Vigliotta I, Rizzello I, Rocchi S, Armuzzi S, Testoni N, Marzocchi G, Martinelli G, Cavo M, Terragna |
| Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia 2022 6 36 (7): 1887-1897. Misund Kristine, Hofste Op Bruinink Davine, Coward Eivind, Hoogenboezem Remco M, Rustad Even Holth, Sanders Mathijs A, Rye Morten, Sponaas Anne-Marit, van der Holt Bronno, Zweegman Sonja, Hovig Eivind, Meza-Zepeda Leonardo A, Sundan Anders, Myklebost Ola, Sonneveld Pieter, Waage Ande |
| Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma. Blood advances 2022 10 7 (2): 236-245. Barnell Erica K, Skidmore Zachary L, Newcomer Kenneth F, Chavez Monique, Campbell Katie M, Cotto Kelsy C, Spies Nicholas C, Ruzinova Marianna B, Wang Tianjiao, Abro Brooj, Kreisel Friederike, Parikh Bijal A, Duncavage Eric J, Frater John L, Lee Yi-Shan, Hassan Anjum, King Justin A, Kohnen Daniel R, Fiala Mark A, Welch John S, Uy Geoffrey L, Vij Kiran, Vij Ravi, Griffith Malachi, Griffith Obi L, Wartman Lukas |
| Genomic characterization of functional high-risk multiple myeloma patients. Blood cancer journal 2022 2 12 (1): 24. Soekojo Cinnie Yentia, Chung Tae-Hoon, Furqan Muhammad Shaheryar, Chng Wee J |
| Identification of clinical implications and potential prognostic models of chromatin regulator mutations in multiple myeloma. Clinical epigenetics 2022 7 14 (1): 93. Zhang Lina, Zhang Run, Wang Jing, Chen Ying, Qiao Chun, Shi Qinglin, Jin Yuanyuan, Shen Xuxing, Li Jianyong, Chen Liju |
| Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma. Blood 2022 10 141 (6): 620-633. Ansari-Pour Naser, Samur Mehmet, Flynt Erin, Gooding Sarah, Towfic Fadi, Stong Nicholas, Estevez Maria Ortiz, Mavrommatis Konstantinos, Walker Brian, Morgan Gareth, Munshi Nikhil, Avet-Loiseau Herve, Thakurta Anj |
| Clinical Significance of TP53 Abnormalities in Newly Diagnosed Multiple Myeloma. Turkish journal of haematology : official journal of Turkish Society of Haematology 2021 5 38 (4): 246-253. Ye Fang, Wang Tongtong, Liu Aijun, Li Yanchen, Li Ningning, Wang Huan, Chen Wenmi |
| Genetic profile of primary plasma cell leukemia in Korea: comparison with plasma cell myeloma. Leukemia & lymphoma 2021 10 63 (2): 385-394. Lee Youngeun, Yun Jiwon, Jeong Dajeong, Ryu Sohee, Kwon Seok Ryun, Yun Hongseok, Kim Sung Min, Park Jae Hyeon, Lee Dong So |
| The clonal evolution during long-term clinical course of multiple myeloma. International journal of hematology 2020 Aug . Mishima Yuko, Mishima Yuji, Shirouchi Yuko, Nishimura Noriko, Yokoyama Masahiro, Okabe Takashi, Inoue Norihito, Uryu Hideki, Fukuta Takanori, Hatake Kiyohiko, Terui Yasuhi |
| Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nature communications 2020 6 11 (1): 2996. Mouhieddine Tarek H, Sperling Adam S, Redd Robert, Park Jihye, Leventhal Matthew, Gibson Christopher J, Manier Salomon, Nassar Amin H, Capelletti Marzia, Huynh Daisy, Bustoros Mark, Sklavenitis-Pistofidis Romanos, Tahri Sabrin, Hornburg Kalvis, Dumke Henry, Itani Muhieddine M, Boehner Cody J, Liu Chia-Jen, AlDubayan Saud H, Reardon Brendan, Van Allen Eliezer M, Keats Jonathan J, Stewart Chip, Mehr Shaadi, Auclair Daniel, Schlossman Robert L, Munshi Nikhil C, Anderson Kenneth C, Steensma David P, Laubach Jacob P, Richardson Paul G, Ritz Jerome, Ebert Benjamin L, Soiffer Robert J, Trippa Lorenzo, Getz Gad, Neuberg Donna S, Ghobrial Irene |
