HuGE Literature Finder
Records 1-30
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Next-generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage-Multicenter experience.
Head & neck 2019 Nov . Moore Assaf, Bar Yael, Maurice-Dror Corinne, Ospovat Inna, Sarfaty Michal, Korzets Yasmin, Goldvaser Hadar, Gordon Noa, Billan Salem, Gutfeld Orit, Popovtzer Ar |
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Mutation profiling of cancer drivers in Brazilian colorectal cancer.
Scientific reports 2019 Sep 9 (1): 13687. Dos Santos Wellington, Sobanski Thais, de Carvalho Ana Carolina, Evangelista Adriane Feijó, Matsushita Marcus, Berardinelli Gustavo Nóriz, de Oliveira Marco Antonio, Reis Rui Manuel, Guimarães Denise Peixo |
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High prevalence of the MLH1 V384D germline mutation in patients with HER2-positive luminal B breast cancer.
Scientific reports 2019 Jul 9 (1): 10966. Lee Seung Eun, Lee Hye Seung, Kim Kyoung-Yeon, Park Jung-Hoon, Roh Hanseong, Park Ha Young, Kim Wan-Se |
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Molecular profiling and molecular classification of endometrioid ovarian carcinomas.
Gynecologic oncology 2019 Jul . Cybulska Paulina, Paula Arnaud Da Cruz, Tseng Jill, Leitao Mario M, Bashashati Ali, Huntsman David G, Nazeran Tayyebeh M, Aghajanian Carol, Abu-Rustum Nadeem R, DeLair Deborah F, Shah Sohrab P, Weigelt Brit |
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Calcium intake and colon cancer risk subtypes by tumor molecular characteristics.
Cancer causes & control : CCC 2019 Apr . Keum NaNa, Liu Li, Hamada Tsuyoshi, Qian Zhi Rong, Nowak Jonathan A, Cao Yin, da Silva Annacarolina, Kosumi Keisuke, Song Mingyang, Nevo Daniel, Wang Molin, Chan Andrew T, Meyerhardt Jeffrey A, Fuchs Charles S, Wu Kana, Ogino Shuji, Nishihara Reiko, Zhang Xueho |
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Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer.
Journal of translational medicine 2019 Apr 17 (1): 137. Isnaldi Edoardo, Garuti Anna, Cirmena Gabriella, Scabini Stefano, Rimini Edoardo, Ferrando Lorenzo, Lia Michela, Murialdo Roberto, Tixi Lucia, Carminati Enrico, Panaro Andrea, Gallo Maurizio, Grillo Federica, Mastracci Luca, Repetto Lazzaro, Fiocca Roberto, Romairone Emanuele, Zoppoli Gabriele, Ballestrero Alber |
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Associations of PIK3CA mutations with clinical features and prognosis in gastric cancer.
Future oncology (London, England) 2019 Mar . Shen Xiaobing, Zhao Ying, Chen Xiaowei, Sun Haixiang, Liu Mengqi, Zhang Wenwen, Jiang Fei, Li Pengf |
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Clinicopathological and molecular differences in colorectal cancer according to location.
The International journal of biological markers 2019 Mar 1724600818807164. Hsu Yu-Lun, Lin Chun-Chi, Jiang Jeng-Kai, Lin Hung-Hsin, Lan Yuan-Tzu, Wang Huann-Sheng, Yang Shung-Haur, Chen Wei-Shone, Lin Tzu-Chen, Lin Jen-Kou, Lin Pei-Ching, Chang Shih-Chi |
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Frequent CTNNB1 or PIK3CA Mutations Occurred in Endometrial Endometrioid Adenocarcinoma With High Levels of Microsatellite Instability and Loss of MSH2/MSH6 Expression.
