HuGE Literature Finder
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| MTHFR Polymorphism Is Associated With Severe Methotrexate-Induced Toxicity in Osteosarcoma Treatment. Frontiers in oncology 2022 1 11 781386. Zhang Wenchao, Liu Zhongyue, Yang Zhimin, Feng Chengyao, Zhou Xiaowen, Tu Chao, Li Zhiho |
| Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study. Journal of clinical pharmacy and therapeutics 2021 Aug . Gong Yan, Luo Li, Wang Liu, Chen Jun, Chen Fen, Ma Yuanyuan, Xu Zhen, Sun Yiqi, Luo Lin, Shi Chen, Li Xinga |
| Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis. Critical reviews in oncology/hematology 2021 Mar 103312. Maagdenberg Hedy, Oosterom Natanja, Zanen Jolanda, Gemmati Donato, Windsor Rachael E, Heil Sandra G, Esperón Patricia, Jabeen Shakila, Ruiz-Argüelles Guillermo J, Zolk Oliver, Hoerning Susanne, Sleurs Charlotte, Lopéz-Lopéz Elixabet, Moreno-Galván Mónica, van den Heuvel-Eibrink Marry M, Maitland-van der Zee Anke H, Carleton Bruce |
| Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia. Journal of pediatric hematology/oncology 2021 2 43 (8): e1173-e1176. Kudo Ko, Sato Tomohiko, Takahashi Yuka, Yuzawa Kentaro, Kobayashi Akie, Kamio Takuya, Sasaki Shinya, Shimada Jun, Otani Katsuki, Tusjimoto Shinichi, Kato Motohiro, Toki Tsutomu, Terui Kiminori, Ito Etsu |
| Influence of Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphism on High-Dose Methotrexate-Related Toxicities in Pediatric Non-Hodgkin Lymphoma Patients. Frontiers in oncology 2021 11 598226. Lu Suying, Zhu Xiaoqin, Li Wei, Chen Huimou, Zhou Dalei, Zhen Zijun, Sun Feifei, Huang Junting, Zhu Jia, Wang Juan, Zhang Yizhuo, Sun Xiaof |
| The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis. Frontiers in pharmacology 2021 12 757464. Song Zaiwei, Hu Yang, Liu Shuang, Jiang Dan, Yi Zhanmiao, Benjamin Mason M, Zhao Rongshe |
| Influence of plasma methotrexate level and MTHFR genotype in Korean paediatric patients with acute lymphoblastic leukaemia. Journal of chemotherapy (Florence, Italy) 2020 May 1-9. Chae Hyojin, Kim Myungshin, Choi Sun Hee, Kim Seong-Koo, Lee Jae-Wook, Chung Nack-Gyun, Cho Bin, Kim Yongg |
| Pharmacogenetic Variants in MTHFR Gene are Significant Predictors of Methotrexate Toxicities in Bangladeshi Patients With Acute Lymphoblastic Leukemia. Clinical lymphoma, myeloma & leukemia 2019 Dec . Zahra Fatema Tuz, Nahid Noor Ahmed, Islam Md Reazul, Al-Mamun Mir Md Abdullah, Apu Mohd Nazmul Hasan, Nahar Zabun, Kabir Amin Lutful, Biswas Subrata K, Ahmed Maizbha Uddin, Islam Mohammad Safiqul, Hasnat Ab |
| MTHFR variant is associated with high-dose methotrexate-induced toxicity in the Chinese osteosarcoma patients. Journal of bone oncology 2018 Nov 13 143-147. Xu Leilei, Wang Lujun, Xue Bingchuan, Wang Shoufe |
| DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer. Cancer chemotherapy and pharmacology 2017 Nov . Nahid Noor Ahmed, Apu Mohd Nazmul Hasan, Islam Md Reazul, Shabnaz Samia, Chowdhury Surid Mohammad, Ahmed Maizbha Uddin, Nahar Zabun, Islam Md Siddiqul, Islam Mohammad Safiqul, Hasnat Ab |
| Associations between the C677T and A1298C polymorphisms of MTHFR and the toxicity of methotrexate in childhood malignancies: a meta-analysis. The pharmacogenomics journal 2017 Jul . Zhu C, Liu Y W, Wang S Z, Li X L, Nie X L, Yu X T, Zhao L B, Wang X |
| The role of the MTHFR C677T polymorphism in methotrexate-induced toxicity in pediatric osteosarcoma patients. Pharmacogenomics 2017 Jun . Lambrecht Loes, Sleurs Charlotte, Labarque Veerle, Dhooge Catharina, Laenen Annouschka, Sinnaeve Friedl, Renard Marleen, Uyttebroeck An |
| Methotrexate elimination and toxicity: MTHFR 677C>T polymorphism in patients with primary CNS lymphoma treated with high-dose methotrexate. Hematological oncology 2016 Oct . Choi Yun Jung, Park Hyangmin, Lee Ji Sung, Lee Ju-Yeon, Kim Shin, Kim Tae Won, Park Jung Sun, Kim Jeong Eun, Yoon Dok Hyun, Suh Cheolw |
| Mexican Childhood Acute Lymphoblastic Leukemia: A Pilot Study of the MDR1 and MTHFR Gene Polymorphisms and Their Associations with Clinical Outcomes. Genetic testing and molecular biomarkers 2016 Oct 20 (10): 597-602. Ramírez-Pacheco Arturo, Moreno-Guerrero Selene, Alamillo Ilse, Medina-Sanson Aurora, Lopez Briseida, Moreno-Galván Moni |
| Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses. Cancer chemotherapy and pharmacology 2016 Jul 78 (1): 27-39. Campbell Jared M, Bateman Emma, Stephenson Matthew D, Bowen Joanne M, Keefe Dorothy M, Peters Micah D |
| MTHFR gene polymorphisms and methotrexate toxicity in adult patients with hematological malignancies: a meta-analysis. Pharmacogenomics 2016 Jun . Zhao Ming, Liang Liang, Ji Liwei, Chen Di, Zhang Yatong, Zhu Yuanchao, Ongaro Aless |
| Influence of genetic polymorphisms in the folate pathway on toxicity after high-dose methotrexate treatment in pediatric osteosarcoma. Blood research 2016 Mar 51 (1): 50-7. Park Jeong A, Shin Hee You |
| Role of folate status and methylenetetrahydrofolate reductase genotype on the toxicity and outcome of induction chemotherapy in children with acute lymphoblastic leukemia. Leukemia & lymphoma 2015 May 56 (5): 1379-84. Roy Moulik Nirmalya, Kumar Archana, Agrawal Suraksha, Awasthi Shally, Mahdi Abbas Ali, Kumar Ashuto |
| Effect of polymorphisms within methotrexate pathway genes on methotrexate toxicity and plasma levels in adults with hematological malignancies. Pharmacogenomics 2014 Aug 15 (11): 1479-94. Suthandiram Sujatha, Gan Gin-Gin, Zain Shamsul Mohd, Bee Ping-Chong, Lian Lay-Hoong, Chang Kian-Meng, Ong Tee-Chuan, Mohamed Zahur |
| MTHFR C677T polymorphism: association with lymphoid neoplasm and effect on methotrexate therapy. European journal of haematology 2014 Jul 93 (1): 63-9. Ayad Mona W, El Naggar Amel A, El Naggar Mosta |
| Impact of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on methotrexate-induced toxicities in acute lymphoblastic leukemia: a meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012 Oct 33 (5): 1445-54. Yang Lin, Hu Xin, Xu Luha |
| The effect of folinic acid on methylenetetrahydrofolate reductase polymorphisms in methotrexate-treated allogeneic hematopoietic stem cell transplants. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012 May 18 (5): 722-30. Murphy Nicholas M, Diviney Mary, Szer Jeff, Bardy Peter, Grigg Andrew, Hoyt Rosemary, King-Kallimanis Belinda, Holdsworth Rhonda, McCluskey James, Tait Brian |
| Relationship between antimetabolite toxicity and pharmacogenetics in Turkish cancer patients. Asian Pacific journal of cancer prevention : APJCP 2012 13 (4): 1553-6. Dogan Mutlu, Karabulut Halil G, Tukun Ajlan, Demirkazik Ahmet, Utkan Gungor, Yalcin Bulent, Dincol Dilek, Akbulut Hakan, Icli Fik |
| Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. British journal of cancer 2011 Nov 105 (11): 1654-62. Thomas F, Motsinger-Reif A A, Hoskins J M, Dvorak A, Roy S, Alyasiri A, Myerson R J, Fleshman J W, Tan B R, McLeod H |
| Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma. European journal of clinical pharmacology 2011 Oct 67 (10): 993-1006. Faganel Kotnik Barbara, Grabnar Iztok, Bohanec Grabar Petra, Dolžan Vita, Jazbec Jan |
| Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2010 Jan 21 (1): 28-34. Tantawy Azza A G, El-Bostany Eman A, Adly Amira A M, Abou El Asrar Mohammed, El-Ghouroury Eman A, Abdulghaffar Esmat |
| Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia. Leukemia 2009 Mar 23 (3): 545-56. Rocha V, Porcher R, Fernandes J F, Filion A, Bittencourt H, Silva W, Vilela G, Zanette D L, Ferry C, Larghero J, Devergie A, Ribaud P, Skvortsova Y, Tamouza R, Gluckman E, Socie G, Zago M |
| Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 May 26 (13): 2131-8. Schwab Matthias, Zanger Ulrich M, Marx Claudia, Schaeffeler Elke, Klein Kathrin, Dippon Jürgen, Kerb Reinhold, Blievernicht Julia, Fischer Joachim, Hofmann Ute, Bokemeyer Carsten, Eichelbaum Michel, |
| ABCG2 polymorphism, age and leukocyte count may contribute to oral mucositis in oncopediatric patients. Brazilian dental journal 0 32 (2): 14-26. Viana Filho José Maria Chagas, Coêlho Marina de Castro, Ribeiro Isabella Lima Arrais, Persuhn Darlene Camati, Valença Ana Maria Gondim, Oliveira Naila Francis Paulo |
| Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population. Technology in cancer research & treatment 0 20 1533033821995288. Huang Shuang, Jin Lin, Yang Jing, Duan Long Yan, Zhang Meng, Zhou Ju Chun, Zhang Hong Yo |
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- Page last updated:Mar 22, 2023
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