| del(17p) without TP53 mutation confers a poor prognosis in intensively treated newly diagnosed patients with multiple myeloma. Blood 2020 10 137 (9): 1192-1195. Corre Jill, Perrot Aurore, Caillot Denis, Belhadj Karim, Hulin Cyrille, Leleu Xavier, Mohty Mohamad, Facon Thierry, Buisson Laure, Do Souto Laura, Lannes Romain, Dufrechou Stephanie, Prade Naïs, Orsini-Piocelle Frederique, Voillat Laurent, Jaccard Arnaud, Karlin Lionel, Macro Margaret, Brechignac Sabine, Dib Mamoun, Sanhes Laurence, Fontan Jean, Clement-Filliatre Lauriane, Marolleau Jean-Pierre, Minvielle Stephane, Moreau Philippe, Avet-Loiseau Her |
| Early Relapse Risk in Patients with Newly Diagnosed Multiple Myeloma Characterized by Next-generation Sequencing. Clinical cancer research : an official journal of the American Association for Cancer Research 2020 7 26 (18): 4832-4841. D'Agostino Mattia, Zaccaria Gian Maria, Ziccheddu Bachisio, Rustad Even H, Genuardi Elisa, Capra Andrea, Oliva Stefania, Auclair Daniel, Yesil Jennifer, Colucci Paola, Keats Jonathan J, Gambella Manuela, Bringhen Sara, Larocca Alessandra, Boccadoro Mario, Bolli Niccolò, Maura Francesco, Gay Frances |
| Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 5 38 (21): 2380-2389. Bustoros Mark, Sklavenitis-Pistofidis Romanos, Park Jihye, Redd Robert, Zhitomirsky Benny, Dunford Andrew J, Salem Karma, Tai Yu-Tzu, Anand Shankara, Mouhieddine Tarek H, Chavda Selina J, Boehner Cody, Elagina Liudmila, Neuse Carl Jannes, Cha Justin, Rahmat Mahshid, Taylor-Weiner Amaro, Van Allen Eliezer, Kumar Shaji, Kastritis Efstathis, Leshchiner Ignaty, Morgan Elizabeth A, Laubach Jacob, Casneuf Tineke, Richardson Paul, Munshi Nikhil C, Anderson Kenneth C, Trippa Lorenzo, Aguet François, Stewart Chip, Dimopoulos Meletios-Athanasios, Yong Kwee, Bergsagel P Leif, Manier Salomon, Getz Gad, Ghobrial Irene |
| EZH2 Overexpression in Multiple Myeloma: Prognostic Value, Correlation With Clinical Characteristics, and Possible Mechanisms. Clinical lymphoma, myeloma & leukemia 2019 Aug . Goldsmith Scott R, Fiala Mark A, O'Neal Julie, Souroullas George P, Toama Wael, Vij Ravi, Schroeder Mark |
| Genetic and transcriptional landscape of plasma cells in POEMS syndrome. Leukemia 2019 Jan . Nagao Yuhei, Mimura Naoya, Takeda June, Yoshida Kenichi, Shiozawa Yusuke, Oshima Motohiko, Aoyama Kazumasa, Saraya Atsunori, Koide Shuhei, Rizq Ola, Hasegawa Yoshinori, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Nishijima Dai, Isshiki Yusuke, Kayamori Kensuke, Kawajiri-Manako Chika, Oshima-Hasegawa Nagisa, Tsukamoto Shokichi, Mitsukawa Shio, Takeda Yusuke, Ohwada Chikako, Takeuchi Masahiro, Iseki Tohru, Misawa Sonoko, Miyano Satoru, Ohara Osamu, Yokote Koutaro, Sakaida Emiko, Kuwabara Satoshi, Sanada Masashi, Iwama Atsushi, Ogawa Seishi, Nakaseko Chia |
| High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma. Blood 2019 Jan . Thakurta Anjan, Ortiz Maria, Blecua Pedro, Towfic Fadi, Corre Jill, Serbina Natalya V, Flynt Erin, Yu Zhinuan, Yang Zhihong, Palumbo Antonio, Dimopoulos Meletios A, Gutierrez Norma C, Goldschmidt Hartmut, Sonneveld Pieter, Avet-Loiseau Her |
| Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53. Oncotarget 2019 Jan 10 (7): 732-737. Ashby Cody, Tytarenko Ruslana G, Wang Yan, Weinhold Niels, Johnson Sarah K, Bauer Michael, Wardell Christopher P, Schinke Carolina, Thanendrarajan Sharmilan, Zangari Mauricio, van Rhee Frits, Davies Faith E, Sawyer Jeffrey R, Morgan Gareth J, Walker Brian |
| A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5. Blood cancer journal 2018 3 8 (3): 35. White Brian S, Lanc Irena, O'Neal Julie, Gupta Harshath, Fulton Robert S, Schmidt Heather, Fronick Catrina, Belter Edward A, Fiala Mark, King Justin, Ahmann Greg J, DeRome Mary, Mardis Elaine R, Vij Ravi, DiPersio John F, Levy Joan, Auclair Daniel, Tomasson Michael |
| Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse. Molecular cytogenetics 2018 11 7. Smetana Jan, Oppelt Jan, Štork Martin, Pour Lud?k, Kuglík Pe |
| Subclonal TP53 copy number is associated with prognosis in multiple myeloma. Blood 2018 10 132 (23): 2465-2469. Shah Vallari, Johnson David C, Sherborne Amy L, Ellis Sidra, Aldridge Frances M, Howard-Reeves Julie, Begum Farzana, Price Amy, Kendall Jack, Chiecchio Laura, Savola Suvi, Jenner Matthew W, Drayson Mark T, Owen Roger G, Gregory Walter M, Morgan Gareth J, Davies Faith E, Houlston Richard S, Cook Gordon, Cairns David A, Jackson Graham, Kaiser Martin F, |
| Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases. PLoS genetics 2017 Nov 13 (11): e1007087. Manojlovic Zarko, Christofferson Austin, Liang Winnie S, Aldrich Jessica, Washington Megan, Wong Shukmei, Rohrer Daniel, Jewell Scott, Kittles Rick A, Derome Mary, Auclair Daniel, Craig David Wesley, Keats Jonathan, Carpten John |
| Mutational landscape reflects the biological continuum of plasma cell dyscrasias. Blood cancer journal 2017 Feb 7 (2): e537. Rossi A, Voigtlaender M, Janjetovic S, Thiele B, Alawi M, März M, Brandt A, Hansen T, Radloff J, Schön G, Hegenbart U, Schönland S, Langer C, Bokemeyer C, Binder |
| The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma. Oncotarget 2017 Feb . Stein Caleb K, Pawlyn Charlotte, Chavan Shweta, Rasche Leo, Weinhold Niels, Corken Adam, Buros Amy, Sonneveld Pieter, Jackson Graham H, Landgren Ola, Mughal Tariq, He Jie, Barlogie Bart, Leif Bergsagel P, Davies Faith E, Walker Brian A, Morgan Gareth |
| Single nucleotide polymorphisms in TP53 but not KRAS or MDM2 are predictive of clinical outcome in multiple myeloma treated with high-dose melphalan and autologous stem cell support. Leukemia & lymphoma 2015 Sep 1-11. Gebauer Niklas, Biersack Harald, Czerwinska Ann-Cathrin, Schemme Janina, Hardel Tim Tristan, Bernard Veronica, Rades Dirk, Lehnert Hendrik, Luley Kim Barbara, Thorns Christo |
| Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma. Oncotarget 2014 Oct 5 (20): 9798-810. Kristensen Lasse Sommer, Asmar Fazila, Dimopoulos Konstantinos, Nygaard Mette Kathrine, Aslan Derya, Hansen Jakob Werner, Ralfkiaer Elisabeth, Grønbæk Kirst |
| Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy. Cancer cell 2014 Jan 25 (1): 91-101. Lohr Jens G, Stojanov Petar, Carter Scott L, Cruz-Gordillo Peter, Lawrence Michael S, Auclair Daniel, Sougnez Carrie, Knoechel Birgit, Gould Joshua, Saksena Gordon, Cibulskis Kristian, McKenna Aaron, Chapman Michael A, Straussman Ravid, Levy Joan, Perkins Louise M, Keats Jonathan J, Schumacher Steven E, Rosenberg Mara, , Getz Gad, Golub Todd |
| Berberine induces apoptosis in human multiple myeloma cell line U266 through hypomethylation of p53 promoter. Cell biology international 2014 5 38 (5): 563-70. Qing Yanwei, Hu Haiyan, Liu Yuan, Feng Tao, Meng Wei, Jiang Ling, Sun Yongning, Yao Ya |
| Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles. American journal of hematology 2012 Sep . Mosca L, Musto P, Todoerti K, Barbieri M, Agnelli L, Fabris S, Tuana G, Lionetti M, Bonaparte E, Sirchia SM, Grieco V, Bianchino G, D'Auria F, Statuto T, Mazzoccoli C, De Luca L, Petrucci MT, Morabito F, Offidani M, Di Raimondo F, Falcone A, Caravita T, Omedè P, Boccadoro M, Palumbo A, Neri A |
| Epigenetic inactivation of the MIR34B/C in multiple myeloma. Blood 2011 10 118 (22): 5901-4. Wong Kwan Yeung, Yim Rita Lok Hay, So Chi Chiu, Jin Dong-Yan, Liang Raymond, Chim Chor Sa |
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- Page last updated:Mar 29, 2023
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