Applied immunohistochemistry & molecular morphology : AIMM 2019 Feb . Huang Hsien-Neng, Kuo Chun-Wei, Lin Ming-Chieh, Mao Tsui-Lien, Kuo Kuan-Ti |
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Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Journal of clinical pathology 2019 03 72 (3): 263-264. Susanti Susanti, Fadhil Wakkas, Murtaza Shamayal, Hassall James C, Ebili Henry O, Oniscu Anca, Ilyas Mohamm |
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First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Clinical drug investigation 2018 Jun 38 (6): 553-562. Moiseyenko Vladimir M, Moiseyenko Fedor V, Yanus Grigoriy A, Kuligina Ekatherina Sh, Sokolenko Anna P, Bizin Ilya V, Kudriavtsev Alexey A, Aleksakhina Svetlana N, Volkov Nikita M, Chubenko Vyacheslav A, Kozyreva Kseniya S, Kramchaninov Mikhail M, Zhuravlev Alexandr S, Shelekhova Kseniya V, Pashkov Denis V, Ivantsov Alexandr O, Venina Aigul R, Sokolova Tatyana N, Preobrazhenskaya Elena V, Mitiushkina Natalia V, Togo Alexandr V, Iyevleva Aglaya G, Imyanitov Evgeny |
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PIK3CA mutation in gastric cancer and the role of microsatellite instability status in mutations of exons 9 and 20 of the PIK3CA gene.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2018 Jun . Polom Karol, Marrelli Daniele, Roviello Giandomenico, Pascale Valeria, Voglino Costantino, Vindigni Carla, Generali Daniele, Roviello Fran |
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Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Journal of the National Cancer Institute 2018 Apr . Loree Jonathan M, Bailey Ann M, Johnson Amber M, Yu Yao, Wu Wenhui, Bristow Christopher A, Davis Jennifer S, Shaw Kenna R, Broaddus Russell, Banks Kimberly C, Lanman Richard B, Meric-Bernstam Funda, Overman Michael J, Kopetz Scott, Raghav Kanw |
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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Cancer cell 2018 Jan 33 (1): 125-136.e3. Yaeger Rona, Chatila Walid K, Lipsyc Marla D, Hechtman Jaclyn F, Cercek Andrea, Sanchez-Vega Francisco, Jayakumaran Gowtham, Middha Sumit, Zehir Ahmet, Donoghue Mark T A, You Daoqi, Viale Agnes, Kemeny Nancy, Segal Neil H, Stadler Zsofia K, Varghese Anna M, Kundra Ritika, Gao Jianjiong, Syed Aijazuddin, Hyman David M, Vakiani Efsevia, Rosen Neal, Taylor Barry S, Ladanyi Marc, Berger Michael F, Solit David B, Shia Jinru, Saltz Leonard, Schultz Nikola |
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Comprehensive analysis of cancers of unknown primary for the biomarkers of response to immune checkpoint blockade therapy.
European journal of cancer (Oxford, England : 1990) 2018 05 94 179-186. Gatalica Zoran, Xiu Joanne, Swensen Jeff, Vranic Sem |
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Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Molecular carcinogenesis 2017 Dec . Sugai Tamotsu, Takahashi Yayoi, Eizuka Makoto, Sugimoto Ryo, Fujita Yasuko, Habano Wataru, Otsuka Kouki, Sasaki Akira, Yamamoto Eiichiro, Matsumoto Takayuki, Suzuki Hiro |
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Clinical Targeted Next-Generation Sequencing Shows Increased Mutational Load in Endometrioid-type Endometrial Adenocarcinoma With Deficient DNA Mismatch Repair.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2017 Oct . Lee Paul J, McNulty Samantha, Duncavage Eric J, Heusel Jonathan W, Hagemann Ian |
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Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.
Cancer 2017 Sep 123 (17): 3261-3268. Le Gallo Matthieu, Rudd Meghan L, Urick Mary Ellen, Hansen Nancy F, Zhang Suiyuan, , Lozy Fred, Sgroi Dennis C, Vidal Bel August, Matias-Guiu Xavier, Broaddus Russell R, Lu Karen H, Levine Douglas A, Mutch David G, Goodfellow Paul J, Salvesen Helga B, Mullikin James C, Bell Daphne |
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Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis.
International journal of molecular sciences 2017 Aug 18 (9): . Balc'h Eric Le, Grandin Nathalie, Demattei Marie-Véronique, Guyétant Serge, Tallet Anne, Pagès Jean-Christophe, Ouaissi Mehdi, Lecomte Thierry, Charbonneau Mich |
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Genomic Profiling of Small-Bowel Adenocarcinoma.
JAMA oncology 2017 Jun . Schrock Alexa B, Devoe Craig E, McWilliams Robert, Sun James, Aparicio Thomas, Stephens Philip J, Ross Jeffrey S, Wilson Richard, Miller Vincent A, Ali Siraj M, Overman Michael |
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PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer.
Oncotarget 2017 Jun . Kim Ji-Won, Lee Hye Seung, Nam Kyung Han, Ahn Soyeon, Kim Jin Won, Ahn Sang-Hoon, Park Do Joong, Kim Hyung-Ho, Lee Keun-Wo |
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Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar 39 (3): 1010428317692246. Kleist Britta, Meurer Thuja, Poetsch Micae |
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Molecular Testing for Gastrointestinal Cancer.
