Records 1 - 9
| Development of population pharmacokinetics model of icotinib with non-linear absorption characters in healthy Chinese volunteers to assess the CYP2C19 polymorphism and food-intake effect.
European journal of clinical pharmacology 2015 Jul 71 (7): 843-50.
Hu Pei, Chen Jia, Liu Dongyang, Zheng Xin, Zhao Qian, Jiang
| Interaction between smoking and CYP2C19*3 polymorphism increased risk of lung cancer in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Jun 35 (6): 5295-8.
Yan Fei, Xu Jin-Fu, Liu Xiao-fang, Li Xing-H
| Therapeutic effects and adverse drug reactions are affected by icotinib exposure and CYP2C19 and EGFR genotypes in Chinese non-small cell lung cancer patients.
Asian Pacific journal of cancer prevention : APJCP 2014 15 (17): 7195-200.
Chen Jia, Zheng Xin, Liu Dong-Yang, Zhao Qian, Wu Yi-Wen, Tan Fen-Lai, Wang Yin-Xiang, Jiang Ji, Hu P
| CYP2C19 genotype-based phase I studies of a c-Met inhibitor tivantinib in combination with erlotinib, in advanced/metastatic non-small cell lung cancer.
British journal of cancer 2013 Nov 109 (11): 2803-9.
Yamamoto N, Murakami H, Hayashi H, Fujisaka Y, Hirashima T, Takeda K, Satouchi M, Miyoshi K, Akinaga S, Takahashi T, Nakagawa
| The effect of CYP2C19 polymorphism on the safety, tolerability, and pharmacokinetics of tivantinib (ARQ 197): results from a phase I trial in advanced solid tumors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2013 Jun 24 (6): 1653-9.
Yamamoto N, Murakami H, Nishina T, Hirashima T, Sugio K, Muro K, Takahashi T, Naito T, Yasui H, Akinaga S, Koh Y, Boku
| Poor metabolizers at the cytochrome P450 2C19 loci is at increased risk of developing cancer in Asian populations.
PloS one 2013 8 (8): e73126.
Wang Hong, Song Kang, Chen Zenggan, Yu Yanm
| Effect of the CYP2C19 genotype on the pharmacokinetics of icotinib in healthy male volunteers.
European journal of clinical pharmacology 2012 Dec 68 (12): 1677-80.
Ruan Can-Jun, Liu Dong-Yang, Jiang Ji, Hu P
| CYP450 polymorphisms predict clinic outcomes to vinorelbine-based chemotherapy in patients with non-small-cell lung cancer.
Acta oncologica (Stockholm, Sweden) 2007 46 (3): 361-6.
Pan Ji-Hong, Han Jin-Xiang, Wu Jian-Mei, Sheng Li-Jun, Huang Hai-N
| Frequencies of poor metabolizers of cytochrome P450 2C19 in esophagus cancer, stomach cancer, lung cancer and bladder cancer in Chinese population.
World journal of gastroenterology : WJG 2004 Jul 10 (13): 1961-3.
Shi Wei-Xing, Chen Shu-Qi