Journal of pathology and translational medicine 2017 Feb . Lee Hye Seung, Kim Woo Ho, Kwak Yoonjin, Koh Jiwon, Bae Jeong Mo, Kim Kyoung-Mee, Chang Mee Soo, Han Hye Seung, Kim Joon Mee, Kim Hwal Woong, Chang Hee Kyung, Choi Young Hee, Park Ji Y, Gu Mi Jin, Lhee Min Jin, Kim Jung Yeon, Kim Hee Sung, Cho Mee-Yon, , |
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Telomere shortening in non-tumorous and tumor mucosa is independently related to colorectal carcinogenesis in precancerous lesions.
International journal of molecular epidemiology and genetics 2017 8 (5): 53-58. Park Won-Jin, Bae Sung Uk, Heo Yu-Ran, Jung Soo-Jung, Lee Jae- |
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Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Dec . Shia Jinru, Schultz Nikolaus, Kuk Deborah, Vakiani Efsevia, Middha Sumit, Segal Neil H, Hechtman Jaclyn F, Berger Michael F, Stadler Zsofia K, Weiser Martin R, Wolchok Jedd D, Boland C Richard, Gönen Mithat, Klimstra David |
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Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
The oncologist 2016 Sep . Rankin Andrew, Klempner Samuel J, Erlich Rachel, Sun James X, Grothey Axel, Fakih Marwan, George Thomas J, Lee Jeeyun, Ross Jeffrey S, Stephens Philip J, Miller Vincent A, Ali Siraj M, Schrock Alexa |
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Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival.
Oncotarget 2016 Aug 7 (34): 55098-55109. Mima Kosuke, Nowak Jonathan A, Qian Zhi Rong, Cao Yin, Song Mingyang, Masugi Yohei, Shi Yan, da Silva Annacarolina, Gu Mancang, Li Wanwan, Hamada Tsuyoshi, Zhang Xuehong, Wu Kana, Meyerhardt Jeffrey A, Baba Hideo, Giovannucci Edward L, Chan Andrew T, Fuchs Charles S, Ogino Shuji, Nishihara Rei |
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Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.
Cancer research and treatment : official journal of Korean Cancer Association 2016 Jul . Kim Kyu-Pyo, Kim Jeong-Eun, Hong Yong Sang, Ahn Sung-Min, Chun Sung Min, Hong Seung-Mo, Jang Se Jin, Yu Chang Sik, Kim Jin Cheon, Kim Tae W |
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Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors with 2 or More Somatic Mutations in Mismatch Repair Genes.
Gastroenterology 2016 Jun . Cohen Stacey A, Turner Emily H, Beightol Mallory B, Jacobson Angela, Gooley Ted A, Salipante Stephen J, Haraldsdottir Sigurdis, Smith Christina, Scroggins Sheena, Tait Jonathan F, Grady William M, Lin Edward H, Cohn David E, Goodfellow Paul J, Arnold Mark W, de la Chapelle Albert, Pearlman Rachel, Hampel Heather, Pritchard Colin |
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Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma.
The Journal of pathology 2016 Jun . Tetzlaff Michael T, Singh Rajesh R, Seviour Elena G, Curry Jonathan L, Hudgens Courtney W, Bell Diana, Wimmer Daniel A, Ning Jing, Czerniak Bogdan A, Zhang Li, Davies Michael A, Prieto Victor G, Broaddus Russell R, Ram Prahlad, Luthra Rajyalakshmi, Esmaeli Bi |
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Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.
Gut 2016 May . Masugi Yohei, Nishihara Reiko, Yang Juhong, Mima Kosuke, da Silva Annacarolina, Shi Yan, Inamura Kentaro, Cao Yin, Song Mingyang, Nowak Jonathan A, Liao Xiaoyun, Nosho Katsuhiko, Chan Andrew T, Giannakis Marios, Bass Adam J, Hodi F Stephen, Freeman Gordon J, Rodig Scott, Fuchs Charles S, Qian Zhi Rong, Ogino Shu |
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MicroRNA <i>MIR21</i> (miR-21) and PTGS2 expression in colorectal cancer and patient survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Mar . Mima Kosuke, Nishihara Reiko, Yang Juhong, Dou Ruoxu, Masugi Yohei, Shi Yan, da Silva Annacarolina, Cao Yin, Song Mingyang, Nowak Jonathan, Gu Mancang, Li Wanwan, Morikawa Teppei, Zhang Xuehong, Wu Kana, Baba Hideo, Giovannucci Edward L, Meyerhardt Jeffrey A, Chan Andrew T, Fuchs Charles S, Qian Zhi Rong, Ogino Shu |
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BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis.
PloS one 2016 11 (3): e0151865. Nam Soo Kyung, Yun Sumi, Koh Jiwon, Kwak Yoonjin, Seo An Na, Park Kyoung Un, Kim Duck-Woo, Kang Sung-Bum, Kim Woo Ho, Lee Hye Seu |
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Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis.
Scientific reports 2016 6 22982. Bria E, Pilotto S, Simbolo M, Fassan M, de Manzoni G, Carbognin L, Sperduti I, Brunelli M, Cataldo I, Tomezzoli A, Mafficini A, Turri G, Karachaliou N, Rosell R, Tortora G, Scarpa |
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Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer.
International journal of cancer 2016 12 139 (11): 2493-501. Takahashi Yayoi, Sugai Tamotsu, Habano Wataru, Ishida Kazuyuki, Eizuka Makoto, Otsuka Koki, Sasaki Akira, Takayuki Matsumoto , Morikawa Takanori, Unno Michiaki, Suzuki Hiro |
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Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Annals of surgical oncology 2015 Oct . Chang Shih-Ching, Lin Pei-Ching, Lin Jen-Kou, Lin Chien-Hsing, Yang Shung-Haur, Liang Wen-Yi, Chen Wei-Shone, Jiang Jeng-K |
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Mutational profiling of colorectal cancers with microsatellite instability.
Oncotarget 2015 Oct . Lin Elaine I, Tseng Li-Hui, Gocke Christopher D, Reil Stacy, Le Dung T, Azad Nilofer S, Eshleman James |
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Prognostic utility of molecular factors by age at diagnosis of colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Oct . McCleary Nadine J, Sato Kaori, Nishihara Reiko, Inamura Kentaro, Morikawa Teppei, Zhang Xuehong, Wu Kana, Yamauchi Mai, Kim Sun A, Sukawa Yasutaka, Mima Kosuke, Qian Zhi Rong, Fuchs Charles S, Ogino Shuji, Meyerhardt Jeffrey |
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Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival.
The American journal of clinical nutrition 2015 Sep . Lochhead Paul, Nishihara Reiko, Qian Zhi Rong, Mima Kosuke, Cao Yin, Sukawa Yasutaka, Kim Sun A, Inamura Kentaro, Zhang Xuehong, Wu Kana, Giovannucci Edward, Meyerhardt Jeffrey A, Chan Andrew T, Fuchs Charles S, Ogino Shu |
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Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer.
British journal of cancer 2015 Sep 113 (6): 979-88. Jorissen Robert N, Christie Michael, Mouradov Dmitri, Sakthianandeswaren Anuratha, Li Shan, Love Christopher, Xu Zheng-Zhou, Molloy Peter L, Jones Ian T, McLaughlin Stephen, Ward Robyn L, Hawkins Nicholas J, Ruszkiewicz Andrew R, Moore James, Burgess Antony W, Busam Dana, Zhao Qi, Strausberg Robert L, Lipton Lara, Desai Jayesh, Gibbs Peter, Sieber Oliver |
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Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers.
Journal of surgical oncology 2015 Jun 111 (7): 905-10. Lan Yuan-Tzu, Jen-Kou Lin, Lin Chien-Hsing, Yang Shung-Haur, Lin Chun-Chi, Wang Huann-Sheng, Chen Wei-Shone, Lin Tzu-Chen, Jiang Jeng-Kai, Chang Shih-Chi |
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Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2015 Jun 28 (6): 836-44. Stelloo Ellen, Bosse Tjalling, Nout Remi A, MacKay Helen J, Church David N, Nijman Hans W, Leary Alexandra, Edmondson Richard J, Powell Melanie E, Crosbie Emma J, Kitchener Henry C, Mileshkin Linda, Pollock Pamela M, Smit Vincent T, Creutzberg Carien |
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Molecular analysis of isolated tumor glands from endometrial endometrioid adenocarcinomas.
Pathology international 2015 May 65 (5): 240-9. Suga Yasuko, Sugai Tamotsu, Uesugi Noriyuki, Kawasaki Tomonori, Fukagawa Tomoyuki, Yamamoto Eiichiro, Ishida Kazuyuki, Suzuki Hiromu, Sugiyama To |
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Novel molecular insights from routine genotyping of colorectal carcinomas.
Human pathology 2015 Apr 46 (4): 507-13. Stachler Matthew D, Rinehart Elizabeth, Lindeman Neal, Odze Robert, Srivastava Amita |
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[Molecular analysis of sporadic colon cancer].
Revista médica de Chile 2015 Mar 143 (3): 310-9. Hurtado Claudia, Wielandt Ana María, Zárate Alejandro J, Kronberg Udo, Castro Magdalena, Yamagiwa Ken, Ito Takashi, Eishi Yoshinobu, Contreras Luis, López-Köstner Francis |
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Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.
Oncotarget 2015 Mar 6 (9): 7209-20. Mitsuhashi Kei, Nosho Katsuhiko, Sukawa Yasutaka, Matsunaga Yasutaka, Ito Miki, Kurihara Hiroyoshi, Kanno Shinichi, Igarashi Hisayoshi, Naito Takafumi, Adachi Yasushi, Tachibana Mami, Tanuma Tokuma, Maguchi Hiroyuki, Shinohara Toshiya, Hasegawa Tadashi, Imamura Masafumi, Kimura Yasutoshi, Hirata Koichi, Maruyama Reo, Suzuki Hiromu, Imai Kohzoh, Yamamoto Hiroyuki, Shinomura Yasuhi |
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PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer.
Cancer medicine 2015 Mar 4 (3): 371-82. Manceau Gilles, Marisa Laetitia, Boige Valérie, Duval Alex, Gaub Marie-Pierre, Milano Gérard, Selves Janick, Olschwang Sylviane, Jooste Valérie, le Legrain Michè, Lecorre Delphine, Guenot Dominique, Etienne-Grimaldi Marie-Christine, Kirzin Sylvain, Martin Laurent, Lepage Come, Bouvier Anne-Marie, Laurent-Puig Pier |
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Genetic mechanisms in interval colon cancers.
Digestive diseases and sciences 2014 Sep 59 (9): 2255-63. Richter James M, Pino Maria Simona, Austin Thomas R, Campbell Emily, Szymonifka Jackie, Russo Andrea L, Hong Theodore S, Borger Darrell, Iafrate A John, Chung Daniel |
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ERBB2 gene as a potential therapeutic target in small bowel adenocarcinoma.
European journal of cancer (Oxford, England : 1990) 2014 Jul 50 (10): 1740-6. Laforest Anais, Aparicio Thomas, Zaanan Aziz, Silva Fabio Pittella, Didelot Audrey, Desbeaux Aurélien, Le Corre Delphine, Benhaim Leonor, Pallier Karine, Aust Daniela, Pistorius Steffen, Blons Hélène, Svrcek Magali, Laurent-Puig Pier |
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DNA content analysis of colorectal cancer defines a distinct 'microsatellite and chromosome stable' group but does not predict response to radiotherapy.
International journal of experimental pathology 2014 Feb 95 (1): 16-23. Fadhil Wakkas, Kindle Karin, Jackson Darryl, Zaitoun Abed, Lane Nina, Robins Adrian, Ilyas Mohamm |
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Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Molecular cancer 2014 13 (1): 135. Imamura Yu, Lochhead Paul, Yamauchi Mai, Kuchiba Aya, Qian Zhi Rong, Liao Xiaoyun, Nishihara Reiko, Jung Seungyoun, Wu Kana, Nosho Katsuhiko, Wang Yaoyu E, Peng Shouyong, Bass Adam J, Haigis Kevin M, Meyerhardt Jeffrey A, Chan Andrew T, Fuchs Charles S, Ogino Shu |
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Descriptive profile of PIK3CA-mutated colorectal cancer in postmenopausal women.
International journal of colorectal disease 2013 Dec 28 (12): 1637-42. Phipps Amanda I, Makar Karen W, Newcomb Polly |
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Oncogenic mutations and microsatellite instability phenotype predict specific anatomical subsite in colorectal cancer patients.
European journal of human genetics : EJHG 2013 Dec 21 (12): 1383-8. Corso Giovanni, Pascale Valeria, Flauti Giuseppe, Ferrara Francesco, Marrelli Daniele, Roviello Fran |
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Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.
Journal of the National Cancer Institute 2013 Dec 105 (23): 1789-98. Ogino Shuji, Liao Xiaoyun, Imamura Yu, Yamauchi Mai, McCleary Nadine J, Ng Kimmie, Niedzwiecki Donna, Saltz Leonard B, Mayer Robert J, Whittom Renaud, Hantel Alexander, Benson Al B, Mowat Rex B, Spiegelman Donna, Goldberg Richard M, Bertagnolli Monica M, Meyerhardt Jeffrey A, Fuchs Charles S, |
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Prognostic and putative predictive biomarkers of gastric cancer for personalized medicine.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2013 Sep 22 (3): 127-37. Warneke Viktoria S, Behrens Hans-Michael, Haag Jochen, Balschun Katharina, Böger Christine, Becker Thomas, Ebert Matthias P A, Lordick Florian, Röcken Christo |
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Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.
Journal of the National Cancer Institute 2013 Aug 105 (15): 1151-6. Lochhead Paul, Kuchiba Aya, Imamura Yu, Liao Xiaoyun, Yamauchi Mai, Nishihara Reiko, Qian Zhi Rong, Morikawa Teppei, Shen Jeanne, Meyerhardt Jeffrey A, Fuchs Charles S, Ogino Shu |
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Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy ± cetuximab.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Aug 19 (15): 4104-13. Smith Christopher G, Fisher David, Claes Bart, Maughan Timothy S, Idziaszczyk Shelley, Peuteman Gilian, Harris Rebecca, James Michelle D, Meade Angela, Jasani Bharat, Adams Richard A, Kenny Sarah, Kaplan Richard, Lambrechts Diether, Cheadle Jeremy |
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Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.
British journal of cancer 2013 Jul 109 (2): 408-15. Murata A, Baba Y, Watanabe M, Shigaki H, Miyake K, Ishimoto T, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Nosho K, Baba |
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PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Jun 19 (12): 3285-96. Day Fiona L, Jorissen Robert N, Lipton Lara, Mouradov Dmitri, Sakthianandeswaren Anuratha, Christie Michael, Li Shan, Tsui Cary, Tie Jeannie, Desai Jayesh, Xu Zheng-Zhou, Molloy Peter, Whitehall Vicki, Leggett Barbara A, Jones Ian T, McLaughlin Stephen, Ward Robyn L, Hawkins Nicholas J, Ruszkiewicz Andrew R, Moore James, Busam Dana, Zhao Qi, Strausberg Robert L, Gibbs Peter, Sieber Oliver |
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Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry.
American journal of surgery 2013 May 205 (5): 608-12; discussion 612. Gawlick Ute, Lu Kim C, Douthit Miriam A, Diggs Brian S, Schuff Kathryn G, Herzig Daniel O, Tsikitis Vassiliki |
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A clinical-biological risk stratification model for resected gastric cancer: prognostic impact of Her2, Fhit, and APC expression status.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2013 Mar 24 (3): 693-701. Bria E, De Manzoni G, Beghelli S, Tomezzoli A, Barbi S, Di Gregorio C, Scardoni M, Amato E, Frizziero M, Sperduti I, Corbo V, Brunelli M, Bersani S, Tortora G, Scarpa |
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Pattern of clinically relevant mutations in consecutive series of Russian colorectal cancer patients.
Medical oncology (Northwood, London, England) 2013 30 (3): 686. Yanus Grigoriy A, Belyaeva Anna V, Ivantsov Alexandr O, Kuligina Ekatherina Sh, Suspitsin Evgeny N, Mitiushkina Natalia V, Aleksakhina Svetlana N, Iyevleva Aglaya G, Zaitseva Olga A, Yatsuk Olga S, Gorodnova Tatiana V, Strelkova Tatiana N, Efremova Sofia A, Lepenchuk Alla Yu, Ochir-Garyaev Altn N, Paneyah Moisey B, Matsko Dmitriy E, Togo Alexandr V, Imyanitov Evgeny |
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PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival.
PloS one 2013 8 (6): e65479. Rosty Christophe, Young Joanne P, Walsh Michael D, Clendenning Mark, Sanderson Kristy, Walters Rhiannon J, Parry Susan, Jenkins Mark A, Win Aung Ko, Southey Melissa C, Hopper John L, Giles Graham G, Williamson Elizabeth J, English Dallas R, Buchanan Daniel |
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Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.
Cancer biomarkers : section A of Disease markers 2013 13 (5): 359-66. Kang Melissa, Shen Xiang J, Kim Sangmi, Araujo-Perez Felix, Galanko Joseph A, Martin Chris F, Sandler Robert S, Keku Temitope |
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Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
The New England journal of medicine 2012 Oct 367 (17): 1596-606. Liao Xiaoyun, Lochhead Paul, Nishihara Reiko, Morikawa Teppei, Kuchiba Aya, Yamauchi Mai, Imamura Yu, Qian Zhi Rong, Baba Yoshifumi, Shima Kaori, Sun Ruifang, Nosho Katsuhiko, Meyerhardt Jeffrey A, Giovannucci Edward, Fuchs Charles S, Chan Andrew T, Ogino Shu |
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Improved risk assessment of endometrial cancer by combined analysis of MSI, PI3K-AKT, Wnt/?-catenin and P53 pathway activation.
Gynecologic oncology 2012 Sep 126 (3): 466-73. Nout Remi A, Bosse Tjalling, Creutzberg Carien L, Jürgenliemk-Schulz Ina M, Jobsen Jan J, Lutgens Ludy C H W, van der Steen-Banasik Elzbieta M, van Eijk Ronald, Ter Haar Natalja T, Smit Vincent T H B |
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Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Sep 18 (17): 4753-63. Imamura Yu, Morikawa Teppei, Liao Xiaoyun, Lochhead Paul, Kuchiba Aya, Yamauchi Mai, Qian Zhi Rong, Nishihara Reiko, Meyerhardt Jeffrey A, Haigis Kevin M, Fuchs Charles S, Ogino Shu |
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Use of mutation profiles to refine the classification of endometrial carcinomas.
The Journal of pathology 2012 Sep 228 (1): 20-30. McConechy Melissa K, Ding Jiarui, Cheang Maggie C U, Wiegand Kimberly C, Senz Janine, Tone Alicia A, Yang Winnie, Prentice Leah M, Tse Kane, Zeng Thomas, McDonald Helen, Schmidt Amy P, Mutch David G, McAlpine Jessica N, Hirst Martin, Shah Sohrab P, Lee Cheng-Han, Goodfellow Paul J, Gilks C Blake, Huntsman David |
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Oncogenic PIK3CA mutations in colorectal cancers and polyps.
International journal of cancer. Journal international du cancer 2012 Aug 131 (4): 813-20. Whitehall Vicki L J, Rickman Celestine, Bond Catherine E, Ramsnes Ingunn, Greco Sonia A, Umapathy Aarti, McKeone Diane, Faleiro Rebecca J, Buttenshaw Ron L, Worthley Daniel L, Nayler Sam, Zhao Zhen Zhen, Montgomery Grant W, Mallitt Kylie-Ann, Jass Jeremy R, Matsubara Nagahide, Notohara Kenji, Ishii Tatsuhiro, Leggett Barbara |
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Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum.
Gut 2012 Jun 61 (6): 847-54. Yamauchi Mai, Morikawa Teppei, Kuchiba Aya, Imamura Yu, Qian Zhi Rong, Nishihara Reiko, Liao Xiaoyun, Waldron Levi, Hoshida Yujin, Huttenhower Curtis, Chan Andrew T, Giovannucci Edward, Fuchs Charles, Ogino Shu |
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Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Apr 18 (8): 2257-68. Liao Xiaoyun, Morikawa Teppei, Lochhead Paul, Imamura Yu, Kuchiba Aya, Yamauchi Mai, Nosho Katsuhiko, Qian Zhi Rong, Nishihara Reiko, Meyerhardt Jeffrey A, Fuchs Charles S, Ogino Shu |
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FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.
PloS one 2012 7 (2): e30801. Byron Sara A, Gartside Michael, Powell Matthew A, Wellens Candice L, Gao Feng, Mutch David G, Goodfellow Paul J, Pollock Pamela |
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Molecular alterations associated with liver metastases development in colorectal cancer patients.
British journal of cancer 2011 Jul 105 (2): 281-7. Bruin S C, He Y, Mikolajewska-Hanclich I, Liefers G-J, Klijn C, Vincent A, Verwaal V J, de Groot K A, Morreau H, van Velthuysen M-L F, Tollenaar R A E M, van 't Veer L |
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KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Mar 17 (5): 1122-30. Tie Jeanne, Lipton Lara, Desai Jayesh, Gibbs Peter, Jorissen Robert N, Christie Michael, Drummond Katharine J, Thomson Benjamin N J, Usatoff Valery, Evans Peter M, Pick Adrian W, Knight Simon, Carne Peter W G, Berry Roger, Polglase Adrian, McMurrick Paul, Zhao Qi, Busam Dana, Strausberg Robert L, Domingo Enric, Tomlinson Ian P M, Midgley Rachel, Kerr David, Sieber Oliver |
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Oncogenic mutations in gastric cancer with microsatellite instability.
European journal of cancer (Oxford, England : 1990) 2011 Feb 47 (3): 443-51. Corso Giovanni, Velho Sérgia, Paredes Joana, Pedrazzani Corrado, Martins Diana, Milanezi Fernanda, Pascale Valeria, Vindigni Carla, Pinheiro Hugo, Leite Marina, Marrelli Daniele, Sousa Sónia, Carneiro Fátima, Oliveira Carla, Roviello Franco, Seruca Raqu |
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Oncogenic mutations in MAPK cascade as novel molecular biomarkers for treatment of gastric cancer patients with EGFR inhibitors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 39. Corso G, Marrelli D, Pascale V, Garosi L, Velho S, Seruca R, Roviello |
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TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers.
PloS one 2011 6 (9): e25062. Shima Kaori, Morikawa Teppei, Yamauchi Mai, Kuchiba Aya, Imamura Yu, Liao Xiaoyun, Meyerhardt Jeffrey A, Fuchs Charles S, Ogino Shu |
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Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Carcinogenesis 2010 Sep 31 (9): 1604-11. Slattery Martha L, Herrick Jennifer S, Lundgreen Abbie, Fitzpatrick Francis A, Curtin Karen, Wolff Roger |
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NRAS mutations are rare in colorectal cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2010 Sep 19 (3): 157-63. Irahara Natsumi, Baba Yoshifumi, Nosho Katsuhiko, Shima Kaori, Yan Liying, Dias-Santagata Dora, Iafrate Anthony John, Fuchs Charles S, Haigis Kevin M, Ogino Shu |
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CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.
International journal of cancer. Journal international du cancer 2010 Jun 126 (12): 2863-73. Firestein Ron, Shima Kaori, Nosho Katsuhiko, Irahara Natsumi, Baba Yoshifumi, Bojarski Emeric, Giovannucci Edward L, Hahn William C, Fuchs Charles S, Ogino Shu |
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DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
PloS one 2010 5 (11): e13978. Berg Marianne, Danielsen Stine A, Ahlquist Terje, Merok Marianne A, Ågesen Trude H, Vatn Morten H, Mala Tom, Sjo Ole H, Bakka Arne, Moberg Ingvild, Fetveit Torunn, Mathisen Øystein, Husby Anders, Sandvik Oddvar, Nesbakken Arild, Thiis-Evensen Espen, Lothe Ragnhild |
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The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type.
Journal of experimental & clinical cancer research : CR 2010 29 (1): 32. Barbi Stefano, Cataldo Ivana, De Manzoni Giovanni, Bersani Samantha, Lamba Simona, Mattuzzi Silvia, Bardelli Alberto, Scarpa Al |
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A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Gastroenterology 2009 Nov 137 (5): 1609-20.e1-3. Nosho Katsuhiko, Kure Shoko, Irahara Natsumi, Shima Kaori, Baba Yoshifumi, Spiegelman Donna, Meyerhardt Jeffrey A, Giovannucci Edward L, Fuchs Charles S, Ogino Shu |
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Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009 Oct 18 (10): 2765-72. Kure Shoko, Nosho Katsuhiko, Baba Yoshifumi, Irahara Natsumi, Shima Kaori, Ng Kimmie, Meyerhardt Jeffrey A, Giovannucci Edward L, Fuchs Charles S, Ogino Shu |
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Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Sep 27 (27): 4591-8. Ogino Shuji, Nosho Katsuhiko, Irahara Natsumi, Shima Kaori, Baba Yoshifumi, Kirkner Gregory J, Meyerhardt Jeffrey A, Fuchs Charles |
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PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Mar 27 (9): 1477-84. Ogino Shuji, Nosho Katsuhiko, Kirkner Gregory J, Shima Kaori, Irahara Natsumi, Kure Shoko, Chan Andrew T, Engelman Jeffrey A, Kraft Peter, Cantley Lewis C, Giovannucci Edward L, Fuchs Charles |
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PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Neoplasia (New York, N.Y.) 2008 Jun 10 (6): 534-41. Nosho Katsuhiko, Kawasaki Takako, Ohnishi Mutsuko, Suemoto Yuko, Kirkner Gregory J, Zepf Dimity, Yan Liying, Longtine Janina A, Fuchs Charles S, Ogino Shu |
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Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.
International journal of cancer. Journal international du cancer 2008 May 122 (10): 2255-9. Barault Ludovic, Veyrie Nicolas, Jooste Valerie, Lecorre Delphine, Chapusot Caroline, Ferraz Jean-Marc, Lièvre Astrid, Cortet Marion, Bouvier Anne-Marie, Rat Patrick, Roignot Patrick, Faivre Jean, Laurent-Puig Pierre, Piard Francoi |
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BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
BMC cancer 2008 8 (1): 255. Velho Sérgia, Moutinho Cátia, Cirnes Luís, Albuquerque Cristina, Hamelin Richard, Schmitt Fernando, Carneiro Fátima, Oliveira Carla, Seruca Raqu |
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Assessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies.
OncoTargets and therapy 0 8 3265-3276. Tang Jie-Ting, Wang Zhen-Hua, Fang Jing-Yu |
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BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS phenotype in metastatic colorectal cancer.
Cancer genomics & proteomics 0 8 (1): 15-8. Qiu Jinghua, Compagnone Marion, Laibe Sophy, Lagarde Arnaud, Goncalves Anthony, Turrini Olivier, Xerri Luc, Monges Geneviève, Olschwang Sylvia |
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